R. Crystal

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Specific binding of the adenovirus capsid to the nuclear envelope.

P. Leopold, J. Wisnivesky, R. Crystal, 1999, Human gene therapy.

Free cholesterol enhances adenoviral vector gene transfer and expression in CAR-deficient cells.

N. Hackett, S. Worgall, Kostas Kostarelos, 2000, Molecular therapy : the journal of the American Society of Gene Therapy.

Adenovirus-mediated expression of melanoma antigen gp75 as immunotherapy for metastatic melanoma

E. Hirschowitz, W. Song, P. Leopold, 1998, Gene Therapy.

Role of alveolar macrophages in rapid elimination of adenovirus vectors administered to the epithelial surface of the respiratory tract.

G. Wolff, S. Worgall, P. Leopold, 1997, Human gene therapy.

Variation in adenovirus receptor expression and adenovirus vector-mediated transgene expression at defined stages of the cell cycle.

R. Crystal, M. Seidman, S. Worgall, 2001, Molecular therapy : the journal of the American Society of Gene Therapy.

Cytotoxic T lymphocyte responses to proteins encoded by heterologous transgenes transferred in vivo by adenoviral vectors.

W. Song, R. Crystal, P. Traktman, 1997, Human gene therapy.

Phase I study of direct administration of a replication deficient adenovirus vector containing the E. coli cytosine deaminase gene to metastatic colon carcinoma of the liver in association with the oral administration of the pro-drug 5-fluorocytosine.

C. Henschke, D. Yankelevitz, N. Kemeny, 1997, Human gene therapy.

al-Antitrypsin NullbL.d . An al-Antitrypsin Deficiency Allele Caused by Deletion of All al-Antitrypsin Coding Exons

R. Crystal, H. Takahashi, 2006 .

Adenovirus-mediated gene transfer of dopamine D2 receptor cDNA into rat striatum.

D. Ingram, S. Kato, G. Roth, 1995, Brain research. Molecular brain research.

Adenoviral-vector-mediated gene transfer to dendritic cells.

W. Song, R. Crystal, Wenru Song, 2001, Methods in molecular medicine.

Cellular immune responses of healthy individuals to intradermal administration of an E1-E3- adenovirus gene transfer vector.

B. Harvey, S. Worgall, P. Leopold, 1999, Human gene therapy.

A phase 1 study, in cystic fibrosis patients, of the safety, toxicity, and biological efficacy of a single administration of a replication deficient, recombinant adenovirus carrying the cDNA of the normal cystic fibrosis transmembrane conductance regulator gene in the lung.

S. Brody, C. Chu, J. Hay, 1995, Human gene therapy.

Enhanced liver uptake of opsonized red blood cells after in vivo transfer of FcgammaRIIA cDNA to the liver.

M. K. Kim, S. Worgall, P. Leopold, 1999, Blood.

The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro

E. Alton, F. Sorgi, L. Huang, 1998, Gene Therapy.

Enhanced Expression of the Glutamate Decarboxylase 67 in Human Small Airway Epithelium in Response to Cigarette Smoking.

Guoqing Wang, R. Crystal, Rui Wang, 2009, ATS 2009.

Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor.

N. Hackett, J. Bergelson, S. Worgall, 1999, American journal of respiratory cell and molecular biology.

Transfer of a gene encoding the anticandidal protein histatin 3 to salivary glands.

R. Crystal, B. Baum, B. O'Connell, 1996, Human gene therapy.

Direct in vivo adenovirus-mediated gene transfer to salivary glands.

R. Crystal, B. Baum, B. O'Connell, 1994, The American journal of physiology.

Regional ‘pro-drug’ gene therapy: intravenous administration of an adenoviral vector expressing the E. coli cytosine deaminase gene and systemic administration of 5-fluorocytosine suppresses growth of hepatic metastasis of colon carcinoma

R. Crystal, N. Hackett, S. Worgall, 1998, Gene Therapy.

Construction of an adenovirus type 7a E1A- vector

D. Brough, R. Crystal, E. Falck-Pedersen, 1997, Journal of virology.

Limited heterogeneity of biased T‐cell receptor Vβ gene usage in lung but not blood T cells in active pulmonary sarcoidosis

R. Crystal, R. Silver, D. Moller, 1996, Immunology.

Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ

B. Harvey, W. Song, G. Wolff, 1997, Journal of virology.

Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration.

R. Crystal, G. Wolff, S. Worgall, 1997, Human gene therapy.

AAV2-mediated CLN2 gene transfer to rodent and non-human primate brain results in long-term TPP-I expression compatible with therapy for LINCL

N. Hackett, P. Leopold, R. Crystal, 2005, Gene Therapy.

Fluorescent virions: dynamic tracking of the pathway of adenoviral gene transfer vectors in living cells.

N. Hackett, S. Worgall, P. Leopold, 1998, Human gene therapy.

Ability of a chimeric cAMP-responsive promoter to confer pharmacologic control of CFTR cDNA expression and cAMP-mediated Cl− secretion

M. Suzuki, R. Crystal, R. Singh, 1997, Gene Therapy.

Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog.

R. Crystal, N. Sato, P. Leopold, 1999, The Journal of clinical investigation.

Persistent, antigen-specific, therapeutic antitumor immunity by dendritic cells genetically modified with an adenoviral vector to express a model tumor antigen

W. Song, R. Crystal, H. Kong, 2000, Gene Therapy.

Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor.

R. Crystal, N. Hackett, W. Song, 1998, Human gene therapy.

Glutathione S-transferase copy number variation alters lung gene expression

J. Mezey, L. Omberg, N. Hackett, 2011, European Respiratory Journal.

Augmentation of pulmonary host defense against Pseudomonas by FcgammaRIIA cDNA transfer to the respiratory epithelium.

M. K. Kim, S. Worgall, R. Crystal, 1999, The Journal of clinical investigation.

"Sero-switch" adenovirus-mediated in vivo gene transfer: circumvention of anti-adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype.

B. Harvey, G. Wolff, R. Crystal, 1996, Human gene therapy.

Dynein- and microtubule-mediated translocation of adenovirus serotype 5 occurs after endosomal lysis.

G. Kreitzer, P. Leopold, R. Crystal, 2000, Human gene therapy.

Effect of adenovirus-mediated expression of Sonic hedgehog gene on hair regrowth in mice with chemotherapy-induced alopecia.

R. Crystal, N. Sato, P. Leopold, 2001, Journal of the National Cancer Institute.

Evaluation of repeat administration of a replication deficient, recombinant adenovirus containing the normal cystic fibrosis transmembrane conductance regulator cDNA to the airways of individuals with cystic fibrosis.

C. Henschke, B. Harvey, R. Crystal, 1995, Human gene therapy.

Z-type alpha 1-antitrypsin is less competent than M1-type alpha 1-antitrypsin as an inhibitor of neutrophil elastase.

R. Crystal, R. Crystal, R. Hubbard, 1987, The Journal of clinical investigation.