P. Digard

P. Simmonds, P. Digard, Donald B. Smith, 2016, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

An alternative AUG codon in segment 5 of the 2009 pandemic influenza A virus is a swine-derived virulence motif

P. Beard, J. Nguyen-Van-Tam, P. Digard, 2019, bioRxiv.

Functional domains of the influenza A virus PB2 protein: identification of NP- and PB1-binding sites.

P. Digard, D. Elton, E. Poole, 2004, Virology.

Face Coverings, Aerosol Dispersion and Mitigation of Virus Transmission Risk

I. M. Viola, F. Denison, P. Digard, 2020, IEEE Open Journal of Engineering in Medicine and Biology.

Inhibition of the influenza virus RNA-dependent RNA polymerase by antisera directed against the carboxy-terminal region of the PB2 subunit.

S. Inglis, C. Cianci, M. Krystal, 1996, The Journal of general virology.

Nucleozin Targets Cytoplasmic Trafficking of Viral Ribonucleoprotein-Rab11 Complexes in Influenza A Virus Infection

R. Kao, M. Amorim, P. Digard, 2013, Journal of Virology.

Complex formation between influenza virus polymerase proteins expressed in Xenopus oocytes

S. Inglis, P. Digard, V. Blok, 1989, Virology.

The influenza virus nucleoprotein

P. Digard, A. Portela, 2002 .

Increased amounts of the influenza virus nucleoprotein do not promote higher levels of viral genome replication.

M. Amorim, P. Digard, D. Elton, 2004, The Journal of general virology.

‘Genome gating’; polarized intranuclear trafficking of influenza virus RNPs

M. Amorim, P. Digard, D. Elton, 2005, Biology Letters.

Mutational Analysis of cis-Acting RNA Signals in Segment 7 of Influenza A Virus

J. Gog, E. Hutchinson, P. Digard, 2008, Journal of Virology.

Budding of filamentous and non-filamentous influenza A virus occurs via a VPS4 and VPS28-independent pathway.

P. Digard, A. Stuart, D. Elton, 2009, Virology.

Nuclear dynamics of influenza A virus ribonucleoproteins revealed by live-cell imaging studies

J. C. von Kirchbach, E. Fodor, P. Digard, 2009, Virology.

Comprehensive Characterization of Transcriptional Activity during Influenza A Virus Infection Reveals Biases in Cap-Snatching of Host RNA Sequences

Piero Carninci, Y. Hayashizaki, D. Hume, 2020, Journal of Virology.

Comprehensive characterisation of molecular host-pathogen interactions in influenza A virus-infected human macrophages

Piero Carninci, Y. Hayashizaki, D. Hume, 2019, bioRxiv.

Elevation of CpG frequencies in influenza A genome attenuates pathogenicity but enhances host response to infection

P. Klenerman, P. Simmonds, P. Beard, 2016, eLife.

Characterisation of influenza A viruses with mutations in segment 5 packaging signals

E. Hutchinson, P. Digard, H. Wise, 2009, Vaccine.

Codon conservation in the influenza A virus genome defines RNA packaging signals

J. Gog, J. C. von Kirchbach, N. Escriou, 2007, Nucleic acids research.

Expression of HIV-1 Vpu Leads to Loss of the Viral Restriction Factor CD317/Tetherin from Lipid Rafts and Its Enhanced Lysosomal Degradation

G. Banting, P. Gleeson, P. Digard, 2013, PloS one.

Studies of an Influenza A Virus Temperature-Sensitive Mutant Identify a Late Role for NP in the Formation of Infectious Virions

E. Medcalf, E. Hutchinson, P. Digard, 2008, Journal of Virology.

Mutation of Influenza A Virus PA-X Decreases Pathogenicity in Chicken Embryos and Can Increase the Yield of Reassortant Candidate Vaccine Viruses

P. Beard, J. Taubenberger, P. Digard, 2018, Journal of Virology.

Mutation of Influenza A Virus PA-X Decreases Pathogenicity in Chicken Embryos and Can Increase the Yield of Reassortant Candidate Vaccine Viruses

P. Beard, J. Taubenberger, P. Digard, 2018, Journal of Virology.

The PB2-E627K Mutation Attenuates Viruses Containing the 2009 H1N1 Influenza Pandemic Polymerase

J. Taubenberger, G. L. Allen, P. Digard, 2010, mBio.

Constitutive TRIM22 expression within the respiratory tract identifies tissue-specific and cell-type dependent intrinsic immune barriers to influenza A virus infection

J. Stewart, C. Boutell, S. McFarlane, 2019, bioRxiv.

Using Species a Rotavirus Reverse Genetics to Engineer Chimeric Viruses Expressing SARS-CoV-2 Spike Epitopes

P. Digard, W. Tan, A. Borodavka, 2022, Journal of virology.

Pathogenesis of Ebola and Marburg viruses.

R. Randall, P. Digard, S. Nichol, 2005 .

Influenza--time to target the host?

J. Baillie, P. Digard, 2013, The New England journal of medicine.

Using Species a Rotavirus Reverse Genetics to Engineer Chimeric Viruses Expressing SARS-CoV-2 Spike Epitopes

Joanne M Stevens, P. Digard, W. Tan, 2022, Journal of virology.

Engineering a Vaccine Platform using Rotavirus A to Express SARS-CoV-2 Spike Epitopes

P. Digard, A. Borodavka, J. Stevens, 2022, bioRxiv.

Polymerization activity of an alpha-like DNA polymerase requires a conserved 3'-5' exonuclease active site

D. Coen, K. Weißhart, D. Knipe, 1991, Molecular and cellular biology.

Personalised 3D printed respirators for healthcare workers during the COVID-19 pandemic

Alistair C. McConnell, A. Stokes, J. Norrie, 2022, Frontiers in Medical Technology.

PA-X antagonises MAVS-dependent accumulation of early type I interferon messenger RNAs during influenza A virus infection

J. Rehwinkel, P. Digard, Nikki Smith, 2019, Scientific Reports.

TRIM25 inhibits influenza A virus infection, destabilizes viral mRNA, but is redundant for activating the RIG-I pathway

P. Digard, Nikki Smith, E. Gaunt, 2022, Nucleic acids research.

Dynamics of Inﬂuenza Virus Infection and Pathology (cid:1)

J. Gog, B. Grenfell, J. Wood, 2010 .

Mutational Analysis of cis -Acting RNA Signals in Segment 7 of Inﬂuenza A Virus (cid:1)

J. Gog, E. Hutchinson, P. Digard, 2008 .

Segment 2 from influenza A(H1N1)pdm09 viruses confers temperature sensitive HA yield on candidate vaccine virus growth in eggs that is complemented by PB2 701D

P. Digard, O. Engelhardt, J. McCauley, 2019, bioRxiv.

Segment 2 from influenza A(H1N1) 2009 1 pandemic viruses confers temperature sensitive 2 HA yield on candidate vaccine virus growth in 3 eggs that can be epistatically complemented by 4 PB2 701D 5

J. McCauley, P. Digard, O. Engelhardt, 2019 .

Role of the Rab11 pathway in negative-strand virus assembly.

P. Digard, A. Stuart, M. Mccaffrey, 2012, Biochemical Society transactions.

A net +1 frameshift permits synthesis of thymidine kinase from a drug-resistant herpes simplex virus mutant.

D. Coen, P. Digard, E. Pelosi, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Release of filamentous and spherical influenza A virus is not restricted by tetherin.

S. Neil, G. Banting, P. Digard, 2012, The Journal of general virology.

Accessory Gene Products of Influenza A Virus.

P. Digard, S. Lycett, E. Gaunt, 2020, Cold Spring Harbor perspectives in medicine.

PA-X is an avian virulence factor in H9N2 avian influenza virus

T. Peacock, P. Digard, J. Sealy, 2020, bioRxiv.

Inhibition of the influenza virus RNA-dependent RNA polymerase by antisera directed against the carboxy-terminal region of the PB 2 subunit

S. Inglis, C. Cianci, M. Krystal, 2007 .

The Rab11 Pathway Is Required for Inﬂuenza A Virus Budding and Filament Formation (cid:1)

P. Digard, A. Stuart, E. Bruce, 2010 .

CpG dinucleotide enrichment in the influenza A virus genome as a live attenuated vaccine development strategy

P. Simmonds, P. Digard, L. Vervelde, 2022, bioRxiv.

Ribosomal frameshifting used in influenza A virus expression occurs within the sequence UCC_UUU_CGU and is in the +1 direction

S. Napthine, J. Taubenberger, A. Firth, 2012, Open Biology.

Effects of mutations in the effector domain of influenza A virus NS1 protein

M. Amorim, P. Digard, H. Wise, 2018, BMC Research Notes.

A chicken bioreactor for efficient production of functional cytokines

D. Hume, A. Sherman, H. Sang, 2018, BMC Biotechnology.

Effectiveness of Common Household Cleaning Agents in Reducing the Viability of Human Influenza A/H1N1

J. Nguyen-Van-Tam, P. Digard, P. Powell, 2010, PloS one.

Ribosomal frameshifting used in influenza A virus expression occurs within the sequence UCC_UUU_CGU and is in the +1 direction

S. Napthine, J. Taubenberger, A. Firth, 2012, Open Biology.

Edinburgh Research Explorer Permissive and Restricted Virus Infection of Murine Embryonic Stem Cells

J. Haas, P. Kellam, D. Goulding, 2018 .

The genetics of virus particle shape in equine influenza A virus

J. Daly, S. Macrae, P. Digard, 2013, Influenza and other respiratory viruses.

Contribution of Segment 3 to the Acquisition of Virulence in Contemporary H9N2 Avian Influenza Viruses

T. Peacock, P. Digard, J. Sealy, 2020, Journal of Virology.

Human γδ T Cells: A Lymphoid Lineage Cell Capable of Professional Phagocytosis1

Wutian Wu, D. Goldblatt, K. Gustafsson, 2009, The Journal of Immunology.

Packaging signals in the 5'-ends of influenza virus PA, PB1, and PB2 genes as potential targets to develop nucleic-acid based antiviral molecules.

I. Donatelli, P. Digard, S. Giannecchini, 2011, Antiviral research.

Constitutive TRIM22 Expression in the Respiratory Tract Confers a Pre-Existing Defence Against Influenza A Virus Infection

J. Stewart, C. Boutell, S. McFarlane, 2021, Frontiers in Cellular and Infection Microbiology.

Constitutive TRIM 22 expression within the respiratory tract identifies 2 tissue-specific and cell-type dependent intrinsic immune barriers to 3 influenza A virus infection 4

C. Boutell, S. McFarlane, M. Carroll, 2019 .

A comparative analysis of host responses to avian influenza infection in ducks and chickens highlights a role for the interferon-induced transmembrane proteins in viral resistance

D. Burt, R. Webster, D. Burt, 2015, BMC Genomics.

Dynamics of Influenza Virus Infection and Pathology

Ann Cullinane, Julia R. Gog, Bryan T. Grenfell, 2010, Journal of Virology.

Engineered Recombinant Single Chain Variable Fragment of Monoclonal Antibody Provides Protection to Chickens Infected with H9N2 Avian Influenza

P. Digard, J. Sealy, Pengxiang Chang, 2020, Vaccines.

Vaccinia Virus Uses Retromer-Independent Cellular Retrograde Transport Pathways To Facilitate the Wrapping of Intracellular Mature Virions during Virus Morphogenesis

Tali Pechenick Jowers, I. Haga, P. Beard, 2016, Journal of Virology.

Quantitative proteomics using SILAC coupled to LC-MS/MS reveals changes in the nucleolar proteome in influenza A virus-infected cells.

D. Matthews, J. Hiscox, P. Digard, 2010, Journal of proteome research.

Explorer Human Cytomegalovirus Inhibitor AL 18 Also Possesses Activity against Influenza A and B Viruses

L. Goracci, G. Cruciani, G. Palù, 2017 .

Human Cytomegalovirus Inhibitor AL18 Also Possesses Activity against Influenza A and B Viruses

L. Goracci, G. Cruciani, G. Palù, 2012, Antimicrobial Agents and Chemotherapy.

Nuclear Export of Influenza A Virus mRNAs Requires Ongoing RNA Polymerase II Activity

M. Amorim, P. Digard, R. M. Dalton, 2007, Traffic.

Temperature sensitive influenza A virus genome replication results from low thermal stability of polymerase-cRNA complexes

E. Medcalf, M. Amorim, P. Digard, 2006, Virology Journal.

Lipid Raft‐Dependent Targeting of the Influenza A Virus Nucleoprotein to the Apical Plasma Membrane

M. Amorim, P. Digard, Marlene J. Carrasco, 2004, Traffic.

Influenza A virus and the cell nucleus.

M. Amorim, P. Digard, 2006, Vaccine.

Explorer The extreme C terminus of herpes simplex virus DNA polymerase is crucial for functional interaction with processivity factor UL 42 and for viral replication

D. Coen, K. Weißhart, P. Digard, 2017 .

Secondary Structure and Structure-Activity Relationships of Peptides Corresponding to the Subunit Interface of Herpes Simplex Virus DNA Polymerase*

D. Coen, M. Weiss, P. Digard, 2000, The Journal of Biological Chemistry.

Functional analysis of the herpes simplex virus UL42 protein

D. Coen, P. Digard, L. Pirrit, 1993, Journal of virology.

The extreme C terminus of herpes simplex virus DNA polymerase is crucial for functional interaction with processivity factor UL42 and for viral replication

D. Coen, K. Weißhart, P. Digard, 1993, Journal of virology.

An analysis of the biological properties of monoclonal antibodies against glycoprotein D of herpes simplex virus and identification of amino acid substitutions that confer resistance to neutralization.

D. Hancock, P. Digard, A. Minson, 1986, The Journal of general virology.

A functional link between the actin cytoskeleton and lipid rafts during budding of filamentous influenza virions.

D. Ellis, P. Digard, J. McCauley, 2002, Virology.

Activation of influenza virus RNA polymerase by the 5' and 3' terminal duplex of genomic RNA.

P. Digard, K. Klumpp, L. Tiley, 2003, Nucleic acids research.

Definition of the minimal viral components required for the initiation of unprimed RNA synthesis by influenza virus RNA polymerase.

P. Digard, D. Elton, L. Tiley, 2002, Nucleic acids research.

Upstream translation initiation expands the coding capacity of segmented negative-strand RNA viruses

I. Brierley, J. Baillie, A. Firth, 2019, bioRxiv.

Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection

Paul J. Hoover, N. Hacohen, J. Doench, 2020, Nature Communications.

Edinburgh Research Explorer Interaction of the influenza virus nucleoprotein with the cellular CRM1-mediated nuclear export pathway

J. McCauley, P. Digard, D. Elton, 2022 .

CRM 1-Mediated Nuclear Export Pathway Nucleoprotein with the Cellular Interaction of the Influenza Virus

J. McCauley, P. Digard, D. Elton, 2000 .

Modulation of Nuclear Localization of the Influenza Virus Nucleoprotein through Interaction with Actin Filaments

E. Medcalf, P. Digard, D. Elton, 1999, Journal of Virology.

A LC3-Interacting Motif in the Influenza A Virus M2 Protein Is Required to Subvert Autophagy and Maintain Virion Stability

F. Randow, P. Digard, A. Stuart, 2014, Cell host & microbe.

Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection

Paul J. Hoover, John G Doench, N. Hacohen, 2020, Nature Communications.

Face Coverings, Aerosol Dispersion and Mitigation of Virus Transmission Risk

I. M. Viola, F. Denison, P. Digard, 2020, IEEE Open Journal of Engineering in Medicine and Biology.

Face coverings and respiratory tract droplet dispersion

I. M. Viola, J. Seckl, P. Digard, 2020, Royal Society Open Science.

A Rab11- and Microtubule-Dependent Mechanism for Cytoplasmic Transport of Influenza A Virus Viral RNA

M. Amorim, P. Digard, A. Stuart, 2011, Journal of Virology.

The Rab11 Pathway Is Required for Influenza A Virus Budding and Filament Formation

P. Digard, A. Stuart, Paul Digard, 2010, Journal of Virology.

Heterogeneity of Early Host Response to Infection with Four Low-Pathogenic H7 Viruses with a Different Evolutionary History in the Field

Jacqueline Smith, Y. Berhane, P. Digard, 2021, Viruses.

Explorer Permissive and Restricted Virus Infection of Murine Embryonic Stem Cells

J. Haas, P. Kellam, D. Goulding, 2017 .

Permissive and restricted virus infection of murine embryonic stem cells

J. Haas, P. Kellam, D. Goulding, 2012, The Journal of general virology.

Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection

Robyn M. Kaake, N. Krogan, J. Yewdell, 2020, Cell.

Compositional biases in RNA viruses: Causes, consequences and applications

P. Digard, E. Gaunt, 2021, Wiley interdisciplinary reviews. RNA.

Identification of the domains of the influenza A virus M1 matrix protein required for NP binding, oligomerization and incorporation into virions

E. Medcalf, P. Digard, D. Elton, 2007, The Journal of general virology.

An Overlapping Protein-Coding Region in Influenza A Virus Segment 3 Modulates the Host Response

K. Walters, J. F. Atkins, J. Taubenberger, 2012, Science.

The influence of viral coding sequences on pestivirus IRES activity reveals further parallels with translation initiation in prokaryotes.

R. Jackson, A. Kaminski, P. Digard, 2002, RNA.

Mutational analysis of DNA polymerase substrate recognition and subunit interactions using herpes simplex virus as prototype.

D. Coen, P. Digard, W. Bebrin, 1995, Methods in enzymology.

A Complicated Message: Identification of a Novel PB1-Related Protein Translated from Influenza A Virus Segment 2 mRNA

Wendy S. Barclay, W. Barclay, E. Anderson, 2009, Journal of Virology.

The cellular localization of avian influenza virus PB1-F2 protein alters the magnitude of IFN2 promoter and NFκB-dependent promoter antagonism in chicken cells.

S. Goodbourn, W. Barclay, P. Digard, 2019, The Journal of general virology.

Influence of PB2 host-range determinants on the intranuclear mobility of the influenza A virus polymerase

M. Mura, W. Barclay, P. Digard, 2011, The Journal of general virology.

TRIM25 inhibits Influenza A infection by destabilising its mRNA and is redundant for the RIG-I pathway

P. Digard, E. Gaunt, G. Michlewski, 2021 .

An alternative AUG codon that produces an N-terminally extended form of the influenza A virus NP is a virulence factor for a swine-derived virus

P. Beard, J. Nguyen-Van-Tam, P. Digard, 2019 .

Overlapping signals for translational regulation and packaging of influenza A virus segment 2

J. Gog, J. Taubenberger, E. Anderson, 2011, Nucleic acids research.

Using SILAC and quantitative proteomics to investigate the interactions between viral and host proteomes

D. Matthews, J. Barr, J. Hiscox, 2012, Proteomics.

The influenza virus nucleoprotein: a multifunctional RNA-binding protein pivotal to virus replication.

P. Digard, A. Portela, 2002, The Journal of general virology.

Edinburgh Research Explorer Identification of amino acid residues of influenza virus nucleoprotein essential for RNA binding

P. Digard, D. Elton, L. Medcalf, 2022 .

Intra-genome variability in the dinucleotide composition of SARS-CoV-2

P. Digard, Finn E. Grey, E. Gaunt, 2020, bioRxiv.

The molecular basis of differential host responses to avian influenza viruses in avian species with differing susceptibility

D. Burt, Jacqueline Smith, P. Digard, 2023, Frontiers in Cellular and Infection Microbiology.

Staphylococcus aureus Lipase 1 Enhances Influenza A Virus Replication

P. Digard, S. Hussain, B. Dutia, 2020, mBio.

The PB 2E 627 K Mutation Attenuates Viruses Containing the 2009 H 1 N 1 Influenza Pandemic Polymerase

G. L. Allen, P. Digard, Ruixue Wang, 2017 .

Influenza A Virus NS1 Protein Promotes Efficient Nuclear Export of Unspliced Viral M1 mRNA

M. Amorim, P. Digard, H. Wise, 2017, Journal of Virology.

Individual influenza A virus mRNAs show differential dependence on cellular NXF1/TAP for their nuclear export

P. Digard, E. Read, 2010, The Journal of general virology.

Edinburgh Research Explorer Identification of a novel splice variant form of the influenza a virus m2 ion channel with an antigenically distinct ectodomain

Andrew E. Firth, Julia R. Gog, Ervin Fodor, 2022 .

Modelling the Structure and Dynamics of Biological Pathways

Tim Angus, Laura O'Hara, Tom C Freeman, 2016, PLoS biology.

Options for the control of influenza VI

Ervin Fodor, E. Fodor, P. Digard, 2008 .

The environmental deposition of influenza virus from patients infected with influenza A(H1N1)pdm09: Implications for infection prevention and control.

W. Lim, S. Cauchemez, J. Nguyen-Van-Tam, 2016, Journal of infection and public health.

Small molecule inhibitors of influenza A and B viruses that act by disrupting subunit interactions of the viral polymerase

Giorgio Palù, Gabriele Cruciani, Laura Goracci, 2012, Proceedings of the National Academy of Sciences.

Interaction of the influenza virus nucleoprotein with F-actin

E. Medcalf, P. Digard, D. Elton, 2001 .

Temperature-Sensitive Lesions in Two Influenza A Viruses Defective for Replicative Transcription Disrupt RNA Binding by the Nucleoprotein

P. Digard, D. Elton, E. Poole, 1999, Journal of Virology.

Oligomerization of the influenza virus nucleoprotein: identification of positive and negative sequence elements.

E. Medcalf, P. Digard, D. Elton, 1999, Virology.

Binding by the Nucleoprotein Replicative Transcription Disrupt RNA Influenza A Viruses Defective for Temperature-Sensitive Lesions in Two

P. Digard, D. Elton, E. Poole, 1999 .

, Elizabeth Interaction with Actin Filaments Influenza Virus Nucleoprotein through Modulation of Nuclear Localization of the

E. Medcalf, P. Digard, D. Elton, 1999 .

STING nuclear partners contribute to innate immune signaling responses

E. C. Schirmer, J. Rappsilber, G. Towers, 2021, iScience.

STING Nuclear Partners Contribute to Innate Immune Signalling Responses

E. C. Schirmer, J. Rappsilber, G. Towers, 2020, bioRxiv.

A Rab11- and Microtubule-Dependent Mechanism for Cytoplasmic Transport of Inﬂuenza A Virus Viral RNA (cid:1)

M. Amorim, P. Digard, A. Stuart, 2011 .

Specific inhibition of herpes simplex virus DNA polymerase by helical peptides corresponding to the subunit interface.

I. Brooks, D. Coen, P. Digard, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Orthomyxovirus Genome Transcription and Replication

P. Digard, D. Elton, L. Tiley, 2009 .

One for all—human kidney Caki-1 cells are highly susceptible to infection with corona- and other respiratory viruses

P. Digard, C. Hastie, A. Daniels, 2023, Journal of virology.

Role of the B Allele of Influenza A Virus Segment 8 in Setting Mammalian Host Range and Pathogenicity

S. Gygi, J. Paulo, P. Beard, 2016, Journal of Virology.

Evolutionary Conservation of the PA-X Open Reading Frame in Segment 3 of Influenza A Virus

M. Shi, E. Holmes, J. Taubenberger, 2012, Journal of virology.

Segment 2 from influenza A(H1N1) 2009 pandemic viruses confers temperature-sensitive haemagglutinin yield on candidate vaccine virus growth in eggs that can be epistatically complemented by PB2 701D.

P. Digard, O. Engelhardt, J. McCauley, 2019, The Journal of general virology.

Explorer The Rab 11 Pathway Is Required for Influenza A Virus Budding and Filament Formation

P. Digard, A. Stuart, E. Bruce, 2017 .

Evidence that the C‐terminal PB2‐binding region of the influenza A virus PB1 protein is a discrete α‐helical domain

P. Digard, D. Elton, E. Poole, 2007, FEBS letters.

Asparagine Deprivation Causes a Reversible Inhibition of Human Cytomegalovirus Acute Virus Replication

M. Auer, P. Digard, Finn E. Grey, 2019, mBio.

Zoonotic avian influenza viruses evade human BTN3A3 restriction

J. Hughes, C. Boutell, M. Palmarini, 2022, bioRxiv.

Studies of an Inﬂuenza A Virus Temperature-Sensitive Mutant Identify a Late Role for NP in the Formation of Infectious Virions (cid:1)

J. McCauley, E. Medcalf, E. Hutchinson, 2008 .

Precision cut lung slices: a novel versatile tool to examine host–pathogen interaction in the chicken lung

G. Mclachlan, P. Digard, L. Vervelde, 2020, Veterinary Research.

A quantitative proteomic analysis of lung epithelial (A549) cells infected with 2009 pandemic influenza A virus using stable isotope labelling with amino acids in cell culture

J. Barr, M. Carroll, J. Hiscox, 2012, Proteomics.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Explorer IFITM 3 restricts the morbidity and mortality associated with influenza

C. Tyler-Smith, A. Brass, D. Hume, 2016 .

The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection

Jordan J. Clark, Michael J. Murphy, Megan L. Nagel, 2023, Genome Biology.

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

Rapid selection of P323L in the SARS-CoV-2 polymerase (NSP12) in humans and non-human primate models and confers a large plaque phenotype

A. Darby, N. Randle, D. Matthews, 2021, bioRxiv.

Secreted SARS-CoV-2 ORF8 modulates the cytokine expression profile of human macrophages

J. Stewart, M. Woolhouse, P. Digard, 2021, bioRxiv.

Survival of Influenza A(H1N1) on Materials Found in Households: Implications for Infection Control

Jonathan S. Nguyen-Van-Tam, Martin D. Curran, J. Nguyen-Van-Tam, 2011, PloS one.

Erratum: An innate defense peptide BPIFA1/SPLUNC1 restricts influenza A virus infection

J. Stewart, K. Akram, A. Schorlemmer, 2018, Mucosal Immunology.

OFFICIAL JOURNAL OF THE SOCIETY FOR MUCOSAL IMMUNOLOGY, PUBLISHED BY SPRINGER NATURE

A. Schorlemmer, R. Tripp, P. Digard, 2017 .

BTN3A3 evasion promotes the zoonotic potential of influenza A viruses

J. Hughes, C. Boutell, M. Palmarini, 2023, Nature.

Comparative Analysis of Different Inbred Chicken Lines Highlights How a Hereditary Inflammatory State Affects Susceptibility to Avian Influenza Virus

P. Digard, L. Vervelde, D. Borowska, 2023, Viruses.

Explorer Comparative analysis of different inbred chicken lines highlights how a hereditary inflammatory state affects susceptibility to avian influenza virus

P. Digard, L. Vervelde, D. Borowska, 2023 .

Comparison of the efficacy of a commercial inactivated influenza A/H1N1/pdm09 virus (pH1N1) vaccine and two experimental M2e-based vaccines against pH1N1 challenge in the growing pig model

T. Opriessnig, P. Halbur, P. Gerber, 2018, PloS one.

Understanding off-target growth defects introduced to influenza A virus by synonymous recoding

P. Simmonds, P. Digard, E. Gaunt, 2023, bioRxiv.

Novel Avian Influenza Virus (H5N1) Clade 2.3.4.4b Reassortants in Migratory Birds, China

G. Gao, Y. Bi, X. Hao, 2023, Emerging infectious diseases.

Novel technology to develop non-transmissible live influenza virus vaccines through alterations in M2/M42 ion channel expression

D. Suarez, P. Digard, L. Vervelde, 2023, bioRxiv.

Explorer Modelling the structure and dynamics of biological pathways

Lee B. Smith, T. Freeman, P. Digard, 2016 .

Explorer Modelling the structure and dynamics of biological pathways

Lee B. Smith, P. Digard, Benjamin Boyer, 2016 .

Modelling the structure and dynamics of biological pathways

Lee B. Smith, T. Freeman, P. Digard, 2016 .

Explorer Modelling the structure and dynamics of biological pathways

Lee B. Smith, P. Digard, Benjamin Boyer, 2016 .

Blood-based epigenome-wide analyses of nineteen common disease states :

P. Digard, L. Vervelde, D. Borowska, 2023 .

A comparative analysis of host responses to avian influenza infection in ducks and chickens highlights a role for the interferon-induced transmembrane proteins in viral resistance

D. Burt, R. Webster, Jacqueline Smith, 2015, BMC Genomics.

Comparison of the efficacy of a commercial inactivated influenza A/H1N1/pdm09 virus (pH1N1) vaccine and two experimental M2e-based vaccines against pH1N1 challenge in the growing pig model

T. Opriessnig, P. Halbur, P. Gerber, 2018, PloS one.

Identification of amino acid residues of influenza virus nucleoprotein essential for RNA binding

P. Digard, D. Elton, L. Medcalf, 1999 .

Edinburgh Research Explorer Identification of amino acid residues of influenza virus nucleoprotein essential for RNA binding

P. Digard, D. Elton, L. Medcalf, 1999 .

Polymerization activity of an alpha-like DNA polymerase requires a conserved 3'-5' exonuclease active site

D. Knipe, P. Digard, Anne, 2016 .

A novel functional domain of an alpha-like DNA polymerase. The binding site on the herpes simplex virus polymerase for the viral UL42 protein.

D. Coen, P. Digard, 1990, The Journal of biological chemistry.

Characterisation of Influenza a Viruses with Mutations in Segment 5 Packaging Signals Characterisation of Influenza a Viruses with Mutations in Segment 5 Packaging Signals

E. Hutchinson, P. Digard, H. Wise, 2022 .

Interaction of the Influenza Virus Nucleoprotein with the Cellular CRM1-Mediated Nuclear Export Pathway

P. Digard, D. Elton, L. Medcalf, 2001, Journal of Virology.

The Rab11 Pathway Is Required for Influenza A Virus Budding and Filament Formation

P. Digard, A. Stuart, E. Bruce, 2010, Journal of Virology.

The environmental deposition of influenza virus from patients infected with influenza A(H1N1)pdm09: Implications for infection prevention and control.

W. Lim, S. Cauchemez, J. Nguyen-Van-Tam, 2016, Journal of infection and public health.

Quantitative proteomics using SILAC coupled to LC-MS/MS reveals changes in the nucleolar proteome in influenza A virus-infected cells.

D. Matthews, J. Hiscox, P. Digard, 2010, Journal of proteome research.

IFITM3 restricts the morbidity and mortality associated with influenza

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