J. Manischewitz

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A Potent Germline-like Human Monoclonal Antibody Targets a pH-Sensitive Epitope on H7N9 Influenza Hemagglutinin

Wei Li, D. Dimitrov, X. Ji, 2017, Cell Host & Microbe.

Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin

Surender Khurana, Hana Golding, Hua-Xin Liao, 2011, Proceedings of the National Academy of Sciences.

Antibody-dependent enhancement of influenza disease promoted by increase in hemagglutinin stem flexibility and virus fusion kinetics

H. Turner, A. Ward, S. Khurana, 2019, Proceedings of the National Academy of Sciences.

Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody

Thomas B. Kepler, Huafeng Xu, Surender Khurana, 2012, Proceedings of the National Academy of Sciences.

Brucella abortus conjugated with a gp120 or V3 loop peptide derived from human immunodeficiency virus (HIV) type 1 induces neutralizing anti-HIV antibodies, and the V3-B. abortus conjugate is effective even after CD4+ T-cell depletion

N. Blyveis, B. Golding, J. Inman, 1995, Journal of virology.

H5 N-terminal β sheet promotes oligomerization of H7-HA1 that induces better antibody affinity maturation and enhanced protection against H7N7 and H7N9 viruses compared to inactivated influenza vaccine.

S. Khurana, J. Manischewitz, L. King, 2014, Vaccine.

Common epitope in human immunodeficiency virus (HIV) I-GP41 and HLA class II elicits immunosuppressive autoantibodies capable of contributing to immune dysfunction in HIV I-infected individuals.

M. Clerici, B. Golding, G. Shearer, 1989, The Journal of clinical investigation.

Comparative virulence and immunogenicity of the Towne strain and a nonattenuated strain of cytomegalovirus.

S. Plotkin, J. Manischewitz, J. Epstein, 1984, Annals of internal medicine.

Smallpox vaccine–induced antibodies are necessary and sufficient for protection against monkeypox virus

K. Reimann, M. Bray, D. Scott, 2005, Nature Medicine.

The phorbol ester phorbol myristate acetate inhibits human immunodeficiency virus type 1 envelope-mediated fusion by modulating an accessory component(s) in CD4-expressing cells

D. Dimitrov, R. Blumenthal, J. Manischewitz, 1994, Journal of virology.

Intestinal infections in patients with the acquired immunodeficiency syndrome (AIDS). Etiology and response to therapy.

A. Fauci, H. Masur, H. Lane, 1988, Annals of internal medicine.

from lethality by reducing viral loads in the upper respiratory tract and internal organs. 2

Senta M Kapnick, J. Manischewitz, L. King, 2011 .

Passive Immunotherapies Protect WRvFire and IHD-J-Luc Vaccinia Virus-Infected Mice from Lethality by Reducing Viral Loads in the Upper Respiratory Tract and Internal Organs

Senta M Kapnick, J. Manischewitz, L. King, 2011, Journal of Virology.

Smallpox vaccine does not protect macaques with AIDS from a lethal monkeypox virus challenge.

D. Venzon, Mark G. Lewis, M. Bray, 2005, The Journal of infectious diseases.

Recombinant HA1 produced in E. coli forms functional oligomers and generates strain-specific SRID potency antibodies for pandemic influenza vaccines.

A. Steven, J. Fontana, C. Larkin, 2011, Vaccine.

Vaccines with MF59 Adjuvant Expand the Antibody Repertoire to Target Protective Sites of Pandemic Avian H5N1 Influenza Virus

R. Rappuoli, M. Rock, K. Edwards, 2010, Science Translational Medicine.

Lack of clinical utility of bronchoalveolar lavage cultures for cytomegalovirus in HIV infection.

F. Ognibene, J. Shelhamer, W. Travis, 1997, American journal of respiratory and critical care medicine.

Lack of Clinical Utility of Cytomegalovirus Blood and Urine Cultures in Patients with HIV Infection

D. O'neill, M. Baseler, M. Polis, 1993, Annals of Internal Medicine.

DNA priming prior to inactivated influenza A(H5N1) vaccination expands the antibody epitope repertoire and increases affinity maturation in a boost-interval-dependent manner in adults.

B. Graham, J. Ledgerwood, S. Khurana, 2013, The Journal of infectious diseases.

Oral Priming with Replicating Adenovirus Serotype 4 Followed by Subunit H5N1 Vaccine Boost Promotes Antibody Affinity Maturation and Expands H5N1 Cross-Clade Neutralization

S. Khurana, J. Manischewitz, L. King, 2015, PloS one.

A live attenuated influenza A(H5N1) vaccine induces long-term immunity in the absence of a primary antibody response.

R. Karron, D. Follmann, K. Subbarao, 2014, The Journal of infectious diseases.

Antigenic Fingerprinting of H5N1 Avian Influenza Using Convalescent Sera and Monoclonal Antibodies Reveals Potential Vaccine and Diagnostic Targets

K. Subbarao, F. Sallusto, A. Lanzavecchia, 2009, PLoS medicine.

Properly Folded Bacterially Expressed H1N1 Hemagglutinin Globular Head and Ectodomain Vaccines Protect Ferrets against H1N1 Pandemic Influenza Virus

S. Khurana, J. Manischewitz, L. King, 2010, PloS one.

Novel antibody-independent receptor-binding SPR-based assay for rapid measurement of influenza vaccine potency.

S. Khurana, J. Manischewitz, L. King, 2014, Vaccine.

Durable neutralizing antibodies after remote smallpox vaccination among adults with and without HIV infection

J. Manischewitz, L. King, H. Golding, 2007, AIDS.

Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses

J. P. McCoy, F. Marincola, Manikandan Narayanan, 2014, Cell.

Kinetics of soluble CD4 binding to cells expressing human immunodeficiency virus type 1 envelope glycoprotein

D. Dimitrov, R. Blumenthal, J. Manischewitz, 1992, Journal of virology.

Development of a novel vaccinia-neutralization assay based on reporter-gene expression.

T. Monath, J. Shiloach, D. Scott, 2003, The Journal of infectious diseases.

H5N1 Virus-Like Particle Vaccine Elicits Cross-Reactive Neutralizing Antibodies That Preferentially Bind to the Oligomeric Form of Influenza Virus Hemagglutinin in Humans

G. Glenn, S. Khurana, J. Manischewitz, 2011, Journal of Virology.

A Rapid Flp-In System for Expression of Secreted H5N1 Influenza Hemagglutinin Vaccine Immunogen in Mammalian Cells

S. Khurana, J. Manischewitz, L. King, 2011, PloS one.

Human Peripheral Blood T Cells, Monocytes, and Macrophages Secrete Macrophage Inflammatory Proteins 1α and 1β following Stimulation with Heat-Inactivated Brucella abortus

B. Golding, J. Manischewitz, L. King, 2001, Infection and Immunity.

Interferong and interleukin 6 modulate the susceptibility of macrophages to human immunodeficiency virus type 1 infection

J. Manischewitz, L. King, H. Golding, 2000 .

Clinical and immunological comparison of smallpox vaccine administered to the outer versus the inner upper arms of vaccinia-naive adults.

R. Topolski, J. Manischewitz, L. King, 2006, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

T Cells Mice Reconstituted with Vaccinia Virus in Normal Mice and in ST-246 on Dissemination of IHD-J-Luc Effects of Postchallenge Administration of

R. Jordan, J. Manischewitz, L. King, 2014 .

Effects of Postchallenge Administration of ST-246 on Dissemination of IHD-J-Luc Vaccinia Virus in Normal Mice and in Immune-Deficient Mice Reconstituted with T Cells

R. Jordan, J. Manischewitz, L. King, 2013, Journal of Virology.

Intravenous immunoglobulin products contain neutralizing antibodies to vaccinia

D. Scott, M. Mikolajczyk, J. Manischewitz, 2004, Vox sanguinis.

Enhanced immunogenicity and protective effect conferred by vaccination with combinations of modified vaccinia virus Ankara and licensed smallpox vaccine Dryvax in a mouse model.

A. Mayer, J. Manischewitz, L. King, 2005, Virology.

A practical influenza neutralization assay to simultaneously quantify hemagglutinin and neuraminidase-inhibiting antibody responses.

M. Eichelberger, J. Manischewitz, L. King, 2010, Vaccine.

CXCR4 heterogeneity in primary cells: possible role of ubiquitination

E. Petricoin, J. Manischewitz, L. King, 2002, Journal of leukocyte biology.

Involvement of natural killer cells in the pathogenesis of murine cytomegalovirus interstitial pneumonitis and the immune response to infection.

J. Manischewitz, G. Quinnan,, N. Kirmani, 1982, The Journal of general virology.

Chemical and Biological Characterization of Natural Human Lymphoblastoid Interferon Alphas

K. Zoon, J. Manischewitz, J. Enterline, 1987 .

Enhancement of human immunodeficiency virus type 1 envelope-mediated fusion by a CD4-gp120 complex-specific monoclonal antibody

C. Broder, D. Dimitrov, J. Gershoni, 1997, Journal of virology.

Cytomegalovirus induction of tumor necrosis factor-alpha by human monocytes and mucosal macrophages.

M. Raffeld, P. D. Smith, S. Wahl, 1992, The Journal of clinical investigation.

Inhibition of HIV-1 infection by a CCR5-binding cyclophilin from Toxoplasma gondii.

J. Andersen, A. Sher, J. Aliberti, 2003, Blood.

Mechanisms of T-cell functional deficiency in the acquired immunodeficiency syndrome.

J. Manischewitz, J. Epstein, J. Siegel, 1985, Annals of internal medicine.

Increased CXCR4‐dependent HIV‐1 fusion in activated T cells: role of CD4/CXCR4 association

J. Manischewitz, H. Golding, M. Zaitseva, 2005 .

HLA-restricted cytotoxic T lymphocyte and nonthymic cytotoxic lymphocyte responses to cytomegalovirus infection of bone marrow transplant recipients.

J. Manischewitz, A. Rook, G. Quinnan,, 1981, Journal of immunology.

Brucella abortus as a potential vaccine candidate: induction of interleukin-12 secretion and enhanced B7.1 and B7.2 and intercellular adhesion molecule 1 surface expression in elutriated human monocytes stimulated by heat-inactivated B. abortus

B. Golding, J. Manischewitz, H. Golding, 1996, Infection and immunity.

heat-inactivated B . abortus . elutriated human monocytes stimulated by adhesion molecule 1 surface expression in and enhanced B 7 . 1 and B 7 . 2 and intercellular secretioncandidate : induction of interleukin-12 Brucella abortus as a potential vaccine

B. Golding, J. Manischewitz, H. Golding, 1996 .

Study of viral replication in HIV-1-infected CEM T-cell subclones which are reduced in their ability to form syncytia.

I. Hewlett, J. Manischewitz, H. Golding, 1992, AIDS research and human retroviruses.

Interleukin-2 enhances the depressed natural killer and cytomegalovirus-specific cytotoxic activities of lymphocytes from patients with the acquired immune deficiency syndrome.

A. Fauci, H. Masur, H. Lane, 1983, The Journal of clinical investigation.

Anticytomegaloviral activity and safety of cidofovir in patients with human immunodeficiency virus infection and cytomegalovirus viruria

R. Davey, J. Kovacs, M. Polis, 1995, Antimicrobial agents and chemotherapy.

Cytomegalovirus-specific cytotoxicity mediated by non-T lymphocytes from peripheral blood of normal volunteers

J. Manischewitz, G. Quinnan,, K. Mittal, 1981, Infection and immunity.

Cytotoxic lymphocytes and antibody-dependent complement-mediated cytotoxicity induced by administration of influenza vaccine

R. Armstrong, F. Ennis, G. Butchko, 1980, Infection and immunity.

Application of Bioluminescence Imaging to the Prediction of Lethality in Vaccinia Virus-Infected Mice

Senta M Kapnick, J. Manischewitz, L. King, 2009, Journal of Virology.

Antibodies to the A27 protein of vaccinia virus neutralize and protect against infection but represent a minor component of Dryvax vaccine--induced immunity.

I. Berkower, J. Manischewitz, H. Golding, 2007, The Journal of infectious diseases.

Subunit Recombinant Vaccine Protects against Monkeypox1

D. Venzon, J. Héraud, M. Bray, 2006, The Journal of Immunology.

Herpesvirus infections in the acquired immune deficiency syndrome.

H. Masur, J. Parrillo, M. Parker, 1984, JAMA.

Importance of Cytotoxic Lymphocytes During Cytomegalovirus Infection in Renal Transplant Recipients

J. Manischewitz, A. Rook, G. Quinnan,, 1984 .

Correlation between kinetics of soluble CD4 interactions with HIV‐1-Env‐expressing cells and inhibition of syncytia formation: implications for mechanisms of cell fusion and therapy for AIDS

D. Dimitrov, R. Blumenthal, J. Manischewitz, 1992, AIDS.

Kinetics ofSoluble CD4Binding toCells Expressing Human Immunodeficiency VirusType1Envelope Glycoprotein

R. Blumenthal, J. Manischewitz, H. Golding, 1992 .

Death in the AIDS patient: role of cytomegalovirus.

D. Longo, A. Fauci, H. Lane, 1983, The New England journal of medicine.

Electroporation of Synthetic DNA Antigens Offers Protection in Nonhuman Primates Challenged with Highly Pathogenic Avian Influenza Virus

D. Weiner, Jian Yan, Mark G. Lewis, 2009, Journal of Virology.

Effect of 9-(1,3-dihydroxy-2-propoxymethyl) guanine on serious cytomegalovirus disease in eight immunosuppressed homosexual men.

H. Masur, H. Lane, R. Nussenblatt, 1986, Annals of internal medicine.

Treatment of cytomegalovirus retinitis with dihydroxy propoxymethyl guanine.

E. Gelmann, A. Fauci, H. Masur, 1986, American journal of ophthalmology.

Adenovirus colitis in the acquired immunodeficiency syndrome.

J. Orenstein, P. D. Smith, J. Manischewitz, 1991, Gastroenterology.

Esophageal disease in AIDS is associated with pathologic processes rather than mucosal human immunodeficiency virus type 1.

H. Masur, P. D. Smith, J. Manischewitz, 1993, The Journal of infectious diseases.

Expression and function of CCR5 and CXCR4 on human Langerhans cells and macrophages: Implications for HIV primary infection

A. Blauvelt, J. Manischewitz, H. Golding, 1997, Nature Medicine.

Synergistic effect of ganciclovir and foscarnet on cytomegalovirus replication in vitro

J. Manischewitz, A. Wittek, G. Quinnan,, 1990, Antimicrobial Agents and Chemotherapy.

Importance of cytotoxic lymphocytes during cytomegalovirus infection in renal transplant recipients.

J. Manischewitz, A. Rook, G. Quinnan,, 1984, The American journal of medicine.

Cytotoxic t cells in cytomegalovirus infection: HLA-restricted T-lymphocyte and non-T-lymphocyte cytotoxic responses correlate with recovery from cytomegalovirus infection in bone-marrow-transplant recipients.

J. Manischewitz, A. Rook, G. Moreschi, 1982, The New England journal of medicine.

HLA-restricted cytotoxic T lymphocytes are an early immune response and important defense mechanism in cytomegalovirus infections.

J. Manischewitz, A. Rook, G. Quinnan,, 1984, Reviews of infectious diseases.

Discontinuation of anticytomegalovirus therapy in patients with HIV infection and cytomegalovirus retinitis.

J. Metcalf, R. Davey, J. Kovacs, 1999, JAMA.

Salmonella typhimurium enteritis and bacteremia in the acquired immunodeficiency syndrome.

E. Gelmann, P. D. Smith, J. Manischewitz, 1985, Annals of internal medicine.

Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses

Yuri Kotliarov, Wei Wang, Manikandan Narayanan, 2014, Cell.

Genetically determined resistance to lethal murine cytomegalovirus infection is mediated by interferon-dependent and -independent restriction of virus replication

J. Manischewitz, G. Quinnan,, 1987, Journal of virology.

A phase I trial of recombinant human interferon-γ in patients with Kaposi's sarcoma and the acquired immunodeficiency syndrome (AIDS)

R. Davey, A. Fauci, H. Masur, 1989, Journal of Clinical Immunology.

Interleukin 2 enhances the natural killer cell activity of acquired immunodeficiency syndrome patients through a gamma-interferon-independent mechanism.

A. Fauci, H. Masur, H. Lane, 1985, Journal of immunology.

Phorbol ester-induced down modulation of tailless CD4 receptors requires prior binding of gp120 and suggests a role for accessory molecules

C. Broder, J. Robinson, D. Dimitrov, 1995, Journal of virology.

Selective defects in cytomegalovirus- and mitogen-induced lymphocyte proliferation and interferon release in patients with acquired immunodeficiency syndrome.

H. Masur, J. Djeu, J. Manischewitz, 1985, The Journal of infectious diseases.

Patients with MS under daclizumab therapy mount normal immune responses to influenza vaccination

Hana Golding, Bibiana Bielekova, Andrew Blake, 2016, Neurology: Neuroimmunology & Neuroinflammation.

Influenza vaccination reveals sex dimorphic imprints of prior mild COVID-19

W. Lau, R. Apps, J. Tsang, 2023, Nature.

Influenza vaccination and single cell multiomics reveal sex dimorphic immune imprints of prior mild COVID-19

W. Lau, R. Apps, J. Tsang, 2022, medRxiv.

Modeling a safer smallpox vaccination regimen, for human immunodeficiency virus type 1-infected patients, in immunocompromised macaques.

J. Berzofsky, B. Moss, D. Venzon, 2003, The Journal of infectious diseases.

Subunit Recombinant Vaccine Protects against Monkeypox

D. Venzon, J. Héraud, M. Bray, 2006 .

against Monkeypox Subunit Recombinant Vaccine Protects

D. Venzon, J. Héraud, M. Bray, 2006 .

Viral infections and cell-mediated immunity in immunodeficient homosexual men with Kaposi's sarcoma treated with human lymphoblastoid interferon.

E. Gelmann, J. Djeu, J. Manischewitz, 1985, The Journal of infectious diseases.

Cytomegalovirus-specific Cytotoxic Activities of Lymphocytes from Patients with the Acquired Immune Deficiency Syndrome

A. Fauci, H. Masur, J. Djeu, 1983 .

Impaired B cell immunity in acute myeloid leukemia patients after chemotherapy

M. Goswami, C. Hourigan, B. Smith, 2017, Journal of Translational Medicine.

PREVALENCE, CLINICAL MANIFESTATIONS, AND IMMUNOLOGY OF HERPESVIRUS INFECTIONS IN THE ACQUIRED IMMUNODEFICIENCY SYNDROME

H. Masur, J. Djeu, J. Manischewitz, 1984, Annals of the New York Academy of Sciences.

Humans with chronic granulomatous disease maintain humoral immunologic memory despite low frequencies of circulating memory B cells.

T. Chun, A. Fauci, S. Khurana, 2012, Blood.

Reduction of endotoxin levels in influenza virus vaccines by barium sulfate adsorption-elution.

F. Ennis, H. D. Hochstein, J. Manischewitz, 1975, Applied microbiology.

Cell fusion mediated by interaction of a hybrid CD4.CD8 molecule with the human immunodeficiency virus type 1 envelope glycoprotein does occur after a long lag time

D. Dimitrov, D. Littman, R. Blumenthal, 1993, Journal of virology.

Vaccine-Induced Anti-HA2 Antibodies Promote Virus Fusion and Enhance Influenza Virus Respiratory Disease

A. Vincent, P. Gauger, S. Khurana, 2013, Science Translational Medicine.

Bacterial HA1 Vaccine against Pandemic H5N1 Influenza Virus: Evidence of Oligomerization, Hemagglutination, and Cross-Protective Immunity in Ferrets

S. Khurana, J. Manischewitz, L. King, 2010, Journal of Virology.

Interferon γ and interleukin 6 modulate the susceptibility of macrophages to human immunodeficiency virus type 1 infection

J. Manischewitz, L. King, H. Golding, 2000 .

AS03-adjuvanted H5N1 vaccine promotes antibody diversity and affinity maturation, NAI titers, cross-clade H5N1 neutralization, but not H1N1 cross-subtype neutralization

R. Germain, N. Young, J. Tsang, 2018, npj Vaccines.

Deficient, HLA-restricted, cytomegalovirus-specific cytotoxic T cells and natural killer cells in patients with the acquired immunodeficiency syndrome.

E. Gelmann, H. Masur, J. Manischewitz, 1985, The Journal of infectious diseases.

Production of a novel antigen by conjugation of HIV-1 to Brucella abortus: studies of immunogenicity, isotype analysis, T-cell dependency, and syncytia inhibition.

B. Golding, J. Manischewitz, H. Golding, 1991, AIDS research and human retroviruses.

Impaired B cell immunity in acute myeloid leukemia patients after chemotherapy

M. Goswami, C. Hourigan, B. Smith, 2017, Journal of Translational Medicine.

Comparative Evaluation of the Immune Responses and Protection Engendered by LC16m8 and Dryvax Smallpox Vaccines in a Mouse Model

J. Manischewitz, L. King, H. Golding, 2009, Clinical and Vaccine Immunology.

Brucella abortus conjugated with a peptide derived from the V3 loop of human immunodeficiency virus (HIV) type 1 induces HIV-specific cytotoxic T-cell responses in normal and in CD4+ cell-depleted BALB/c mice

B. Golding, J. Inman, J. Manischewitz, 1996, Journal of virology.

Increased CXCR4-dependent HIV-1 Fusion in Activated T Cells: Role of CD4/CXCR4 Association

J. Manischewitz, H. Golding, M. Zaitseva, 2005, Retrovirology.

Coreceptor Competition for Association with CD4 May Change the Susceptibility of Human Cells to Infection with T-Tropic and Macrophagetropic Isolates of Human Immunodeficiency Virus Type 1

Hana Golding, Howard Mostowski, Hong Chen, 2000, Journal of Virology.

AS03-adjuvanted H5N1 vaccine promotes antibody diversity and affinity maturation, NAI titers, cross-clade H5N1 neutralization, but not H1N1 cross-subtype neutralization

R. Germain, N. Young, J. Tsang, 2018, npj Vaccines.

Chemically selected subclones of the CEM cell line demonstrate resistance to HIV-1 infection resulting from a selective loss of NF-kappa B DNA binding proteins.

V. Bours, J. Manischewitz, H. Golding, 1994, Journal of immunology.

Dissection of Human Immunodeficiency Virus Type 1 Entry with Neutralizing Antibodies to gp41 Fusion Intermediates

S. Zolla-Pazner, M. Gorny, D. Dimitrov, 2002, Journal of Virology.

Quantification of Humoral Immune Response to Influenza Vaccination in MDS

P. Srivastava, J. Manischewitz, L. King, 2019, Blood.

Reduced susceptibility to HIV-1 infection of ethyl-methanesulfonate-treated CEM subclones correlates with a blockade in their protein kinase C signaling pathway.

J. Manischewitz, H. Golding, J. Qian, 1992, Journal of Immunology.

Chemically induced CD4 mutants of a human T cell line. Evidence for dissociation between binding of HIV I envelope and susceptibility to HIV I infection and syncytia formation.

J. Hooley, J. Manischewitz, H. Golding, 1990, Journal of Immunology.

Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses

F. Marincola, Manikandan Narayanan, D. Chaussabel, 2014, Cell.

Vaccines with MF59 Adjuvant Expand the Antibody Repertoire to Target Protective Sites of Pandemic Avian H5N1 Influenza Virus

R. Rappuoli, M. Rock, K. Edwards, 2010, Science Translational Medicine.

Virus-specific cytotoxic lymphocyte responses are predictive of the outcome of cytomegalovirus infection of renal transplant recipients.

J. Manischewitz, J. Burdick, J. Siegel, 1984, Transplantation proceedings.

Reduction of Endotoxin Levels in Influenza Virus Vaccines by Barium Sulfate Adsorption-Elution

F. Ennis, H. D. Hochstein, J. Manischewitz, 1975 .