H. Takaku

发表

Characterization of baculovirus Autographa californica multiple nuclear polyhedrosis virus infection in mammalian cells.

M. Kitajima, H. Hamazaki, N. Miyano-Kurosaki, 2006, Biochemical and biophysical research communications.

Lipoprotein lipase and hepatic triglyceride lipase reduce the infectivity of hepatitis C virus (HCV) through their catalytic activities on HCV-associated lipoproteins.

Y. Shimizu, K. Shimotohno, A. Kato, 2010, Virology.

A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity

Naoki Yamamoto, Yuetsu Tanaka, Hiroshi Takaku, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Baculovirus Induces an Innate Immune Response and Confers Protection from Lethal Influenza Virus Infection in Mice1

Y. Matsuura, T. Abe, H. Hamazaki, 2003, The Journal of Immunology.

Involvement of the Toll-Like Receptor 9 Signaling Pathway in the Induction of Innate Immunity by Baculovirus

S. Akira, Y. Matsuura, T. Abe, 2005, Journal of Virology.

Suppression of HCV RNA replication by baculovirus-mediated shRNA expression.

K. Shimotohno, N. Miyano-Kurosaki, H. Takaku, 2005 .

LENTIVIRAL-MEDIATED DELIVERY OF COMBINED HIV-1 DECOY TAR AND Vif siRNA AS A SINGLE 1RNA MOLECULE THAT CLEAVES TO INHIBIT HIV-1 IN TRANSDUCED CELLS

N. Miyano-Kurosaki, H. Takaku, N. Yamamoto, 2005, Nucleosides, nucleotides & nucleic acids.

Induction of antitumor immunity against mouse carcinoma by baculovirus-infected dendritic cells

Tomoyuki Suzuki, M. Kitajima, H. Takaku, 2010, Cellular and Molecular Immunology.

Baculovirus activates murine dendritic cells and induces non-specific NK cell and T cell immune responses.

Tomoyuki Suzuki, M. Kitajima, H. Takaku, 2010, Cellular immunology.

Stable replication of the EBNA1/OriP-mediated baculovirus vector and its application to anti-HCV gene therapy

Tomoyuki Suzuki, H. Takaku, M. O. Chang, 2009, Virology Journal.

Induction of natural killer cell-dependent antitumor immunity by the Autographa californica multiple nuclear polyhedrosis virus.

M. Taniguchi, T. Nakayama, T. Abe, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

Induction of Antitumor Acquired Immunity by Baculovirus Autographa californica Multiple Nuclear Polyhedrosis Virus Infection in Mice

M. Kitajima, H. Takaku, 2007, Clinical and Vaccine Immunology.

Solid phase synthesis of the 3′-terminal nonadecaribonucleoside octadecaphosphate sequence of yeast alanine transfer ribonucleic acid

T. S. Rao, H. Takaku, C. Reese, 1987 .

Inhibition of hepatitis C virus RNA replication by short hairpin RNA synthesized by T7 RNA polymerase in hepatitis C virus subgenomic replicons.

K. Shimotohno, H. Hamazaki, N. Miyano-Kurosaki, 2006, Biochemical and biophysical research communications.

Hepatitis C Virus Infection Induces Inflammatory Cytokines and Chemokines Mediated by the Cross Talk between Hepatocytes and Stellate Cells

Y. Shimizu, K. Shimotohno, H. Nishitsuji, 2013, Journal of Virology.

Oligoribonucleotides containing 8-oxo-7,8-dihydroguanosine and 8-oxo-7,8-dihydro-2'-O-methylguanosine: synthesis and base pairing properties.

S. Yokoyama, H. Takaku, B. Moon, 1998, Bioorganic & medicinal chemistry letters.

Murine Splenic Natural Killer Cells Do Not Develop Immunological Memory after Re-Encounter with Mycobacterium bovis BCG

H. Takaku, Mamoru Kawahara, N. Hasegawa, 2016, PloS one.

Intradermal immunization with combined baculovirus and tumor cell lysate induces effective antitumor immunity in mice.

H. Takaku, Mamoru Kawahara, M. Kawahara, 2013, International journal of oncology.

Antisense therapy of influenza.

T. Abe, N. Miyano-Kurosaki, H. Takaku, 2001, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Short-hairpin RNAs synthesized by T7 phage polymerase do not induce interferon

N. Miyano-Kurosaki, H. Takaku, K. Yamaguchi, 2007, Nucleic acids research.

Lack of Interferon (IFN) Response to T7 Transcribed pppG (n)(n = 2,3)-shRNA

N. Miyano-Kurosaki, H. Takaku, K. Hashimoto, 2007, Nucleosides, nucleotides & nucleic acids.

Combination Therapy for Hepatitis C Virus with Heat-Shock Protein 90 Inhibitor 17-AAG and Proteasome Inhibitor MG132

K. Shimotohno, H. Takaku, Saori Yamaguchi, 2010, Antiviral chemistry & chemotherapy.

Heat-shock Protein 90 Is Essential for Stabilization of the Hepatitis C Virus Nonstructural Protein NS3*

K. Shimotohno, H. Takaku, Saori Yamaguchi, 2009, Journal of Biological Chemistry.

2-aminophenoxazine-3-one suppresses the growth of mouse malignant melanoma B16 cells transplanted into C57BL/6Cr Slc mice.

K. Shirato, A. Tomoda, N. Miyano-Kurosaki, 2006, Biological & pharmaceutical bulletin.

A tumor lysate is an effective vaccine antigen for the stimulation of CD4+ T-cell function and subsequent induction of antitumor immunity mediated by CD8+ T cells

H. Takaku, Mamoru Kawahara, M. Kawahara, 2015, Cancer biology & therapy.

Hepatitis C virus utilizes VLDLR as a novel entry pathway

K. Shimotohno, H. Nishitsuji, H. Takaku, 2015, Proceedings of the National Academy of Sciences.

Misreading of RNA Templates Containing 8-Oxo-7,8-Dihydroguanosine Or 8-Oxo-2′-O-Methylguanosine in cDNA Synthesis by Reverse Transcriptases

S. Yokoyama, Ji Young Kim, H. Takaku, 1999 .

PKC412 (CGP41251) modulates the proliferation and lipopolysaccharide-induced inflammatory responses of RAW 264.7 macrophages.

M. Itakura, H. Takaku, H. Inoue, 2007, Biochemical and biophysical research communications.

Anti-HIV-1 Activity by a Triple-Helix Forming Oligonucleotides Targeted to Polypurine Tract on Viral RNA

T. Saito, N. Miyano-Kurosaki, H. Takaku, 2000, Nucleosides, nucleotides & nucleic acids.

Inhibition of HIV‐1 replication by a two‐strand system (FTFOs) targeted to the polypurine tract

N. Miyano-Kurosaki, H. Takaku, N. Yamamoto, 1999, FEBS letters.

Inhibition of HIV-1 replication by triple-helix-forming phosphorothioate oligonucleotides targeted to the polypurine tract.

Y. Koyanagi, H. Takaku, N. Yamamoto, 1997, Biochemical and biophysical research communications.

Sequence‐specific inhibition of a transcription factor by circular dumbbell DNA oligonucleotides

N. Miyano-Kurosaki, H. Takaku, H. Takeuchi, 1999, FEBS letters.

Evaluating target silencing by short hairpin RNA mediated by the group I intron in cultured mammalian cells

H. Takaku, Kousei Noguchi, Yoshio Ishitu, 2011, BMC biotechnology.

Effects of anticodon 2'-O-methylations on tRNA codon recognition in an Escherichia coli cell-free translation.

S. Yokoyama, H. Takaku, K. Takai, 2000, RNA.

Suppression of hepatitis C virus replication by baculovirus vector‐mediated short‐hairpin RNA expression

H. Takaku, M. O. Chang, Hitoshi Suzuki, 2008, FEBS letters.

Suppression of HIV-1 Replication by a Combination of Endonucleolytic Ribozymes (RNase P and tRNase ZL)

N. Miyano-Kurosaki, H. Takaku, Y. Habu, 2006, Nucleosides, nucleotides & nucleic acids.

EFFECTIVE SUPPRESSION OF HIV-1 GENE EXPRESSION BY A MAMMALIAN tRNA 3′ PROCESSING ENDORIBONUCLEASE AND EXTERNAL GUIDE SEQUENCE OLIGOZYMES

N. Miyano-Kurosaki, H. Takaku, H. Takeuchi, 2001, Nucleosides, nucleotides & nucleic acids.

Influenza Virus-like Particles Containing HA, NA, and M1 Induced Protection in Chickens against a Lethal Challenge with the HighlyPathogenic H5N1 Avian Influenza Virus

H. Takaku, Y. Sakoda, H. Kida, 2013 .

The Middle to 3′ End of the Hiv-1 Vif Gene Sequence is Important for Vif Biological Activity and Could be Used for Antisense Oligonucleotide Targets

A. Sakamoto, N. Miyano-Kurosaki, H. Takaku, 2005, Nucleosides, nucleotides & nucleic acids.

Intracellular expression of antisense RNA transcripts complementary to the human immunodeficiency virus type-1 vif gene inhibits viral replication in infected T-lymphoblastoid cells.

A. Sakamoto, N. Miyano-Kurosaki, H. Takaku, 2004, Biochemical and biophysical research communications.

Inhibitory effects of an antisense oligonucleotide in an experimentally infected mouse model of influenza A virus.

T. Abe, N. Miyano-Kurosaki, H. Takaku, 2000, Biochemical and biophysical research communications.

Resistance to influenza A virus infection by antigen-conjugated CpG oligonucleotides, a novel antigen-specific immunomodulator.

M. Fujii, N. Miyano-Kurosaki, H. Takaku, 2005, Biochemical and biophysical research communications.

Antitumor effects of baculovirus-infected dendritic cells against human pancreatic carcinoma

M. Kitajima, H. Takaku, T. Suzuki, 2014, Gene Therapy.

Inhibition of human immunodeficiency virus 1 replication in vitro by a self-stabilized oligonucleotide with 2'-O-methyl-guanosine-uridine quadruplex motifs.

H. Takaku, H. Takeuchi, T. Kuwasaki, 2003, The Journal of antimicrobial chemotherapy.

Inhibition of Human Immunodeficiency Virus Type 1 Activity In Vitro by a New Self-Stabilized Oligonucleotide with Guanosine-Thymidine Quadruplex Motifs

G. Kawai, N. Miyano-Kurosaki, H. Takaku, 2002, Journal of Virology.

Methoxyethoxymethyl group for the protection of uracil residue in oligoribonucleotide synthesis

H. Takaku, S. Ueda, T. Ito, 1984 .

In vitro and in vivo anti-influenza A virus activity of antisense oligonucleotides.

T. Abe, H. Takaku, T. Yokota, 1999, Nucleosides & nucleotides.

Influenza Virus Infection in Mice Response and Confers Protection from Lethal Baculovirus Induces an Innate Immune

Y. Matsuura, T. Abe, H. Hamazaki, 2013 .

2 Inhibition of hepatitis C virus RNA replication by short hairpin

K. Shimotohno, H. Hamazaki, N. Miyano-Kurosaki, 2006 .

Inhibition of the human chemokine receptor CXCR4 by antisense phosphorothioate oligodeoxyribonucleotides

N. Miyano-Kurosaki, H. Takaku, T. Saitou, 2001, FEBS letters.

Antisense Phosphorothioate Oligonucleotides Targeted to the Human Chemokine Receptor CXCR4

N. Miyano-Kurosaki, H. Takaku, T. Kimura, 2000, Nucleosides, nucleotides & nucleic acids.

Phosphorothioate analogues of oligodeoxyribonucleotide: synthesis and activity as inhibitors of replication of human immunodeficiency virus.

S. Kim, H. Takaku, N. Yamamoto, 1991, Biochemical and biophysical research communications.

Antiviral effect of phosphorothioate oligodeoxyribonucleotides complementary to human immunodeficiency virus

Y. Shoji, H. Takaku, H. Nakashima, 1995, Bioorganic & Medicinal Chemistry.

Use of new phosphonylating and coupling agents in the synthesis of oligodeoxyribonucleotides via the H-phosphonate approach.

H. Yamane, H. Takaku, N. Yamamoto, 1990, Nucleic acids research.

Properties and Anti-HIV Activity of Nicked Dumbbell Oligonucleotides

H. Takaku, H. Nakashima, N. Yamamoto, 1996 .

Antisense oligonucleotides directed against the viral RNA polymerase gene enhance survival of mice infected with influenza A

T. Abe, N. Miyano-Kurosaki, H. Takaku, 1999, Nature Biotechnology.

The RNA-editing Enzyme APOBEC1 Requires Heterogeneous Nuclear Ribonucleoprotein Q Isoform 6 for Efficient Interaction with Interleukin-8 mRNA*

Y. Shimizu, K. Shimotohno, H. Marusawa, 2014, The Journal of Biological Chemistry.

Specific inhibition of influenza virus RNA polymerase and nucleoprotein genes expression by liposomally endocapsulated antisense phosphorothioate oligonucleotides: penetration and localization of oligonucleotides in clone 76 cells.

H. Takaku, T. Yokota, K. Takai, 1997, Biochemical and biophysical research communications.

Effects of Tributyltin and Diazinon on the Intertidal Marine Harpacticoid Copepod Tigriopus japonicus

Xuchun Qiu, H. Takaku, I. Kang, 2020, Journal of the Faculty of Agriculture, Kyushu University.

Inhibition of HIV-1 Replication by an HIV-1 Dependent Ribozyme Expression Vector with the Cre/loxP (ON/OFF) System

N. Miyano-Kurosaki, H. Takaku, H. Takeuchi, 2002, Antiviral chemistry & chemotherapy.

Synthesis and Properties of Non-Hammerhead RNA Using 1-(2-Chloroethoxy)-ethyl Group for the Protection of 2′-Hydroxyl Function

H. Takaku, O. Sakatsume, Takashi Ogawa, 1991 .

1-(2-Chloroethoxy)ethyl group for the protection of 2'-hydroxyl group in the synthesis of oligoribonucleotides

H. Takaku, O. Sakatsume, S. Yamakage, 1989 .

8-QUINOLYL NUCLEOSIDE 5′-PHOSPHATES AS A USEFUL INTERMEDIATE FOR THE SYNTHESIS OF NUCLEOSIDE 5′-DI- AND 5′-TRI-PHOSPHATES

H. Takaku, T. Hata, T. Konishi, 1977 .

A Study on Phosphorylation by Means of 8-Quinolyl Phosphates

H. Takaku, Y. Shimada, K. Arai, 1974 .

Inhibition of HIV-1 replication by vesicular stomatitis virus envelope glycoprotein pseudotyped baculovirus vector-transduced ribozyme in mammalian cells.

N. Miyano-Kurosaki, H. Takaku, Hitoshi Suzuki, 2006, Biochemical and biophysical research communications.

Suppression of Human Immunodeficiency Virus Type 1 (HIV-1) Replication by an HIV-1-dependent Double Locked Vector with the Cre/loxP System

N. Miyano-Kurosaki, H. Takaku, H. Takeuchi, 2005, Nucleosides, nucleotides & nucleic acids.

Solid phase synthesis of oligoribonucleotides using the 1-[(2-chloro-4-methyl)phenyl]-4-methoxypiperidin-4-yl (Ctmp) group for the protection of the 2'-hydroxy functions and the H-phosphonate approach.

H. Takaku, C. Reese, O. Sakatsume, 1989, Nucleic acids research.

Inhibition of human telomerase activity by antisense phosphorothioate oligonucleotides encapsulated with the transfection reagent, FuGENE6, in HeLa cells.

N. Miyano-Kurosaki, H. Takaku, K. Takai, 2000, Antisense & nucleic acid drug development.

Specific inhibition of human telomerase activity by transfection reagent, FuGENE6‐antisense phosphorothioate oligonucleotide complex in HeLa cells

N. Miyano-Kurosaki, H. Takaku, K. Takai, 1999, FEBS letters.

Properties of nicked and circular dumbbell RNA/DNA chimeric oligonucleotides containing antisense phosphodiester oligodeoxynucleotides.

T. Saito, T. Abe, H. Takaku, 1998, Bioorganic & medicinal chemistry.

Specific Inhibition of Influenza Virus RNA Polymerase and Nucleoprotein Gene Expression by Liposomally Encapsulated Antisense Phosphorothioate Oligonucleotides in MDCK Cells

T. Abe, H. Takaku, T. Yokota, 1998, Antiviral chemistry & chemotherapy.

Specific inhibition of influenza virus RNA polymerase and nucleoprotein gene expression by circular dumbbell RNA/DNA chimeric oligonucleotides containing antisense phosphodiester oligonucleotides

T. Abe, H. Takaku, T. Yokota, 1998, FEBS letters.

Synthesis of 8-Substituted Analogues of 2′-Deoxy-2′-Fluoroadenosine

H. Takaku, T. Maruyama, S. Kozai, 1999 .

Large scale synthesis of the cap part in messenger RNA using a new type of bifunctional phosphorylating reagent

H. Takaku, T. Hata, M. Ishikawa, 1994 .

Interactions of a didomain fragment of the Drosophila Sex-lethal protein with single-stranded uridine-rich oligoribonucleotides derived from the transformer and Sex-lethal messenger RNA precursors: NMR with residue-selective [5-2H]uridine substitutions

S. Yokoyama, Y. Muto, Satoru Watanabe, 2000, Journal of biomolecular NMR.

Human immunodeficiency virus‐1 Nef suppresses Hsp70‐mediated Tat activation

H. Nishitsuji, H. Takaku, Ryuichi Sugiyama, 2011, FEBS letters.

ATP1B3 Protein Modulates the Restriction of HIV-1 Production and Nuclear Factor κ Light Chain Enhancer of Activated B Cells (NF-κB) Activation by BST-2*

H. Nishitsuji, H. Takaku, M. Abe, 2015, The Journal of Biological Chemistry.

Synthesis of 2'- or 3'-o-(4-methoxybenzyl)nucleosides and its application in the 3'-terminal nonanucleotide sequence of rous sarcoma virus 35S RNA synthesis

H. Takaku, Hiromichi Tsuchiya, K. Kamaike, 1986 .

A Convenient Method for the Synthesis of Adenylyl-(2′–5′)-adenylyl(2′–5′)-adenosine Using 3′-O-Benzoyladenosine Derivatives

H. Takaku, S. Ueda, 1983 .

Genetic Analysis of Hepatitis C Virus with Defective Genome and Its Infectivity in Vitro

Y. Shimizu, K. Shimotohno, M. Hijikata, 2009, Journal of Virology.

Properties and Anti-Hiv Activity of Hairpin Antisense Oligonucleotides Containing 2′-Methoxynucleosides with Base-Pairing in the Stem Region at the 3′-End

H. Takaku, N. Yamamoto, H. Nakashima, 1996 .

Properties of base-pairing in the stem region of hairpin antisense oligonucleotides containing 2'-methoxynucleosides.

H. Takaku, K. Takai, S. Tsukahara, 1995, Biochimica et biophysica acta.

Mechanisms of the inhibition of reverse transcription by unmodified and modified antisense oligonucleotides

S. Yokoyama, K. Sakamoto, H. Takaku, 1993, FEBS letters.

In Vitro and in Vivo Transport and Delivery of Phosphorothioate Oligonucleotides with Cationic Liposomes

N. Miyano-Kurosaki, H. Takaku, H. Takeuchi, 2004, Antiviral chemistry & chemotherapy.

Induction of heat-shock protein 70 by prostaglandin A₁ inhibits HIV-1 Vif-mediated degradation of APOBEC3G.

Y. Murakami, H. Nishitsuji, H. Takaku, 2013, Antiviral research.

Selective deuteration of RNA for NMR signal assignment.

S. Yokoyama, Y. Muto, K. Watanabe, 1995, Nucleic acids symposium series.

Oligonucleotide synthesis. Part 18. Synthesis of bis(5-chloro-8-quinolyl) nucleoside 5'-phosphates in oligoribonucleotide synthesis by the phosphotriester approach

H. Takaku, K. Kamaike, K. Kasuga, 1982 .

Use of the (butylthio)carbonyl group to protect uracil and guanine residues in oligoribonucleotide synthesis.

H. Takaku, M. Fujii, Y. Horinouchi, 1987 .

USE OF 3,4-DIMETHOXYBENZYL GROUP AS A PROTECTING GROUP FOR THE 2′-HYDROXYL GROUP IN THE SYNTHESIS OF OLIGORIBONUCLEOTIDES

H. Takaku, T. Ito, K. Imai, 1986 .

3,4-DIMETHOXYBENZYL GROUP : A NEW PROTECTING GROUP FOR THE GUANOSINE RESIDUE DURING OLIGONUCLEOTIDE SYNTHESIS

H. Takaku, S. Ueda, Y. Tomita, 1984 .

5'-linked lipid-oligodeoxyridonucleotide derivatives as inhibitors of human immunodeficiency virus replication.

S. Kim, H. Takaku, N. Yamamoto, 1996, Bioorganic & medicinal chemistry.

Cleavage effect of oligoribonucleotides substituted at the cleavage sites with modified pyrimidine- and purine-nucleosides.

S. Yokoyama, K. Sakamoto, H. Takaku, 1997, Biochimica et biophysica acta.

The Relationship between Conformation and Biological Activity of 8-substituted Analogues of 2′,5′-Oligoadenylates

H. Takaku, K. Kanbara, N. Yamamoto, 1994 .

Characterization and biological activity of 8-substituted analogues of 2',5'-oligoadenylates.

H. Takaku, H. Nakashima, K. Kanbara, 1993, Biochimica et biophysica acta.

Purine 8-substitution modulates the ribonuclease L binding and activation abilities of 2',5'-oligoadenylates.

S. Yokoyama, H. Takaku, R. Sobol, 1991, Biochemical and biophysical research communications.

Antisense oligodeoxynucleotide complementary to CXCR4 mRNA block replication of HIV-1 in COS cells.

H. Takaku, T. Kimura, N. Yamamoto, 1999, Nucleosides & nucleotides.

HIV gene therapy using RNA virus systems.

N. Miyano-Kurosaki, H. Takaku, M. Hayafune, 2006, Nucleic acids symposium series.

Anti-HIV-1 activity of an antisense phosphorothioate oligonucleotide bearing imidazole and primary amine groups.

N. Miyano-Kurosaki, H. Takaku, M. Shirakawa, 2001, Bioorganic & medicinal chemistry.

SYNTHESIS OF OLIGORIBONUCLEOTIDES USING 4-METHOXYBENZYL GROUP AS A NEW PROTECTING GROUP OF THE 2′-HYDROXYL GROUP OF ADENOSINE

H. Takaku, K. Kamaike, 1982 .

A single uridine modification at the wobble position of an artificial tRNA enhances wobbling in an Escherichia coli cell‐free translation system

S. Yokoyama, H. Takaku, K. Takai, 1999, FEBS letters.

NMR analysis of the hydrogen bonding interactions of the RNA-binding domains of the Drosophila sex-lethal protein with target RNA fragments with site-specific [3-15N]uridine substitutions.

S. Yokoyama, Y. Muto, Y. Shimura, 1997, Nucleic acids research.

SIMPLE SYNTHESIS OF 9-(5-DEOXY-β-D-ERYTHRO-PENT-4-ENOFURANOSYL)ADENINE FROM ADENOSINE BY SELENOXIDE FRAGMENTATION

H. Takaku, K. Kimura, T. Nomoto, 1981 .

Characterization of the secondary structure of an oligonucleotide corresponding to the autocleavage site of a precursor RNA from bacteriophage T4.

S. Yokoyama, K. Sakamoto, H. Takaku, 1994, Biochimica et biophysica acta.

Oligonucleotide synthesis. 10. (8-Quinolinesulfonyl)tetrazole: a new type of highly efficient coupling agent for the synthesis of ribooligonucleotides by the phosphotriester approach

H. Takaku, Masatoshi Yoshida, 1981 .

A convenient method for insertion of the 5'-terminal phosphate group in the triester approach to oligoribonucleotide synthesis

H. Takaku, Masatoshi Yoshida, R. Yamaguchi, 1980 .

8-Quinolinesulfonyl chloride as a coupling agent in oligonucleotide synthesis via phosphotriester approach

H. Takaku, Masatoshi Yoshida, T. Hata, 1978 .

Synthesis of ribo oligo nucleotides using the 4 methoxybenzyl group as a new protecting group for the 2' hydroxyl group/

H. Takaku, Hiromichi Tsuchiya, K. Kamaike, 1984 .

OLIGONUCLEOTIDE SYNTHESIS. PART 21. SYNTHESIS OF RIBOOLIGONUCLEOTIDES USING THE 4-METHOXYBENZYL GROUP AS A NEW PROTECTING GROUP FOR THE 2′-HYDROXYL GROUP

H. Takaku, Hiromichi Tsuchiya, K. Kamaike, 1984 .

Synthesis of Oligoribonucleotides Bearing Morpholino-Nucleosides with Carbamate Internucleoside Linkages at the 3′-Terminus

H. Takaku, O. Sakatsume, Hiroaki Tanaka, 1993 .

Properties of triple helix formation with oligodeoxyribonucleotides containing 8-oxo-2'-deoxyadenosine and 2'-modified nucleoside derivatives.

T. Maruyama, H. Takaku, K. Takai, 1996, Bioorganic & medicinal chemistry.

pH‐independent inhibition of restriction endonuclease cleavage via triple helix formation by oligonucleotides containing 8‐oxo‐2′‐deoxyadenosine

H. Takaku, K. Takai, H. Yamakawa, 1994, FEBS letters.

Solid-Phase Synthesis of Oligoribonucleotides Using 5′-9-Fluorenylmethoxycarbonyl and 2′-1-(Isopropoxyl)ethyl Protection

H. Takaku, Takashi Ogawa, H. Hosaka, 1991 .

Knocking out a specific tRNA species within unfractionated Escherichia coli tRNA by using antisense (complementary) oligodeoxyribonucleotides

S. Yokoyama, H. Takaku, K. Takai, 1998, FEBS letters.

A New Phosphorylating Agent, Di(2,2,2-Trifluoroethyl) Trimethylsilyl Phosphite. Its Application in Dna Synthesis by The Phosphotriester Approach

H. Takaku, T. Ito, K. Imai, 1985 .

Di(2,2,2-trifluoroethyl) phosphonate, a new phosphorylating agent, its application in the synthesis of oligodeoxyribonucleotides by the phosphotriester approach

H. Takaku, Hiromichi Tsuchiya, K. Imai, 1984 .

The influence of oligodeoxyribonucleotide phosphorothioate pyrimidine strands on triplex formation

S. Yokoyama, H. Takaku, S. Tsukahara, 1992, FEBS letters.

Nucleoside phosphite, O-bis(1,1,1,3,3,3-hexafluoro-2-propyl) deoxyribonucleosid-3'-yl phosphites. A versatile synthetic intermediate for phosphonate modified nucleotide and oligonucleotide synthesis

H. Takaku, Hiroyuki Nakamura, H. Hosaka, 1992 .

Synthesis of Oligodeoxyribonucleotide Analogues by Use of Deoxyribonucleoside-3′-yl O-bis(1,1,1,3,3,3-Hexafluoro-2-Propyl) Phosphites as New Key Intermediates

H. Takaku, H. Nakashima, N. Yamamoto, 1992 .

A convenient approach to the synthesis of medium size deoxyribooligonucleotides by improved new phosphite method

H. Takaku, Yoshikazu Suzuki, H. Hosaka, 1991 .

Synthesis of antisense oligodeoxyribonucleotide analogues by use of deoxyribonucleoside 3′‐bis(1, 1, 1, 3,3,3‐hexafluoro‐2‐propyl) phosphites as new key intermediates

H. Takaku, Yoshikazu Suzuki, H. Hosaka, 1991 .

Anti-HIV activities and physicochemical properties of phosphorothioate analogues complementary to HIV sequences

H. Takaku, H. Nakashima, K. Kanbara, 1993 .

Solid‐Phase Synthesis of Oligoribonucleotides Using 5′‐9‐ Fluorenylmethoxycarbonyl and 2′‐1‐(Isopropoxyl)ethyl Protection.

H. Takaku, Takashi Ogawa, H. Hosaka, 1992 .

Chemical synthesis and biological activities of analogues of 2',5'-oligoadenylates containing 8-substituted adenosine derivatives.

S. Yokoyama, G. Kawai, H. Takaku, 1990, Nucleic acids research.

Sense codon-dependent introduction of unnatural amino acids into multiple sites of a protein.

M. Sisido, H. Takaku, T. Hohsaka, 2000, Biochemical and Biophysical Research Communications - BBRC.

Specific inactivation of Escherichia coli tRNA(Phe) by antisense DNA-treatment under Mg2+-deficient conditions.

S. Yokoyama, H. Takaku, K. Takai, 2000, Bioorganic & medicinal chemistry.

In VitroCodon-Reading Specificities of Unmodified tRNA Molecules with Different Anticodons on the Sequence Background ofEscherichia colitRNASer1☆

S. Yokoyama, H. Takaku, K. Takai, 1999 .

Codon-reading specificity of an unmodified form of Escherichia coli tRNA1Ser in cell-free protein synthesis.

S. Yokoyama, H. Takaku, K. Takai, 1996, Nucleic acids research.

A Convenient Approach to the Synthesis of Azido-Acyclic Nucleosides

H. Takaku, N. Yamamoto, Takashi Ogawa, 1989 .

A NOVEL β0-THALASSEMIA MUTATION AT CODON 55 (−A) AND A RARE 17 bp DELETION AT CODONS 126–131 IN THE INDIAN POPULATION

H. Takaku, D. Mohanty, R. Kiyama, 2002, Hemoglobin.

5-CHLORO-8-QUINOLYL GROUP AS A PROTECTING GROUP ON PHOSPHOMONOESTERS IN THE SYNTHESIS OF OLIGONUCLEOTIDES

H. Takaku, T. Hata, R. Yamaguchi, 1979 .

Purine 8-substitution modulates the recognition by restriction endodeoxyribonuclease EcoRI of octadeoxyribonucleotides (dGGAATTCC)

H. Takaku, T. Ichikawa, H. Komatsu, 1992 .

Phosphorylation of alcohols with diethyl phosphorochloridodithioite

H. Takaku, Y. Shimada, 1972 .

Synthesis and Biological Evaluation of some Acyclic Nucleoside Cyclic Phosphoramidate Derivatives

E. Clercq, H. Takaku, S. Yoshida, 1987 .

A combined use of triphenyl phosphite and 2,2'-dipyridyl diselenide as a coupling reagent in oligonucleotide synthesis.

H. Takaku, Y. Nakajima, T. Hata, 1976, Nucleic acids research.

BIS(2,2,2-TRIFLUOROETHYL) PHOSPHONATE, A NEW PHOSPHORYLATING AGENT, ITS APPLICATION IN THE SYNTHESIS OF OLIGODEOXYRIBONUCLEOTIDES BY THE PHOSPHOTRIESTER APPROACH

H. Takaku, Hiromichi Tsuchiya, K. Imai, 1985 .

Selective removal of terminal dimethoxytrityl groups

H. Takaku, K. Morita, Takashi Sumiuchi, 1983 .

A SIMPLE SYNTHETIC METHOD OF DEOXYRIBODINUCLEOTIDE BLOCKS

H. Takaku, K. Kamaike, M. Suetake, 1983 .

8-QUINOLINESULFONYL CHLORIDE: A NEW COUPLING AGENT IN OLIGORIBONUCLEOTIDE SYNTHESIS VIA PHOSPHOTRIESTER APPROACH

H. Takaku, Masatoshi Yoshida, T. Hata, 1979 .

A Convenient Approach to the Synthesis of Deoxyribonucleoside-3′-hydrogen Phosphonates via Bis(1,1,1,3,3,3-hexafluoro-2-propyl) Phosphonate Intermediate

H. Takaku, O. Sakatsume, S. Yamakage, 1988 .

8-HYDROXYQUINOLINE AS A REAGENT FOR PROTECTION OF PHOSPHATES IN OLIGONUCLEOTIDE SYNTHESIS

H. Takaku, T. Hata, Y. Shimada, 1975 .

A convenient approach to the synthesis of medium size oligodeoxyribonucleotides by improved new phosphite method.

H. Takaku, H. Sato, Y. Suzuki, 1991, Nucleic acids research.

Nonenzymatic sequence-specific cleavage of duplex DNA via triple-helix formation by homopyrimidine phosphorothioate oligonucleotides.

H. Takaku, K. Takai, S. Tsukahara, 1996, Bioorganic & medicinal chemistry.

Solid phase synthesis of oligoribonucleotides by the phosphoramidite approach using 2'-O-1-(2-chloroethoxy)ethyl protection

K. Miura, H. Takaku, I. Hirao, 1991 .

Inhibition of Restriction Enzyme Ksp 632-I Via Triple Helix Formation by Phosphorothioate Oligonucleotides

H. Takaku, K. Takai, S. Tsukahara, 1994 .

Nucleoside Phosphite, O-Bis(1,1,1,3,3,3-hexafluoro-2-propyl) Deoxyribonucleosid-3′-yl Phosphites. A Versatile Synthetic Intermediate for Phosphonate Modified Nucleotide and Oligonucleotide Synthesis.

H. Takaku, Hiroyuki Nakamura, H. Hosaka, 2010 .

New phosphite method: the synthesis of oligodeoxyribonucleotides by use of deoxyribonucleoside 3'-[bis(1,1,1,3,3,3-hexafluoro-2-propyl) phosphites] as new key intermediates

Hirotaka Sato, H. Takaku, Tetsuo Watanabe, 1989 .

Use of the 2-(4-Pyridyl) ethyl protecting group in the synthesis of DNA Fragments via phosphoramidite intermediates

H. Takaku, M. Kawashima, M. Takaki, 1989 .

Synthesis of Antisense Oligodeoxyribonucleotide Analogues by Use of Deoxyribonucleoside 3′-Bis(1,1,1,3,3,3-hexafluoro-2-propyl) Phosphites as New Key Intermediates.

H. Takaku, Yoshikazu Suzuki, H. Hosaka, 2010 .

Synthesis of Protected 8-Substituted Deoxyribonucleosides and Its Helix Stability in Oligodeoxyribonucleotides Containing the Eco RI Recognition Site

H. Takaku, T. Ichikawa, H. Komatsu, 1992 .

Self-cleavage of p2Sp1 RNA with Mg2+ and non-ionic detergent (Brij 58).

G. Kawai, H. Takaku, K. Takai, 2000, Journal of inorganic biochemistry.

The stem hairpin loop structure of p2Sp1 RNA is required for RNA-cleaving activity.

G. Kawai, H. Takaku, K. Takai, 1999, Biochimica et biophysica acta.

Cleavage reaction of a synthetic oligoribonucleotide corresponding to the autocleavage site of a precursor RNA from bacteriophage T4

K. Sakamoto, H. Takaku, S. Yokoyama, 1991, FEBS letters.

Properties and Anti-HIV Activity of Circular Sense and Antisense Oligonucleotides

H. Takaku, H. Nakashima, N. Yamamoto, 1995 .

A new modified DNA enzyme that targets influenza virus A mRNA inhibits viral infection in cultured cells

T. Abe, H. Hamazaki, N. Miyano-Kurosaki, 2004, FEBS letters.

Synthesis and Properties of 2', 5'-Adenylate Trimers Bearing 2'-Terminal 8-Bromo- or 8-Hydroxyadenosine

H. Takaku, S. Yoshida, 1986 .

New Approach to the Synthesis of Deoxyribonucleoside Phosphoramidite Derivatives

H. Takaku, S. Hamamoto, 1986 .

An easy cell-free protein synthesis system dependent on the addition of crude Escherichia coli tRNA.

S. Yokoyama, H. Takaku, K. Takai, 2000, Journal of biochemistry.

Inhibition of HIV-1 replication by a new type of circular dumbbell RNA/DNA chimeric oligonucleotides.

T. Abe, N. Miyano-Kurosaki, H. Takaku, 2000, Biochemical and biophysical research communications.

Silencing of HIV-1 Gene Expression by Two Types of siRNA Expression Systems

N. Miyano-Kurosaki, H. Takaku, M. Hayafune, 2006, Antiviral chemistry & chemotherapy.

4-CHLOROPHENYL 5-CHLORO-8-QUINOLYL PHOSPHOROCHLORIDATE: A PRACTICALLY USEFUL PHOSPHORYLATING AGENT FOR OLIGORIBONUCLEOTIDE SYNTHESIS VIA PHOSPHOTRIESTER APPROACH

H. Takaku, Masatoshi Yoshida, K. Kamaike, 1981 .

1,1,1,3,3,3-Hexafluoro-2-propyl group as a new phosphate protecting group for oligoribonucleotide synthesis in the phosphotriester approach

H. Takaku, M. Fujii, Masaru Uemura, 1989 .

Inhibition of HIV-1 replication by RNA with a microRNA-like function.

H. Takaku, Keijiro Kato, Takashi Senoki, 2013, International journal of molecular medicine.

Interaction of human T‐cell lymphotropic virus type I Rex protein with Dicer suppresses RNAi silencing

H. Nishitsuji, H. Takaku, M. Abe, 2010, FEBS letters.

Gene silencing of virus replication by RNA interference.

N. Miyano-Kurosaki, H. Takaku, N. Miyano-kurosaki, 2006, Handbook of experimental pharmacology.

Gene Silencing of HIV-1 by RNA Interference

H. Takaku, 2004, Antiviral chemistry & chemotherapy.

Specific HIV-1 env gene silencing by small interfering RNAs in human peripheral blood mononuclear cells

N. Miyano-Kurosaki, H. Takaku, M. Hayafune, 2003, Gene Therapy.

Prevention of HIV-1 infection in human peripheral blood mononuclear cells by specific RNA interference.

N. Miyano-Kurosaki, H. Takaku, M. Hayafune, 2002, Nucleic acids research.

HIV-1 Suppressive Sequences Are Modulated by Rev Transport of Unspliced RNA and Are Required for Efficient HIV-1 Production

N. Yamamoto, H. Takaku, T. Hirano, 2012, PloS one.

Structure, interaction and real‐time monitoring of the enzymatic reaction of wild‐type APOBEC3G

S. Yokoyama, N. Kobayashi, H. Takaku, 2009, The EMBO journal.

Inhibition of HCV Replication in HCV Replicon by shRNAs

K. Shimotohno, H. Hamazaki, N. Miyano-Kurosaki, 2006, Nucleosides, nucleotides & nucleic acids.

HIV-1 RT-dependent DNAzyme expression inhibits HIV-1 replication without the emergence of escape viruses

Ryuichi Sugiyama, Hiroshi Takaku, Masaaki Hayafune, 2010, Nucleic Acids Res..

ZNF10 inhibits HIV‐1 LTR activity through interaction with NF‐κB and Sp1 binding motifs

H. Nishitsuji, H. Takaku, Ryuichi Sugiyama, 2015, FEBS letters.

ZBRK1 represses HIV‐1 LTR‐mediated transcription

H. Nishitsuji, H. Takaku, M. Abe, 2012, FEBS letters.

Inhibition of HIV-1 replication by long-term treatment with a chimeric RNA containing shRNA and TAR decoy RNA.

N. Yamamoto, N. Miyano-Kurosaki, H. Takaku, 2009, Antiviral research.

Cyclosporin A inhibits the propagation of influenza virus by interfering with a late event in the virus life cycle.

M. Tashiro, N. Yamamoto, H. Takaku, 2013, Japanese journal of infectious diseases.

High Yield Production of Influenza Virus in Madin Darby Canine Kidney (MDCK) Cells with Stable Knockdown of IRF7

M. Tashiro, N. Yamamoto, H. Takaku, 2013, PloS one.

HIV-1 Gag-Virus-Like Particles Inhibit HIV-1 Replication in Dendritic Cells and T Cells through IFN-α-Dependent Upregulation of APOBEC3G and 3F

Tomoyuki Suzuki, N. Yamamoto, H. Takaku, 2012, Journal of Innate Immunity.

Impact of age at marriage and migration on HIV and AIDS epidemics in Japan

Nazrul Islam Mondal, Y. Ohkusa, H. Takaku, 2009, International journal for equity in health.

HIV/AIDS acquisition and transmission in Bangladesh: turning to the concentrated epidemic.

Nazrul Islam Mondal, Y. Ohkusa, T. Sugawara, 2009, Japanese journal of infectious diseases.

Recombinant baculovirus expressing the FrC-OVA protein induces protective antitumor immunity in an EG7-OVA mouse model

Tomoyuki Suzuki, H. Takaku, M. O. Chang, 2019, Journal of Biological Engineering.

Heat Shock Protein 70 Inhibits HIV-1 Vif-mediated Ubiquitination and Degradation of APOBEC3G*

A. Ryo, H. Nishitsuji, H. Takaku, 2011, The Journal of Biological Chemistry.

Baculovirus-mediated bispecific short-hairpin small-interfering RNAs have remarkable ability to cope with both influenza viruses A and B.

Tomoyuki Suzuki, H. Takaku, Hitoshi Suzuki, 2009, Oligonucleotides.

Two Basic Regions of NCp7 Are Sufficient for Conformational Conversion of HIV-1 Dimerization Initiation Site from Kissing-loop Dimer to Extended-duplex Dimer*

G. Kawai, Y. Koyanagi, H. Takaku, 2001, The Journal of Biological Chemistry.

Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers.

Gota Kawai, Hiroshi Takaku, Yoshio Koyanagi, 2005, Journal of biochemistry.

NMR analysis of intra- and inter-molecular stems in the dimerization initiation site of the HIV-1 genome.

Y. Hayashi, G. Kawai, Y. Koyanagi, 2000, Journal of biochemistry.

Structural requirement for the two-step dimerization of human immunodeficiency virus type 1 genome.

G. Kawai, Y. Koyanagi, H. Takaku, 2000, RNA.

Prominent Steatosis with Hypermetabolism of the Cell Line Permissive for Years of Infection with Hepatitis C Virus

T. Hibi, H. Saito, H. Ebinuma, 2014, PloS one.

Infectivity of Hepatitis C Virus Is Influenced by Association with Apolipoprotein E Isoforms

Y. Shimizu, K. Shimotohno, T. Wakita, 2010, Journal of Virology.

Baculovirus-mediated interferon alleviates dimethylnitrosamine-induced liver cirrhosis symptoms in a murine model

Y. Matsuura, H. Takaku, Hitoshi Suzuki, 2008, Gene Therapy.

Interaction analysis between tmRNA and SmpB from Thermus thermophilus.

Gota Kawai, Akira Muto, Shigeyuki Yokoyama, 2005, Journal of biochemistry.

Inhibition of HIV-1 gene expression by retroviral vector-mediated small-guide RNAs that direct specific RNA cleavage by tRNase ZL

N. Miyano-Kurosaki, H. Takaku, M. Nashimoto, 2005, Nucleic acids research.

Inhibitory Effect of Modified 5′-Capped Short RNA Fragments on Influenza Virus RNA Polymerase Gene Expression

T. Abe, H. Takaku, T. Yokota, 2001, Antiviral chemistry & chemotherapy.

Inhibition of influenza virus RNA polymerase by 5'-capped short RNA fragments.

K. Miura, H. Takaku, T. Yokota, 1998, Biochemical and biophysical research communications.

Use of the hexafluoro-2-butyl protecting group in the synthesis of DNA fragments via the phosphoramidite approach on solid supports

H. Takaku, Sung-Gug Kim, K. Eida, 1995 .

Use of 1,1,1,3,3,3-hexafluoro-2-propyl protecting group in the synthesis of dna fragments via phosphoramidite intermediates

H. Takaku, Tetsuo Watanabe, S. Hamamoto, 1988 .

Use of the 2-(2-Pyridyl)Ethyl Protecting Group in the Synthesis of DNA Fragments via Phosphoramidite Intermediates

H. Takaku, Tetsuo Watanabe, S. Hamamoto, 1987 .

Inhibition of influenza virus replication in cultured cells by RNA‐cleaving DNA enzyme

H. Takaku, N. Hamada, Y. Imamura, 2000, FEBS letters.

Uptake by dietary exposure and elimination of aflatoxins in muscle and liver of rainbow trout (Oncorhynchus mykiss).

Hisashi Yamada, H. Takaku, M. Yamashita, 2011, Journal of agricultural and food chemistry.

Specific inhibition of HIV-1 gene expression by double-stranded RNA.

N. Miyano-Kurosaki, H. Takaku, E. Nakajima, 2001, Nucleic acids research. Supplement.

RNA Interference Targeted to the Conserved Dimerization Initiation Site (DIS) of HIV-1 Restricts Virus Escape Mutation

N. Miyano-Kurosaki, H. Takaku, Ryuichi Sugiyama, 2009, Journal of biochemistry.

Site-specific cleavage of tRNA by imidazole and/or primary amine groups bound at the 5'-end of oligodeoxyribonucleotides.

H. Gouzu, H. Takaku, K. Takai, 1998, Biochimica et biophysica acta.

Mechanism of drug resistance of hemagglutinin of influenza virus and potent scaffolds inhibiting its function.

M. Tashiro, N. Yamamoto, H. Takaku, 2012, ACS chemical biology.

Solution structure of an RNA fragment with the P7/P9.0 region and the 3'-terminal guanosine of the tetrahymena group I intron.

Gota Kawai, Satoru Watanabe, Shigeyuki Yokoyama, 2002, RNA.

RNAi expression mediated inhibition of HCV replication.

K. Shimotohno, H. Hamazaki, N. Miyano-Kurosaki, 2004, Nucleic Acids Symposium Series.

A NEW CLASS OF ANTI-HIV-1 OLIGONUCLEOTIDE TARGETED TO THE POLYPURINE TRACT OF VIRAL RNA

H. Takaku, Takashi Hiratou, Naoko Miyano-Kurosaki, 2001, Nucleosides, nucleotides & nucleic acids.

Inhibition of Influenza Virus Replication in MDCK Cells by Circular Dumbbell RNA/DNA Chimeras with Closed Alkyl Loop Structures

T. Abe, H. Hamazaki, H. Takaku, 2002 .

Identification of amino acid residues in HIV‐1 reverse transcriptase that are critical for the proteolytic processing of Gag–Pol precursors

H. Nishitsuji, H. Takaku, M. Yokoyama, 2011, FEBS letters.

Recognition of a bulged RNA by peptides derived from the influenza NS1 protein.

G. Kawai, H. Takaku, T. Someya, 2008, Journal of biochemistry.

The interaction between human initiation factor eIF3 subunit c and heat-shock protein 90: a necessary factor for translation mediated by the hepatitis C virus internal ribosome entry site.

K. Shimotohno, H. Nishitsuji, H. Takaku, 2012, Virus research.

Importance of purine-pyridine hydroxyl and purine amino groups for hammerhead ribozyme cleavage

S. Yokoyama, H. Takaku, Hiroaki Tanaka, 1994 .

HIV-1 Gag-Virus-Like Particles Induce Natural Killer Cell Immune Responses via Activation and Maturation of Dendritic Cells

Tomoyuki Suzuki, H. Takaku, M. O. Chang, 2011, Journal of Innate Immunity.

Role of the zinc fingers of HIV-1 nucleocapsid protein in maturation of genomic RNA.

R. Gorelick, G. Kawai, Y. Koyanagi, 2003, Journal of Biochemistry (Tokyo).

INHIBITION OF HIV-1 REPLICATION BY THE CRE-LOXP HAMMERHEAD RIBOZYME

H. Takaku, H. Takeuchi, Y. Habu, 2001, Nucleosides, nucleotides & nucleic acids.

Inhibition of human immunodeficiency virus type 1 replication by P‐stereodefined oligo(nucleoside phosphorothioate)s in a long‐term infection model

W. Stec, H. Takaku, H. Takeuchi, 2002, FEBS letters.

Recombinant baculovirus expressing the FrC-OVA protein induces protective antitumor immunity in an EG7-OVA mouse model

Tomoyuki Suzuki, H. Takaku, M. O. Chang, 2019, Journal of biological engineering.

Gene silencing by the tRNA maturase tRNase ZL under the direction of small-guide RNA

M. Tamura, H. Takaku, M. Nashimoto, 2007, Gene Therapy.

Specificity of priming reaction of HIV-1 reverse transcriptase, 2'-OH or 3'-OH.

S. Inouye, M. Inouye, M. Roth, 1994, The Journal of biological chemistry.

A new role for PGA1 in inhibiting hepatitis C virus-IRES-mediated translation by targeting viral translation factors.

Y. Shimizu, K. Shimotohno, G. Kawai, 2015, Antiviral research.

A NEW CLASS OF ANTI-HIV-1 OLIGONUCLEOTIDE TARGETED TO THE POLYPURINE TRACT OF VIRAL RNA

H. Takaku, H. Gushima, T. Hiratou, 2001 .

A novel single-stranded DNA enzyme expression system using HIV-1 reverse transcriptase.

H. Takaku, A. Kusunoki, N. Miyano-kurosaki, 2003, Biochemical and biophysical research communications.

Long-term transgene expression and inhibition of HIV-1 replication by a Cre/loxP-EBNA-1/oriP HIV-1-dependent ribozyme vector: Applications for HIV-1 gene therapy

H. Takaku, Y. Habu, Takashi Nagawa, 2006, Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research.

Heat Shock Protein 70 Inhibits HIV-1 Vif-mediated Ubiquitination and Degradation of APOBEC3G*

A. Ryo, H. Nishitsuji, H. Takaku, 2011, The Journal of Biological Chemistry.

Short-hairpin RNAs synthesized by T7 phage polymerase do not induce interferon

H. Takaku, K. Yamaguchi, Y. Habu, 2008, Nucleic Acids Research.

Effective inhibition of HIV-1 replication in cultured cells by external guide sequences and ribonuclease P.

H. Takaku, J. Barnor, M. Kitano, 2004, Bioorganic & medicinal chemistry letters.

ATP1B3 Protein Modulates the Restriction of HIV-1 Production and Nuclear Factor κ Light Chain Enhancer of Activated B Cells (NF-κB) Activation by BST-2*

H. Nishitsuji, H. Takaku, M. Abe, 2015, The Journal of Biological Chemistry.

5-Chloro-8-quinolyl group as high efficient phosphate protecting group for the synthesis of oligoribonucleotides

H. Takaku, T. Hata, R. Yamaguchi, 1979 .

Infectivity of Hepatitis C Virus Is Influenced by Association with Apolipoprotein E Isoforms

Y. Shimizu, K. Shimotohno, T. Wakita, 2010, Journal of Virology.

Anti-human immunodeficiency virus type 1 activity of phosphorothioate analogs of oligodeoxynucleotides: penetration and localization of oligodeoxynucleotides in HIV-1-infected MOLT-4 cells.

S. Kim, J. Shimada, H. Takaku, 1994, Nucleic acids research.

Synthesis and properties of a modified 2'-5'-adenylate trimer containing 2'-terminal 8-bromoadenosine.

H. Takaku, S. Yoshida, 1985, Nucleic acids symposium series.