Y. Hwang

发表

trans-Dominant suppressor mutations of the H-ras oncogene.

D. Blair, Y. Ogiso, L. Gutiérrez, 1990, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

The identification of a domain in Escherichia coli elongation factor Tu that interacts with elongation factor Ts.

Y. Hwang, D. Miller, M. Carter, 1992, The Journal of biological chemistry.

An ELISA DYRK1A non-radioactive assay suitable for the characterization of inhibitors.

Y. Hwang, T. Adayev, Yong Liu, 2017, F1000Research.

An ELISA DYRK1A non-radioactive kinase assay suitable for the characterization of inhibitors

Y. Hwang, T. Adayev, Yong Liu, 2017, F1000Research.

Effect of DYRK1A activity inhibition on development of neuronal progenitors isolated from Ts65Dn mice

J. Wegiel, W. Kaczmarski, A. Golabek, 2012, Journal of neuroscience research.

Phosphorylation by Dyrk1A of Clathrin Coated Vesicle-Associated Proteins: Identification of the Substrate Proteins and the Effects of Phosphorylation

W. Xie, Y. Hwang, D. Bolton, 2012, PloS one.

Humoral immune response to fibrillar β-amyloid peptide

P. Mehta, Y. Hwang, D. Miller, 2003 .

Inhibition of SDC25 C-domain-induced guanine-nucleotide exchange by guanine ring binding domain mutants of v-H-ras.

P. Poullet, Y. Hwang, A. Parmeggiani, 1993, The Journal of biological chemistry.

A study of the kinetic mechanism of elongation factor Ts.

Y. Hwang, D. Miller, D. Miller, 1985, The Journal of biological chemistry.

Phosphorylation of Amphiphysin I by Minibrain Kinase/Dual-specificity Tyrosine Phosphorylation-regulated Kinase, a Kinase Implicated in Down Syndrome*

W. Xie, Y. Hwang, A. Wieraszko, 2006, Journal of Biological Chemistry.

Mnb/Dyrk1A phosphorylation regulates the interaction of dynamin 1 with SH3 domain-containing proteins.

J. Padovan, G. Dolios, Y. Hwang, 2004, Biochemistry.

Biological activity of a K-ras mutant that contains the 12R/59T/116Y mutations.

Y. Ogiso, Y. Hwang, T. Y. Shih, 1993, Cancer letters.

Humoral immune response to fibrillar beta-amyloid peptide.

J. Wegiel, P. Mehta, Y. Hwang, 2003, Biochemistry.

Correlation of 3,4-dihydroxybutyl 1-phosphonate resistance with a defect in cardiolipin synthesis in Escherichia coli

Y. Hwang, B. Tropp, R. Engel, 1984, Journal of bacteriology.

Dynamin Is a Minibrain Kinase/Dual Specificity Yak1-related Kinase 1A Substrate*

Y. Hwang, M. Elzinga, M. Chen-Hwang, 2002, The Journal of Biological Chemistry.

Form of dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A nonphosphorylated at tyrosine 145 and 147 is enriched in the nuclei of astroglial cells, adult hippocampal progenitors, and some cholinergic axon terminals

A. Golabek, Y. Hwang, A. Rabe, 2011, Neuroscience.

Ras Interaction with Two Distinct Binding Domains in Raf-1 5 Be Required for Ras Transformation (*)

M. White, C. Der, R. Khosravi‐Far, 1996, The Journal of Biological Chemistry.

Activity-dependent phosphorylation of dynamin 1 at serine 857.

J. Wegiel, Hui-Ming Zhu, W. Xie, 2012, Biochemistry.

The Differential Effects of the Gly-60 to Ala Mutation on the Interaction of H-Ras p21 with Different Downstream Targets (*)

Y. Hwang, Y. Sung, Mo-Chou Chen Hwang, 1996, The Journal of Biological Chemistry.

Intracellular distribution of differentially phosphorylated dual‐specificity tyrosine phosphorylation‐regulated kinase 1A (DYRK1A)

J. Wegiel, P. Mehta, G. Albertini, 2014, Journal of neuroscience research.

The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome

J. Wegiel, B. Reisberg, T. Wisniewski, 2008, Acta Neuropathologica.

The Dominant Negative Effects of H-Ras Harboring a Gly to Ala Mutation at Position 60*

Y. Hwang, Y. Sung, Mo-Chou Chen Hwang, 1996, The Journal of Biological Chemistry.

Switching Nucleotide Specificity of Ha-Ras p21 by a Single Amino Acid Substitution at Aspartate 119 (*)

Y. Hwang, Jielai Zhong, M. Chen-Hwang, 1995, The Journal of Biological Chemistry.

Cell type- and brain structure-specific patterns of distribution of minibrain kinase in human brain

J. Wegiel, B. Reisberg, T. Wisniewski, 2004, Brain Research.

Link Between DYRK1A Overexpression and Several-Fold Enhancement of Neurofibrillary Degeneration With 3-Repeat Tau Protein in Down Syndrome

J. Wegiel, B. Reisberg, M. D. de Leon, 2011, Journal of neuropathology and experimental neurology.

Dyrk1A binds to multiple endocytic proteins required for formation of clathrin-coated vesicles.

Y. Hwang, D. Bolton, N. Murakami, 2009, Biochemistry.

Increased Dosage of Dyrk1A Alters Alternative Splicing Factor (ASF)-regulated Alternative Splicing of Tau in Down Syndrome*♦

J. Wegiel, Jianhua Shi, I. Grundke‐Iqbal, 2008, Journal of Biological Chemistry.

Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome

J. Wegiel, I. Grundke‐Iqbal, K. Iqbal, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

MNB/DYRK1A phosphorylation regulates the interactions of synaptojanin 1 with endocytic accessory proteins.

Y. Hwang, Rong Wang, T. Adayev, 2006, Biochemical and biophysical research communications.

Trisomy-driven overexpression of DYRK1A kinase in the brain of subjects with Down syndrome

J. Wegiel, Y. Hwang, T. Adayev, 2007, Neuroscience Letters.

Kinetic properties of a MNB/DYRK1A mutant suitable for the elucidation of biochemical pathways.

J. Wegiel, Y. Hwang, T. Adayev, 2006, Biochemistry.

Promotion of Neuronal Plasticity by (−)-Epigallocatechin-3-Gallate

W. Xie, Y. Hwang, A. Wieraszko, 2008, Neurochemical Research.

The role of DYRK1A in neurodegenerative diseases

J. Wegiel, C. Gong, Y. Hwang, 2011, The FEBS journal.

Mutagenesis of the H-ras p21 at glycine-60 residue disrupts GTP-induced conformational change.

Y. Hwang, Y. Sung, M. Carter, 1995, Biochemistry.

A Mutation That Hinders The GTP Induced Aminoacyl-tRNA BINDING of ELONGATION Factor TU

F. Jurnak, Y. Hwang, D. Miller, 1989 .

Harmine is an ATP-competitive inhibitor for dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A).

Jerzy Wegiel, J. Wegiel, Y. Hwang, 2011, Archives of biochemistry and biophysics.

Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro.

Y. Hwang, T. Adayev, D. Bolton, 2007, Biochemistry.

Design, synthesis, and biological evaluation of polyphenol derivatives as DYRK1A inhibitors. The discovery of a potentially promising treatment for Multiple Sclerosis.

Y. Hwang, Gian Luca Araldi, 2022, Bioorganic & medicinal chemistry letters.

Site-directed mutagenesis of the GDP binding domain of bacterial elongation factor Tu.

M. Innis, Y. Hwang, D. Miller, 1989, Archives of biochemistry and biophysics.

Two distinct mechanisms for regulation of nonmuscle myosin assembly via the heavy chain: phosphorylation for MIIB and mts 1 binding for MIIA.

Y. Hwang, L. Kotula, N. Murakami, 2000, Biochemistry.

The role of cysteinyl residues in the activity of bacterial elongation factor Ts, a guanosine nucleotide dissociation protein.

Y. Hwang, A. Sanchez, D. Miller, 1997, Archives of biochemistry and biophysics.

Cancer esearch apeutics , Targets , and Chemical Biology arcinogenic Effect of Capsaicin Involves Activation R GFR Signaling but Not TRPV 1

A. Bode, Z. Dong, K. Lee, 2010 .

A mutation that alters the nucleotide specificity of elongation factor Tu, a GTP regulatory protein.

Y. Hwang, D L Miller, Y W Hwang, 1987, The Journal of biological chemistry.

Abnormalities of DYRK1A-Cytoskeleton Complexes in the Blood Cells as Potential Biomarkers of Alzheimer’s Disease

A. Barczak, Y. Hwang, T. Gabryelewicz, 2019, Journal of Alzheimer's disease : JAD.

Development of Novel Fluorinated Polyphenols as Selective Inhibitors of DYRK1A/B Kinase for Treatment of Neuroinflammatory Diseases including Parkinson’s Disease

Y. Hwang, G. Araldi, 2023, Pharmaceuticals.

Gene dosage-dependent association of DYRK1A with the cytoskeleton in the brain and lymphocytes of down syndrome patients.

J. Wegiel, W. Kaczmarski, Y. Hwang, 2012, Journal of neuropathology and experimental neurology.

Mnb/Dyrk1A Phosphorylation Regulates the Interaction of Dynamin 1 with SH3 Domain-Containing Proteins†

J. Padovan, G. Dolios, Y. Hwang, 2004 .

The role of DYRK1A in neurodegenerative diseases

J. Wegiel, C. Gong, Y. Hwang, 2011, The FEBS journal.