J. Partridge

发表

The nuclear pore complex has entered the atomic age.

J. Whittle, T. Schwartz, S. Brohawn, 2009, Structure.

The nuclear pore complex has entered the atomic age Citation Brohawn

J. Whittle, S. Brohawn, J. Partridge, 2009 .

The stoichiometry of the nucleoporin 62 subcomplex of the nuclear pore in solution

T. Schwartz, J. Partridge, Alexander Ulrich, 2014, Molecular biology of the cell.

Crystallographic and biochemical analysis of the Ran-binding zinc finger domain.

T. Schwartz, J. Partridge, 2009, Journal of molecular biology.

Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin

C. Johnson, S. Almo, Lan Hua, 2017, ACS medicinal chemistry letters.

Structures of full-length plasma kallikrein bound to highly specific inhibitors describe a new mode of targeted inhibition.

H. Sham, J. Partridge, B. Metcalf, 2019, Journal of structural biology.

Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism.

D. Elnatan, D. Agard, Laura A Lavery, 2014, Molecular cell.

Structure-Guided Design of Novel, Potent, and Selective Macrocyclic Plasma Kallikrein Inhibitors.

H. Sham, J. Partridge, Yunjin Hu, 2017, ACS medicinal chemistry letters.

Structures of human plasma β-factor XIIa cocrystallized with potent inhibitors.

H. Sham, J. Partridge, A. Dementiev, 2018, Blood advances.

A Structural Element within the HUWE1 HECT Domain Modulates Self-ubiquitination and Substrate Ubiquitination Activities*

H. Ploegh, T. Schwartz, J. Partridge, 2009, The Journal of Biological Chemistry.

A novel N-terminal extension in mitochondrial TRAP1 serves as a thermal regulator of chaperone activity

D. Elnatan, D. Agard, Laura A Lavery, 2014, eLife.

A small molecule that preferentially binds the closed conformation of Hsp90.

D. Agard, J. Partridge, S. McAlpine, 2011, Bioorganic & medicinal chemistry letters.

The nuclear pore complex has entered the atomic age.

J. Whittle, T. Schwartz, S. Brohawn, 2009, Structure.

GBT021601 improves red blood cell health and the pathophysiology of sickle cell disease in a murine model

Alexander T. Williams, Steven C. Strutt, C. Muller, 2023, British journal of haematology.

A small molecule that preferentially binds the closed conformation of Hsp90.

D. Agard, J. Partridge, S. McAlpine, 2011, Bioorganic & medicinal chemistry letters.