G. Maertens

发表

HIV-1 Integrase Forms Stable Tetramers and Associates with LEDGF/p75 Protein in Human Cells*

Zeger Debyser, Yves Engelborghs, Bart Devreese, 2003, The Journal of Biological Chemistry.

A tripartite DNA-binding element, comprised of the nuclear localization signal and two AT-hook motifs, mediates the association of LEDGF/p75 with chromatin in vivo

A. Engelman, P. Cherepanov, G. Maertens, 2006, Nucleic acids research.

Measuring protein‐protein interactions inside living cells using single color fluorescence correlation spectroscopy. Application to human immunodeficiency virus type 1 integrase and LEDGF/p75

J. Vercammen, Z. Debyser, Y. Engelborghs, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Dimerization of Matrix Protein Is Required for Budding of Respiratory Syncytial Virus

P. Farrell, G. Maertens, A. Förster, 2015, Journal of Virology.

Key determinants of target DNA recognition by retroviral intasomes

A. Engelman, Erik Serrao, P. Cherepanov, 2015, Retrovirology.

Integrase residues that determine nucleotide preferences at sites of HIV-1 integration: implications for the mechanism of target DNA binding

Goedele N. Maertens, A. Engelman, Erik Serrao, 2014, Nucleic acids research.

B′-protein phosphatase 2A is a functional binding partner of delta-retroviral integrase

G. Maertens, 2015, Nucleic acids research.

Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ

V. E. Pye, P. Cherepanov, G. Maertens, 2020, Nature Communications.

Cabotegravir, the Long-Acting Integrase Strand Transfer Inhibitor, Potently Inhibits Human T-Cell Lymphotropic Virus Type 1 Transmission in vitro

G. Maertens, M. Barski, Bethany S. Schneiderman, 2022, Frontiers in Medicine.

Several Distinct Polycomb Complexes Regulate and Co-Localize on the INK4a Tumor Suppressor Locus

G. Peters, T. Racek, G. Maertens, 2009, PloS one.

Identification and Characterization of a Functional Nuclear Localization Signal in the HIV-1 Integrase Interactor LEDGF/p75*

A. Engelman, P. Cherepanov, Z. Debyser, 2004, Journal of Biological Chemistry.

USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation

A. Snijders, G. Maertens, Anna Stockum, 2018, PloS one.

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS.

G. Peters, Ming-Ming Zhou, M. Barradas, 2009, Genes & development.

Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor

G. Peters, S. Elderkin, G. Maertens, 2010, The EMBO journal.

Role for the MOV10 RNA helicase in Polycomb-mediated repression of the INK4a tumor suppressor

G. Peters, E. Bernstein, S. Brookes, 2010, Nature Structural &Molecular Biology.

PP2A Phosphatase as an Emerging Viral Host Factor

G. Maertens, M. Barski, J. J. Minnell, 2021, Frontiers in Cellular and Infection Microbiology.

Key determinants of target DNA recognition by retroviral intasomes

A. Engelman, Erik Serrao, P. Cherepanov, 2015, Retrovirology.

Structure and function of retroviral integrase

A. Engelman, P. Cherepanov, G. Maertens, 2021, Nature Reviews Microbiology.

LEDGF/p75 Is Essential for Nuclear and Chromosomal Targeting of HIV-1 Integrase in Human Cells*

E. De Clercq, P. Cherepanov, Z. Debyser, 2003, Journal of Biological Chemistry.

A phosphorylated form of Mel-18 targets the Ring1B histone H2A ubiquitin ligase to chromatin.

N. Brockdorff, G. Peters, S. Elderkin, 2007, Molecular cell.

Structure and function of retroviral integrase

A. Engelman, P. Cherepanov, G. Maertens, 2021, Nature Reviews Microbiology.

Retroviruses integrate into a shared, non-palindromic DNA motif

Paul D. W. Kirk, G. Maertens, M. Huvet, 2016, Nature Microbiology.

Bromo- and Extraterminal Domain Chromatin Regulators Serve as Cofactors for Murine Leukemia Virus Integration

A. Schambach, T. Schulz, P. Cherepanov, 2013, Journal of Virology.

3′-Processing and strand transfer catalysed by retroviral integrase in crystallo

P. Cherepanov, G. Maertens, S. Hare, 2012, The EMBO journal.

The mechanism of retroviral integration through X-ray structures of its key intermediates

Goedele N. Maertens, P. Cherepanov, G. Maertens, 2010, Nature.

Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75

A. Engelman, G. Wagner, P. Cherepanov, 2005, Nature Structural &Molecular Biology.

Inhibition of HTLV-1 Infection by HIV-1 First- and Second-Generation Integrase Strand Transfer Inhibitors

G. Maertens, M. Barski, J. J. Minnell, 2019, Front. Microbiol..

Structural basis for nuclear import of splicing factors by human Transportin 3

A. Engelman, N. Cook, A. Fassati, 2014, Proceedings of the National Academy of Sciences.

Retroviruses integrate into a shared, non-palindromic motif

Paul D. W. Kirk, G. Maertens, M. Huvet, 2015, bioRxiv.

Structural insights into the retroviral DNA integration apparatus.

P. Cherepanov, G. Maertens, S. Hare, 2011, Current opinion in structural biology.

DNA-induced Polymerization of HIV-1 Integrase Analyzed with Fluorescence Fluctuation Spectroscopy*

Jo Vercammen, Zeger Debyser, Yves Engelborghs, 2002, The Journal of Biological Chemistry.

Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures

S. Hughes, V. E. Pye, P. Cherepanov, 2021, Nature Communications.

Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor

G. Peters, S. Elderkin, G. Maertens, 2010, The EMBO journal.

Transcriptional co-activator p75 binds and tethers the Myc-interacting protein JPO2 to chromatin

A. Engelman, P. Cherepanov, G. Maertens, 2006, Journal of Cell Science.

Structural basis for nuclear import of splicing factors by human Transportin 3

A. Engelman, N. Cook, A. Fassati, 2014, Proceedings of the National Academy of Sciences.

The Thr205 Phosphorylation Site within Respiratory Syncytial Virus Matrix (M) Protein Modulates M Oligomerization and Virus Production

R. Tripp, D. Jans, E. Bacharach, 2014, Journal of Virology.

Virus–Host Interactions in Retrovirus Integration

A. Engelman, G. Maertens, 2018 .

Cell Culture Evaluation Hints Widely Available HIV Drugs Are Primed for Success if Repurposed for HTLV-1 Prevention

G. Maertens, Mphatso D. Kalemera, Allison K. Maher, 2024, Pharmaceuticals.