K. Nguyen

发表

The CRM1 nuclear export protein in normal development and disease.

M. P. Holloway, R. Altura, K. Nguyen, 2012, International journal of biochemistry and molecular biology.

An asymptomatic mutation complicating severe chemotherapy-induced peripheral neuropathy (CIPN): a case for personalised medicine and a zebrafish model of CIPN

M. P. Holloway, R. Altura, C. Jackson, 2016, npj Genomic Medicine.

Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor.

M. Rudd, P. Coleman, S. Harper, 2012, ACS medicinal chemistry letters.

Discovery of vaniprevir (MK-7009), a macrocyclic hepatitis C virus NS3/4a protease inhibitor.

M. Rudd, D. Graham, M. Holloway, 2010, Journal of medicinal chemistry.

Discovery of MK-1220: A Macrocyclic Inhibitor of Hepatitis C Virus NS3/4A Protease with Improved Preclinical Plasma Exposure.

M. Rudd, D. Graham, M. Holloway, 2011, ACS medicinal chemistry letters.

Bismacrocyclic inhibitors of hepatitis C NS3/4a protease.

M. Rudd, J. Vacca, N. Liverton, 2008, Angewandte Chemie.

Development of potent macrocyclic inhibitors of genotype 3a HCV NS3/4A protease.

Qian Huang, Adam T. Gates, M. Rudd, 2012, Bioorganic & medicinal chemistry letters.

P2‐Quinazolinones and Bis‐Macrocycles as New Templates for Next‐Generation Hepatitis C Virus NS3/4a Protease Inhibitors: Discovery of MK‐2748 and MK‐6325

Qian Huang, Adam T. Gates, M. Rudd, 2015, ChemMedChem.

An efficient synthesis of tetrasubstituted imidazoles from N-(2-Oxo)-amides

N. Liverton, C. Claiborne, K. Nguyen, 1998 .

Molecular modeling based approach to potent P2-P4 macrocyclic inhibitors of hepatitis C NS3/4A protease.

M. Katharine Holloway, M. Rudd, M. Holloway, 2008, Journal of the American Chemical Society.

Identification and characterization of 4-methylbenzyl 4-[(pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate, an orally bioavailable, brain penetrant NR2B selective N-methyl-D-aspartate receptor antagonist.

A. Dilella, N. Liverton, C. Claiborne, 2007, Journal of medicinal chemistry.

NITROGEN BRIDGE HOMOEPIBATIDINES. SYN-6- AND SYN-5(6-CHLORO-3-PYRIDYL)ISOQUINUCLIDINES

K. Nguyen, P. Carroll, F. Zuo, 1999 .

Cyclic benzamidines as orally efficacious NR2B-selective NMDA receptor antagonists.

N. Liverton, C. Claiborne, K. Nguyen, 2007, Bioorganic & medicinal chemistry letters.

Quantitative Phosphoproteomic Analysis Identifies Activation of the RET and IGF-1R/IR Signaling Pathways in Neuroblastoma

M. P. Holloway, R. Altura, M. Valentine, 2013, PloS one.

Review Article The CRM1 nuclear export protein in normal development and disease

M. P. Holloway, R. Altura, K. Nguyen, 2012 .

The CRM 1 nuclear export protein in normal development and disease

M. P. Holloway, R. Altura, K. Nguyen, 2012 .

CD44 Regulates Pancreatic Cancer Invasion through MT1-MMP

K. Nguyen, M. P. di Magliano, Wei Jiang, 2015, Molecular Cancer Research.

The Role of Phosphatidylinositol 3-Kinase, Rho Family GTPases, and STAT3 in Ros-induced Cell Transformation*

Maithao Le, C. S. Zong, K. Nguyen, 2002, The Journal of Biological Chemistry.

Differential requirements of the MAP kinase and PI3 kinase signaling pathways in Src- versus insulin and IGF-1 receptors-induced growth and transformation of rat intestinal epithelial cells

K. Nguyen, J. Chan, Lu‐Hai Wang, 2000, Oncogene.

Synergistic effect between EGF and TGF-β1 in inducing oncogenic properties of intestinal epithelial cells

K. Nguyen, S. Uttamsingh, J. Chan, 2008, Oncogene.

Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase.

E. A. O'neill, J. Vacca, B. Frantz, 1999, Journal of medicinal chemistry.

Discovery of vaniprevir (MK-7009), a macrocyclic hepatitis C virus NS3/4a protease inhibitor.

M. Rudd, D. Graham, J. Vacca, 2010, Journal of medicinal chemistry.

Discovery of MK-1220: A Macrocyclic Inhibitor of Hepatitis C Virus NS3/4A Protease with Improved Preclinical Plasma Exposure.

M. Rudd, D. Graham, J. Vacca, 2011, ACS medicinal chemistry letters.