I. Reynolds

发表

Subcellular localization of glutamate-stimulated intracellular magnesium concentration changes in cultured rat forebrain neurons using confocal microscopy

C. Cheng, I. Reynolds, C. Cheng, 1999, Neuroscience.

Glutamate-induced increases in intracellular free Mg2+ in cultured cortical neurons

I. Reynolds, J. Brocard, S. Rajdev, 1993, Neuron.

Effects of Oxidants and Glutamate Receptor Activation on Mitochondrial Membrane Potential in Rat Forebrain Neurons

I. Reynolds, J. Scanlon, 1998, Journal of neurochemistry.

ΔΨm‐Dependent and ‐independent production of reactive oxygen species by rat brain mitochondria

Ian J. Reynolds, Tatyana V. Votyakova, I. Reynolds, 2001 .

Characterization of the Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 ADX88178 in Rodent Models of Neuropsychiatric Disorders

R. Duvoisin, J. Uslaner, J. Raber, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Mitochondrial Trafficking to Synapses in Cultured Primary Cortical Neurons

I. Reynolds, D. Chang, Anthony S. Honick, 2006, The Journal of Neuroscience.

Calcium-antagonist drugs. Receptor interactions that clarify therapeutic effects.

S. Snyder, I. Reynolds, S. Snyder, 1985 .

MitoTracker labeling in primary neuronal and astrocytic cultures: influence of mitochondrial membrane potential and oxidants

Ian J. Reynolds, Tatyana V. Votyakova, Jennifer F. Buckman, 2001, Journal of Neuroscience Methods.

Arcaine is a competitive antagonist of the polyamine site on the NMDA receptor.

I. Reynolds, 1990, European journal of pharmacology.

The Redox Biology of Excitotoxic Processes: The NMDA Receptor, TOPA Quinone, and the Oxidative Liberation of Intracellular Zinc

P. Rosenberg, I. Reynolds, E. Aizenman, 2020, Frontiers in Neuroscience.

Reduction of NMDA receptors with dithiothreitol increases [3H]‐MK‐801 binding and NMDA‐induced Ca2+ fluxes

I. Reynolds, E. Aizenman, E. Rush, 1990, British journal of pharmacology.

Glutamate-induced intracellular calcium changes and neurotoxicity in cortical neuronsin vitro: Effect of chemical ischemia

I. Reynolds, S. Rajdev, I.J Reynolds, 1994, Neuroscience.

Characterization of Hydrogen Peroxide Toxicity in Cultured Rat Forebrain Neurons

K. Hoyt, I. Reynolds, T. Hastings, 1997, Neurochemical Research.

Fluctuations in mitochondrial membrane potential in single isolated brain mitochondria: modulation by adenine nucleotides and Ca2+.

I. Reynolds, O. Vergun, 2004, Biophysical journal.

Spontaneous changes in mitochondrial membrane potential in single isolated brain mitochondria.

I. Reynolds, O. Vergun, T. Votyakova, 2003, Biophysical journal.

Mitochondrial Depolarization in Glutamate-Stimulated Neurons: An Early Signal Specific to Excitotoxin Exposure

I. Reynolds, R. White, RJ White, 1996, The Journal of Neuroscience.

Mitochondria accumulate Ca2+ following intense glutamate stimulation of cultured rat forebrain neurones.

I. Reynolds, R. White, 1997, The Journal of physiology.

The role of intracellular Na+ and mitochondria in buffering of kainate‐induced intracellular free Ca2+ changes in rat forebrain neurones

K. Hoyt, I. Reynolds, A. Stout, 1998, The Journal of physiology.

Glutamate mobilizes [Zn2+]i through Ca2+‐dependent reactive oxygen species accumulation

I. Reynolds, Jennifer Zeak, K. Dineley, 2008, Journal of neurochemistry.

Simultaneous detection of intracellular free calcium and zinc using fura-2FF and FluoZin-3.

M. Devinney, I. Reynolds, K. Dineley, 2005, Cell calcium.

Mitochondrial Membrane Potential and the Permeability Transition in Excitotoxicity

I. Reynolds, 1999, Annals of the New York Academy of Sciences.

New perspectives on mitochondrial morphology in cell function

I. Reynolds, J. Brocard, G. L. Rintoul, 2003, Biology of the cell.

Mitochondrial Trafficking in Neurons: A Key Variable in Neurodegeneration?

I. Reynolds, G. L. Rintoul, L. Malaiyandi, 2004, Journal of bioenergetics and biomembranes.

Loperamide: blockade of calcium channels as a mechanism for antidiarrheal effects.

S. Snyder, I. Reynolds, R. Gould, 1984, The Journal of pharmacology and experimental therapeutics.

Calcium Channel Blockade: Possible Explanation for Thioridazine's Peripheral Side Effects

S. Snyder, K. Murphy, I. Reynolds, 1984 .

(-)-[3H] desmethoxyverapamil labels multiple calcium channel modulator receptors in brain and skeletal muscle membranes: differentiation by temperature and dihydropyridines.

S. Snyder, A. Snowman, I. Reynolds, 1986, The Journal of pharmacology and experimental therapeutics.

Cytoplasmic metallothionein overexpression protects NIH 3T3 cells from tert-butyl hydroperoxide toxicity.

Simon C Watkins, J. Lazo, B. Pitt, 1994, The Journal of biological chemistry.

Effects of pyrroloquinoline quinone on glutamate-induced production of reactive oxygen species in neurons.

I. Reynolds, J. Scanlon, E. Aizenman, 1997, European journal of pharmacology.

Direct visualization of mitochondrial zinc accumulation reveals uniporter‐dependent and ‐independent transport mechanisms

I. Reynolds, O. Vergun, K. Dineley, 2005, Journal of neurochemistry.

Nitric oxide-induced changes in intracellular zinc homeostasis are mediated by metallothionein/thionein.

C. S. St. Croix, K. Wasserloos, B. Pitt, 2002, American journal of physiology. Lung cellular and molecular physiology.

Calcium antagonist receptors.

S. Snyder, I. Reynolds, S. Snyder, 1988, Ion channels.

Calcium antagonist receptors in cardiomyopathic hamster: selective increases in heart, muscle, brain.

S. Snyder, M. Weisfeldt, H. Weisman, 1986, Science.

Nuclear and Mitochondrial Interaction Involving mt-Nd2 Leads to Increased Mitochondrial Reactive Oxygen Species Production*

C. Mathews, I. Reynolds, T. Votyakova, 2007, Journal of Biological Chemistry.

The targeted eosinophil-lowering effects of dexpramipexole in clinical studies.

I. Reynolds, S. Dworetzky, M. Bozik, 2017, Blood cells, molecules & diseases.

Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death

Christian M. Metallo, Ajit S. Divakaruni, L. Raymond, 2017, The Journal of cell biology.

Oxidized glutathione modulates N-methyl-d-aspartate- and depolarization-induced increases in intracellular Ca2+ in cultured rat forebrain neurons

I. Reynolds, E. Aizenman, Kari R. Gilbert, 1991, Neuroscience Letters.

Calcium antagonist receptors. Clinical and physiological relevance.

S. Snyder, A. Snowman, J. Wagner, 1988, Annals of the New York Academy of Sciences.

Studies on the effects of several pentamidine analogues on the NMDA receptor.

I. Reynolds, E. Aizenman, K. Rothermund, 1993, European journal of pharmacology.

Serotonin increases DNA synthesis in rat proximal and distal pulmonary vascular smooth muscle cells in culture.

R. Blakely, B. Pitt, I. Reynolds, 1994, The American journal of physiology.

Quantitative evaluation of mitochondrial calcium content in rat cortical neurones following a glutamate stimulus

I. Reynolds, J. Brocard, M. Tassetto, 2001, The Journal of physiology.

Astrocytes Are More Resistant Than Neurons to the Cytotoxic Effects of Increased [Zn2+]i

G. Kress, I. Reynolds, J. Scanlon, 2000, Neurobiology of Disease.

Nitric oxide decreases the sensitivity of pulmonary endothelial cells to LPS-induced apoptosis in a zinc-dependent fashion

C. S. St. Croix, M. Stitt, K. Wasserloos, 2004, Molecular and Cellular Biochemistry.

Modulation of [3H]flunitrazepam binding by natural and synthetic progestational agents

P. Kroboth, I. Reynolds, D. Stiff, 1993, Pharmacology Biochemistry and Behavior.

Effect of neuroactive steroids on [3H]flumazenil binding to the GABAA receptor complex in vitro

P. Kroboth, I. Reynolds, R. Bertz, 1995, Neuropharmacology.

Orally administered progesterone enhances sensitivity to triazolam in postmenopausal women.

P. Kroboth, I. Reynolds, F. Kroboth, 1995, Journal of clinical psychopharmacology.

Nitric oxide decreases the sensitivity of pulmonary endothelial cells to LPS-induced apoptosis in a zinc-dependent fashion.

M. Stitt, K. Wasserloos, B. Pitt, 2002 .

Distinct characteristics of Ca(2+)-induced depolarization of isolated brain and liver mitochondria.

I. Reynolds, O. Vergun, 2005, Biochimica et biophysica acta.

Ca2+‐induced permeabilization promotes free radical release from rat brain mitochondria with partially inhibited complex I

I. Reynolds, T. Votyakova, 2005, Journal of neurochemistry.

Desensitization of 5HT2 Receptors by Protein Kinase C Activation in Distal Pulmonary Vascular Smooth Muscle Cells in Culture

S. Sebti, B. Pitt, I. Reynolds, 1994, Microcirculation.

Zinc causes loss of membrane potential and elevates reactive oxygen species in rat brain mitochondria.

I. Reynolds, T. Votyakova, K. Dineley, 2005, Mitochondrion.

Elevated intracellular zinc and altered proton homeostasis in forebrain neurons

I. Reynolds, J. Brocard, K. Dineley, 2002, Neuroscience.

Alkalinization Prolongs Recovery from Glutamate‐Induced Increases in Intracellular Ca2+ Concentration by Enhancing Ca2+ Efflux Through the Mitochondrial Na+/Ca2+ Exchanger in Cultured Rat Forebrain Neurons

K. Hoyt, I. Reynolds, 1998, Journal of neurochemistry.

[3H](+)MK801 Radioligand Binding Assay at the N‐Methyl‐D‐Aspartate Receptor

I. Reynolds, 2000, Current protocols in pharmacology.

The use of ligand binding in assays of NMDA receptor function.

I. Reynolds, T. A. Sharma, 1999, Methods in molecular biology.

Direct and allosteric control of glutamate receptors

P. Skolnick, I. Reynolds, M. Palfreyman, 1994 .

Measurement of Cation Movement in Primary Cultures Using Fluorescent Dyes

I. Reynolds, 1998, Current protocols in neuroscience.

Detection of hydrogen peroxide with Amplex Red: interference by NADH and reduced glutathione auto-oxidation.

I. Reynolds, T. Votyakova, 2004, Archives of biochemistry and biophysics.

Apoptosis and the laws of thermodynamics

M. Brand, D. Nicholls, I. Reynolds, 2000, Nature Cell Biology.

Interaction of rigid polyamine analogues with the NMDA receptor complex from rat brain

I. Reynolds, S. Rajdev, K. Rothermund, 1993 .

Persistent Activation of ERK Contributes to Glutamate-induced Oxidative Toxicity in a Neuronal Cell Line and Primary Cortical Neuron Cultures*

Jon W. Johnson, E. Klann, D. DeFranco, 2000, The Journal of Biological Chemistry.

Multiple sites for the regulation of the N-methyl-D-aspartate receptor.

R. Miller, I. Reynolds, Richard J. Miller, 1988, Molecular pharmacology.

NMDA Receptor‐Mediated Neurotoxicity: A Paradoxical Requirement for Extracellular Mg2+ in Na+/Ca2+‐Free Solutions in Rat Cortical Neurons In Vitro

P. Rosenberg, I. Reynolds, S. Rajdev, 1997, Journal of neurochemistry.

Effects of Monovalent and Divalent Cations on 3‐(+)[125I]Iododizocilpine Binding to the N‐Methyl‐d‐Aspartate Receptor of Rat Brain Membranes

I. Reynolds, S. Rajdev, 1992, Journal of neurochemistry.

Modulation of NMDA receptor responsiveness by neurotransmitters, drugs and chemical modification.

I. Reynolds, 1990, Life sciences.

Synthesis of a potent wide-spectrum serotonin-, norepinephrine-, dopamine-reuptake inhibitor (SNDRI) and a species-selective dopamine-reuptake inhibitor based on the gamma-amino alcohol functional group.

P. Carlier, I. Reynolds, E. Richelson, 1998, Bioorganic & medicinal chemistry letters.

4.7 Ion Transport and Energy Metabolism

I. Reynolds, O. Vergun, K. Dineley, 2007 .

Emergence of excitotoxicity in cultured forebrain neurons coincides with larger glutamate-stimulated [Ca2+]i increases and NMDA receptor mRNA levels

D. Fass, I. Reynolds, Chialin Cheng, 1999, Brain Research.

Epidermal Growth Factor Activates m-Calpain (Calpain II), at Least in Part, by Extracellular Signal-Regulated Kinase-Mediated Phosphorylation

R. Bodnar, A. Wells, D. Potter, 2004, Molecular and Cellular Biology.

Fluorescence Detection of Redox‐Sensitive Metals in Neuronal Culture: Focus on Iron and Zinc

I. Reynolds, 2004, Annals of the New York Academy of Sciences.

Ectopic Expression of the Catalytic Subunit of Telomerase Protects against Brain Injury Resulting from Ischemia and NMDA-Induced Neurotoxicity

H. K. Jeon, Han-Woong Lee, R. Bachoo, 2004, The Journal of Neuroscience.

Zinc inhibition of cellular energy production: implications for mitochondria and neurodegeneration

I. Reynolds, T. Votyakova, K. Dineley, 2003, Journal of neurochemistry.

A reevaluation of neuronal zinc measurements: artifacts associated with high intracellular dye concentration.

I. Reynolds, K. Dineley, L. Malaiyandi, 2002, Molecular pharmacology.

The Relationship between Intracellular Free Iron and Cell Injury in Cultured Neurons, Astrocytes, and Oligodendrocytes

G. Kress, I. Reynolds, K. Dineley, 2002, The Journal of Neuroscience.

Allosteric modulation of N-methyl-D-aspartate receptors.

R. Miller, I. Reynolds, 1990, Advances in pharmacology.

Reverse Na+/Ca2+ exchange contributes to glutamate-induced intracellular Ca2+ concentration increases in cultured rat forebrain neurons.

K. Hoyt, I. Reynolds, E. Aizenman, 1998, Molecular pharmacology.

Intracellular calcium and magnesium: critical determinants of excitotoxicity?

I. Reynolds, 1998, Progress in brain research.

Muscarinic Agonists Cause Calcium Influx and Calcium Mobilization in Forebrain Neurons In Vitro

R. Miller, I. Reynolds, Richard J. Miller, 1989, Journal of neurochemistry.

Glutamate-induced neuron death requires mitochondrial calcium uptake

Ian J. Reynolds, Eric Klann, E. Klann, 1998, Nature Neuroscience.

Apolipoprotein E4 Domain Interaction Mediates Detrimental Effects on Mitochondria and Is a Potential Therapeutic Target for Alzheimer Disease*

R. Mahley, K. Weisgraber, Yadong Huang, 2010, The Journal of Biological Chemistry.

Effects of nicotinic agonists on the NMDA receptor

I. Reynolds, E. Aizenman, L. Tang, 1991, Brain Research.

Localization of D1 dopamine receptors on live cultured striatal neurons by quantitative fluorescence microscopy

K. Hoyt, I. Reynolds, 1996, Brain Research.

Mitochondrial trafficking and morphology in healthy and injured neurons

I. Reynolds, Diane T. W. Chang, 2006, Progress in Neurobiology.

Trifluoperazine and dibucaine‐induced inhibition of glutamate‐induced mitochondrial depolarization in rat cultured forebrain neurones

K. Hoyt, I. Reynolds, T. A. Sharma, 1997, British journal of pharmacology.

Spontaneous Changes in Mitochondrial Membrane Potential in Cultured Neurons

Ian J. Reynolds, Jennifer F. Buckman, I. Reynolds, 2001, The Journal of Neuroscience.

Inhibition of glutamate-induced mitochondrial depolarization by tamoxifen in cultured neurons.

K. Hoyt, B. McLaughlin, I. Reynolds, 2000, The Journal of pharmacology and experimental therapeutics.

Differences in mitochondrial movement and morphology in young and mature primary cortical neurons in culture

I. Reynolds, Diane T. W. Chang, I.J Reynolds, 2006, Neuroscience.

Mitochondrial trafficking and morphology in neuronal injury.

I. Reynolds, G. Rintoul, 2010, Biochimica et biophysica acta.

Brain voltage-sensitive calcium channel subtypes differentiated by ω-conotoxin fraction GVIA

S. Snyder, Richard J. Miller, J. Wagner, 1986 .

Brain voltage-sensitive calcium channel subtypes differentiated by omega-conotoxin fraction GVIA.

S. Snyder, R. Miller, J. Wagner, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Tricyclic antidepressants block N‐methyl‐D‐aspartate receptors: similarities to the action of zinc

I. Reynolds, Ian J. Reynolds, Richard J. Miller, 1988, British journal of pharmacology.

3H-labeled MK-801 binding to the excitatory amino acid receptor complex from rat brain is enhanced by glycine.

R. Miller, I. Reynolds, S. N. Murphy, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Thermal nociception and TRPV1 function are attenuated in mice lacking the nucleotide receptor P2Y2

H. Koerber, B. Davis, I. Reynolds, 2008, PAIN.

[3H]Verapamil binding sites in brain and skeletal muscle: regulation by calcium.

S. Snyder, I. Reynolds, R. Gould, 1983, European journal of pharmacology.

Discovery of 1,4-substituted piperidines as potent and selective inhibitors of T-type calcium channels.

Steven V. Fox, S. Doran, W. Shipe, 2008, Journal of medicinal chemistry.

The Multifaceted Roles of Zinc in Neuronal Mitochondrial Dysfunction

I. Reynolds, E. Aizenman, J. Weiss, 2021, Biomedicines.

Epidermal Growth Factor Activates m-Calpain (Calpain II), at Least in Part, by Extracellular Signal-Regulated Kinase-Mediated Phosphorylation

R. Bodnar, A. Wells, D. Potter, 2004, Molecular and Cellular Biology.

DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria.

I. Reynolds, T. Votyakova, T V Votyakova, 2001, Journal of neurochemistry.

Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists.

S. Snyder, K. Murphy, I. Reynolds, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Induction of Neuronal Apoptosis by Thiol Oxidation

B. McLaughlin, I. Reynolds, E. Aizenman, 2000, Journal of neurochemistry.

Calcium channel blockade: possible explanation for thioridazine's peripheral side effects.

S. Snyder, K. Murphy, I. Reynolds, 1984, The American journal of psychiatry.

Ifenprodil is a novel type of N-methyl-D-aspartate receptor antagonist: interaction with polyamines.

R. Miller, I. Reynolds, Richard J. Miller, 1989, Molecular pharmacology.

Calcium green-5N, a novel fluorescent probe for monitoring high intracellular free Ca2+ concentrations associated with glutamate excitotoxicity in cultured rat brain neurons

I. Reynolds, S. Rajdev, 1993, Neuroscience Letters.

Role of the Permeability Transition in Glutamate-Mediated Neuronal Injury

I. Reynolds, T. Hastings, 2002 .

Divergent consequences arise from metallothionein overexpression in astrocytes: Zinc buffering and oxidant‐induced zinc release

I. Reynolds, K. Dineley, L. Malaiyandi, 2004, Glia.

High throughput monitoring of amyloid-β(42) assembly into soluble oligomers achieved by sensitive conformation state-dependent immunoassays.

Dawn M. Toolan, J. Renger, Wei⁃qin Zhao, 2011, Journal of Alzheimer's disease : JAD.

Glucose deprivation produces a prolonged increase in sensitivity to glutamate in cultured rat cortical neurons

Y. Han, I. Reynolds, O. Vergun, 2003, Experimental Neurology.

[3H]MK801 binding to the N-methyl-D-aspartate receptor reveals drug interactions with the zinc and magnesium binding sites.

R. Miller, I. Reynolds, Richard J. Miller, 1988, The Journal of pharmacology and experimental therapeutics.

Alterations in Calcium Antagonist Receptors and Sodium-Calcium Exchange in Cardiomyopathic Hamster Tissues

S. Snyder, M. Weisfeldt, A. Snowman, 1989, Circulation research.

Glutamate Decreases Mitochondrial Size and Movement in Primary Forebrain Neurons

G. Kress, I. Reynolds, A. Filiano, 2003, The Journal of Neuroscience.

Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons

Ian J. Reynolds, I. Reynolds, Sruthi Pandipati, 2006, Neurobiology of Disease.

Synthesis and biological activity of 8a-phenyldecahydroquinolines as probes of PCP's binding conformation. A new PCP-like compound with increased in vivo potency.

Y. Pang, A. Kozikowski, I. Reynolds, 1992, Journal of Medicinal Chemistry.

[3H]MK801 binding to the NMDA receptor/ionophore complex is regulated by divalent cations: evidence for multiple regulatory sites.

R. Miller, I. Reynolds, Richard J. Miller, 1988, European journal of pharmacology.

The spider toxin, argiotoxin636, binds to a Mg2+ site on the N‐methyl‐d‐aspartate receptor complex

I. Reynolds, 1991, British journal of pharmacology.

PISA, a novel pharmacodynamic assay for assessing poly(ADP-ribose) polymerase (PARP) activity in situ.

S. Browne, L. Lubbers, I. Reynolds, 2010, Journal of pharmacological and toxicological methods.

A Potent and Selective Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator Improves Movement in Rodent Models of Parkinson's Disease

A. Dilella, K. Smith, S. Browne, 2012, Journal of Pharmacology and Experimental Therapeutics.

High-affinity calcium indicators underestimate increases in intracellular calcium concentrations associated with excitotoxic glutamate stimulations

I. Reynolds, A. Stout, 1999, Neuroscience.

Nitric oxide inhibits mitochondrial movement in forebrain neurons associated with disruption of mitochondrial membrane potential

I. Reynolds, V. Bennett, G. Rintoul, 2006, Journal of neurochemistry.

Mitochondrial Stop and Go: Signals That Regulate Organelle Movement

I. Reynolds, G. Rintoul, 2004, Science's STKE.

Cyclothiazide Modulates AMPA Receptor‐Mediated Increases in Intracellular Free Ca2+ and Mg2+ in Cultured Neurons from Rat Brain

K. Hoyt, I. Reynolds, S. Rajdev, 1995, Journal of neurochemistry.

Mechanisms of Dopamine-Induced Cell Death in Cultured Rat Forebrain Neurons: Interactions with and Differences from Glutamate-Induced Cell Death

K. Hoyt, I. Reynolds, T. Hastings, 1997, Experimental Neurology.

[3H] CGP 39653 Binding to the Agonist Site of the N‐Methyl‐ D‐Aspartate Receptor Is Modulated by Mg2+ and Polyamines Independently of the Arcaine‐Sensitive Polyamine Site

I. Reynolds, 1994, Journal of neurochemistry.

Mitochondria in Acute Brain Injury

Y. Han, I. Reynolds, 2001 .

Effects of the selective adenosine A2A receptor antagonist, SCH 412348, on the parkinsonian phenotype of MitoPark mice.

K. Smith, R. Hodgson, S. Browne, 2014, European journal of pharmacology.

Effects of age and visual experience on [3H] MK801 binding to NMDA receptors in the kitten visual cortex

M. Bear, I. Reynolds, 2004, Experimental Brain Research.

The Neuropharmacology of Ca2+ Channels

T. Perney, Richard J. Miller, I. Reynolds, 1988 .

Synaptosomal dopamine uptake in rat striatum following controlled cortical impact

D. Ren, A. Wagner, C. Dixon, 2005, Journal of neuroscience research.

Nitric oxide modulates NMDA-induced increases in intracellular Ca2+ in cultured rat forebrain neurons

K. Hoyt, I. Reynolds, E. Aizenman, 1992, Brain Research.

H-labeled MK-801 binding to the excitatory amino acid receptor complex from rat brain is enhanced by glycine ( N-methyl-n-aspartate receptor / fura-2 )

Richard J. Miller, I. Reynolds, S. N. Murphy, 2022 .

Alprazolam in young and elderly men: sensitivity and tolerance to psychomotor, sedative and memory effects.

F. Salek, P. Kroboth, I. Reynolds, 1997, The Journal of pharmacology and experimental therapeutics.

Mechanisms of glutamate‐stimulated Mg2+ influx and subsequent Mg2+ efflux in rat forebrain neurones in culture.

I. Reynolds, J. Johnson, A. Stout, 1996, The Journal of physiology.

Arcaine uncovers dual interactions of polyamines with the N-methyl-D-aspartate receptor.

I. Reynolds, 1990, The Journal of pharmacology and experimental therapeutics.

Novel bisbenzamidines and bisbenzimidazolines as noncompetitive NMDA receptor antagonists.

I. Reynolds, I. Donkor, T. Huang, 1999, Bioorganic & medicinal chemistry letters.

Characterization of the effects of polyamines on [125I]MK-801 binding to recombinant N-methyl-D-aspartate receptors.

I. Reynolds, T. A. Sharma, 1999, The Journal of pharmacology and experimental therapeutics.

Characterization of the effects of polyamines on the modulation of the N-methyl-d-aspartate receptor by glycine

I. Reynolds, K. Rothermund, 1995, Neuropharmacology.

Effects of pH on the actions of dizocilpine at the N‐methyl‐D‐aspartate receptor complex

I. Reynolds, S. Rajdev, 1993, British journal of pharmacology.

[125I]thienylphencyclidine, a novel ligand for the NMDA receptor.

A. Kozikowski, I. Reynolds, S. Rajdev, 1992, European journal of pharmacology.

1,5-(Diethylamino)piperidine, a novel spermidine analogue that more specifically activates the N-methyl-D-aspartate receptor-associated polyamine site.

I. Reynolds, 1992, Molecular pharmacology.

Regional Variations in [3H]MK801 Binding to Rat Brain N‐Methyl‐D‐Aspartate Receptors

I. Reynolds, A. Palmer, 1991, Journal of neurochemistry.

Transcriptional responses to loss or gain of function of the leucine-rich repeat kinase 2 (LRRK2) gene uncover biological processes modulated by LRRK2 activity.

D. Stone, T. Dawson, V. Dawson, 2012, Human molecular genetics.

Zn2+ Inhibits Mitochondrial Movement in Neurons by Phosphatidylinositol 3-Kinase Activation

I. Reynolds, Q. Wang, Anthony S. Honick, 2005, The Journal of Neuroscience.

Calcium‐Sensitive Fluorescent Dyes Can Report Increases in Intracellular Free Zinc Concentration in Cultured Forebrain Neurons

I. Reynolds, Chialin Cheng, 1998, Journal of neurochemistry.

Guanine nucleotides are competitive inhibitors of N-methyl-D-aspartate at its receptor site both in vitro and in vivo.

C. J. Schmidt, I. Reynolds, B. M. Baron, 1989, The Journal of pharmacology and experimental therapeutics.

Dopaminergic neurotoxins require excitotoxic stimulation in organotypic cultures

Ian J. Reynolds, G. Kress, I. Reynolds, 2005, Neurobiology of Disease.

A Characterization of Dopaminergic Neurodegeneration in Organotypic Cultures

G. Kress, I. Reynolds, 2003 .

Physiological and Pharmacological Correlates of Calcium Antagonist Receptors

S. Snyder, I. Reynolds, J. A. Wagner, 1987, Journal of cardiovascular pharmacology.

Pharmacological investigation of mitochondrial ca(2+) transport in central neurons: studies with CGP-37157, an inhibitor of the mitochondrial Na(+)-Ca(2+) exchanger.

I. Reynolds, J. Scanlon, J. Brocard, 2000, Cell calcium.

PET imaging of brain macrophages using the peripheral benzodiazepine receptor in a macaque model of neuroAIDS.

S. Wisniewski, C. Mathis, C. Meltzer, 2004, The Journal of clinical investigation.

A potent and selective mGluR4 positive allosteric modulator improves movement in rodent models of Parkinson's disease

A. Dilella, K. Smith, S. Browne, 2012 .

Excitatory amino acid receptors: NMDA modulatory sites, kainate cloned and a new role in AIDS

I. Reynolds, J. Lehmann, J. Randle, 1990 .

Synthesis and Evaluation of Fluoromycin: A Novel Fluorescence-labeled Derivative of Talisomycin Siot,1

J. Lazo, S. Sebti, R. Mujumdar, 2006 .

NMDA receptor antagonists that bind to the strychnine-insensitive glycine site and inhibit NMDA-induced Ca2+ fluxes and [3H]GABA release.

R. Miller, I. Reynolds, K. Harris, 1989, European journal of pharmacology.

Intracellular Signalling in Glutamate Excitotoxicity

K. Hoyt, I. Reynolds, R. White, 1996 .

Molecular Zn 2 Inhibits Mitochondrial Movement in Neurons by Phosphatidylinositol 3-Kinase Activation

I. Reynolds, Q. Wang, Anthony S. Honick, 2005 .

Synthesis and bioactivity of a new class of rigid glutamate analogues. Modulators of the N-methyl-D-aspartate receptor.

J. Wroblewski, A. Kozikowski, I. Reynolds, 1990, Journal of medicinal chemistry.