D. Persaud

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The challenge of viral reservoirs in HIV-1 infection.

R. Siliciano, J. Blankson, D. Persaud, 2002, Annual review of medicine.

HIV-1 drug resistance profiles in children and adults with viral load of <50 copies/ml receiving combination therapy.

R. Siliciano, T. Quinn, R. D’Aquila, 2001, JAMA.

Genotypic analysis of HIV-1 drug resistance at the limit of detection: virus production without evolution in treated adults with undetectable HIV loads.

Tara L. Kieffer, R. Siliciano, K. Broman, 2004, The Journal of infectious diseases.

A stable latent reservoir for HIV-1 in resting CD4(+) T lymphocytes in infected children.

R. Siliciano, J. Margolick, T. Pierson, 2000, The Journal of clinical investigation.

Pediatric HIV: the Potential of Immune Therapeutics to Achieve Viral Remission and Functional Cure

N. Haigwood, G. Fouda, D. Persaud, 2020, Current HIV/AIDS Reports.

Effectiveness of antiretroviral therapy among HIV-infected children in sub-Saharan Africa.

W. Moss, D. Persaud, J. V. van Dijk, 2008, The Lancet. Infectious diseases.

Neruodevelopmental Outcomes in Preschool Children Living With HIV-1 Subtypes A and D in Uganda

M. Boivin, N. Nakasujja, D. Persaud, 2018, The Pediatric Infectious Disease Journal.

Recommendations for analytical antiretroviral treatment interruptions in HIV research trials-report of a consensus meeting.

B. Walker, D. Kuritzkes, J. Martinez-Picado, 2019, The lancet. HIV.

Use of Dried-Blood-Spot Samples and In-House Assays To Identify Antiretroviral Drug Resistance in HIV-Infected Children in Resource-Constrained Settings

B. Simen, L. Khaki, D. Persaud, 2011, Journal of Clinical Microbiology.

Very early combination antiretroviral therapy in infants: prospects for cure

D. Persaud, K. Luzuriaga, K. Rainwater-Lovett, 2015, Current opinion in HIV and AIDS.

Influence of age at virologic control on peripheral blood human immunodeficiency virus reservoir size and serostatus in perinatally infected adolescents.

D. Richman, G. Seage, D. Persaud, 2014, JAMA pediatrics.

Absence of HIV-1 after treatment cessation in an infant.

D. Persaud, K. Luzuriaga, 2014, The New England journal of medicine.

World Health Organization generic protocol to assess drug-resistant HIV among children <18 months of age and newly diagnosed with HIV in resource-limited countries.

L. Mofenson, D. Bennett, D. Persaud, 2012, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

CNS Persistence of HIV-1 in Children: the Untapped Reservoir

D. Persaud, Thor Wagner, A. Chahroudi, 2018, Current HIV/AIDS Reports.

B and T Cell Phenotypic Profiles of African HIV-Infected and HIV-Exposed Uninfected Infants: Associations with Antibody Responses to the Pentavalent Rotavirus Vaccine

B. Chi, J. Lindsey, R. Bosch, 2018, Front. Immunol..

Cholestatic hepatitis in children infected with the human immunodeficiency virus

W. Borkowsky, D. Persaud, S. Chandwani, 1993, The Pediatric infectious disease journal.

Human T-Lymphocyte Transformation with Human T-Cell Lymphotropic Virus Type 2

D. Persaud, W. Parks, E. Parks, 1998, Journal of Virology.

Differences in inducibility of the latent HIV reservoir in perinatal and adult infection

Lilly Siems, D. Persaud, R. B. Jones, 2020 .

Optimizing the World Health Organization algorithm for HIV vertical transmission risk assessment by adding maternal self-reported antiretroviral therapy adherence

V. Calvez, C. Giaquinto, P. Palma, 2022, BMC Public Health.

Delayed HIV detection among infants exposed to postnatal antiretroviral prophylaxis during breastfeeding

M. Hudgens, J. Nelson, D. Persaud, 2015, AIDS.

Time course and cytokine dependence of human T-cell lymphotropic virus type 1 T-lymphocyte transformation as revealed by a microtiter infectivity assay

D. Persaud, W. Parks, E. Parks, 1995, Journal of virology.

Clearance of adenoviral hepatitis with ribavirin therapy in a pediatric liver transplant recipient.

D. Persaud, P. Charache, R. Arav-Boger, 2000, The Pediatric infectious disease journal.

Novel Single-Cell-Level Phenotypic Assay for Residual Drug Susceptibility and Reduced Replication Capacity of Drug-Resistant Human Immunodeficiency Virus Type 1

R. Siliciano, J. Siliciano, Yan Zhou, 2004, Journal of Virology.

Continued Production of Drug-Sensitive Human Immunodeficiency Virus Type 1 in Children on Combination Antiretroviral Therapy Who Have Undetectable Viral Loads

Thomas C. Quinn, Douglas C. Watson, Robert F. Siliciano, 2004, Journal of Virology.

Defining cerebrospinal fluid HIV RNA escape: editorial review AIDS.

A. Winston, R. Price, S. Letendre, 2019, AIDS.

Intermittent HIV-1 viremia (Blips) and drug resistance in patients receiving HAART.

Tara L. Kieffer, Joel E Gallant, Charles Flexner, 2005, JAMA.

Induction therapy with protease-inhibitors modifies the effect of nevirapine resistance on virologic response to nevirapine-based HAART in children.

W. Tsai, L. Kuhn, D. Persaud, 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Switching children previously exposed to nevirapine to nevirapine-based treatment after initial suppression with a protease-inhibitor-based regimen: long-term follow-up of a randomised, open-label trial.

W. Tsai, L. Morris, L. Kuhn, 2012, The Lancet. Infectious diseases.

Nevirapine Resistance and Breast-Milk HIV Transmission: Effects of Single and Extended-Dose Nevirapine Prophylaxis in Subtype C HIV-Infected Infants

R. Bollinger, S. Kulkarni, D. Persaud, 2009, PloS one.

Analyses of HIV-1 drug-resistance profiles among infected adolescents experiencing delayed antiretroviral treatment switch after initial nonsuppressive highly active antiretroviral therapy.

J. Lindsey, S. Ray, S. Spector, 2008, AIDS patient care and STDs.

Early archiving and predominance of nonnucleoside reverse transcriptase inhibitor-resistant HIV-1 among recently infected infants born in the United States.

S. Ray, M. Purswani, D. Persaud, 2007, The Journal of infectious diseases.

Characterization of HIV infection in cisgender men and transgender women who have sex with men receiving injectable cabotegravir for HIV prevention: HPTN 083.

C. Petropoulos, C. Hendrix, M. Marzinke, 2021, The Journal of infectious diseases.

International AIDS Society global scientific strategy: towards an HIV cure 2016

Richard Jefferys, David Margolis, Jintanat Ananworanich, 2016, Nature Medicine.

Characterization of Human Immunodeficiency Virus (HIV) Infections in Women Who Received Injectable Cabotegravir or Tenofovir Disoproxil Fumarate/Emtricitabine for HIV Prevention: HPTN 084.

S. Delany-Moretlwe, C. Petropoulos, J. Mellors, 2022, The Journal of infectious diseases.

Absence of detectable HIV-1 viremia after treatment cessation in an infant.

D. Richman, T. Chun, M. Piatak, 2013, The New England journal of medicine.

Assessing the Variability of Cell-Associated HIV DNA Quantification through a Multicenter Collaborative Study

C. Giaquinto, J. Huggett, S. Watters, 2022, Microbiology spectrum.

Nosocomial Malaria and Saline Flush

John M. Pisciotta, T. Perl, D. Persaud, 2005, Emerging infectious diseases.

Analysis of the optimal cut-point for HIV-p24 antigen testing to diagnose HIV infection in HIV-exposed children from resource-constrained settings.

P. Tamma, C. Thompson, D. Persaud, 2011, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Global HIV Antiretroviral Drug Resistance: A Perspective and Report of a National Institute of Allergy and Infectious Diseases Consultation.

M. Wainberg, D. Kuritzkes, D. Pillay, 2017, The Journal of infectious diseases.

Latent reservoirs for HIV-1.

R. Siliciano, J. Blankson, D. Persaud, 1999, Current opinion in infectious diseases.

Clinical validation of a quantitative HIV-1 DNA droplet digital PCR assay: Applications for detecting occult HIV-1 infection and monitoring cell-associated HIV-1 dynamics across different subtypes in HIV-1 prevention and cure trials.

Lilly Siems, D. Persaud, E. Nastouli, 2021, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Lilly Siems, D. Persaud, E. Nastouli, 2020, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Latency in Human Immunodeficiency Virus Type 1 Infection: No Easy Answers

R. Siliciano, Yan Zhou, D. Persaud, 2003, Journal of Virology.

Novel Criteria for Diagnosing Acute and Early HIV Infection in a Multi-National Study of Early Antiretroviral Therapy Initiation.

B. Chi, J. Ananworanich, K. Ruxrungtham, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Residual Human Immunodeficiency Virus Type 1 Viremia in Some Patients on Antiretroviral Therapy Is Dominated by a Small Number of Invariant Clones Rarely Found in Circulating CD4+ T Cells

Claus O. Wilke, Thomas C. Quinn, Tara L. Kieffer, 2006, Journal of Virology.

A Novel Assay Allows Genotyping of the Latent Reservoir for Human Immunodeficiency Virus Type 1 in the Resting CD4+ T Cells of Viremic Patients

Thomas C. Quinn, Yan Zhou, Tara L. Kieffer, 2005, Journal of Virology.

Genetic complexity in the replication-competent latent HIV reservoir increases with untreated infection duration in infected youth

T. Greenough, J. Joy, D. Persaud, 2019, AIDS.

Diversity of hepatitis C virus infection among HIV-infected people who inject drugs in India

D. Boon, S. Ray, D. Persaud, 2019, VirusDisease.

Distinct Cytokine and Chemokine Dysregulation in Hospitalized Children with Acute COVID-19 and Multisystem Inflammatory Syndrome with Similar Levels of Nasopharyngeal SARS-CoV-2 Shedding.

D. Persaud, H. Mostafa, Weiqiang Zhou, 2021, The Journal of infectious diseases.

Human Immunodeficiency Virus Type 1 DNA Decay Dynamics With Early, Long-term Virologic Control of Perinatal Infection

S. Spector, E. Barr, S. Nichols, 2017, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Identification of Ongoing Human Immunodeficiency Virus Type 1 (HIV-1) Replication in Residual Viremia during Recombinant HIV-1 Poxvirus Immunizations in Patients with Clinically Undetectable Viral Loads on Durable Suppressive Highly Active Antiretroviral Therapy

T. Greenough, S. Ray, D. Persaud, 2009, Journal of Virology.

Slow human immunodeficiency virus type 1 evolution in viral reservoirs in infants treated with effective antiretroviral therapy.

S. Gange, T. Quinn, J. Casazza, 2007, AIDS research and human retroviruses.

Persistence of Wild-Type Virus and Lack of Temporal Structure in the Latent Reservoir for Human Immunodeficiency Virus Type 1 in Pediatric Patients with Extensive Antiretroviral Exposure

Thomas C. Quinn, Roxann Ashworth, Robert F. Siliciano, 2002, Journal of Virology.

Viremic relapse after HIV-1 remission in a perinatally infected child.

Katherine Luzuriaga, Kaitlin Rainwater-Lovett, J. Mellors, 2015, The New England journal of medicine.

Infants Receiving Very Early ART Have High CD4 Counts in the First Year of Life.

S. Spector, M. Cotton, D. Persaud, 2022, Clinical Infectious Diseases.

HIV type 1 (HIV-1) proviral reservoirs decay continuously under sustained virologic control in HIV-1-infected children who received early treatment.

D. Richman, B. Tabak, T. Chun, 2014, The Journal of infectious diseases.

Raltegravir Pharmacokinetics in Neonates Following Maternal Dosing

L. Mofenson, S. Spector, H. Teppler, 2014, Journal of acquired immune deficiency syndromes.

Delayed recognition of human immunodeficiency virus infection in preadolescent children.

W. Borkowsky, D. Persaud, S. Chandwani, 1992, Pediatrics.

Advances in Pediatric HIV-1 Cure Therapies and Reservoir Assays

D. Persaud, Adit Dhummakupt, Yufeng Liu, 2022, Viruses.

Quantitative Human Immunodeficiency Virus (HIV)-1 Antibodies Correlate With Plasma HIV-1 RNA and Cell-associated DNA Levels in Children on Antiretroviral Therapy.

E. Mick, D. Persaud, K. Luzuriaga, 2018, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Report from the First EPIICAL (Early-treated Perinatally HIV-infected Individuals: Improving Children's Actual Life with Novel Immunotherapeutic Strategies) General Assembly meeting, 9–11 November 2017, Rome, Italy

C. Giaquinto, P. Palma, J. Ananworanich, 2018, Journal of virus eradication.

Quantitative HIV-1 specific antibodies as predictors of peripheral blood cell-associated HIV-1 DNA concentrations.

D. Persaud, K. Luzuriaga, K. Patel, 2020, AIDS.

Paucity of Intact Non-Induced Provirus with Early, Long-Term Antiretroviral Therapy of Perinatal HIV Infection

D. Persaud, G. Siberry, S. Lamers, 2017, PloS one.

Treatment interruption after early-treated perinatal HIV-1 infection.

D. Persaud, K. Luzuriaga, 2016, AIDS.

Advances and hope for perinatal HIV remission and cure in children and adolescents

D. Persaud, K. Rainwater-Lovett, Priyanka Uprety, 2016, Current opinion in pediatrics.

Dynamics of the resting CD4+ T-cell latent HIV reservoir in infants initiating HAART less than 6 months of age

M. Hughes, D. Persaud, R. Yogev, 2012, AIDS.

Slower clearance of nevirapine resistant virus in infants failing extended nevirapine prophylaxis for prevention of mother-to-child HIV transmission.

S. Omer, D. Persaud, Y. Mengistu, 2011, AIDS research and human retroviruses.

Early nevirapine-based antiretroviral therapy for neonates at high risk for perinatal HIV infection: pharmacokinetics and safety data from a Phase I/II Proof of Concept Study

S. Spector, M. Cotton, D. Persaud, 2021 .

Pharmacokinetics and safety of early nevirapine-based antiretroviral therapy for neonates at high risk for perinatal HIV infection: a phase 1/2 proof of concept study.

S. Spector, D. Persaud, E. Capparelli, 2020, The lancet. HIV.

Cell-Associated HIV-1 DNA and RNA Decay Dynamics During Early Combination Antiretroviral Therapy in HIV-1-Infected Infants.

G. Yenokyan, D. Persaud, E. Capparelli, 2015, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Concordance between allele-specific PCR and ultra-deep pyrosequencing for the detection of HIV-1 non-nucleoside reverse transcriptase inhibitor resistance mutations.

L. Morris, L. Kuhn, D. Persaud, 2014, Journal of virological methods.

Alternative Sample Types for HIV-1 Antiretroviral Drug Resistance Testing.

Lilly Siems, D. Persaud, Dolly Singh, 2017, The Journal of infectious diseases.

Efficacy of primary chemoprophylaxis against Pneumocystis carinii pneumonia during the first year of life in infants infected with human immunodeficiency virus type 1.

W. Borkowsky, D. Persaud, H. Pollack, 1994, The Journal of pediatrics.

Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021

J. Nabukenya, T. Ndung’u, S. Lewin, 2021, Nature Medicine.

HIV-1 remission and possible cure in a woman after haplo-cord blood transplant

J. Mellors, D. Persaud, N. Tobin, 2023, Cell.

The Latent Human Immunodeficiency Virus (HIV) Reservoir Resides Primarily in CD32−CD4+ T Cells in Perinatally HIV-Infected Adolescents With Long-Term Virologic Suppression

Lilly Siems, D. Persaud, Dolly Singh, 2018, The Journal of infectious diseases.

Safety and immunogenicity of recombinant poxvirus HIV-1 vaccines in young adults on highly active antiretroviral therapy.

T. Greenough, P. Barker, D. Persaud, 2008, Vaccine.

How CD4+ T Cells Transcriptional Profile Is Affected by Culture Conditions: Towards the Design of Optimal In Vitro HIV Reactivation Assays

P. Palma, C. Cancrini, M. Lichterfeld, 2023, Biomedicines.

Differences in the induced latent HIV reservoir in perinatal and adult infection.

Lilly Siems, D. Persaud, R. B. Jones, 2020, JCI insight.

Inflammation and Immune Activation in Antiretroviral-Treated Human Immunodeficiency Virus Type 1-Infected African Infants and Rotavirus Vaccine Responses.

J. Lindsey, M. Levin, D. Persaud, 2017, Journal of Infectious Diseases.

Intestinal Integrity Biomarkers in Early Antiretroviral-Treated Perinatally HIV-1–Infected Infants

J. Lindsey, M. Levin, D. Persaud, 2018, The Journal of infectious diseases.

The microbiome and HIV persistence: implications for viral remission and cure

Lilly Siems, D. Persaud, W. L. Koay, 2018, Current opinion in HIV and AIDS.

Willingness of Racially Diverse Young Adults Living with HIV to Participate in HIV Cure Research: A Cross-Sectional Survey in the United States.

S. Deeks, D. Persaud, P. Saberi, 2022, AIDS research and human retroviruses.

HIV-1 remission and possible cure in a woman after haplo-cord blood transplant

J. Mellors, D. Persaud, N. Tobin, 2023, Cell.

Highlights of the Global HIV-1 CSF Escape Consortium Meeting, 9 June 2016, Bethesda, MD, USA

A. Winston, R. Swanstrom, R. Price, 2016, Journal of virus eradication.

Distinct Cytokine and Chemokine Dysregulation in Hospitalized Children With Acute Coronavirus Disease 2019 and Multisystem Inflammatory Syndrome With Similar Levels of Nasopharyngeal Severe Acute Respiratory Syndrome Coronavirus 2 Shedding

D. Persaud, H. Mostafa, Weiqiang Zhou, 2021, The Journal of infectious diseases.

Immune activation and exhaustion marker expression on T-cell subsets in ART-treated adolescents and young adults with perinatal HIV-1 infection as correlates of viral persistence

E. Boritz, D. Persaud, Weiqiang Zhou, 2023, Frontiers in Immunology.

Therapeutic vaccination expands and improves the function of the HIV-specific memory T-cell repertoire.

R. Gottardo, R. Koup, C. Andrews, 2013, The Journal of infectious diseases.

Effect of therapeutic HIV recombinant poxvirus vaccines on the size of the resting CD4+ T-cell latent HIV reservoir

T. Greenough, A. Blackford, D. Persaud, 2011, AIDS.

Markers of intestinal immune activation and inflammation are not associated with preterm birth among women with low level HIV viremia

K. Ghanem, D. Persaud, I. Burd, 2023, American journal of reproductive immunology.

Extended Analysis of HIV Infection in Cisgender Men and Transgender Women Who Have Sex with Men Receiving Injectable Cabotegravir for HIV Prevention: HPTN 083

J. Mellors, C. Hendrix, M. Marzinke, 2023, Antimicrobial agents and chemotherapy.

Research into a functional cure for HIV in neonates: the need for ethical foresight.

Seema K. Shah, C. Grady, D. Wendler, 2014, The Lancet. Infectious diseases.

Research on very early ART in neonates at risk of HIV infection.

Seema K. Shah, C. Grady, D. Wendler, 2014, The Lancet. Infectious diseases.

Current HIV/SIV Reservoir Assays for Preclinical and Clinical Applications: Recommendations from the Experts 2022 NIAID Workshop Summary.

Brigitte E. Sanders-Beer, R. Siliciano, J. Karn, 2023, AIDS research and human retroviruses.

Latent HIV-1 reservoirs in children: considerations for therapy

D. Persaud, 2006, Current opinion in HIV and AIDS.

Soluble CD14: An Independent Biomarker for the Risk of Mother-to-Child Transmission of HIV in a Setting of Preexposure and Postexposure Antiretroviral Prophylaxis.

R. Bollinger, R. Shivakoti, D. Persaud, 2016, The Journal of infectious diseases.

Insights from Clonal Expansion and HIV Persistence in Perinatal Infections

D. Persaud, Adit Dhummakupt, 2021, mBio.

Capitalizing on Postexposure Antiretroviral Prophylaxis to Restrict Seeding of the Human Immunodeficiency Virus Reservoir

D. Persaud, Adit Dhummakupt, 2020, Clinical Infectious Diseases.

Inflammation and Immune Activation in Antiretroviral-Treated Human Immunodeficiency Virus Type 1–Infected African Infants and Rotavirus Vaccine Responses

J. Lindsey, M. Levin, D. Persaud, 2017, The Journal of infectious diseases.

Varicella does not appear to be a cofactor for human immunodeficiency virus infection in children.

W. Borkowsky, D. Persaud, J. Oleske, 1992, The Pediatric Infectious Disease Journal.

Genotypic resistance in HIV-1-infected patients with persistently detectable low-level viremia while receiving highly active antiretroviral therapy.

Tara L. Kieffer, Richard D Moore, R. Siliciano, 2004, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

A sensitive genotyping assay for detection of drug resistance mutations in reverse transcriptase of HIV-1 subtypes B and C in samples stored as dried blood spots or frozen RNA extracts.

S. Ray, W. Moss, D. Persaud, 2006, Journal of virological methods.

Risk of AIDS increases in children aged 2 years and older with CD4 T cell percentage less than 15

W. Moss, D. Persaud, 2004 .

Erratum to: Experience and Outcomes of Breastfed Infants of Women Living with HIV in the United States: Findings from a Single Center Breastfeeding Support Initiative.

D. Persaud, Jean R. Anderson, W. Golden, 2022, Journal of the Pediatric Infectious Diseases Society.

Drug risk factors associated with a sustained outbreak of Clostridium difficile diarrhea in a teaching hospital.

D. Persaud, C. Rotstein, J. Thornley, 1994, The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses.

Capitalizing on Post-exposure ARV Prophylaxis to Restrict Seeding of the HIV Reservoir.

D. Persaud, Adit Dhummakupt, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Treatment interruption after early-treated perinatal HIV-1 infection.

D. Persaud, K. Luzuriaga, 2016, AIDS.

Research into a functional cure for HIV in neonates: the need for ethical foresight.

Seema K. Shah, C. Grady, D. Wendler, 2014, The Lancet. Infectious diseases.

Capitalizing on Postexposure Antiretroviral Prophylaxis to Restrict Seeding of the Human Immunodeficiency Virus Reservoir

D. Persaud, Adit Dhummakupt, 2021 .

W. Tsai, L. Morris, L. Kuhn, 2012, The Lancet. Infectious diseases.