M. Selby

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5' end-dependent translation initiation of hepatitis C viral RNA and the presence of putative positive and negative translational control elements within the 5' untranslated region.

M. Houghton, J. Han, B. J. Yoo, 1992, Virology.

Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells.

C. Walker, M. Selby, J. Baenziger, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Distribution of DNA Vaccines Determines Their Immunogenicity After Intramuscular Injection in Mice1

D. McDonald, J. Ulmer, J. Donnelly, 2000, The Journal of Immunology.

Anti-CTLA-4 Antibodies of IgG2a Isotype Enhance Antitumor Activity through Reduction of Intratumoral Regulatory T Cells

A. Korman, M. Quigley, M. Selby, 2013, Cancer Immunology Research.

FcγRs Modulate the Anti-tumor Activity of Antibodies Targeting the PD-1/PD-L1 Axis.

A. Korman, J. Ravetch, M. Selby, 2015, Cancer cell.

Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates.

Israel Lowy, Mark Selby, Drew M Pardoll, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Hepatitis C virus: structure, protein products and processing of the polyprotein precursor.

M. Houghton, A. Weiner, Q. Choo, 1994, Current studies in hematology and blood transfusion.

Processing of the native nerve growth factor precursor to form biologically active nerve growth factor.

W. Rutter, R. Edwards, M. Selby, 1988, The Journal of biological chemistry.

Cutting Edge: Accelerated Autoimmune Diabetes in the Absence of LAG-3

C. Drake, A. Korman, M. Selby, 2011, The Journal of Immunology.

Cationic microparticles are a potent delivery system for a HCV DNA vaccine.

M. Houghton, Manmohan J. Singh, S. Coates, 2004, Vaccine.

Induction of Broad CD4+ and CD8+ T-Cell Responses and Cross- Neutralizing Antibodies against Hepatitis C Virus by Vaccination with Th1-Adjuvanted Polypeptides Followed by Defective Alphaviral Particles Expressing Envelope Glycoproteins gpE1 and gpE2 and Nonstructural Proteins 3, 4, and 5

M. Houghton, S. Coates, J. Polo, 2008, Journal of Virology.

Mouse nerve growth factor gene: structure and expression

W. Rutter, F. Sharp, R. Edwards, 1987, Molecular and cellular biology.

Characterization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia viruses

M. Houghton, R. Ralston, Q. Choo, 1993, Journal of virology.

Cationic lipids direct a viral glycoprotein into the class I major histocompatibility complex antigen-presentation pathway.

M. Selby, A. Erickson, C. Walker, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Mechanisms of action of DNA vaccines.

C. Walker, J. Ulmer, M. Selby, 1998, Expert opinion on investigational drugs.

Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression

C. Bieberich, C. Drake, A. D. De Marzo, 2021, Nature Cancer.

Castration-mediated IL-8 Promotes Myeloid Infiltration and Prostate Cancer Progression

C. Bieberich, C. Drake, A. D. De Marzo, 2019, bioRxiv.

Combining Intra-Tumoral Treg Depletion with Androgen Deprivation Therapy (ADT): Pre-Clinical Activity in the Myc-CaP Model

C. Drake, A. Korman, M. Selby, 2017, Prostate Cancer and Prostatic Diseases.

Combination of tim-4 antagonist and methods of use

M. Selby, E. Chadwick, Sean P. Doyle, 2017 .

The highly polymorphic region near the human insulin gene is composed of simple tandemly repeating sequences

W. Rutter, G. Bell, M. Selby, 1982, Nature.

HP_A_196301 1..16

M. Selby, W. Chan, E. Gonsalves, 2019 .

Aryl hydrocarbon receptor acts as a tumor suppressor in a syngeneic MC38 colon carcinoma tumor model

M. Selby, W. Chan, Poonam Yakkundi, 2019, Hypoxia.

Immunogenicity by Electroporation In Vivo Increased DNA Vaccine Delivery and

J. Ulmer, M. Selby, D. Rabussay, 2000 .

A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target.

A. Pearson, C. Drake, S. Tomlins, 2020, The Journal of clinical investigation.

Complex processing and protein:protein interactions in the E2:NS2 region of HCV.

M. Houghton, F. Masiarz, M. Selby, 1994, Virology.

Activation of the grp78 andgrp94 Promoters by Hepatitis C Virus E2 Envelope Protein

M. Houghton, Y. Fong, Q. Choo, 1999, Journal of Virology.

New epitopes in ovalbumin provide insights for cancer neoepitopes.

J. Sidney, A. Sette, P. Srivastava, 2019, JCI insight.

Identification of epitopes in ovalbumin that provide insights for cancer neoepitopes

J. Sidney, A. Sette, P. Srivastava, 2019 .

Elective Nodal Irradiation Attenuates the Combinatorial Efficacy of Stereotactic Radiation Therapy and Immunotherapy

C. Drake, T. DeWeese, A. Korman, 2018, Clinical Cancer Research.

Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy.

P. Oefner, J. Cleveland, S. Ong, 2019, Cell reports.

Expression of LAG‐3 and efficacy of combination treatment with anti‐LAG‐3 and anti‐PD‐1 monoclonal antibodies in glioblastoma

J. Taube, C. Drake, P. Burger, 2018, International journal of cancer.

A Randomized, Double-Blind, Placebo-Controlled Assessment of BMS-936558, a Fully Human Monoclonal Antibody to Programmed Death-1 (PD-1), in Patients with Chronic Hepatitis C Virus Infection

K. Reddy, Jeffrey Anderson, I. Lowy, 2013, PloS one.

Relative Potency of Cellular and Humoral Immune Responses Induced by DNA Vaccination

J. Ulmer, M. Selby, G. Otten, 2001, Intervirology.

Injection in Mice Their Immunogenicity After Intramuscular Distribution of DNA Vaccines Determines

D. McDonald, J. Ulmer, J. Donnelly, 2000 .

Increased DNA Vaccine Delivery and Immunogenicity by Electroporation In Vivo

J. Ulmer, M. Selby, D. Rabussay, 2000, The Journal of Immunology.

Activation of the grp 78 and grp 94 Promoters by Hepatitis C Virus E 2 Envelope Protein

M. Houghton, Y. Fong, Q. Choo, 1998 .

Virus-specific cytotoxic T-lymphocyte activity elicited by coimmunization with human immunodeficiency virus type 1 genes regulated by the bacteriophage T7 promoter and T7 RNA polymerase protein

C. Walker, M. Selby, B. Doe, 1997, Journal of virology.

STRUCTURE OF PRECURSORS DERIVED FROM THE SEQUENCES OF CLONED cDNAs

W. Rutter, G. Bell, P. Hobart, 1983 .

The Hepatitis C Virus: Genetic Organization, Persistence, and Vaccine Strategies

B. Walker, M. Houghton, A. Weiner, 1994 .

Characterization ofHepatitis C VirusEnvelope Glycoprotein Complexes Expressed byRecombinant Vaccinia Viruses

M. Houghton, R. Ralston, M. Selby, 1993 .

Analysis of a major human chorionic somatomammotropin gene. Evidence for two functional promoter elements.

N. Eberhardt, J. Baxter, A. Barta, 1984, The Journal of biological chemistry.

Doxepin versus diazepam: a controlled evaluation in 100 chronic alcoholic patients.

R. Phillips, M. Selby, D. Gallant, 1969, The Journal of clinical pharmacology and the journal of new drugs.

Structure of a mouse submaxillary messenger RNA encoding epidermal growth factor and seven related proteins.

W. Rutter, G. Bell, M. Selby, 1983, Science.

Differential RNA splicing predicts two distinct nerve growth factor precursors

W. Rutter, R. Edwards, M. Selby, 1986, Nature.

Preclinical Characterization of Relatlimab, a Human LAG-3–Blocking Antibody, Alone or in Combination with Nivolumab

A. Korman, J. Zorn, R. T. Bunch, 2022, bioRxiv.

Hepatitis C virus core and E2 protein expression in transgenic mice

F. Chisari, M. Houghton, J. Chung, 1997, Hepatology.

Synthesis of a novel hepatitis C virus protein by ribosomal frameshift

Zhenming Xu, M. Selby, J. Ou, 2001, The EMBO journal.

Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology

A. Korman, R. Johnston, M. Quigley, 2016, PloS one.

In Vitro Characterization of the Anti-PD-1 Antibody Nivolumab, BMS-936558, and In Vivo Toxicology in Non-Human Primates

A. Korman, R. T. Bunch, M. Selby, 2014, Cancer Immunology Research.

Temporally Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune Escape

E. Mardis, R. Schreiber, A. Korman, 2017, Cancer Immunology Research.

TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM

Christopher M. Jackson, A. Korman, D. Pardoll, 2018, Oncoimmunology.

THE GROWTH HORMONE GENE FAMILY: STRUCTURE, EVOLUTION, EXPRESSION, AND REGULATION

N. Eberhardt, M. Karin, J. Baxter, 1982 .

Microenvironment and Immunology Immune Inhibitory Molecules Lag-3 and Pd-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape

Peter Vogel, Matthew P Smeltzer, David M Gravano, 2022 .

Hepatitis C virus polyprotein vaccine formulations capable of inducing broad antibody and cellular immune responses.

M. Houghton, Manmohan J. Singh, S. Coates, 2006, The Journal of general virology.

Transfection of a differentiated human hepatoma cell line (Huh7) with in vitro-transcribed hepatitis C virus (HCV) RNA and establishment of a long-term culture persistently infected with HCV

G. Nuovo, M. Houghton, J. Choe, 1995, Journal of virology.

Comparative studies of the core gene products of two different hepatitis C virus isolates: two alternative forms determined by a single amino acid substitution.

M. Selby, S. Lo, J. Ou, 1994, Virology.

Structure, sequence, and position of the stem-loop in tar determine transcriptional elongation by tat through the HIV-1 long terminal repeat.

P. Luciw, B. Peterlin, M. Selby, 1989, Genes & development.

Increased Expression and Immunogenicity of Sequence-Modified Human Immunodeficiency Virus Type 1 gag Gene

Mary Schaefer, Mark Selby, C. Greer, 2000, Journal of Virology.

Hepatitis C virus envelope glycoprotein E1 originates in the endoplasmic reticulum and requires cytoplasmic processing for presentation by class I MHC molecules.

P. Parham, M. Houghton, C. Walker, 1999, Journal of immunology.

Synergism between Tat and VP16 in trans-activation of HIV-1 LTR.

B. Peterlin, M. Selby, S. Ghosh, 1993, Journal of molecular biology.

HIV-1 Tat trans-activates in the Absence of its Target

B. Peterlin, M. Selby, 1991 .

Trans-activation by HIV-1 Tat via a heterologous RNA binding protein

B. Peterlin, M. Selby, 1990, Cell.

Isolation and nucleotide sequence of a cDNA encoding the precursor of mouse nerve growth factor

W. Rutter, G. Bell, M. Selby, 1983, Nature.

Expression, identification and subcellular localization of the proteins encoded by the hepatitis C viral genome.

M. Houghton, Q. Choo, M. Selby, 1993, The Journal of general virology.

FcγRs Modulate the Anti-tumor Activity of Antibodies Targeting the PD-1/PD-L1 Axis.

A. Korman, J. Ravetch, M. Selby, 2015, Cancer cell.

Hepatitis C virus envelope glycoprotein E1 originates in the endoplasmic reticulum and requires cytoplasmic processing for presentation by class I MHC molecules.

P. Parham, M. Houghton, C. Walker, 1999, Journal of immunology.

This information is current as Presentation by Class I MHC Molecules Requires Cytoplasmic Processing for andOriginates in the Endoplasmic Reticulum Hepatitis C Virus Envelope Glycoprotein E 1

P. Parham, M. Houghton, C. Walker, 1998 .

The hepatitis C virus encodes a serine protease involved in processing of the putative nonstructural proteins from the viral polyprotein precursor.

M. Houghton, F. Masiarz, Q. Choo, 1993, Biochemical and biophysical research communications.

Interleukin-21 combined with PD-1 or CTLA-4 blockade enhances antitumor immunity in mouse tumor models

A. Korman, S. Dillon, M. Selby, 2017, Oncoimmunology.

Role of the immunoglobulin constant region in the antitumor activity of antibodies to cytotoxic T-lymphocyte antigen-4 (CTLA-4).

A. Korman, R. Yordanova, M. Selby, 2013 .

Antitumor activity of concurrent blockade of immune checkpoint molecules CTLA-4 and PD-1 in preclinical models.

A. Korman, M. Quigley, M. Selby, 2013 .

Microenvironment and Immunology Immune InhibitoryMolecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape

C. Liu, C. Drake, G. Netto, 2012 .

Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model

C. Drake, A. Korman, M. Selby, 2017, Prostate Cancer and Prostatic Diseases.

Activity of Anti-PD-1 in Murine Tumor Models: Role of “Host” PD-L1 and Synergistic Effect of Anti-PD-1 and Anti-CTLA-4 (48.37)

A. Korman, M. Selby, Linda Wu, 2007, The Journal of Immunology.

Diabetes in the Absence of LAG-3 Cutting Edge: Accelerated Autoimmune

C. Drake, A. Korman, M. Selby, 2011 .

Fc g Rs Modulate the Anti-t umor Activity of Antibodies Targeting the PD-1 / PD-L 1 Axis Graphical Abstract Highlights

John, J. Ravetch, M. Selby, 2015 .

Processing and secretion of nerve growth factor: expression in mammalian cells with a vaccinia virus vector

W. Rutter, R. Edwards, W. Mobley, 1988, Molecular and cellular biology.

Fc-Optimized Anti-CCR8 Antibody Depletes Regulatory T Cells in Human Tumor Models

N. Siemers, A. Korman, M. Selby, 2021, Cancer Research.

Induction of Broad and Potent Anti-Human Immunodeficiency Virus Immune Responses in Rhesus Macaques by Priming with a DNA Vaccine and Boosting with Protein-Adsorbed Polylactide Coglycolide Microparticles

J. Ulmer, J. Donnelly, Manmohan J. Singh, 2003, Journal of Virology.

Induction of herpes simplex virus gB-specific cytotoxic T lymphocytes in TAP1-deficient mice by genetic immunization but not HSV infection.

C. Walker, M. Selby, K. Hartog, 2001, Virology.

Interaction between hepatitis C virus core protein and E1 envelope protein

M. Selby, S. Lo, J. Ou, 1996, Journal of virology.

Erratum to: Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma

C. Drake, P. Tran, D. Pardoll, 2016, Journal of Immunotherapy for Cancer.

Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma

C. Drake, P. Tran, D. Pardoll, 2015, Journal of Immunotherapy for Cancer.

Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma

Christopher M. Jackson, C. Drake, D. Pardoll, 2015, Journal of Immunotherapy for Cancer.

Characterization of Hepatitis C Virus Core-Specific Immune Responses Primed in Rhesus Macaques by a Nonclassical ISCOM Vaccine

M. Houghton, M. Selby, P. Ng, 2001, The Journal of Immunology.

VaccineRhesus Macaques by a Nonclassical ISCOM Core-Specific Immune Responses Primed in Characterization of Hepatitis C Virus

M. Houghton, M. Selby, P. Ng, 2001 .

Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

J. Taube, C. Drake, Lieping Chen, 2023, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

The biosynthesis and processing of proteins in the mouse 7S nerve growth factor complex.

E. Shooter, W. Rutter, M. Selby, 1983, Cold Spring Harbor symposia on quantitative biology.

Correction: Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology

A. Korman, R. Johnston, M. Quigley, 2016, PloS one.

Nonclinical evaluation of the combination of mouse IL-21 and anti- mouse CTLA-4 or PD-1 blocking antibodies in mouse tumor models.

A. Korman, S. Dillon, M. Selby, 2013 .

Intrahepatic Genetic Inoculation of Hepatitis C Virus RNA Confers Cross-Protective Immunity

M. Houghton, A. Weiner, S. Rosenberg, 2001, Journal of Virology.

Enhancement of DNA vaccine potency by electroporation in vivo.

J. Ulmer, M. Selby, C. Goldbeck, 2000, Journal of biotechnology.

Cobra nerve growth factor: Structure and evolutionary comparison

W. Rutter, R. Edwards, M. Selby, 1987, Journal of neuroscience research.

[17] Isolation of complementary DNA encoding mouse nerve growth factor and epidermal growth factor

G. Bell, M. Selby, James Scott, 1987 .

Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates.

J. Taube, C. Drake, Lieping Chen, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

In Vitro Characterization of the Anti-PD-1 Antibody Nivolumab, BMS-936558, and In Vivo Toxicology in Non-Human Primates

A. Korman, M. Selby, Susan Wong, 2014, Cancer Immunology Research.

Human immunodeficiency virus type 1 Tat does not transactivate mature trans-acting responsive region RNA species in the nucleus or cytoplasm of primate cells

B. Peterlin, D. Chin, M. Selby, 1991, Journal of virology.

Temporally Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune Escape

E. Mardis, R. Schreiber, A. Korman, 2017, Cancer Immunology Research.

Abstract SY09-01: Next-generation anti-CTLA-4 antibodies

A. Korman, R. Vuyyuru, M. Selby, 2017 .