W. Cairns

发表

Evaluation of Cell-Based Assays for Steroid Nuclear Receptors Delivered by Recombinant Baculoviruses

William C Clay, R. Katso, M. Caivano, 2005, Journal of biomolecular screening.

Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes.

T. Willson, J. Auwerx, P. Chambon, 2004, The Journal of investigative dermatology.

Sequencing and functional assessment of hPXR (NR1I2) variants in intrahepatic cholestasis of pregnancy

I. McLay, W. Cairns, E. Elias, 2008 .

Glucocorticoids Repress Transcription from a Negative Glucocorticoid Response Element Recognized by Two Homeodomain-containing Proteins, Pbx and Oct-1*

S. Okret, W. Cairns, N. Subramaniam, 1998, The Journal of Biological Chemistry.

Intestinal Detoxification Limits the Activation of Hepatic Pregnane X Receptor by Lithocholic Acid

P. Clements, J. Holder, M. Parker, 2010, Drug Metabolism and Disposition.

Raised hepatic bile acid concentrations during pregnancy in mice are associated with reduced farnesoid X receptor function

S. Taylor-Robinson, K. Schoonjans, L. Klomp, 2010, Hepatology.

Inhibition of gene expression by steroid hormone receptors via a negative glucocorticoid response element: evidence for the involvement of DNA-binding and agonistic effects of the antiglucocorticoid/antiprogestin RU486.

S. Okret, W. Cairns, C. Cairns, 1993, DNA and cell biology.

The identification a novel, selective, non-steroidal, functional glucocorticoid receptor antagonist.

Paul W Smith, S. Gul, M. Caivano, 2010, Bioorganic & medicinal chemistry letters.

Functional Interaction between Nucleosome Assembly Proteins and p300/CREB-Binding Protein Family Coactivators

N. Shikama, M. Krstic-Demonacos, N. L. La Thangue, 2000, Molecular and Cellular Biology.

Maternal diet and aging alter the epigenetic control of a promoter–enhancer interaction at the Hnf4a gene in rat pancreatic islets

Yoko Ito, Yoko Ito, C. Ling, 2011, Proceedings of the National Academy of Sciences.

The application of BacMam technology in nuclear receptor drug discovery.

R. Katso, J. Parham, J. P. Condreay, 2005, Biotechnology annual review.

Characterization of the Human Cytochrome P4502D6 Promoter

C. Wolf, W. Cairns, R. Wolf, 1996, The Journal of Biological Chemistry.

Assembly of a glucocorticoid receptor complex prior to DNA binding enhances its specific interaction with a glucocorticoid response element.

L. Poellinger, I. Pongratz, S. Okret, 1991, The Journal of biological chemistry.

Studies on the mechanism of glucocorticoid-mediated repression from a negative glucocorticoid response element from the bovine prolactin gene.

S. Okret, W. Cairns, N. Subramaniam, 1997, DNA and cell biology.

Activation of TRPV4 Channels (hVRL-2/mTRP12) by Phorbol Derivatives*

V. Flockerzi, B. Nilius, G. Droogmans, 2002, The Journal of Biological Chemistry.

Cloning and functional expression of a human orthologue of rat vanilloid receptor-1

S. Topp, P. Murdock, R. Prinjha, 2000, Pain.

A glucocorticoid-resistant rat hepatoma cell variant contains functional glucocorticoid receptor.

J. Gustafsson, S. Okret, W. Cairns, 1990, Journal of Biological Chemistry.

Characterization of the human HCN1 channel and its inhibition by capsazepine

C. Davies, P. Murdock, D. Owen, 2004, British journal of pharmacology.

Peroxisome Proliferator-Activated Receptor (PPAR)-β/δ Stimulates Differentiation and Lipid Accumulation in Keratinocytes

T. Willson, J. Auwerx, P. Chambon, 2004 .

The normal mechanisms of pregnancy-induced liver growth are not maintained in mice lacking the bile acid sensor Fxr.

D. Dormann, S. Milligan, K. Schoonjans, 2010, American journal of physiology. Gastrointestinal and liver physiology.

Heterogeneity in the 5′ untranslated region of the rat glucocorticoid receptor mRNA

J. Gustafsson, S. Okret, W. Cairns, 1993, The Journal of Steroid Biochemistry and Molecular Biology.

Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology.

A. Randall, W. Cairns, M. Gunthorpe, 2001, European journal of pharmacology.

Pharmacological assessment of the role of the glycine transporter GlyT-1 in mediating high-affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes

A. Brown, H. Herdon, W. Cairns, 2001, Neuropharmacology.

Cloning, functional characterisation and population analysis of a variant form of the human glycine type 2 transporter

H. Herdon, J. Terrett, W. Cairns, 1999, FEBS letters.

Raised hepatic bile acid concentrations during pregnancy in mice are associated with reduced farnesoid X receptor function

S. Taylor-Robinson, K. Schoonjans, L. Klomp, 2010, Hepatology.

Cloning and functional expression of a human orthologue of rat vanilloid receptor-1

S. Topp, P. Murdock, R. Prinjha, 2000, Pain.