Joseph Rosenbluh

发表

Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal

A. Graessmann, E. Waigmann, A. Loyter, 2009, Retrovirology.

Complementary information derived from CRISPR Cas9 mediated gene deletion and suppression

W. Hahn, D. Root, F. Vazquez, 2017, Nature Communications.

Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

W. Hahn, B. Weir, K. Kinzler, 2012, PLoS genetics.

RNF43 is frequently mutated in colorectal and endometrial cancers

Kristian Cibulskis, Joseph Rosenbluh, Gad Getz, 2014, Nature Genetics.

β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

Jill P. Mesirov, Joseph Rosenbluh, Aviad Tsherniak, 2012, Cell.

KRAS and YAP1 Converge to Regulate EMT and Tumor Survival

Joseph Rosenbluh, Arjun Bhutkar, William C. Hahn, 2014, Cell.

Translocation of histone proteins across lipid bilayers and Mycoplasma membranes.

A. Graessmann, A. Loyter, Joseph Rosenbluh, 2005, Journal of molecular biology.

A unified web platform for network-based analyses of genomic data

Ted E. Natoli, D. Thompson, N. Hacohen, 2017 .

KRAS and YAP 1 Converge to Regulate EMT and Tumor Survival Citation

W. Hahn, T. Jacks, D. Root, 2014 .

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

Jacob D. Jaffe, P. Tamayo, W. Hahn, 2016, Cell systems.

Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers.

J. Mesirov, P. Tamayo, W. Hahn, 2013, Cancer discovery.

Inwardly rectifying potassium channels mediate polymyxin-induced nephrotoxicity

J. Li, H. Coleman, H. Parkington, 2022, Cellular and Molecular Life Sciences.

The Plant VirE2 Interacting Protein 1. A Molecular Link between the Agrobacterium T-Complex and the Host Cell Chromatin?1

T. Tzfira, V. Citovsky, Jianxiong Li, 2005, Plant Physiology.

Permeabilized mammalian cells as an experimental system for nuclear import of geminiviral karyophilic proteins and of synthetic peptides derived from their nuclear localization signal regions.

A. Graessmann, R. Gilbertson, A. Loyter, 2006, The Journal of general virology.

Systematic loss of function screens identify pathway specific functional circular RNAs

G. Goodall, S. Conn, L. Perlaza-Jiménez, 2022, bioRxiv.

CRISPRi enables isoform-specific loss-of-function screens and identification of gastric cancer-specific isoform dependencies

P. Tan, R. Daly, D. Powell, 2021, Genome biology.

Characterizing genomic alterations in cancer by complementary functional associations

Gabriela Alexe, Chiara Romualdi, Pablo Tamayo, 2016, Nature Biotechnology.

Cancer Vulnerabilities Unveiled by Genomic Loss

Jill P. Mesirov, Joseph Rosenbluh, Aviad Tsherniak, 2012, Cell.

Cancer Vulnerabilities Unveiled by Genomic Loss Citation

J. Mesirov, W. Hahn, R. Beroukhim, 2012 .

Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM

Yonghong Xiao, Joseph Rosenbluh, Ian F. Dunn, 2010, Proceedings of the National Academy of Sciences.

RMRP Is a Non-Coding RNA Essential for Early Murine Development

W. Hahn, Kwok-Kin Wong, Joseph Rosenbluh, 2011, PloS one.

GeNets: A unified web platform for network-based analyses of genomic data

Bang Wong, Aviv Regev, Yang Li, 2018, Nature Methods.

Chromatin interactome mapping at 139 independent breast cancer risk signals

D. Easton, A. Antoniou, N. Waddell, 2019, Genome Biology.

CRISPR screens identify gene targets and drug repositioning opportunities at breast cancer risk loci

G. Chenevix-Trench, J. Beesley, K. McCue, 2021, bioRxiv.

GeNets: a unified web platform for network-based genomic analyses

Bang Wong, Jill P. Mesirov, Aviv Regev, 2018, Nature Methods.

BSA conjugates bearing multiple copies of the basic domain of HIV-1 Tat: Prototype for the development of multitarget inhibitors of extracellular Tat.

A. Loyter, Joseph Rosenbluh, M. Rusnati, 2010, Antiviral research.

β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

J. Mesirov, W. Hahn, W. Goessling, 2013, Cell.

Genomic insights into WNT/β-catenin signaling.

Joseph Rosenbluh, William C Hahn, W. Hahn, 2014, Trends in pharmacological sciences.

Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium

Joseph Rosenbluh, Zvi Hayouka, Mario Lebendiker, 2007, Proceedings of the National Academy of Sciences.

Integration of HIV-1 DNA Is Regulated by Interplay between Viral Rev and Cellular LEDGF/p75 Proteins

A. Friedler, A. Loyter, A. Levin, 2010, Molecular medicine.

Heritable methylation marks associated with prostate cancer risk

G. Giles, M. Southey, R. Milne, 2023, Familial Cancer.

Positively charged peptides can interact with each other, as revealed by solid phase binding assays.

Joseph Rosenbluh, Marco Rusnati, Antonella Bugatti, 2006, Analytical biochemistry.

Direct translocation of histone molecules across cell membranes

A. Graessmann, C. Gilon, A. Loyter, 2003, Journal of Cell Science.

Peptides derived from HIV‐1 Rev inhibit HIV‐1 integrase in a shiftide mechanism

A. Friedler, Michal Maes, A. Loyter, 2008, Biopolymers.

CRISPR screens identify gene targets at breast cancer risk loci

G. Chenevix-Trench, J. Beesley, K. McCue, 2023, Genome Biology.

Non-endocytic penetration of core histones into petunia protoplasts and cultured cells: a novel mechanism for the introduction of macromolecules into plant cells.

Sunil Kumar Singh, A. Graessmann, A. Loyter, 2004, Biochimica et biophysica acta.

Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities.

Matthew D. Dun, M. Monje, P. Ekert, 2023, Cancer cell.

Engineered Plant‐Based Nanocellulose Hydrogel for Small Intestinal Organoid Growth

W. H. Chan, V. Raghuwanshi, G. Garnier, 2020, Advanced science.

Interaction between HIV-1 Rev and Integrase Proteins

A. Friedler, A. Hizi, M. Kotler, 2007, Journal of Biological Chemistry.

Functional analysis of backbone cyclic peptides bearing the arm domain of the HIV-1 Rev protein: characterization of the karyophilic properties and inhibition of Rev-induced gene expression.

C. Gilon, A. Loyter, Joseph Rosenbluh, 2005, Biochemistry.

Technological Convergence: Highlighting the Power of CRISPR Single-Cell Perturbation Toolkit for Functional Interrogation of Enhancers

Nigel H. Lovell, N. Lovell, Joseph Rosenbluh, 2023, Cancers.

Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription

K. Harvey, T. Tang, Joseph Rosenbluh, 2023, bioRxiv.