S. Dujardin

发表

Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer’s Disease

Sean J. Miller, J. Mertens, L. Petrucelli, 2018, Neuron.

Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo

I. Nelken, B. Hyman, G. Carlson, 2018, Nature Neuroscience.

Lentiviral delivery of the human wild-type tau protein mediates a slow and progressive neurodegenerative tau pathology in the rat brain.

J. Winderickx, L. Buée, V. Deramecourt, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

LRP1 and SORL1 regulate tau internalization and degradation and enhance tau seeding

B. Hyman, D. Strickland, Joanna M. Cooper, 2020, bioRxiv.

Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer’s Disease

Christoph N Schlaffner, Amanda J. Guise, Christoph N. Schlaffner, 2020, Cell.

Novel genetic variants in MAPT and alterations in tau phosphorylation in amyotrophic lateral sclerosis post‐mortem motor cortex and cerebrospinal fluid

Derek H. Oakley, B. Hyman, S. Arnold, 2021, Brain pathology.

Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons

Derek H. Oakley, B. Hyman, M. Frosch, 2021, The Journal of Neuroscience.

Impact of Sterilization Methods on the Seeding Ability of Human Tau Proteopathic Seeds.

B. Hyman, M. Frosch, S. Dujardin, 2021, Journal of neuropathology and experimental neurology.

Clinical, neuropathological, and biochemical characterization of the novel tau mutation P332S.

F. Pasquier, L. Buée, F. Lebert, 2012, Journal of Alzheimer's disease : JAD.

Targeting Tau Mitigates Mitochondrial Fragmentation and Oxidative Stress in Amyotrophic Lateral Sclerosis

Derek H. Oakley, S. Haggarty, B. Hyman, 2021, Molecular Neurobiology.

Selection of an Efficient AAV Vector for Robust CNS Transgene Expression

E. Hudry, M. Sena-Esteves, S. Dujardin, 2019, Molecular therapy. Methods & clinical development.

Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer’s Disease

Sean J. Miller, F. Gage, J. Mertens, 2019, Neuron.

Targeting Tau Mitigates Mitochondrial Fragmentation and Oxidative Stress in Amyotrophic Lateral Sclerosis

Derek H. Oakley, S. Haggarty, B. Hyman, 2021, Molecular Neurobiology.

Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease

Derek H. Oakley, B. Hyman, J. Steen, 2020, Nature Medicine.

Tau Prion-Like Propagation: State of the Art and Current Challenges.

B. Hyman, S. Dujardin, 2019, Advances in experimental medicine and biology.

Tau reduction in the presence of amyloid-&bgr; prevents tau pathology and neuronal death in vivo

Daniel Irimia, Matthew P Frosch, Mehdi Jorfi, 2018, Brain : a journal of neurology.

Enhanced Tau Aggregation in the Presence of Amyloid β.

Matthew P Frosch, B. Hyman, M. Frosch, 2017, The American journal of pathology.

Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies

M. Colin, S. Dujardin, M. Tardivel, 2016, Acta neuropathologica communications.

In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy

K. Nilsson, B. Bacskai, Steven S. Hou, 2019, Acta Neuropathologica Communications.

Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies

J. Winderickx, L. Buée, N. Déglon, 2014, Acta neuropathologica communications.

Rate of tau propagation is a heritable disease trait in genetically diverse mouse strains

B. Hyman, L. Chibnik, C. Kaczorowski, 2023, iScience.

Tau propagation is dependent on the genetic background of mouse strains

B. Hyman, S. Dujardin, Riley N. Bannon, 2022, Brain communications.

Erratum: Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease (Neuron (2018) 99(5) (925–940.e7), (S0896627318306378) (10.1016/j.neuron.2018.07.039))

Sean J. Miller, F. Gage, J. Mertens, 2019 .

Tau protein liquid–liquid phase separation can initiate tau aggregation

Daniel J. Muller, Anthony A Hyman, A. Hyman, 2018, The EMBO journal.

From the prion-like propagation hypothesis to therapeutic strategies of anti-tau immunotherapy

L. Buée, C. Duyckaerts, M. Colin, 2019, Acta Neuropathologica.

What is the evidence that tau pathology spreads through prion-like propagation?

Luc Buée, Michel Goedert, L. Buée, 2017, Acta neuropathologica communications.

Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo

I. Nelken, B. Hyman, G. Carlson, 2018, Nature Neuroscience.

De la cellule au primate, propagation physiopathologique de la protéine Tau

S. Dujardin, 2015 .

Invited review: Animal models of tauopathies and their implications for research/translation into the clinic

L. Buée, M. Colin, S. Dujardin, 2015, Neuropathology and applied neurobiology.

A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer’s disease

K. Blennow, B. Hyman, B. de Strooper, 2020, Acta Neuropathologica.

Different tau species lead to heterogeneous tau pathology propagation and misfolding

B. Hyman, L. Buée, M. Frosch, 2018, Acta neuropathologica communications.

Ectosomes: A New Mechanism for Non-Exosomal Secretion of Tau Protein

L. Buée, M. Colin, A. Loyens, 2014, PloS one.

Regulation of tau internalization, degradation, and seeding by LRP1 reveals multiple pathways for tau catabolism

B. Hyman, D. Strickland, Joanna M. Cooper, 2021, The Journal of biological chemistry.

Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies

L. Buée, M. Colin, S. Dujardin, 2016, Acta neuropathologica communications.

Kinetics of tau aggregation reveals patient-specific tau characteristics among Alzheimer’s cases

Derek H. Oakley, B. Hyman, M. Frosch, 2021, Brain communications.

Tau reduction in aged mice does not impact Microangiopathy

B. Hyman, S. Dujardin, Rachel E. Bennett, 2020, Acta Neuropathologica Communications.

In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy

K. Nilsson, B. Bacskai, Steven S. Hou, 2019, Acta Neuropathologica Communications.

Tau reduction in aged mice does not impact Microangiopathy

B. Hyman, S. Dujardin, Rachel E. Bennett, 2020, Acta Neuropathologica Communications.

An in-depth analysis of phosphorylated tau in amyotrophic lateral sclerosispost-mortem motor cortex and cerebrospinal fluid

B. Hyman, S. Arnold, T. Gómez-Isla, 2021, medRxiv.

Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds

B. Hyman, S. Dujardin, Rachel E. Bennett, 2020, Acta neuropathologica communications.

Tau Protein Disrupts Nucl eocytoplasmic Transport in Alzheimer ’ s Disease Graphical Abstract Highlights

Sean J. Miller, C. R. Vanderburgh, F. Gage, 2018 .

Different tau species lead to heterogeneous tau pathology propagation and misfolding

B. Hyman, L. Buée, M. Frosch, 2018, Acta Neuropathologica Communications.

Lentiviral delivery of the human wild-type tau protein mediates a slow and progressive neurodegenerative tau pathology in the rat brain.

J. Winderickx, L. Buée, V. Deramecourt, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.