R. Kehlenbach

发表

The nuclear pore proteins Nup88/214 and T-cell acute lymphatic leukemia–associated NUP214 fusion proteins regulate Notch signaling

B. Jungnickel, F. Oswald, C. Englert, 2019, The Journal of Biological Chemistry.

In Vivo Labelling of Adenovirus DNA Identifies Chromatin Anchoring and Biphasic Genome Replication

Jean-Michel Lagarde, J. Lagarde, K. Bystricky, 2018, Journal of Virology.

Nuclear Pore Complexes and Nucleocytoplasmic Transport: From Structure to Function to Disease.

B. Fahrenkrog, A. Dickmanns, R. Kehlenbach, 2015, International review of cell and molecular biology.

The SQSTM1-NUP214 fusion protein interacts with Crm1, activates Hoxa and Meis1 genes, and drives leukemogenesis in mice

D. Wechsler, S. Port, R. Kehlenbach, 2020, PloS one.

Defective nuclear import of Tpr in Progeria reflects the Ran sensitivity of large cargo transport

Anindya Dutta, B. Paschal, R. Kehlenbach, 2013, The Journal of cell biology.

Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry*

Henning Urlaub, Samir Karaca, Samir Karaca, 2012, Molecular & Cellular Proteomics.

The Nucleoporin Nup358/RanBP2 Promotes Nuclear Import in a Cargo‐ and Transport Receptor‐Specific Manner

S. Wiemann, U. Rothbauer, R. Kehlenbach, 2012, Traffic.

Ran-dependent docking of importin-β to RanBP2/Nup358 filaments is essential for protein import and cell viability

A. Haeger, J. V. van Deursen, R. Kehlenbach, 2011, The Journal of cell biology.

Analysis of nucleocytoplasmic transport in digitonin-permeabilized cells under different cellular conditions.

N. Imamoto, S. Kose, R. Kehlenbach, 2014, Methods in cell biology.

Proteomic mapping by rapamycin-dependent targeting of APEX2 identifies binding partners of VAPB at the inner nuclear membrane

Christina James, Henning Urlaub, Christof Lenz, 2019, The Journal of Biological Chemistry.

Expression of CD83 Is Regulated by HuR via a Novel cis-Active Coding Region RNA Element*

J. Hauber, M. Dabauvalle, J. Stülke, 2006, Journal of Biological Chemistry.

CRM1-mediated nuclear export: to the pore and beyond.

R. Kehlenbach, Saskia Hutten, 2007, Trends in cell biology.

Nup50, a Nucleoplasmically Oriented Nucleoporin with a Role in Nuclear Protein Export

B. Clurman, N. Arnheim, E. C. Schirmer, 2000, Molecular and Cellular Biology.

Into the basket and beyond: the journey of mRNA through the nuclear pore complex.

Y. Shav-Tal, R. Kehlenbach, Asaf Ashkenazy-Titelman, 2020, The Biochemical journal.

Nucleocytoplasmic Shuttling Factors Including Ran and CRM1 Mediate Nuclear Export of NFAT In Vitro

A. Dickmanns, L. Gerace, R. Kehlenbach, 1998, The Journal of cell biology.

Herpes Simplex Virus ICP27 Protein Directly Interacts with the Nuclear Pore Complex through Nup62, Inhibiting Host Nucleocytoplasmic Transport Pathways

E. C. Schirmer, R. Kehlenbach, A. Tabarraei, 2012, The Journal of Biological Chemistry.

Extensive Identification and In-depth Validation of Importin 13 Cargoes *

R. Kehlenbach, C. Spillner, Kerstin Schmitt, 2018, Molecular & Cellular Proteomics.

The cargo spectrum of nuclear transport receptors.

R. Kehlenbach, Imke Baade, 2019, Current opinion in cell biology.

The Nup358-RanGAP complex is required for efficient importin alpha/beta-dependent nuclear import.

F. Melchior, Annette Flotho, R. Kehlenbach, 2008, Molecular biology of the cell.

The Nup358-RanGAP Complex Is Required for Efﬁcient Importin (cid:1) / (cid:2) -dependent Nuclear Import

F. Melchior, Annette Flotho, R. Kehlenbach, 2008 .

Multiple Importins Function as Nuclear Transport Receptors for the Rev Protein of Human Immunodeficiency Virus Type 1*

J. Hauber, R. Kehlenbach, A. Nath, 2006, Journal of Biological Chemistry.

Analysis of CRM1-Dependent Nuclear Export in Permeabilized Cells.

S. Port, R. Kehlenbach, 2016, Methods in molecular biology.

Combining dehydration, construct optimization and improved data collection to solve the crystal structure of a CRM1-RanGTP-SPN1-Nup214 quaternary nuclear export complex.

M. Weiss, R. Ficner, S. Port, 2015, Acta crystallographica. Section F, Structural biology communications.

Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence

Alessandro Filosa, G. Ravenscroft, N. Laing, 2018, PLoS genetics.

Multiple trimeric G‐proteins on the trans‐Golgi network exert stimulatory and inhibitory effects on secretory vesicle formation.

W. Huttner, F. Barr, R. Kehlenbach, 1992, The EMBO journal.

Biogenesis of Neurosecretory Vesicles

H. Pasolli, W. Huttner, H. Gerdes, 1995 .

Biogenesis of neurosecretory vesicles.

H. Pasolli, W. Huttner, D. Corbeil, 1995, Cold Spring Harbor symposia on quantitative biology.

XL alpha s is a new type of G protein.

W. Huttner, R. Kehlenbach, J. Matthey, 1994, Nature.

GCN5L1 interacts with αTAT1 and RanBP2 to regulate hepatic α-tubulin acetylation and lysosome trafficking

M. Pirooznia, Yong Chen, M. Gucek, 2018, Journal of Cell Science.

Transportin 1 is a major nuclear import receptor of the nitric oxide synthase interacting protein

H. Urlaub, R. Kehlenbach, I. Parfentev, 2023, The Journal of biological chemistry.

Thesis committee members

D. Görlich, H. Urlaub, R. Kehlenbach, 2014 .

Mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence

Alessandro Filosa, G. Ravenscroft, N. Laing, 2018 .

Mutations in nucleoporin NUP88 cause lethal neuromuscular disorder

Alessandro Filosa, G. Ravenscroft, N. Laing, 2018, bioRxiv.

XLαs is a new type of G protein

W. Huttner, R. Kehlenbach, J. Matthey, 1994, Nature.

Post-transcriptional regulation of CD83 expression by AUF1 proteins

J. Hauber, R. Kehlenbach, J. Chemnitz, 2012, Nucleic acids research.

Stimulated expression of mRNAs in activated T cells depends on a functional CRM1 nuclear export pathway.

J. Hauber, M. Frohme, R. Kehlenbach, 2006, Journal of molecular biology.

Notch1 signaling is mediated by importins alpha 3, 4, and 7

R. Depping, C. Kaether, Andreas Krämer, 2010, Cellular and Molecular Life Sciences.

Post-transcriptional regulation of CD 83 expression by AUF 1 proteins

J. Hauber, R. Kehlenbach, J. Chemnitz, 2012 .

Functional Characterization of the HuR:CD83 mRNA Interaction

J. Hauber, R. Kehlenbach, A. Prechtel, 2011, PloS one.

Analysis of Nucleocytoplasmic Trafficking of the HuR Ligand APRIL and Its Influence on CD83 Expression*

J. Hauber, C. Stocking, R. Kehlenbach, 2007, Journal of Biological Chemistry.

Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1

S. Bailer, R. Kehlenbach, Saskia Hutten, 2018, Scientific Reports.

Emery–Dreifuss muscular dystrophy mutations impair TRC40-mediated targeting of emerin to the inner nuclear membrane

B. Schwappach, R. Kehlenbach, Cara Jamieson, 2016, Journal of Cell Science.

Transportin Is a Major Nuclear Import Receptor for c-Fos

R. Kehlenbach, A. Nath, D. Wohlwend, 2006, Journal of Biological Chemistry.

Two overlapping reading frames in a single exon encode interacting proteins—a novel way of gene usage

W. Huttner, R. Kehlenbach, M. Klemke, 2001, The EMBO journal.

Characterization of the extra-large G protein alpha-subunit XLalphas. II. Signal transduction properties.

G. Schultz, H. Pasolli, W. Huttner, 2000, The Journal of biological chemistry.

Characterization of the extra-large G protein alpha-subunit XLalphas. I. Tissue distribution and subcellular localization.

H. Pasolli, W. Huttner, R. Kehlenbach, 2000, The Journal of biological chemistry.

Characterization of the Extra-large G Protein α-Subunit XLαs

H. Pasolli, W. Huttner, R. Kehlenbach, 2000, The Journal of Biological Chemistry.

Characterization of the Extra-large G Protein α-Subunit XLαs

G. Schultz, H. Pasolli, W. Huttner, 2000, The Journal of Biological Chemistry.

CORRECTIONS: XLαs is a new type of G protein

W. Huttner, R. Kehlenbach, J. Matthey, 1995, Nature.

Nup214 Is Required for CRM1-Dependent Nuclear Protein Export In Vivo

R. Kehlenbach, Saskia Hutten, 2006, Molecular and Cellular Biology.

Importin 7 and Nup358 Promote Nuclear Import of the Protein Component of Human Telomerase

R. Kehlenbach, Sarah Wälde, Saskia Hutten, 2014, PloS one.

In vitro analysis of nuclear mRNA export using molecular beacons for target detection.

R. Kehlenbach, 2003, Nucleic acids research.

Human PDCD2L Is an Export Substrate of CRM1 That Associates with 40S Ribosomal Subunit Precursors

F. Boisvert, Danny Bergeron, S. Port, 2016, Molecular and Cellular Biology.

Human PDCD 2 L is an export substrate of CRM 1 that associates with 40 S 3 ribosomal subunit precursors 4 5 6

F. Boisvert, Danny Bergeron, R. Kehlenbach, 2016 .

The RNA-binding protein FUS is chaperoned and imported into the nucleus by a network of import receptors

R. Kehlenbach, Saskia Hutten, D. Dormann, 2021, The Journal of biological chemistry.

Distinct functions of the dual leucine zipper kinase depending on its subcellular localization.

E. Oetjen, K. Maedler, R. Kehlenbach, 2016, Cellular signalling.

The Anti-inflammatory Prostaglandin 15-Deoxy-Δ12,14-PGJ2 Inhibits CRM1-dependent Nuclear Protein Export*

D. Fitzgerald, R. Kehlenbach, C. Spillner, 2010, The Journal of Biological Chemistry.

Probing the Environment of Emerin by Enhanced Ascorbate Peroxidase 2 (APEX2)-Mediated Proximity Labeling

C. Lenz, H. Urlaub, R. Kehlenbach, 2020, Cells.

MD simulations and FRET reveal an environment-sensitive conformational plasticity of importin-β.

H. Grubmüller, J. Enderlein, R. Ficner, 2015, Biophysical journal.

Analysis of nuclear protein import and export in vitro using fluorescent cargoes.

L. Gerace, R. Kehlenbach, 2002, Methods in molecular biology.

Phosphorylation of the Nuclear Transport Machinery Down-regulates Nuclear Protein Import in Vitro *

L. Gerace, R. Kehlenbach, 2000, The Journal of Biological Chemistry.

A Role for RanBP1 in the Release of CRM1 from the Nuclear Pore Complex in a Terminal Step of Nuclear Export

A. Dickmanns, L. Gerace, R. Kehlenbach, 1999, The Journal of cell biology.

Several Phenylalanine-Glycine Motives in the Nucleoporin Nup214 Are Essential for Binding of the Nuclear Export Receptor CRM1*

S. Roloff, R. Kehlenbach, C. Spillner, 2012, The Journal of Biological Chemistry.

The nucleoporin-like protein NLP1 (hCG1) promotes CRM1-dependent nuclear protein export

R. Kehlenbach, C. Spillner, Inga Waldmann, 2012, Journal of Cell Science.

Sequestosome 1 Is Part of the Interaction Network of VAPB

C. Lenz, H. Urlaub, R. Kehlenbach, 2021, International journal of molecular sciences.

Novel approaches for the identification of nuclear transport receptor substrates.

M. Kimura, Samir Karaca, N. Imamoto, 2014, Methods in cell biology.

The Part and the Whole: functions of nucleoporins in nucleocytoplasmic transport.

R. Kehlenbach, Sarah Wälde, 2010, Trends in cell biology.

The Interactome of the VAP Family of Proteins: An Overview

R. Kehlenbach, C. James, 2021, Cells.

CRM1 Promotes Capsid Disassembly and Nuclear Envelope Translocation of Adenovirus Independently of Its Export Function

S. Port, H. Wodrich, R. Kehlenbach, 2021, Journal of virology.

Nup358 and Transportin 1 Cooperate in Adenoviral Genome Import

Noémie Pied, H. Wodrich, R. Kehlenbach, 2020, Journal of Virology.

Identification and functional dissection of localization signals within ataxin-3

O. Riess, R. Kehlenbach, P. Antony, 2009, Neurobiology of Disease.

Interaction of nucleoporins with nuclear transport receptors: a structural perspective

P. Neumann, R. Ficner, A. Dickmanns, 2023, Biological chemistry.

Targeting of LRRC59 to the Endoplasmic Reticulum and the Inner Nuclear Membrane

R. Kehlenbach, Marina Blenski, Ralph H Kehlenbach, 2019, International journal of molecular sciences.

Resolution doubling in fluorescence microscopy with confocal spinning-disk image scanning microscopy

Christoph Pieper, Jörg Großhans, Jörg Enderlein, 2013, Proceedings of the National Academy of Sciences.

Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export.

H. Urlaub, R. Ficner, S. Port, 2015, Cell reports.

The nuclear pore component Nup358 promotes transportin-dependent nuclear import

J. Hauber, R. Kehlenbach, Sarah Wälde, 2009, Journal of Cell Science.

Three-Dimensional Reconstruction of Nuclear Envelope Architecture Using Dual-Color Metal-Induced Energy Transfer Imaging.

J. Enderlein, R. Kehlenbach, A. Chizhik, 2017, ACS nano.

Dual-Color Metal-Induced Energy Transfer (MIET) Imaging for Three-Dimensional Reconstruction of Nuclear Envelope Architecture.

J. Enderlein, R. Kehlenbach, A. Chizhik, 2020, Methods in molecular biology.

Stimulation of Nuclear Export and Inhibition of Nuclear Import by a Ran Mutant Deficient in Binding to Ran-binding Protein 1*

L. Gerace, R. Kehlenbach, J. Becker, 2001, The Journal of Biological Chemistry.

The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A)+ RNA Export*

B. Fahrenkrog, S. Port, C. Kaether, 2016, The Journal of Biological Chemistry.

Phosphorylation-dependent interactions of VAPB and ELYS contribute to the temporal progression of mitosis

H. Urlaub, R. Kehlenbach, U. Möller, 2023, bioRxiv.

Structural and Functional C haracterization of CRM 1-Nup 214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export Graphical

H. Urlaub, R. Ficner, S. Port, 2022 .

A nuclear export sequence promotes CRM1-dependent targeting of the nucleoporin Nup214 to the nuclear pore complex

S. Port, M. Hamed, R. Kehlenbach, 2021, Journal of Cell Science.

Acetylcholinesterase and butyrylcholinesterase genes coamplify in primary ovarian carcinomas.

H. Soreq, R. Kehlenbach, G. Malinger, 1990, The Journal of clinical investigation.

Nuclear Import of c-Jun Is Mediated by Multiple Transport Receptors *

R. Kehlenbach, Sarah Wälde, Inga Waldmann, 2007, Journal of Biological Chemistry.