A. Thomas

发表

Propagation of cytosolic calcium waves into the nuclei of hepatocytes.

G. Hajnóczky, C. Lin, A. Thomas, 1994, Cell calcium.

Interactions between insulin and alpha 1-adrenergic agents in the regulation of glycogen metabolism in isolated hepatocytes.

J. Williamson, A. Thomas, Á. Martín-Requero, 1985, The Journal of biological chemistry.

Intracellular acidosis protects cultured hepatocytes from the toxic consequences of a loss of mitochondrial energization.

J. Hoek, J. Farber, A. Thomas, 1989, Archives of biochemistry and biophysics.

Subcellular organization of calcium signalling in hepatocytes and the intact liver.

G. Hajnóczky, C. Lin, A. Thomas, 1995, Ciba Foundation symposium.

Heteroligomers of Type-I and Type-III Inositol Trisphosphate Receptors in WB Rat Liver Epithelial Cells (*)

C. Lin, A. Thomas, S. Joseph, 1995, The Journal of Biological Chemistry.

Quantitation and early kinetics of inositol lipid changes induced by vasopressin in isolated and cultured hepatocytes.

J. Williamson, J. Marks, A. Thomas, 1983, The Journal of biological chemistry.

myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver.

J. Williamson, A. Thomas, S. Joseph, 1984, The Journal of biological chemistry.

Relationship between inositol polyphosphate production and the increase of cytosolic free Ca2+ induced by vasopressin in isolated hepatocytes.

J. Williamson, A. Thomas, J. Alexander, 1984, The Journal of biological chemistry.

Inhibition of hepatic inositol 1,4,5-trisphosphate receptor function by ethanol and other short chain alcohols.

A. Thomas, M. Seitz, D. Renard-Rooney, 1997, Cell calcium.

Calcium ion-dependent signalling and mitochondrial dysfunction: mitochondrial calcium uptake during hormonal stimulation in intact liver cells and its implication for the mitochondrial permeability transition.

J. Hoek, J. Farber, A. Thomas, 1995, Biochimica et biophysica acta.

Ethanol and signal transduction in the liver

J. Hoek, A. Thomas, K. Higashi, 1992, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Effects of ethanol on the contractile function of the heart: a review.

A. Thomas, E. Rubin, A. Thomas, 1994, Alcoholism, clinical and experimental research.

Inhibition of type I and III IP(3)Rs by TGF-beta is associated with impaired calcium release in mesangial cells.

M. Madesh, G. Hajnóczky, K. Sharma, 2000, American journal of physiology. Renal physiology.

Mitochondrial pyruvate transport and its hormonal regulation.

A. Thomas, A. Halestrap, R. D. Scott, 1980, The International journal of biochemistry.

Alpha-adrenergic modification of the Ca2+ transient and contraction in single rat cardiomyocytes.

B. O’Rourke, A. Thomas, D. Reibel, 1992, Journal of molecular and cellular cardiology.

Ethanol inhibits electrically-induced calcium transients in isolated rat cardiac myocytes.

A. Thomas, E. Sass, E. Rubin, 1989, Journal of molecular and cellular cardiology.

Mechanisms Whereby Insulin and Other Hormones Binding to Cell Surface Receptors Influence Metabolic Pathways within the Inner Membrane of Mitochondria a

R. Denton, J. Mccormack, R. Denton, 1986, Annals of the New York Academy of Sciences.

Gender-specific proteomic alterations in glycolytic and mitochondrial pathways in aging monkey hearts.

F. Natividad, S. Vatner, E. Lewandowski, 2004, Journal of molecular and cellular cardiology.

Identification of the protein responsible for pyruvate transport into rat liver and heart mitochondria by specific labelling with [3H]N-phenylmaleimide.

A. Thomas, A. Halestrap, 1981, The Biochemical journal.

Modulation of cardiac Ca2+ channels by IGF1.

A. Thomas, M. Solem, 1998, Biochemical and biophysical research communications.

CD148 is a membrane protein tyrosine phosphatase present in all hematopoietic lineages and is involved in signal transduction on lymphocytes.

J. Freed, R. Vilella, A. Thomas, 1998, Blood.

Ethanol-induced phospholipase C activation is inhibited by phorbol esters in isolated hepatocytes.

J. Hoek, A. Thomas, R. Rubin, 1988, The Biochemical journal.

Ethanol does not stimulate guanine nucleotide-induced activation of phospholipase C in permeabilized hepatocytes.

J. Hoek, A. Thomas, R. Rubin, 1987, Archives of biochemistry and biophysics.

Luminal communication between intracellular calcium stores modulated by GTP and the cytoskeleton.

G. Hajnóczky, C. Lin, A. Thomas, 1994, The Journal of biological chemistry.

Enhancement of the inositol 1,4,5-trisphosphate-releasable Ca2+ pool by GTP in permeabilized hepatocytes.

A. Thomas, 1988, The Journal of biological chemistry.

The Effect of Mersalyl on Inositol Trisphosphate Receptor Binding and Ion Channel Function (*)

A. Thomas, S. Joseph, D. Renard-Rooney, 1995, The Journal of Biological Chemistry.

Mouse monoclonal antipeptide antibodies specific for cholesteryl ester transfer protein (CETP).

A. Thomas, R. Thomas, A. Smith, 1996, Hybridoma.

Effects of Ca2+ and Mg2+ on the activity of pyruvate dehydrogenase phosphate phosphatase within toluene-permeabilized mitochondria.

G. Rutter, R. Denton, A. Thomas, 1987, The Biochemical journal.

Ethanol acutely decreases calcium transients in cultured human myotubes.

J. Fernandez-Solà, R. Estruch, A. Thomas, 1998, Alcoholism, clinical and experimental research.

Oxidized glutathione causes sensitization of calcium release to inositol 1,4,5-trisphosphate in permeabilized hepatocytes.

A. Thomas, M. Seitz, D. Renard, 1992, The Biochemical journal.

Beta-adrenergic receptor-mediated phospholipase C activation independent of cAMP formation in turkey erythrocyte membranes.

A. Thomas, T. A. Rooney, R. Hager, 1991, The Journal of biological chemistry.

Increases in cytosolic calcium ion concentration can be dissociated from the killing of cultured hepatocytes by tert-butyl hydroperoxide.

J. Farber, A. Thomas, I. Sakaida, 1991, The Journal of biological chemistry.

Arginine vasopressin induces contraction and stimulates growth of cultured human hepatic stellate cells.

R. Bataller, E. García-Ramallo, W. Jiménez, 1997, Gastroenterology.

The role of Ca2+ in the hormonal control of intramitochondrial metabolism in heart, liver, and adipose tissue.

J. Mccormack, G. Rutter, R. Denton, 1988, Advances in second messenger and phosphoprotein research.

Use of toluene-permeabilized mitochondria to study the regulation of adipose tissue pyruvate dehydrogenase in situ. Further evidence that insulin acts through stimulation of pyruvate dehydrogenase phosphate phosphatase.

R. Denton, A. Thomas, 1986, The Biochemical journal.

Single cell and subcellular measurement of intracellular Ca2+ concentration ([Ca2+]i).

A. Thomas, A. Morgan, 1999, Methods in molecular biology.

Imaging of inositol 1,4,5-trisphosphate-induced Ca2+ fluxes in single permeabilized hepatocytes. Demonstration of both quantal and nonquantal patterns of Ca2+ release.

G. Hajnóczky, A. Thomas, M. Seitz, 1993, The Journal of biological chemistry.

Contraction of human hepatic stellate cells activated in culture: a role for voltage-operated calcium channels.

R. Bataller, E. García-Ramallo, V. Arroyo, 1998, Journal of hepatology.

Ethanol and cocaine cause additive inhibitory effects on the calcium transients and contraction in single cardiomyocytes.

A. Thomas, E. Rubin, J. Nicolás, 1996, Alcoholism, clinical and experimental research.

Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors.

J. Kendrew, P. Plé, J. Curwen, 1999, Journal of medicinal chemistry.

New nonpeptide angiotensin II receptor antagonists. 1. Synthesis, biological properties, and structure-activity relationships of 2-alkyl benzimidazole derivatives.

J. Major, K. Gibson, C. Allott, 1992, Journal of medicinal chemistry.

Organization of intracellular calcium signals generated by inositol lipid-dependent hormones.

A. Thomas, T. A. Rooney, 1991, Pharmacology & therapeutics.

Ethanol-induced mobilization of calcium by activation of phosphoinositide-specific phospholipase C in intact hepatocytes.

J. Hoek, A. Thomas, R. Rubin, 1987, The Journal of biological chemistry.

ATP synthase activity is required for fructose to protect cultured hepatocytes from the toxicity of cyanide.

J. Farber, A. Thomas, J. Hoek, 1993, The American journal of physiology.

Molecular properties of inositol 1,4,5-trisphosphate receptors.

S. Patel, A. Thomas, A P Thomas, 1999, Cell calcium.

Spatial and temporal organization of calcium signalling in hepatocytes.

A. Thomas, T. A. Rooney, D. Renard, 1991, Cell calcium.

The role of extracellular Ca2+ in the response of the hepatocyte to Ca2+-dependent hormones.

J. Williamson, A. Thomas, K. Coll, 1985, The Journal of biological chemistry.

Intracellular calcium waves generated by Ins(1,4,5)P3-dependent mechanisms.

A. Thomas, A P Thomas, T. A. Rooney, 1993, Cell calcium.

Coupling between cytosolic and mitochondrial calcium oscillations: role in the regulation of hepatic metabolism.

G. Rutter, G. Hajnóczky, R. Denton, 1998, Biochimica et Biophysica Acta.

Inositol trisphosphate and diacylglycerol as intracellular second messengers in liver.

R. Cooper, A. Thomas, S. Joseph, 1985, The American journal of physiology.

Cellular activation by Ca2+ release from stores in the endoplasmic reticulum but not by increased free Ca2+ in the cytosol.

J. Hoek, M. White, D. Strayer, 1999, The Biochemical journal.

Changes in activity and regulation of the cardiac Ca2+ channel (L-type) by protein kinase C in chronic alcohol-exposed rats.

A. Thomas, E. Rubin, M. Solem, 2000, Alcoholism, clinical and experimental research.

Novel kinetics of single cell Ca2+ transients in stimulated hepatocytes and A10 cells measured using fura-2 and fluorescent videomicroscopy.

J. R. Monck, J. Williamson, A. Thomas, 1988, The Journal of biological chemistry.

Calcium compartmentation and regulation in myocytes.

M. Selak, J. Williamson, A. Thomas, 1986, Advances in experimental medicine and biology.

Cell-specific patterns of oscillating free Ca2+ in carbamylcholine-stimulated insulinoma cells.

F M Matschinsky, M. Prentki, B. Corkey, 1988, The Journal of biological chemistry.

Influence of calcium and iron on cell death and mitochondrial function in oxidatively stressed astrocytes

J. Connor, A. Thomas, L. D. Robb-Gaspers, 1999, Journal of neuroscience research.

Physiological concentrations of nitric oxide do not elicit an acute negative inotropic effect in unstimulated cardiac muscle.

A. M. Lefer, T. Murohara, D. Lefer, 1994, Circulation research.

Agonist-induced cytosolic calcium oscillations originate from a specific locus in single hepatocytes.

A. Thomas, E. Sass, T. A. Rooney, 1990, The Journal of biological chemistry.

Halothane regulates G-protein-dependent phospholipase C activity in turkey erythrocyte membranes.

C. Stubbs, A. Thomas, T. A. Rooney, 1993, The Journal of biological chemistry.

Inhibition by cocaine of excitation-contraction coupling in isolated cardiomyocytes.

A. Thomas, E. Rubin, G. Stewart, 1991, The American journal of physiology.

Phospholipid metabolism and intracellular Ca2+ homeostasis in cultured rat hepatocytes intoxicated with cyanide.

J. Farber, A. Thomas, I. Sakaida, 1992, The American journal of physiology.

Oscillatory cytosolic calcium waves independent of stimulated inositol 1,4,5-trisphosphate formation in hepatocytes.

A. Thomas, E. Sass, T. A. Rooney, 1991, The Journal of biological chemistry.

Effects of insulin on phenylephrine-induced activation of phosphorylase and phosphatidylinositol turnover in isolated hepatocytes.

J. Williamson, A. Thomas, 1983, The Journal of biological chemistry.

Carbachol-stimulated Ca2+ increase in single neuroblastoma SH-SY5Y cells: effects of ethanol.

J. Hoek, C. Larsson, A. Thomas, 1998, Alcoholism, clinical and experimental research.

Multiple mechanisms by which protein kinase A potentiates inositol 1,4,5-trisphosphate-induced Ca2+ mobilization in permeabilized hepatocytes.

J. Hoek, G. Hajnóczky, A. Thomas, 1993, The Biochemical journal.

Characterization of cytosolic calcium oscillations induced by phenylephrine and vasopressin in single fura-2-loaded hepatocytes.

E J Sass, A. Thomas, E. Sass, 1989, The Journal of biological chemistry.

Tonic regulation of excitation-contraction coupling by basal protein kinase C activity in isolated cardiac myocytes.

A. Thomas, D. Renard-Rooney, J. Nicolás, 1998, Journal of molecular and cellular cardiology.

Inhibitory effects of cocaine on Ca2+ transients and contraction in single cardiomyocytes.

A. Thomas, D. Renard, F. Delaville, 1994, The American journal of physiology.

Measurement of the intramitochondrial volume in hepatocytes without cell disruption and its elevation by hormones and valinomycin.

A. Thomas, A. Halestrap, P. Quinlan, 1983, The Biochemical journal.

The rôle of mitochondrial pyruvate transport in the stimulation by glucagon and phenylephrine of gluconeogenesis from L-lactate in isolated rat hepatocytes.

A. Thomas, A. Halestrap, Andrew P. Thomas, 1981, The Biochemical journal.

Calcium signal transmission between ryanodine receptors and mitochondria in cardiac muscle.

G. Hajnóczky, A. Thomas, G. Csordás, 2001, Trends in cardiovascular medicine.

Surfactant protein-A receptor-mediated inhibition of calcium signaling in alveolar type II cells.

D. Strayer, A. Thomas, L. Korutla, 1997, Receptors & signal transduction.

Measurement of electrically-induced Ca2+ transients in Quin2-loaded cardiac myocytes.

M. Selak, J. Williamson, A. Thomas, 1986, Journal of molecular and cellular cardiology.

Effect of oxidized glutathione and temperature on inositol 1,4,5-trisphosphate binding in permeabilized hepatocytes.

A. Thomas, M. Seitz, S. Joseph, 1995, The Biochemical journal.

Effect of guanine nucleotides on polyphosphoinositide synthesis in rat liver plasma membranes.

A. Thomas, R. Rubin, C. Benistant, 1990, The Biochemical journal.

Ethanol stimulates shape change in human platelets by activation of phosphoinositide-specific phospholipase C.

J. Hoek, A. Thomas, R. Rubin, 1988, Archives of biochemistry and biophysics.

Sensitivity of pyruvate dehydrogenase phosphate phosphatase to magnesium ions. Similar effects of spermine and insulin.

R. Denton, T. Diggle, A. Thomas, 1986, The Biochemical journal.

Spatial organization of Ca2+ signalling and Ins(1,4,5)P3 action.

A. Thomas, T. A. Rooney, D. Renard, 1992, Advances in second messenger and phosphoprotein research.

Phospholipase C activation by ethanol in rat hepatocytes is unaffected by chronic ethanol feeding.

J. Hoek, A. Thomas, K. Higashi, 1990, The Biochemical journal.

Spatial organization of oscillating calcium signals in liver.

G. Hajnóczky, C. Lin, A. Thomas, 1995, Biochemical Society transactions.

Potentiation by GTP of Ins(1,4,5)P3-induced Ca2+ mobilization in permeabilized hepatocytes.

A. Thomas, 1988, Advances in experimental medicine and biology.

Short chain alcohols activate guanine nucleotide-dependent phosphoinositidase C in turkey erythrocyte membranes.

A. Thomas, E. Rubin, T. A. Rooney, 1989, The Journal of biological chemistry.

Cytosolic free Ca2+ concentration and intracellular calcium distribution of Ca2+-tolerant isolated heart cells.

J. Williamson, A. Thomas, K. Coll, 1983, The Journal of biological chemistry.