A. Elson

发表

Gene dosage and down's syndrome: Metabolic and enzymatic changes in PC12 cells overexpressing transfected human liver-type phosphofructokinase

H. Degani, H. Ben‐Hur, A. Elson, 1992, Somatic cell and molecular genetics.

Modelling the role of dual specificity phosphatases in Herceptin resistant breast cancer cell lines

J. Schwartz, L. Tabernero, A. Elson, 2019, bioRxiv.

Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice.

P. Leder, C. Deng, C. Kozak, 1995, Genes & development.

Neu-mediated phosphorylation of protein tyrosine phosphatase epsilon is critical for activation of Src in mammary tumor cells

A. Elson, D. Berman-Golan, 2007, Oncogene.

Protein tyrosine phosphatase epsilon activates Yes and Fyn in Neu-induced mammary tumor cells.

A. Elson, Shira Granot-Attas, 2004, Experimental cell research.

Selective loss of dopaminergic nigro-striatal neurons in brains of Atm-deficient mice.

Y. Shiloh, A. Elson, Y. Groner, 1998, Proceedings of the National Academy of Sciences of the United States of America.

The PTPROt tyrosine phosphatase functions as an obligate haploinsufficient tumor suppressor in vivo in B-cell chronic lymphocytic leukemia

M. Kramer, A. Elson, E. Arman, 2017, Oncogene.

Epidermal Growth Factor Receptor (EGFR)-mediated Positive Feedback of Protein-tyrosine Phosphatase ϵ (PTPϵ) on ERK1/2 and AKT Protein Pathways Is Required for Survival of Human Breast Cancer Cells*

R. Pulido, A. Elson, C. Nunes-Xavier, 2011, The Journal of Biological Chemistry.

Genetic interactions between atm and p53 influence cellular proliferation and irradiation-induced cell cycle checkpoints.

P. Leder, C. Westphal, D. Fisher, 1997, Cancer research.

atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity

P. Leder, C. Westphal, D. Fisher, 1997, Nature Genetics.

Protein tyrosine phosphatase ε increases the risk of mammary hyperplasia and mammary tumors in transgenic mice

A. Elson, 1999, Oncogene.

Cytosolic Protein Tyrosine Phosphatase-ε Is a Negative Regulator of Insulin Signaling in Skeletal Muscle

S. Aga-Mizrachi, A. Bak, S. Sampson, 2008 .

Receptor Protein Tyrosine Phosphatase α–Mediated Enhancement of Rheumatoid Synovial Fibroblast Signaling and Promotion of Arthritis in Mice

N. Bottini, G. Firestein, J. den Hertog, 2015, Arthritis & rheumatology.

Production of Osteoclasts for Studying Protein Tyrosine Phosphatase Signaling.

A. Elson, E. Finkelshtein, Einat Levy-Apter, 2016, Methods in molecular biology.

Protein tyrosine phosphatases ε and α perform nonredundant roles in osteoclasts

R. Baron, J. den Hertog, S. Lotinun, 2014, Molecular Biology of the Cell.

Cytosolic protein tyrosine phosphatase-epsilon is a negative regulator of insulin signaling in skeletal muscle.

S. Aga-Mizrachi, A. Bak, S. Sampson, 2008, Endocrinology.

Phosphatidylinositol 5-phosphate 4-kinase

F. Tamanoi, K. Jacobson, Mark A Sussman, 2012 .

The protein tyrosine phosphatase epsilon gene maps to mouse chromosome 7 and human chromosome 10q26.

P. Leder, S. Weremowicz, C. Morton, 1996, Genomics.

Dimerization In Vivo and Inhibition of the Nonreceptor Form of Protein Tyrosine Phosphatase Epsilon

J. den Hertog, A. Elson, Z. Tiran, 2003, Molecular and Cellular Biology.

Phosphorylation-dependent Regulation of Kv2.1 Channel Activity at Tyrosine 124 by Src and by Protein-tyrosine Phosphatase ε*

B. Attali, A. Elson, A. Peretz, 2003, The Journal of Biological Chemistry.

Regulation of Protein-tyrosine Phosphatases α and ε by Calpain-mediated Proteolytic Cleavage*

A. Elson, G. Volohonsky, H. Gil-Henn, 2001, The Journal of Biological Chemistry.

Generation of novel cytoplasmic forms of protein tyrosine phosphatase epsilon by proteolytic processing and translational control

A. Elson, G. Volohonsky, H. Gil-Henn, 2000, Oncogene.

Hypomyelination and increased activity of voltage‐gated K+ channels in mice lacking protein tyrosine phosphatase ϵ

B. Attali, A. Elson, A. Peretz, 2000, The EMBO journal.

The transmembranal and cytoplasmic forms of protein tyrosine phosphatase epsilon physically associate with the adaptor molecule Grb2

A. Elson, Hila Toledano-Katchalski, 1999, Oncogene.

The origins and formation of bone-resorbing osteoclasts.

A. Elson, N. Reuven, A. Anuj, 2022, Bone.

Role of OSCAR Signaling in Osteoclastogenesis and Bone Disease

J. Bella, J. Hoyland, A. Elson, 2021, Frontiers in Cell and Developmental Biology.

Kinetic Modeling of DUSP Regulation in Herceptin-Resistant HER2-Positive Breast Cancer

J. Schwartz, L. Tabernero, A. Elson, 2019, Genes.

Adaptor Protein GRB2 Promotes Src Tyrosine Kinase Activation and Podosomal Organization by Protein-tyrosine Phosphatase ϵ in Osteoclasts*

S. Li, M. Bedford, A. Elson, 2014, The Journal of Biological Chemistry.

Protein tyrosine phosphatase alpha inhibits hypothalamic leptin receptor signaling and regulates body weight in vivo

Y. Kuperman, I. Spiegel, A. Elson, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Overexpression of liver-type phosphofructokinase (PFKL) in transgenic-PFKL mice: implication for gene dosage in trisomy 21.

A. Elson, D. Levanon, Y. Groner, 1994, The Biochemical journal.

Whole mount analysis of mammary gland structure in PTP epsilon transgenic mice.

A. Elson, Z. Tiran, 2003, Methods in enzymology.

Site-Selective Regulation of Platelet-Derived Growth Factor β Receptor Tyrosine Phosphorylation by T-Cell Protein Tyrosine Phosphatase

C. Heldin, F. Haj, B. Neel, 2004, Molecular and Cellular Biology.

Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells

Ari Elson, Kfir Lapid, Orit Kollet, 2006, Nature Medicine.

Multifaceted Modulation of K+ Channels by Protein-tyrosine Phosphatase ϵ Tunes Neuronal Excitability*

B. Attali, A. Elson, A. Peretz, 2012, The Journal of Biological Chemistry.

Protein tyrosine phosphatases as novel targets in breast cancer therapy.

R. Pulido, J. Martín-Pérez, A. Elson, 2013, Biochimica et biophysica acta.

Protein tyrosine phosphatases in health and disease

R. Pulido, J. den Hertog, A. Elson, 2013, The FEBS journal.

Protein-tyrosine Phosphatase ϵ

A. Elson, Philip Leder, 1995, The Journal of Biological Chemistry.

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice.

P. Leder, C. Morton, A. Elson, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Stepping out of the shadows: Oncogenic and tumor-promoting protein tyrosine phosphatases.

A. Elson, 2017, The international journal of biochemistry & cell biology.

Protein tyrosine phosphatases: functional inferences from mouse models and human diseases

A. Elson, S. Harroch, W. Hendriks, 2008, The FEBS journal.

Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice.

P. Leder, A. Elson, Y. Wang, 1997, Proceedings of the National Academy of Sciences of the United States of America.

PCAF Lysine Acetyltransferase

F. Tamanoi, K. Jacobson, Mark A Sussman, 2008 .

Modelling the role of dual specificity phosphatases in Herceptin resistant breast cancer cell lines

Jean-Marc Schwartz, Petronela Buiga, Ari Elson, 2019, bioRxiv.

Regulation of dual specificity phosphatases in breast cancer during initial treatment with Herceptin: a Boolean model analysis

Jean-Marc Schwartz, Petronela Buiga, Ari Elson, 2018, BMC Systems Biology.

Metabolic regulation by protein tyrosine phosphatases

A. Elson, H. Knobler, 2014, Journal of biomedical research.

Protein tyrosine phosphatase epsilon and Neu-induced mammary tumorigenesis

A. Elson, D. Berman-Golan, Shira Granot-Attas, 2008, Cancer and Metastasis Reviews.

Protein Tyrosine Phosphatase Epsilon as a Regulator of Body Weight and Glucose Metabolism

A. Elson, 2013 .

Protein Tyrosine Phosphatase ε is a Negative Regulator of FcεRI‐mediated Mast Cell Responses

T. Katagiri, K. Mizuno, H. Yakura, 2009, Scandinavian journal of immunology.

The roles of protein tyrosine phosphatases in bone-resorbing osteoclasts.

A. Elson, M. Shalev, 2019, Biochimica et biophysica acta. Molecular cell research.

The MMTV/c-myc transgene and p53 null alleles collaborate to induce T-cell lymphomas, but not mammary carcinomas in transgenic mice.

L. Donehower, P. Leder, C. Deng, 1995, Oncogene.

Tyrosine Phosphatase-ε Activates Src and Supports the Transformed Phenotype of Neu-induced Mammary Tumor Cells*

A. Elson, H. Gil-Henn, 2003, The Journal of Biological Chemistry.

Protein Tyrosine Phosphatase E Inhibits Signaling by Mitogen-Activated Protein Kinases

G. Shohat, A. Elson, Y. Yung, 2003 .

Protein tyrosine phosphatase epsilon regulates integrin-mediated podosome stability in osteoclasts by activating Src.

A. Elson, Chen Luxenburg, Shira Granot-Attas, 2009, Molecular biology of the cell.

PTPϵ has a critical role in signaling transduction pathways and phosphoprotein network topology in red cells

S. Perrotta, R. Deana, A. Brunati, 2008, Proteomics.

Phosphorylation of the phosphatase PTPROt at Tyr399 is a molecular switch that controls osteoclast activity and bone mass in vivo

J. Tuckermann, M. Bedford, A. Elson, 2019, Science Signaling.

Elevated Cu/Zn‐SOD exacerbates radiation sensitivity and hematopoietic abnormalities of Atm‐deficient mice

Y. Shiloh, J. Lotem, A. Elson, 2001, The EMBO journal.

Regulation of receptor-type protein tyrosine phosphatases by their C-terminal tail domains.

T. Olender, M. Bedford, A. Elson, 2016, Biochemical Society transactions.

The structure of the human liver-type phosphofructokinase gene.

A. Elson, Y. Bernstein, D. Levanon, 1990, Genomics.

Sorting Nexin 10 as a Key Regulator of Membrane Trafficking in Bone-Resorbing Osteoclasts: Lessons Learned From Osteopetrosis

B. Geiger, S. Winograd-Katz, J. Tuckermann, 2021, Frontiers in Cell and Developmental Biology.

An SNX10-dependent mechanism down-regulates fusion between mature osteoclasts.

B. Geiger, S. Winograd-Katz, J. Tuckermann, 2021, Journal of cell science.

Massive osteopetrosis caused by non-functional osteoclasts in R51Q SNX10 mutant mice.

B. Geiger, S. Winograd-Katz, J. Tuckermann, 2020, Bone.

R51Q SNX10 induces osteopetrosis by promoting uncontrolled fusion of monocytes to form giant, non-functional osteoclasts

B. Geiger, S. Winograd-Katz, J. Tuckermann, 2018, bioRxiv.

R51Q SNX10 induces osteopetrosis by promoting uncontrolled fusion of monocytes to form giant, non-functional osteoclasts

B. Geiger, S. Winograd-Katz, J. Tuckermann, 2018, bioRxiv.

Protein kinase C (PKC) level is increased in PC12 cells overexpressing transfected liver‐type phosphofructokinase

A. Elson, Y. Groner, Y. Weiss, 1994, Biology of the cell.

Protein-tyrosine phosphatase epsilon regulates Shc signaling in a kinase-specific manner: increasing coherence in tyrosine phosphatase signaling.

W. Muller, A. Elson, J. Kraut-Cohen, 2008, Journal of Biological Chemistry.

A mutant EGF‐receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling

Y. Yarden, T. Jovin, M. Katz, 2002, The EMBO journal.

Potassium Channel Amplitude and Kinetics of a Neuronal Voltage-Gated Tyrosine Phosphorylation Modulates Current

B. Attali, E. Blalock, N. Porter, 2015 .

Protein tyrosine phosphatases in osteoclast differentiation, adhesion, and bone resorption.

Ari Elson, A. Elson, Shira Granot-Attas, 2008, European journal of cell biology.

Nuclear Localization of Non-receptor Protein Tyrosine Phosphatase ϵ Is Regulated by Its Unique N-Terminal Domain

A. Elson, G. Volohonsky, Hila Toledano-Katchalski, 2002 .

Association of Tyrosine Phosphatase Epsilon with Microtubules Inhibits Phosphatase Activity and Is Regulated by the Epidermal Growth Factor Receptor

A. Elson, Shira Granot-Attas, Tal Sines, 2007, Molecular and Cellular Biology.

Comparative study of protein tyrosine phosphatase-epsilon isoforms: membrane localization confers specificity in cellular signalling.

J. Clausen, J. Andersen, N. Møłler, 2001, The Biochemical journal.

Identification of a cytoplasmic, phorbol ester-inducible isoform of protein tyrosine phosphatase epsilon.

P. Leder, A. Elson, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Expression Profiling during Mammary Epithelial Cell Three-Dimensional Morphogenesis Identifies PTPRO as a Novel Regulator of Morphogenesis and ErbB2-Mediated Transformation

P. Boutros, L. Muthuswamy, Irina Kalatskaya, 2012, Molecular and Cellular Biology.

Tyrosine Phosphatases ε and α Perform Specific and Overlapping Functions in Regulation of Voltage-gated Potassium Channels in Schwann Cells

B. Attali, J. Sap, A. Elson, 2006 .

Tyrosine phosphatases epsilon and alpha perform specific and overlapping functions in regulation of voltage-gated potassium channels in Schwann cells.

B. Attali, J. Sap, A. Elson, 2006, Molecular biology of the cell.

Protein tyrosine phosphatase epsilon affects body weight by downregulating leptin signaling in a phosphorylation-dependent manner.

Alon Chen, R. Klinghoffer, Y. Kuperman, 2011, Cell metabolism.

Comparative study of protein tyrosine phosphatase-ε isoforms : membrane localization confers specificity in cellular signalling

J. Clausen, J. Andersen, R. Lammers, 2022 .

Regulation of protein-tyrosine phosphatases alpha and epsilon by calpain-mediated proteolytic cleavage.

A. Elson, G. Volohonsky, H. Gil-Henn, 2001, The Journal of biological chemistry.

PTPe (RPTPe and Cyt-PTPe)

F. Tamanoi, K. Jacobson, Mark A Sussman, 2012 .

Nuclear localization of non-receptor protein tyrosine phosphatase epsilon is regulated by its unique N-terminal domain.

A. Elson, G. Volohonsky, Hila Toledano-Katchalski, 2002, Experimental cell research.

Transmitter Release Novel Opener Dampens Neuronal Firing and Pre- and Postsynaptic Activation of M-Channels By a

Y. Yaari, J. Delgado-García, B. Attali, 2013 .

Abstracts of the 15th Annual Meeting of the Israel Society for Neuroscience Eilat, Israel, December 3–5, 2006

Leslie G. Ungerleider, D. Amit, H. Seung, 2006, Neural Plasticity.

Tyrosine phosphatase epsilon is a positive regulator of osteoclast function in vitro and in vivo.

R. Chiusaroli, R. Baron, A. Harmelin, 2003, Molecular biology of the cell.

PTPRJ promotes osteoclast maturation and activity by inhibiting Cbl‐mediated ubiquitination of NFATc1 in late osteoclastogenesis

J. Tuckermann, A. Elson, V. Brumfeld, 2021, The FEBS journal.

Protein tyrosine phosphatase epsilon inhibits signaling by mitogen-activated protein kinases.

G. Shohat, A. Elson, Y. Yung, 2003, Molecular cancer research : MCR.

Tyrosine phosphatase-epsilon activates Src and supports the transformed phenotype of Neu-induced mammary tumor cells.

A. Elson, H. Gil-Henn, 2003, The Journal of biological chemistry.

Protein tyrosine phosphatase epsilon increases the risk of mammary hyperplasia and mammary tumors in transgenic mice.

A. Elson, 1999, Oncogene.

BASP1 down-regulates RANKL-induced osteoclastogenesis.

A. Elson, N. Reuven, Stefan G. E. Roberts, 2023, Experimental Cell Research.

Protein tyrosine phosphatases in health and disease

R. Pulido, J. den Hertog, A. Elson, 2013, The FEBS journal.

Editorial: Developmental Biology and Regulation of Osteoclasts

N. Levaot, N. Sims, A. Elson, 2021, Frontiers in Cell and Developmental Biology.