Santosh Kumar

发表

Stopped-flow kinetic studies of poly(amidoamine) dendrimer-calf thymus DNA to form dendriplexes.

Debabrata Dey, S. Maiti, Santosh Kumar, 2013, The journal of physical chemistry. B.

A molecular-beacon-based screen for small molecule inhibitors of miRNA maturation.

Souvik Maiti, S. Maiti, Santosh Kumar, 2013, ACS chemical biology.

Morphological effects of G-quadruplex stabilization using a small molecule in zebrafish.

S. Sivasubbu, S. Maiti, Santosh Kumar, 2014, Biochemistry.

Dehydrogenation of the Indoline-Containing Drug 4-Chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide (Indapamide) by CYP3A4: Correlation with in Silico Predictions

Hao Sun, J. Halpert, Santosh Kumar, 2009, Drug Metabolism and Disposition.

Steroids Up-Regulate p66Shc Longevity Protein in Growth Regulation by Inhibiting Its Ubiquitination

M. Rajendran, P. Cheng, Santosh Kumar, 2011, PloS one.

Ligand Diversity of Human and Chimpanzee CYP3A4: Activation of Human CYP3A4 by Lithocholic Acid Results from Positive Selection

N. Oezguen, J. Halpert, L. Wojnowski, 2009, Drug Metabolism and Disposition.

ROLE OF CYTOCHROME B5 IN MODULATING PEROXIDE-SUPPORTED CYP3A4 ACTIVITY: EVIDENCE FOR A CONFORMATIONAL TRANSITION AND CYTOCHROME P450 HETEROGENEITY

J. Halpert, Santosh Kumar, D. Davydov, 2005, Drug Metabolism and Disposition.

Role of Cytochrome b 5 in Modulating Peroxide-supported CYP 3 A 4 Activity : Evidence for a Conformational Transition and P 450 Heterogeneity

J. Halpert, Santosh Kumar, D. Davydov, 2005 .

ROLE OF CYTOCHROME B 5 IN MODULATING PEROXIDE-SUPPORTED CYP 3 A 4 ACTIVITY : EVIDENCE FOR A CONFORMATIONAL TRANSITION AND CYTOCHROME P 450 HETEROGENEITY

J. Halpert, Santosh Kumar, D. Davydov, 2005 .

Mycobacterium tuberculosis survival in J774A.1 cells is dependent on MenJ moonlighting activity, not its enzymatic activity.

M. Gonzalez-Juarrero, Santosh Kumar, D. Crick, 2020, ACS infectious diseases.

A2B adenosine receptor antagonists: Design, synthesis and biological evaluation of novel xanthine derivatives.

G. Bedse, S. Menon, A. Chugh, 2017, European journal of medicinal chemistry.

Unlocking G-quadruplex: Effect of unlocked nucleic acid on G-quadruplex stability.

S. Maiti, Santosh Kumar, T. Agarwal, 2011, Biochimie.

Investigation of the role of cytochrome P450 2B4 active site residues in substrate metabolism based on crystal structures of the ligand-bound enzyme.

J. Halpert, Hong Liu, Santosh Kumar, 2006, Archives of biochemistry and biophysics.

Human telomeric RNA G-quadruplex response to point mutation in the G-quartets.

Satyaprakash Pandey, S. Maiti, Santosh Kumar, 2015, The journal of physical chemistry. B.

Identification and Analysis of Conserved Sequence Motifs in Cytochrome P450 Family 2

W. Braun, N. Oezguen, B. K. Muralidhara, 2008, Journal of Biological Chemistry.

Decavanadate Inhibits Mycobacterial Growth More Potently Than Other Oxovanadates

Santosh Kumar, D. Crick, D. Crans, 2018, Front. Chem..

Characterization of glyceraldehyde-3-phosphate dehydrogenase as a novel transferrin receptor.

M. Raje, Santosh Kumar, C. I. Raje, 2012, The international journal of biochemistry & cell biology.

INSILICO MICROARRAY ANALYSIS FOR HELICOBACTER PYLORI USING GENE EXPRESSION DATA

S. Vaishnavi, Santosh Kumar, P. Srivastava, 2010 .

Allosteric mechanisms in P450eryF probed with 1-pyrenebutanol, a novel fluorescent substrate.

J. Halpert, Santosh Kumar, D. Davydov, 2002, Biochemical and biophysical research communications.

Identification of a Novel Laser Dye Substrate of Mammalian Cytochromes P450: Application in Rapid Kinetic Analysis, Inhibitor Screening, and Directed Evolution

Santosh Kumar, 2007, Journal of biomolecular screening.

The Effect of N-acetylation and N-methylation of Lysine Residue of Tat Peptide on its Interaction with HIV-1 TAR RNA

S. Maiti, Santosh Kumar, 2013, PloS one.

Specificity of RSG-1.2 Peptide Binding to RRE-IIB RNA Element of HIV-1 over Rev Peptide Is Mainly Enthalpic in Origin

S. Maiti, Santosh Kumar, D. Bose, 2011, PloS one.

MUTATIONS OUTSIDE OF THE ACTIVE SITE ENHANCE THE METABOLISM OF SEVERAL SUBSTRATES, INCLUDING THE ANTICANCER PRODRUGS CYCLOPHOSPHAMIDE AND IFOSFAMIDE*

D. Waxman, J. Halpert, Santosh Kumar, 2005 .

Analyzing different acetyl co-A metabolizing enzymes as potential drug targets against Mycobacterium tuberculosis.

S. Akhtar, Santosh Kumar, D. Sarkar, 2015 .

In the sense of transcription regulation by G-quadruplexes: asymmetric effects in sense and antisense strands.

S. Maiti, Santosh Kumar, T. Agarwal, 2014, Biochemistry.

Dehydrogenation of the Indoline-Containing Drug, Indapamide, by CYP3A4: Correlation with in silico Predictions

Hao Sun, J. Halpert, Santosh Kumar, 2008 .

Decreased Susceptibility of the Cytochrome P450 2B6 Variant K262R to Inhibition by Several Clinically Important Drugs

J. Halpert, Santosh Kumar, Jyothi C. Talakad, 2009, Drug Metabolism and Disposition.

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J. Halpert, Santosh Kumar, Jyothi C. Talakad, 2008 .

Mechanism of Fluorinated Anthranilate-Induced Growth Inhibition in Mycobacterium tuberculosis.

J. Lott, Santosh Kumar, D. Crick, 2019, ACS infectious diseases.

Superior HIV‐1 TAR Binders with Conformationally Constrained R52 Arginine Mimics in the Tat(48–57) Peptide

S. Maiti, Santosh Kumar, D. Sengupta, 2018, ChemMedChem.

Oleic Acid Induces MiR-7 Processing through Remodeling of Pri-MiR-7/Protein Complex

Santosh Kumar, G. Michlewski, Angela Downie Ruiz Velasco, 2017, Journal of molecular biology.

Secreted glyceraldehye-3-phosphate dehydrogenase is a multifunctional autocrine transferrin receptor for cellular iron acquisition.

M. Raje, Santosh Kumar, Vikas A. Tillu, 2013, Biochimica et biophysica acta.

The multifunctional glycolytic protein glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a novel macrophage lactoferrin receptor.

M. Raje, Santosh Kumar, P. Rawat, 2012, Biochemistry and cell biology = Biochimie et biologie cellulaire.

The Macrophage Cell Surface Glyceraldehyde-3-phosphate Dehydrogenase Is a Novel Transferrin Receptor*

M. Raje, Santosh Kumar, J. Nanda, 2007, Journal of Biological Chemistry.

Understanding the effect of locked nucleic acid and 2'-O-methyl modification on the hybridization thermodynamics of a miRNA-mRNA pair in the presence and absence of AfPiwi protein.

S. Maiti, Santosh Kumar, K. Mapa, 2014, Biochemistry.

Moonlighting cell-surface GAPDH recruits apotransferrin to effect iron egress from mammalian cells

M. Raje, A. S. Chauhan, Santosh Kumar, 2014, Journal of Cell Science.

Rational engineering of cytochromes P450 2B6 and 2B11 for enhanced stability: Insights into structural importance of residue 334.

J. Halpert, Santosh Kumar, D. Davydov, 2010, Archives of biochemistry and biophysics.

Effect of different arginine methylations on the thermodynamics of Tat peptide binding to HIV-1 TAR RNA.

S. Maiti, Santosh Kumar, 2013, Biochimie.

Differential time-dependent inactivation of P450 3A4 and P450 3A5 by raloxifene: a key role for C239 in quenching reactive intermediates.

L. Wienkers, D. Rock, J. Halpert, 2007, Chemical research in toxicology.

Effi cient Experimental Design and Analysis Strategies for the Detection of Differential Expression Using RNA-Sequencing

Santosh Kumar, Santosh Kumar, 2014 .

Exosomes: Tunable Nano Vehicles for Macromolecular Delivery of Transferrin and Lactoferrin to Specific Intracellular Compartment.

Manoj Kumar, M. Kumar, M. Raje, 2016, Journal of biomedical nanotechnology.

Role of microRNAs in cardiovascular diseases and their therapeutic implications

Santosh Kumar, H. Suryawanshi, 2019, AGO-Driven Non-Coding RNAs.

Zinc regulates the activity of kinase-phosphatase pair (BasPrkC/BasPrpC) in Bacillus anthracis

S. Maiti, Andaleeb Sajid, G. Arora, 2013, BioMetals.

Mycobacterial MenJ: An Oxidoreductase Involved in Menaquinone Biosynthesis.

J. Lott, A. Upadhyay, Santosh Kumar, 2018, ACS chemical biology.

Directed evolution of mammalian cytochromes P450 for investigating the molecular basis of enzyme function and generating novel biocatalysts

J. Halpert, Hong Liu, Santosh Kumar, 2005, Biochemical and biophysical research communications.

Directed Evolution of Mammalian Cytochrome P450 2B1

D. Waxman, J. Halpert, Santosh Kumar, 2005, Journal of Biological Chemistry.

A Rational Approach to Re-engineer Cytochrome P450 2B1 Regioselectivity Based on the Crystal Structure of Cytochrome P450 2C5*

J. Halpert, Hong Liu, Santosh Kumar, 2003, The Journal of Biological Chemistry.

Re-engineering cytochrome P450 2B11dH for enhanced metabolism of several substrates including the anti-cancer prodrugs cyclophosphamide and ifosfamide.

D. Waxman, J. Halpert, Hong Liu, 2007, Archives of biochemistry and biophysics.

Engineering of Cytochrome P450 3A4 for Enhanced Peroxide-Mediated Substrate Oxidation Using Directed Evolution and Site-Directed Mutagenesis

J. Halpert, Hong Liu, Santosh Kumar, 2006, Drug Metabolism and Disposition.

Engineering mammalian cytochrome P450 2B1 by directed evolution for enhanced catalytic tolerance to temperature and dimethyl sulfoxide.

B. K. Muralidhara, J. Halpert, Hong Liu, 2006, Protein engineering, design & selection : PEDS.

Polyplex formation between PEGylated linear cationic block copolymers and DNA: equilibrium and kinetic studies.

Debabrata Dey, S. Maiti, Santosh Kumar, 2014, The journal of physical chemistry. B.

Analysis of Cytochrome P450 Conserved Sequence Motifs between Helices E and H: Prediction of Critical Motifs and Residues in Enzyme Functions

N. Oezguen, Santosh Kumar, 2011, Journal of drug metabolism & toxicology.

Thermodynamics and solvation dynamics of BIV TAR RNA-Tat peptide interaction.

S. Maiti, Santosh Kumar, Teena Goel, 2013, Molecular bioSystems.

The structure of Rv2372c identifies an RsmE-like methyltransferase from Mycobacterium tuberculosis.

Atul Kumar, Santosh Kumar, B. Taneja, 2014, Acta crystallographica. Section D, Biological crystallography.

Design and synthesis of novel xanthine derivatives as potent and selective A2B adenosine receptor antagonists for the treatment of chronic inflammatory airway diseases.

S. Menon, A. Chugh, V. Karande, 2017, European journal of medicinal chemistry.

Structural and thermodynamic consequences of 1-(4-chlorophenyl)imidazole binding to cytochrome P450 2B4.

B. K. Muralidhara, J. Halpert, C. Stout, 2007, Biochemistry.

Rational Engineering of Human Cytochrome P450 2B6 for Enhanced Expression and Stability: Importance of a Leu264→Phe Substitution

B. K. Muralidhara, J. Halpert, Yonghong Zhao, 2007, Molecular Pharmacology.

Purification and characterization of glyceraldehyde-3-phosphate-dehydrogenase (GAPDH) from pea seeds.

M. Raje, Santosh Kumar, V. Boradia, 2016, Protein Expression and Purification.

An electrostatically driven conformational transition is involved in the mechanisms of substrate binding and cooperativity in cytochrome P450eryF.

J. Halpert, Santosh Kumar, D. Davydov, 2004, Biochemistry.