J. Ambroso

发表

Chloroquine accumulation and alterations of proteolysis and pinocytosis in the rat conceptus in vitro.

C. Harris, J. Ambroso, 1994, Biochemical pharmacology.

Assessment of thyroid modulating activity and its application in preclinical drug development Methods and mechanisms

R. T. Miller, J. Ambroso, J. Giridhar, 2003 .

In vitro embryotoxicity of the cysteine proteinase inhibitors benzyloxycarbonyl-phenylalanine-alanine-diazomethane (Z-Phe-Ala-CHN2) and benzyloxycarbonyl-phenylalanine-phenylalanine-diazomethane (Z-Phe-Phe-CHN2).

C. Harris, J. Ambroso, 1994, Teratology.

Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes.

M. J. Bishop, J. Ambroso, J. Collins, 2013, Journal of medicinal chemistry.

Chloroquine embryotoxicity in the postimplantation rat conceptus in vitro.

C. Harris, J. Ambroso, Craig Harris, 1993, Teratology.

Characterization of cell death induced by 2-methoxyethanol in CD-1 mouse embryos on gestation day 8.

J. Ambroso, B. Elswick, F. Welsch, 1998, Teratology.

Inhibition of neurotoxic esterase in vitro by novel carbamates.

J. Ambroso, R. Richardson, W. Groutas, 1997, Toxicology and applied pharmacology.

Mechanistic Modeling Reveals the Critical Knowledge Gaps in Bile Acid–Mediated DILI

P. Watkins, K. Brouwer, S. Siler, 2014, CPT: pharmacometrics & systems pharmacology.

Effects of mid-respiratory chain inhibition on mitochondrial function in vitro and in vivo

T. Gant, A. Boobis, J. Ambroso, 2015, Toxicology research.

Fluorometric analysis of endocytosis and lysosomal proteolysis in the rat visceral yolk sac during whole embryo culture.

C. Harris, J. Ambroso, R. K. Brabec, 1997, Teratology.

Biological Interactions between Nanomaterials and Placental Development and Function Following Oral Exposure.

T. Fennell, K. Grieger, J. Ambroso, 2019, Reproductive toxicology.

Two-generation reproduction studies in Rats fed di-isodecyl phthalate.

J. J. Freeman, R. H. Mckee, J. Ambroso, 2001, Reproductive toxicology.

Developmental toxicity of di-isodecyl and di-isononyl phthalates in rats.

J. Ambroso, S. Harris, G. Trimmer, 1999, Reproductive toxicology.

Lymphocyte loss and immunosuppression following acetaminophen-induced hepatotoxicity in mice as a potential mechanism of tolerance.

J. Ambroso, L. Pohl, M. L. Graf, 2007, Chemical research in toxicology.

Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.

J. Ambroso, H. Ellens, M. Reese, 2012, Chemical research in toxicology.

Assessment of histiotrophic nutrition using fluorescent probes.

C. Harris, J. Ambroso, 2012, Methods in molecular biology.

An integrated reactive metabolite evaluation approach to assess and reduce safety risk during drug discovery and development.

Jeffrey Ambroso, Eric Yang, J. Ambroso, 2011, Chemico-biological interactions.

Assessment of the Carcinogenic Potential of Pretomanid in Transgenic Tg.rasH2 Mice

J. Ambroso, Tian Yang, J. Dillberger, 2022, International journal of toxicology.

Toxicity and toxicokinetic assessment of an anti-tubercular drug pretomanid in cynomolgus monkeys

J. Ambroso, Tian J. Yang, J. Dillberger, 2022, Toxicology Reports.

Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes.

M. J. Bishop, J. Ambroso, J. Collins, 2013, Journal of medicinal chemistry.