P. Wardman

发表

Kinetics of the reactions of nitrogen dioxide with glutathione, cysteine, and uric acid at physiological pH.

E. Ford, M. N. Hughes, P. Wardman, 2002, Free radical biology & medicine.

Cellular uptake of misonidazole and analogues with acidic or basic functions.

M. Stratford, P. Wardman, M. F. Dennis, 1985, International journal of radiation biology and related studies in physics, chemistry, and medicine.

Synthesis and fluorescence of N-substituted-1,8-naphthalimides

E. Clarke, P. Wardman, R. Middleton, 1986 .

Electron paramagnetic resonance spin trapping investigation into the kinetics of glutathione oxidation by the superoxide radical: re-evaluation of the rate constant.

P. Wardman, Claire M. Jones, A. Lawrence, 2002, Free radical biology & medicine.

Reduction Potentials of One-Electron Couples Involving Free Radicals in Aqueous Solution

P. Wardman, Peter Wardman, 1989 .

Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest.

L. Folkes, M. Trujillo, R. Radi, 2011, Free radical biology & medicine.

Formation of hydroxyl radicals on reaction of hypochlorous acid with ferrocyanide, a model iron(II) complex.

M. Stratford, P. Wardman, L. P. Candeias, 1994, Free radical research.

Free hydroxyl radicals are formed on reaction between the neutrophil‐derived species Superoxide anion and hypochlorous acid

M. Stratford, P. Wardman, L. P. Candeias, 1993, FEBS letters.

Calculation of Standard Reduction Potentials of Amino Acid Radicals and the Effects of Water and Incorporation into Peptides.

P. Wardman, D. M. Close, D. Close, 2018, The journal of physical chemistry. A.

The spontaneous and enzymatic reaction of N-acetyl-p-benzoquinonimine with glutathione: a stopped-flow kinetic study.

P. Wardman, B. Ketterer, S. Nelson, 1988, Archives of biochemistry and biophysics.

Pushing the frontiers of radiobiology: a sPecial feature in memory of sir oliver scott and Professor Jack fowler: review article nitroimidazoles as hypoxic cell radiosensitizers and hypoxia probes: misonidazole, myths and mistakes

P. Wardman, Jack Fowler, 2018 .

Oxidative metabolism of combretastatin A-1 produces quinone intermediates with the potential to bind to nucleophiles and to enhance oxidative stress via free radicals.

M. Stratford, L. Folkes, E. Madej, 2007, Chemical research in toxicology.

Bioreductive activation of quinones: redox properties and thiol reactivity.

P. Wardman, 1990, Free radical research communications.

Reactivity of thiols towards derivatives of 2- and 6-methyl-1,4-naphthoquinone bioreductive alkylating agents.

I. Wilson, A. Sartorelli, P. Wardman, 1987, Chemico-biological interactions.

Measurement of tumor oxygenation: a comparison between polarographic needle electrodes and a time-resolved luminescence-based optical sensor.

B. Vojnovic, P. Wardman, D. Chaplin, 1997, Radiation research.

Oxidative activation of indole-3-acetic acids to cytotoxic species- a potential new role for plant auxins in cancer therapy.

L. Folkes, P. Wardman, 2001, Biochemical pharmacology.

Nitric oxide in biological fluids: analysis of nitrite and nitrate by high-performance ion chromatography.

M. Stratford, G. Tozer, P. Wardman, 1995, Journal of chromatography. A.

Trans-fatty acids and radical stress: what are the real culprits?

P. Wardman, C. Chatgilialoglu, C. Ferreri, 2006, Bioorganic & medicinal chemistry.

Nitroakridin 3582: a fluorescent nitroacridine stain for identifying hypoxic cells.

A. Begg, N. J. McNally, P. Wardman, 1983, The British journal of radiology.

Properties of the radical intermediate obtained on oxidation of 2',7'-dichlorodihydrofluorescein, a probe for oxidative stress.

P. Wardman, M. Wrona, 2006, Free radical biology & medicine.

Standard electrode potentials involving radicals in aqueous solution: inorganic radicals

W. Koppenol, G. Merényi, P. Wardman, 2013 .

Evidence for the Role of a Peroxidase Compound I-type Intermediate in the Oxidation of Glutathione, NADH, Ascorbate, and Dichlorofluorescin by Cytochrome c/H2O2

P. Wardman, Peter Wardman, Claire M. Jones, 2003, Journal of Biological Chemistry.

The roles of thiol-derived radicals in the use of 2',7'-dichlorodihydrofluorescein as a probe for oxidative stress.

P. Wardman, K. Patel, M. Wrona, 2008, Free radical biology & medicine.

Reactivity of 2',7'-dichlorodihydrofluorescein and dihydrorhodamine 123 and their oxidized forms toward carbonate, nitrogen dioxide, and hydroxyl radicals.

P. Wardman, K. Patel, M. Wrona, 2005, Free radical biology & medicine.

Enhancing the efficacy of photodynamic cancer therapy by radicals from plant auxin (indole-3-acetic acid).

L. Folkes, P. Wardman, 2003, Cancer research.

Hypoxia-driven elimination of thiopurines from their nitrobenzyl prodrugs.

M. Stratford, P. Wardman, M. Naylor, 2007, Bioorganic & medicinal chemistry letters.

Radiolysis Studies of Oxidation and Nitration of Tyrosine and Some Other Biological Targets by Peroxynitrite-Derived Radicals

L. Folkes, M. Trujillo, R. Radi, 2022, International journal of molecular sciences.

Reaction of the carbonate radical with the spin-trap 5,5-dimethyl-1-pyrroline-N-oxide in chemical and cellular systems: pulse radiolysis, electron paramagnetic resonance, and kinetic-competition studies.

M. N. Álvarez, L. Folkes, R. Radi, 2007, Free radical biology & medicine.

The one-electron reduction potential of 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine): a hypoxia-selective bioreductive drug.

P. Wardman, K. Priyadarsini, M. Tracy, 1996, Free radical research.

"Radiation chemistry" literature compilations: their wider value in free radical research.

P. Wardman, A. Ross, 1991, Free radical biology & medicine.

The reduction potential of benzyl viologen: an important reference compound for oxidant/radical redox couples.

P. Wardman, 1991, Free radical research communications.

Weiss lecture. Radiation chemistry: basic, strategic or tactical science?

P. Wardman, 1989, International journal of radiation biology.

Halogenated indole-3-acetic acids as oxidatively activated prodrugs with potential for targeted cancer therapy.

L. Folkes, P. Wardman, S. Rossiter, 2002, Bioorganic & medicinal chemistry letters.

5-Fluoroindole-3-acetic acid: a prodrug activated by a peroxidase with potential for use in targeted cancer therapy.

M. Stratford, L. Folkes, P. Wardman, 2002, Biochemical pharmacology.

Indole-3-acetic acids and horseradish peroxidase: a new prodrug/enzyme combination for targeted cancer therapy.

P. Wardman, 2002, Current pharmaceutical design.

Horseradish peroxidase-mediated gene therapy: choice of prodrugs in oxic and anoxic tumor conditions.

C. Kanthou, G. Tozer, L. Folkes, 2001, Molecular cancer therapeutics.

Electron transfer and oxidative stress as key factors in the design of drugs selectively active in hypoxia.

P. Wardman, 2001, Current medicinal chemistry.

Kinetics of oxidation of tyrosine by a model alkoxyl radical

L. Folkes, M. Trujillo, R. Radi, 2012, Free radical research.

Kinetics of reduction of tyrosine phenoxyl radicals by glutathione.

L. Folkes, M. Trujillo, R. Radi, 2011, Archives of biochemistry and biophysics.

Interaction of dGMP radical with cysteamine and promethazine as possible model of DNA repair

R. Willson, P. Wardman, K. Asmus, 1974, Nature.

Application of pulse radiolysis methods to study the reactions and structure of biomolecules

P. Wardman, 1978 .

1,3,4(2H)‐isoquinolinetrione herbicides: Novel redox mediators of photosystem I

S. M. Ridley, G. Mitchell, E. Clarke, 1995 .

Free radical intermediates in the oxidation of flavone-8-acetic acid: possible involvement in its antitumour activity.

P. Wardman, L. P. Candeias, S. Everett, 1993, Free radical biology & medicine.

Kinetics of reaction of nitrogen dioxide with dihydrorhodamine and the reaction of the dihydrorhodamine radical with oxygen: implications for quantifying peroxynitrite formation in cells.

L. Folkes, P. Wardman, K. Patel, 2009, Archives of biochemistry and biophysics.

Methods to measure the reactivity of peroxynitrite-derived oxidants toward reduced fluoresceins and rhodamines.

P. Wardman, 2008, Methods in enzymology.

Peroxynitrite-derived carbonate and nitrogen dioxide radicals readily react with lipoic and dihydrolipoic acid.

L. Folkes, M. Trujillo, R. Radi, 2005, Free radical biology & medicine.

Kinetics and mechanisms of hypochlorous acid reactions.

L. Folkes, P. Wardman, L. P. Candeias, 1995, Archives of biochemistry and biophysics.

The Reaction of Superoxide Radicals withS-Nitrosoglutathione and the Products of Its Reductive Heterolysis*

E. Ford, M. N. Hughes, P. Wardman, 2002, The Journal of Biological Chemistry.

Use of the Dichlorofluorescein Assay to Measure “Reactive Oxygen Species”

P. Wardman, 2008, Radiation research.

Thiyl radicals react with nitric oxide to form S-nitrosothiols with rate constants near the diffusion-controlled limit.

L. Folkes, E. Madej, P. Wardman, 2008, Free radical biology & medicine.

Kinetic factors that control the fate of thiyl radicals in cells.

P. Wardman, C. Sonntag, C. von Sonntag, 1995, Methods in enzymology.

Reductive role of glutathione in the redox cycling of oxidizable drugs.

G. Cohen, P. Wardman, I. Wilson, 1986, Biochemical pharmacology.

Some reactions and properties of nitro radical-anions important in biology and medicine.

P. Wardman, 1985, Environmental health perspectives.

Increase in intracellular cysteine after exposure to dithiothreitol: implications in radiobiology.

M. Stratford, P. Wardman, M. F. Dennis, 1989, International journal of radiation biology.

The effects of nitric oxide or oxygen on the stable products formed from the tyrosine phenoxyl radical

L. Folkes, M. Trujillo, R. Radi, 2021, Free radical research.

Free Radical Intermediates in the Reduction of Quinoxaline N-Oxide Antitumor Drugs: Redox and Prototropic Reactions

P. Wardman, M. Naylor, K. Priyadarsini, 1996 .

Kinetics of superoxide scavenging by glutathione: an evaluation of its role in the removal of mitochondrial superoxide.

C. M. Jones, P. Wardman, A. Lawrence, 2003, Biochemical Society transactions.

Electrons in liquid alcohols at low temperatures

P. Wardman, J. Baxendale, 1973 .

Toxicity of nitro compounds toward hypoxic mammalian cells in vitro: dependence on reduction potential.

G. Adams, I. Stratford, P. Wardman, 1980, Journal of the National Cancer Institute.

Mammalian cell toxicity of nitro compounds : dependence upon reduction potential.

E. Clarke, G. Adams, I. Stratford, 1976, Biochemical and biophysical research communications.

The influence of cell walls from host and non-host plants on the production and activity of polygalacturonide-degrading enzymes from fungal pathogens

P. Wardman, R. Cooper, James Skelton, 1981 .

Radiosensitization by Nitric Oxide at Low Radiation Doses

K. Rothkamm, L. Folkes, P. Wardman, 2007, Radiation research.

The uptake of the radiosensitizing compound Ro 03-8799 (Pimonidazole) in human tumors.

S. Dische, M. Stratford, P. Wardman, 1989, International journal of radiation oncology, biology, physics.

Heats of ionization of HO2 and OH in aqueous solution

P. Wardman, J. Baxendale, M. Ward, 1971 .

The measurement of hypoxia in tumours.

P. Wardman, R. Hodgkiss, 1992, BJR supplement.

Synthesis and biological properties of bioreductively targeted nitrothienyl prodrugs of combretastatin A-4

M. Stratford, P. Wardman, M. Naylor, 2006, Molecular Cancer Therapeutics.

Bioreductively-activated prodrugs for targeting hypoxic tissues: elimination of aspirin from 2-nitroimidazole derivatives.

M. Stratford, P. Wardman, M. Naylor, 1999, Bioorganic & medicinal chemistry letters.

Sunscreens inadequately protect against ultraviolet-A-induced free radicals in skin: implications for skin aging and melanoma?

P. Wardman, R. Sanders, C. Linge, 2003, The Journal of investigative dermatology.

Influence of plasma glutathione levels on radiation mucositis.

P. Hoskin, S. Bentzen, M. Stratford, 2001, International journal of radiation oncology, biology, physics.

Synthesis and properties of prodrugs activated in hypoxia to give bleomycin analogues.

P. Wardman, L. P. Candeias, J. Parrick, 1998, Bioorganic & medicinal chemistry letters.

Advances in Brief Enhancing the Efficacy of Photodynamic Cancer Therapy by Radicals from Plant Auxin ( Indole-3-Acetic Acid ) 1

L. Folkes, P. Wardman, 2003 .

[5] Perthiols as antioxidants: Radical-scavenging andprooxidative mechanisms

P. Wardman, S. Everett, 1995 .

Preparative, physico-chemical and cytotoxicity studies of prodrugs activated in hypoxia to give metal-binding analogues of bleomycin

P. Wardman, L. P. Candeias, J. Parrick, 1999 .

Uptake and cytotoxicity of novel nitroimidazole-polyamine conjugates in Ehrlich ascites tumour cells.

P. Cullis, G. Cohen, P. Wardman, 1992, Biochemical pharmacology.

The use of nitroaromatic compounds as hypoxic cell radiosensitizers.

P. Wardman, 1977, Current topics in radiation research quarterly.

Rates of reaction of indoleacetic acids with horseradish peroxidase compound I and their dependence on the redox potentials.

L. Folkes, P. Wardman, L. P. Candeias, 1996, Biochemistry.

Fluorescent markers for hypoxic cells. A study of novel heterocyclic compounds that undergo bio-reductive binding.

G. Wilson, A. Begg, M. Stratford, 1991, Biochemical pharmacology.

Fluorescent Probes for Hypoxia: Chemical Aspects

P. Wardman, R. Middleton, J. Parrick, 1990 .

The rationale for the development of improved hypoxic cell radiosensitizers.

E. Clarke, P. Wardman, R. Wallace, 1978, The British journal of cancer. Supplement.

Peroxidase-catalyzed effects of indole-3-acetic acid and analogues on lipid membranes, DNA, and mammalian cells in vitro.

M. Stratford, L. Folkes, P. Wardman, 1999, Biochemical pharmacology.

The reaction of oxygen with radicals from oxidation of tryptophan and indole-3-acetic acid.

R. Mason, P. Wardman, L. P. Candeias, 1997, Biophysical chemistry.

Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish peroxidase/indole-3-acetic acid

G. Tozer, L. Folkes, P. Wardman, 2000, Cancer Gene Therapy.

Enhancement of peroxidase-induced lipid peroxidation by indole-3-acetic acid: effect of antioxidants.

L. Folkes, P. Wardman, L. P. Candeias, 1996, Redox report : communications in free radical research.

Enhancement of lipid peroxidation by indole-3-acetic acid and derivatives: substituent effects.

L. Folkes, P. Wardman, L. P. Candeias, 1995, Free radical research.

Electron-affinic sensitization. VII. A correlation between structures, one-electron reduction potentials, and efficiencies of nitroimidazoles as hypoxic cell radiosensitizers.

G. Adams, I. Stratford, P. Wardman, 1976, Radiation research.

Observations on solvated electrons in aliphatic hydrocarbons at room temperature by pulse radiolysis

P. Wardman, J. Baxendale, C. Bell, 1973 .

The decay of solvated electrons in irradiated liquid alcohols

P. Wardman, J. Baxendale, 1984 .

Indolequinone antitumor agents: reductive activation and elimination from (5-methoxy-1-methyl-4,7-dioxoindol-3-yl)methyl derivatives and hypoxia-selective cytotoxicity in vitro.

G. Adams, I. Stratford, M. Stratford, 1998, Journal of medicinal chemistry.

Modifying rates of reductive elimination of leaving groups from indolequinone prodrugs: a key factor in controlling hypoxia-selective drug release.

B. Vojnovic, M. Stratford, P. Wardman, 2002, Biochemical pharmacology.

Free radical mechanisms in anti-cancer drug research

P. Wardman, 2001 .

Controlling the rates of reductively-activated elimination from the (indol-3-yl)methyl position of indolequinones

B. Vojnovic, M. Stratford, P. Wardman, 2001 .

Rates of reductive elimination of substituted nitrophenols from the (indol-3-yl)methyl position of indolequinones

B. Vojnovic, M. Stratford, P. Wardman, 2001 .

Prodrugs for targeting hypoxic tissues: regiospecific elimination of aspirin from reduced indolequinones.

I. Stratford, M. Stratford, M. Jaffar, 1999, Bioorganic & medicinal chemistry letters.

Fluorescent and luminescent probes for measurement of oxidative and nitrosative species in cells and tissues: progress, pitfalls, and prospects.

P. Wardman, Peter Wardman, 2007, Free radical biology & medicine.

Bioreductive fluorescent markers for hypoxic cells: a study of 2-nitroimidazoles with 1-substituents containing fluorescent, bridgehead-nitrogen, bicyclic systems.

G. Wilson, P. Wardman, R. Middleton, 1992, Journal of medicinal chemistry.

Oxidative denitrification of the antitumour drug hydroxyguanidine.

M. Stratford, K. Smith, P. Wardman, 1998, Free radical biology & medicine.

Pulse radiolysis and cyclic voltammetry studies of redox properties of phenothiazine radicals

E. Madej, P. Wardman, 2006 .

Mechanism of tryptophan oxidation by some inorganic radical-anions: a pulse radiolysis study

G. Adams, P. Wardman, R. Cundall, 1976 .

One-electron reduction of 2- and 6-methyl-1,4-naphthoquinone bioreductive alkylating agents.

A. Sartorelli, P. Wardman, T. Lin, 1986, Journal of medicinal chemistry.

Selectivity of effects of redox-active cobalt(III) complexes on tumor tissue.

P. Wardman, L. Campanella, L. Bubnovskaya, 2004, Experimental oncology.

Electron-Affinic SensitizationVII. A Correlation between Structures, One-Electron Reduction Potentials, and Efficiencies of Nitroimidazoles as Hypoxic Cell Radiosensitizers

G. Adams, I. Stratford, P. Wardman, 2012 .

Free radicals in biology: the pulse radiolysis approach

G. Adams, P. Wardman, 1977 .

ELECTRON SPIN RESONANCE STUDIES OF THE RADIOLYSIS OF ALIPHATIC AMINES ADSORBED ON SILICA GEL.

P. Wardman, D. Smith, 1971 .

Indolequinone bioreductive drugs: kinetic factors which influence selectivity for hypoxia.

P. Wardman, M. Naylor, K. Patel, 1998, Anti-cancer drug design.

Oxidation of tetrahydrobiopterin by biological radicals and scavenging of the trihydrobiopterin radical by ascorbate.

M. Stratford, P. Wardman, K. Patel, 2002, Free radical biology & medicine.

Rates of Reductive Elimination of Substituted Nitrophenols from the (Indol-3-yl)methyl Position of Indolequinones (I)—(III).

B. Vojnovic, M. Stratford, P. Wardman, 2001 .

Hypoxia-selective antitumor agents. 15. Modification of rate of nitroreduction and extent of lysosomal uptake by polysubstitution of 4-(alkylamino)-5-nitroquinoline bioreductive drugs.

W. Denny, W. Wilson, P. Wardman, 1997, Journal of medicinal chemistry.

Redox-active cobalt complexes as promising antitumor agents

P. Wardman, L. Campanella, L. Bubnovskaya, 2003 .

Synthesis, hydroxyl radical production and cytotoxicity of analogues of bleomycin.

P. Wardman, J. Parrick, L. Mehta, 2000, Bioorganic & Medicinal Chemistry.

Chemical properties of ‘radiation modifiers’ of DNA damage and their radiobiological effects

P. Wardman, 1991 .

The mechanism of radiosensitization by electron-affinic compounds

P. Wardman, 1987 .

Perthiols as antioxidants: radical-scavenging and prooxidative mechanisms.

P. Wardman, S. Everett, 1995, Methods in enzymology.

The radiation chemistry of liquid and glassy methanol

F. Dainton, P. Wardman, G. Salmon, 1969, Proceedings of the Royal Society of London. A. Mathematical and Physical Sciences.

Direct Observation of Solvation of the Electron in Liquid Alcohols by Pulse Radiolysis

P. Wardman, J. Baxendale, J. H. BAXENDALE, 1971, Nature.

Yields of excited singlet and triplet states of some aromatics in the pulse radiolysis of cyclohexane solutions

P. Wardman, J. Baxendale, 1971 .

Chapter 4 – SENSITIZATION AND PROTECTION OF OXIDATIVE DAMAGE CAUSED BY HIGH ENERGY RADIATION

P. Wardman, 1993 .

Radiation chemistry in the clinic: Hypoxic cell radiosensitizers for radiotherapy

P. Wardman, 1984 .

The oxidizing power of the glutathione thiyl radical as measured by its electrode potential at physiological pH.

E. Madej, P. Wardman, 2007, Archives of biochemistry and biophysics.

Free-radical repair by a novel perthiol: reversible hydrogen transfer and perthiyl radical formation.

L. Folkes, P. Wardman, K. Asmus, 1994, Free radical research.

Approaches to modeling chemical reaction pathways in radiobiology

P. Wardman, 2022, International journal of radiation biology.

Standard electrode potentials involving radicals in aqueous solution: inorganic radicals (IUPAC Technical Report)

Branko Ruscic, Robert E. Huie, W. Koppenol, 2015 .

Radicals from one-electron reduction of nitro compounds, aromatic N-oxides and quinones: the kinetic basis for hypoxia-selective, bioreductive drugs.

M. Stratford, P. Wardman, M. F. Dennis, 1995, Biochemical Society symposium.

Control of the generation and reactions of free radicals in biological systems by kinetic and thermodynamic factors.

P. Wardman, I. Wilson, 1987, Free radical research communications.

Peroxidase activation of 1-naphthol to naphthoxy or naphthoxy-derived radicals and their reaction with glutathione.

G. Cohen, P. Wardman, L. H. Patterson, 1986, Chemico-biological interactions.

ENHANCEMENT OF LIPID PEROXIDATION BY SUBSTITUENT EFFECTS INDOLE-3-ACETIC ACID AND DERIVATIVES:

L. Folkes, P. Wardman, L. P. Candeias, 1995 .

Chemical radiosensitizers for use in radiotherapy.

P. Wardman, P Wardman, 2007, Clinical oncology (Royal College of Radiologists (Great Britain)).

Enzymic cis-trans isomerization of nitrofuran derivatives: isomerizing activity of xanthine oxidase, lipoyl dehydrogenase, DT-diaphorase and liver microsomes.

S. Kitamura, P. Wardman, Y. Kato, 1979, Biochimica et biophysica acta.

Fenton chemistry: an introduction.

P. Wardman, L. P. Candeias, 1996, Radiation research.

Reactions of desferrioxamine with peroxynitrite-derived carbonate and nitrogen dioxide radicals.

L. Folkes, M. Trujillo, R. Radi, 2004, Free radical biology & medicine.

Radiation chemistry comes before radiation biology

P. Wardman, P. O'Neill, 2009, International journal of radiation biology.

Evaluation of the “radical sink” hypothesis from a chemical-kinetic viewpoint

P. Wardman, 1998 .

Electron-Transfer Reactions of Nitroaromatic Radical-Anions Observed by Pulse Radiolysis

E. Clarke, P. Wardman, 1979 .

Oxygen inhibition of nitroreductase: electron transfer from nitro radical-anions to oxygen.

E. Clarke, P. Wardman, 1976, Biochemical and biophysical research communications.

Fluorescent markers for hypoxic cells: a study of nitroaromatic compounds, with fluorescent heterocyclic side chains, that undergo bioreductive binding.

G. Wilson, M. Stratford, P. Wardman, 1991, Journal of medicinal chemistry.

Time as a Variable in Radiation Biology: The Oxygen Effect

P. Wardman, 2016, Radiation Research.

The importance of radiation chemistry to radiation and free radical biology (The 2008 Silvanus Thompson Memorial Lecture).

P. Wardman, 2009, The British journal of radiology.

Radiation chemistry applied to drug design.

P. Wardman, L. P. Candeias, S. Everett, 1994, International journal of radiation biology.

Prediction and Measurement of Redox Properties of Drugs and Biomolecules

P. Wardman, 1990 .

Nitroaryl compounds as potential fluorescent probes for hypoxia. I. Chemical criteria and constraints.

E. Clarke, M. Stratford, P. Wardman, 1984, International journal of radiation oncology, biology, physics.

Cis-trans isomerization of the (5-nitro-2-furyl)acrylamide, AF-2, initiated by ascorbate, glutathione, Fe(II) and OH-.

E. Clarke, P. Wardman, I. Wilson, 1984, Biochemical pharmacology.

Quantitative structure-activity relationships (QSARs): Principle and practice

P. Wardman, 1983 .

Reduction of nitroimidazoles in model chemical and biological systems.

E. Clarke, M. Stratford, P. Wardman, 1982, International journal of radiation oncology, biology, physics.

Anaerobic reduction of nitroimidazoles by reduced flavin mononucleotide and by xanthine oxidase.

E. Clarke, P. Wardman, K. H. Goulding, 1980, Biochemical pharmacology.

Are ortho-substituted 4-nitroimidazoles a new generation of radiation-induced arylating agents?

E. Clarke, P. Wardman, Eric D. Clarke, 1980, International journal of radiation biology and related studies in physics, chemistry, and medicine.

Structure-activity relationships in the development of hypoxic cell radiosensitizers. II. Cytotoxicity and therapeutic ratio.

E. Clarke, G. Adams, I. Stratford, 1979, International journal of radiation biology and related studies in physics, chemistry, and medicine.

One-electron reduction potentials of substituted nitroimidazoles measured by pulse radiolysis

E. Clarke, P. Wardman, 1976 .

Letter: Protonation of the radical-anions of nitro-imidazole radiosensitizers and the formation of radical-adducts.

P. Wardman, 1975, International journal of radiation biology and related studies in physics, chemistry, and medicine.

Reactivity of a Free Radical Probe with Erythrocyte Membranes

P. Wardman, R. Cundall, R. Bisby, 1975 .

Revisiting the interaction of the radical anion metabolite of nitrofurantoin with glutathione.

L. Folkes, R. Mason, P. Wardman, 2002, Archives of biochemistry and biophysics.

Nitroimidazoles as anaerobic electron acceptors for xanthine oxidase.

E. Clarke, P. Wardman, K. H. Goulding, 1982, Biochemical pharmacology.

Molecular Structure and Biological Activity of Hypoxic Cell Radiosensitizers and Hypoxic-Specific Cytotoxins

P. Wardman, 1982 .

Structure-activity relationships in the development of hypoxic cell radiosensitizers. I. Sensitization efficiency.

E. Clarke, G. Adams, I. Stratford, 1979, International journal of radiation biology and related studies in physics, chemistry, and medicine.

The nanosecond pulse radiolysis of solutions of biphenyl in isopentane at -120°C

P. Wardman, J. Baxendale, 1971 .

High-performance ion chromatography applied to free-radical mechanisms in drug design the problem of ion analysis at high ionic strengths

M. Stratford, P. Wardman, M. F. Dennis, 1997 .

Chemical properties which control selectivity and efficacy of aromatic N-oxide bioreductive drugs.

I. Stratford, M. Stratford, P. Wardman, 1996, The British journal of cancer. Supplement.

Molecular mechanisms for the hypoxia-dependent activation of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233).

A. Rauth, K. Laderoute, P. Wardman, 1988, Biochemical pharmacology.

Radiotherapy Using High-Intensity Pulsed Radiation Beams (FLASH): A Radiation-Chemical Perspective

P. Wardman, 2020, Radiation Research.

Nitroaryl compounds as potential fluorescent probes for hypoxia. II. Identification and properties of reductive metabolites.

E. Clarke, M. Stratford, P. Wardman, 1984, International journal of radiation oncology, biology, physics.

ONE‐ELECTRON REDUCTION POTENTIALS OF SUBSTITUTED NITROIMIDAZOLES MEASURED BY PULSE RADIOLYSIS

E. Clarke, P. Wardman, 1976 .

Radiosensitization by non-nitro compounds.

P. Wardman, R. Wallace, M. Watts, 1982, International journal of radiation oncology, biology, physics.

The kinetics of the reaction of 'anomalous' 4-nitroimidazole radiosensitizers with thiols.

P. Wardman, 1982, International journal of radiation biology and related studies in physics, chemistry, and medicine.

Electron transfer reactions in RB90745, a bioreductive drug having both aromatic N-oxide and nitroarene moieties.

M. Stratford, P. Wardman, M. Naylor, 1996, Free radical research.

Glutathione-reactive nitro compounds as radiosensitizers: mechanistic and therapeutic implications.

M. Stratford, P. Wardman, M. F. Dennis, 1986, International journal of radiation oncology, biology, physics.

Temperature effects on the one-electron reduction potentials of nitroaryl compounds.

E. Clarke, P. Wardman, 1991, Free radical research communications.

RADIOSENSITISING NITROIMIDAZOLE DRUGS: TRIPLET STATE ENERGY AND REACTIVITY

A. Parker, P. Wardman, T. J. Kemp, 1987 .

Structure-activity relationships in the development of hypoxic cell radiosensitizers. III. Effects of basic substituents in nitroimidazole sidechains.

E. Clarke, G. Adams, I. Stratford, 1980, International journal of radiation biology and related studies in physics, chemistry, and medicine.

Molecular mechanisms of oxygen and "electron-affinic" radiosensitizers.

P. Wardman, 1989, International journal of radiation oncology, biology, physics.

Calculations of the Energetics of Oxidation of Aqueous Nucleosides and the Effects of Prototropic Equilibria.

P. Wardman, D. M. Close, D. Close, 2016, The journal of physical chemistry. A.

Pitfalls in the Use of Common Luminescent Probes for Oxidative and Nitrosative Stress

B. Vojnovic, P. Wardman, Claire M. Jones, 2002, Journal of Fluorescence.

Cytochrome C is a potent catalyst of dichlorofluorescin oxidation: implications for the role of reactive oxygen species in apoptosis.

P. Wardman, M. Burkitt, 2001, Biochemical and biophysical research communications.

Pulse radiolysis observations of solvated electrons in liquid hydrocarbons

P. Wardman, J. Baxendale, C. Bell, 1971 .

Redox properties and rate constants in free-radical mediated damage.

E. Clarke, P. Wardman, 1987, The British journal of cancer. Supplement.

Toward targeted "oxidation therapy" of cancer: peroxidase-catalysed cytotoxicity of indole-3-acetic acids.

L. Folkes, P. Wardman, L. P. Candeias, 1998, International journal of radiation oncology, biology, physics.

Factors controlling the substrate specificity of peroxidases: kinetics and thermodynamics of the reaction of horseradish peroxidase compound I with phenols and indole-3-acetic acids.

L. Folkes, P. Wardman, L. P. Candeias, 1997, Biochemistry.

Selective Activation of Drugs by Redox Processes

G. Adams, P. Wardman, E. Fielden, 1990, NATO ASI Series.

A pulse radiolysis study of some free radical reactions with erythrocyte membranes.

P. Wardman, R. Cundall, R. Bisby, 1975, Biochimica et biophysica acta.

Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms

R. Mikkelsen, P. Wardman, Peter Wardman, 2003, Oncogene.

Measurement of oxygen tension in tumours by time-resolved fluorescence.

B Vojnovic, B. Vojnovic, P. Wardman, 1996, The British journal of cancer. Supplement.

A comparison of the tumour concentrations obtainable with misonidazole and Ro 03-8799.

S. Dische, M. Stratford, P. Wardman, 1986, The British journal of radiology.

Iminoxyl radicals and stable products from the one-electron oxidation of 1-methylindole-3-carbaldehyde oximes

B. Vojnovic, M. Stratford, E. Ford, 2001 .

Correlation of the radiosensitization potency afforded by nitroacridine intercalators with their electron scavenging efficiency in DNA.

P. B. Roberts, W. Denny, W. Wilson, 1992, International journal of radiation oncology, biology, physics.

1,3,4(2H)‐Isoquinolinetriones: evaluation of amino‐substituted derivatives as redox mediator herbicides

S. M. Ridley, G. Mitchell, E. Clarke, 2000 .

The radiolysis of methanol: product yields, rate constants, and spectroscopic parameters of intermediates

P. Wardman, J. Baxendale, 1975 .

Activation of cytochrome c to a peroxidase compound I-type intermediate by H2O2: relevance to redox signalling in apoptosis.

P. Wardman, Claire M. Jones, A. Lawrence, 2004, Biochemical Society symposium.

Oxidative denitrification of N omega-hydroxy-L-arginine by the superoxide radical anion.

M. Stratford, P. Wardman, M. F. Dennis, 1996, The Biochemical journal.

Comment on: May oxygen depletion explain the FLASH effect? A chemical track structure analysis.

P. Wardman, 2021, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Hypoxia in biology and medicine: the legacy of L H Gray.

P. Dendy, P. Wardman, 2006, The British journal of radiology.

Factors Important in the Use of Fluorescent or Luminescent Probes and Other Chemical Reagents to Measure Oxidative and Radical Stress

P. Wardman, 2023, Biomolecules.

Targeting radiosensitizers to DNA by minor groove binding: nitroarenes based on netropsin and distamycin

M. Stratford, P. Wardman, J. Parrick, 1993 .

Nitric oxide involvement in the toxicity of hydroxyguanidine in leukaemia HL60 cells.

M. Stratford, K. Smith, P. Wardman, 1996, The British journal of cancer. Supplement.

Free-Radical Intermediates and Stable Products in the Oxidation of Indole-3-acetic acid

M. Stratford, L. Folkes, P. Wardman, 1994 .

Radiotherapy Using High-Intensity Pulsed Radiation Beams (FLASH): A Radiation-Chemical Perspective.

P. Wardman, 2020, Radiation research.

Interaction of triplet-state nucleic acid bases with electroaffinic molecules in solution by laser flash photolysis

A. Parker, P. Wardman, T. J. Kemp, 1987 .

Interaction of Triplet-State Nucleic Acid Bases with Electroaffinic Molecules in Solution by Laser Flash Photolysis.

A. Parker, P. Wardman, T. J. Kemp, 1987 .

Kinetics of the reaction between nitric oxide and glutathione: implications for thiol depletion in cells.

L. Folkes, P. Wardman, 2004, Free radical biology & medicine.

Reaction of hydrated electrons with guanine derivatives: tautomerism of intermediate species.

P. Wardman, C. Chatgilialoglu, Q. G. Mulazzani, 2009, The journal of physical chemistry. B.

Selective Free Radical Reactions with Proteins and Enzymes: A Reversible Equilibrium in the Reaction of with Lysozyme

G. Adams, P. Wardman, R. Cundall, 1982 .

Biologically relevant small radicals

G. Bauer, B. Golding, P. Wardman, 2008 .

Initiating redox reactions by ionizing radiation: A versatile, selective and quantitative tool

P. Wardman, 2023, Redox Biochemistry and Chemistry.

The mechanism of the free-radical-induced chain isomerisation of 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide

E. Clarke, P. Wardman, K. Tatsumi, 1984 .