Á. Martínez-del-Pozo

发表

Evaluation of different approaches used to study membrane permeabilization by actinoporins on model lipid vesicles.

J. Slotte, J. Gavilanes, Juan Palacios-Ortega, 2020, Biochimica et biophysica acta. Biomembranes.

Functional and Structural Variation among Sticholysins, Pore-Forming Proteins from the Sea Anemone Stichodactyla helianthus

J. Slotte, J. Gavilanes, Juan Palacios-Ortega, 2020, International journal of molecular sciences.

Ribotoxins ribonucleolytic activity is not essential for in vitro protein biosynthesis inhibition

N. Olmo, J. Gavilanes, E. Herrero-Galán, 2011 .

Regulation of Sticholysin II-Induced Pore Formation by Lipid Bilayer Composition, Phase State, and Interfacial Properties.

J. Slotte, J. Gavilanes, Juan Palacios-Ortega, 2016, Langmuir : the ACS journal of surfaces and colloids.

Toxin-induced pore formation is hindered by intermolecular hydrogen bonding in sphingomyelin bilayers.

J. Slotte, J. Gavilanes, Juan Palacios-Ortega, 2016, Biochimica et biophysica acta.

Production of the biotechnologically relevant AFP from Aspergillus giganteus in the yeast Pichia pastoris.

J. Gavilanes, Á. Martínez-del-Pozo, B. San Segundo, 2010, Protein expression and purification.

Fungal extracellular ribotoxins as insecticidal agents.

J. Gavilanes, E. Herrero-Galán, Á. Martínez-del-Pozo, 2013, Insect biochemistry and molecular biology.

Sticholysin I–II oligomerization in the absence of membranes

J. Gavilanes, Juan Palacios-Ortega, Á. Martínez-del-Pozo, 2022, FEBS letters.

Production and characterization of scFvA33T1, an immunoRNase targeting colon cancer cells

C. Batt, J. Gavilanes, Á. Martínez-del-Pozo, 2012, The FEBS journal.

Production and characterization of a colon cancer-specific immunotoxin based on the fungal ribotoxin α-sarcin.

C. Batt, J. Gavilanes, Á. Martínez-del-Pozo, 2012, Protein engineering, design & selection : PEDS.

Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin α-sarcin in nude mice bearing human colorectal cancer xenografts

J. Gavilanes, Á. Martínez-del-Pozo, Miriam Olombrada, 2015, SpringerPlus.

α‐sarcin and RNase T1 based immunoconjugates: the role of intracellular trafficking in cytotoxic efficiency

J. Gavilanes, Á. Martínez-del-Pozo, J. Tomé-Amat, 2015, The FEBS journal.

Preparation of an engineered safer immunotoxin against colon carcinoma based on the ribotoxin hirsutellin A

J. Gavilanes, E. Herrero-Galán, Á. Martínez-del-Pozo, 2015, The FEBS journal.

Na+ controls hypoxic signalling by the mitochondrial respiratory chain

L. Moreno, P. Navas, J. Enríquez, 2020, Nature.

Synergistic Action of Actinoporin Isoforms from the Same Sea Anemone Species Assembled into Functionally Active Heteropores*

J. Gavilanes, J. Alegre-Cebollada, Esperanza Rivera-de-Torre, 2016, The Journal of Biological Chemistry.

Sea Anemones, Actinoporins, and Cholesterol

J. Gavilanes, Juan Palacios-Ortega, Á. Martínez-del-Pozo, 2022, International journal of molecular sciences.

1H, 13C, and 15N NMR assignments of StnII-Y111N, a highly impaired mutant of the sea anemone actinoporin Sticholysin II

J. Gavilanes, J. Alegre-Cebollada, Á. Martínez-del-Pozo, 2010, Biomolecular NMR assignments.

Mitochondrial Na+ controls oxidative phosphorylation and hypoxic redox signalling

L. Moreno, P. Navas, J. Ruíz-Cabello, 2018, bioRxiv.

Sticholysin, Sphingomyelin, and Cholesterol: A Closer Look at a Tripartite Interaction.

J. Slotte, J. Gavilanes, Juan Palacios-Ortega, 2019, Biophysical journal.

Cholesterol stimulates and ceramide inhibits Sticholysin II-induced pore formation in complex bilayer membranes.

J. Slotte, J. Gavilanes, Á. Martínez-del-Pozo, 2015, Biochimica et biophysica acta.

Der p 1-based immunotoxin as potential tool for the treatment of dust mite respiratory allergy

S. Benedé, Á. Martínez-del-Pozo, C. Mayorga, 2020, Scientific Reports.

A deletion variant of the Aspergillus fumigatus ribotoxin Asp f 1 induces an attenuated airway inflammatory response in a mouse model of sensitization.

J. Gavilanes, Á. Martínez-del-Pozo, E. Batanero, 2010, Journal of investigational allergology & clinical immunology.

Determination of the boundary lipids of sticholysins using tryptophan quenching

J. Slotte, Juan Palacios-Ortega, Á. Martínez-del-Pozo, 2022, Scientific Reports.

The therapeutic potential of fungal ribotoxins.

J. Gavilanes, E. Herrero-Galán, J. Alegre-Cebollada, 2008, Current pharmaceutical biotechnology.

A PR-1-like Protein of Fusarium oxysporum Functions in Virulence on Mammalian Hosts*

J. Guarro, A. Di Pietro, Á. Martínez-del-Pozo, 2012, The Journal of Biological Chemistry.

Characterization of a novel cysteine-rich antifungal protein from Fusarium graminearum with activity against maize fungal pathogens.

A. Di Pietro, Á. Martínez-del-Pozo, M. Roncero, 2018, International journal of food microbiology.

Minimized natural versions of fungal ribotoxins show improved active site plasticity.

J. Gavilanes, Á. Martínez-del-Pozo, Miriam Olombrada, 2017, Archives of biochemistry and biophysics.

Differential Effect of Membrane Composition on the Pore-Forming Ability of Four Different Sea Anemone Actinoporins.

J. Slotte, J. Gavilanes, K. Tsumoto, 2016, Biochemistry.

Role of the Tryptophan Residues in the Specific Interaction of the Sea Anemone Stichodactyla helianthus's Actinoporin Sticholysin II with Biological Membranes.

J. Slotte, J. Gavilanes, Esperanza Rivera-de-Torre, 2016, Biochemistry.

Differential toxicity of antifungal protein AFP against mutants of Fusarium oxysporum.

A. Di Pietro, Á. Martínez-del-Pozo, M. Roncero, 2009, International microbiology : the official journal of the Spanish Society for Microbiology.

A novel Carcinoembryonic Antigen (CEA)-Targeted Trimeric Immunotoxin shows significantly enhanced Antitumor Activity in Human Colorectal Cancer Xenografts

J. Gavilanes, L. Álvarez-Vallina, Á. Martínez-del-Pozo, 2019, Scientific Reports.

The ribotoxin α-sarcin can cleave the sarcin/ricin loop on late 60S pre-ribosomes

V. G. Panse, J. Gavilanes, Á. Martínez-del-Pozo, 2020, Nucleic acids research.

Fungal Ribotoxins: A Review of Potential Biotechnological Applications

J. Gavilanes, Á. Martínez-del-Pozo, Miriam Olombrada, 2017, Toxins.

Involvement of loops 2 and 3 of α-sarcin on its ribotoxic activity.

J. Gavilanes, Á. Martínez-del-Pozo, C. Castaño-Rodríguez, 2015, Toxicon : official journal of the International Society on Toxinology.

The acidic ribosomal stalk proteins are not required for the highly specific inactivation exerted by α-sarcin of the eukaryotic ribosome.

J. Ballesta, M. Remacha, J. Gavilanes, 2014, Biochemistry.

Involvement of loop 5 lysine residues and the N-terminal β-hairpin of the ribotoxin hirsutellin A on its insecticidal activity

J. Gavilanes, Á. Martínez-del-Pozo, Miriam Olombrada, 2016, Biological chemistry.

Fungal ribotoxins: Natural protein-based weapons against insects.

J. Gavilanes, Á. Martínez-del-Pozo, Miriam Olombrada, 2014, Toxicon : official journal of the International Society on Toxinology.

A non-cytotoxic but ribonucleolytically specific ribotoxin variant: implication of tryptophan residues in the cytotoxicity of hirsutellin A

N. Olmo, J. Gavilanes, E. Herrero-Galán, 2012, Biological chemistry.

The ribonucleolytic activity of the ribotoxin α-sarcin is not essential for in vitro protein biosynthesis inhibition.

N. Olmo, J. Gavilanes, E. Herrero-Galán, 2011, Biochimica et biophysica acta.

Role of the basic character of alpha-sarcin's NH2-terminal beta-hairpin in ribosome recognition and phospholipid interaction.

J. Gavilanes, Á. Martínez-del-Pozo, E. Álvarez-García, 2009, Archives of biochemistry and biophysics.

Influence of key residues on the heterologous extracellular production of fungal ribonuclease U2 in the yeast Pichia pastoris.

J. Gavilanes, Á. Martínez-del-Pozo, V. de los Ríos, 2009, Protein expression and purification.

One single salt bridge explains the different cytolytic activities shown by actinoporins sticholysin I and II from the venom of Stichodactyla helianthus.

J. Gavilanes, Juan Palacios-Ortega, Esperanza Rivera-de-Torre, 2017, Archives of biochemistry and biophysics.

Calorimetric scrutiny of lipid binding by sticholysin II toxin mutants.

J. Gavilanes, E. Herrero-Galán, J. Alegre-Cebollada, 2008, Journal of molecular biology.

Implication of an Asp residue in the ribonucleolytic activity of hirsutellin A reveals new electrostatic interactions at the active site of ribotoxins.

N. Olmo, J. Gavilanes, E. Herrero-Galán, 2012, Biochimie.

The behavior of sea anemone actinoporins at the water-membrane interface.

J. Gavilanes, J. Alegre-Cebollada, Á. Martínez-del-Pozo, 2011, Biochimica et biophysica acta.

Pore-Forming Proteins from Cnidarians and Arachnids as Potential Biotechnological Tools

J. Gavilanes, Juan Palacios-Ortega, Esperanza Rivera-de-Torre, 2019, Toxins.

Structure of Fungal α Mating Pheromone in Membrane Mimetics Suggests a Possible Role for Regulation at the Water-Membrane Interface

David Turrà, A. Di Pietro, Á. Martínez-del-Pozo, 2020, Frontiers in Microbiology.

The Metamorphic Transformation of a Water-Soluble Monomeric Protein Into an Oligomeric Transmembrane Pore

J. Gavilanes, Juan Palacios-Ortega, Esperanza Rivera-de-Torre, 2017 .

Cleavage of the sarcin–ricin loop of 23S rRNA differentially affects EF-G and EF-Tu binding

S. Joseph, J. Gavilanes, Á. Martínez-del-Pozo, 2010, Nucleic acids research.

The sea anemone actinoporin (Arg‐Gly‐Asp) conserved motif is involved in maintaining the competent oligomerization state of these pore‐forming toxins

J. Gavilanes, Á. Martínez-del-Pozo, Sara García-Linares, 2014, The FEBS journal.

Specific interactions of sticholysin I with model membranes: An NMR study

J. Gavilanes, J. Alegre-Cebollada, Á. Martínez-del-Pozo, 2010, Proteins.

Structural and functional characterization of sticholysin III: A newly discovered actinoporin within the venom of the sea anemone Stichodactyla helianthus.

J. Slotte, J. Gavilanes, Juan Palacios-Ortega, 2020, Archives of biochemistry and biophysics.

The Effect of Cholesterol on the Long-Range Network of Interactions Established among Sea Anemone Sticholysin II Residues at the Water-Membrane Interface

J. Slotte, J. Gavilanes, Á. Martínez-del-Pozo, 2015, Marine Drugs.

Three-dimensional structure of the actinoporin sticholysin I. Influence of long-distance effects on protein function.

J. Gavilanes, J. Alegre-Cebollada, M. Menéndez, 2013, Archives of biochemistry and biophysics.

Structure-Activity Relationship of α Mating Pheromone from the Fungal Pathogen Fusarium oxysporum*

David Turrà, A. Di Pietro, Á. Martínez-del-Pozo, 2017, The Journal of Biological Chemistry.

Characterization of a new toxin from the entomopathogenic fungus Metarhizium anisopliae: the ribotoxin anisoplin

J. Gavilanes, Á. Martínez-del-Pozo, Miriam Olombrada, 2017, Biological chemistry.

Biophysical approaches to study actinoporin-lipid interactions.

J. Slotte, J. Gavilanes, Juan Palacios-Ortega, 2021, Methods in enzymology.

Stichodactyla helianthus' de novo transcriptome assembly: Discovery of a new actinoporin isoform

Esperanza Rivera-de-Torre, Á. Martínez-del-Pozo, Jessica E. Garb, 2018, Toxicon : official journal of the International Society on Toxinology.

Sticholysin recognition of ceramide-phosphoethanolamine.

Juan Palacios-Ortega, Á. Martínez-del-Pozo, Sara García-Linares, 2023, Archives of Biochemistry and Biophysics.

Differential Effect of Bilayer Thickness on Sticholysin Activity.

J. Slotte, J. Gavilanes, Juan Palacios-Ortega, 2017, Langmuir : the ACS journal of surfaces and colloids.

2NH and 3OH are crucial structural requirements in sphingomyelin for sticholysin II binding and pore formation in bilayer membranes.

Sanna P. Niinivehmas, J. Gavilanes, S. Katsumura, 2013, Biochimica et biophysica acta.

Structural foundations of sticholysin functionality.

J. Slotte, J. Gavilanes, Juan Palacios-Ortega, 2021, Biochimica et biophysica acta. Proteins and proteomics.

Oligomerization of Sticholysins from Förster Resonance Energy Transfer

J. Slotte, J. Gavilanes, Juan Palacios-Ortega, 2021, Biochemistry.

Intrinsic local disorder and a network of charge–charge interactions are key to actinoporin membrane disruption and cytotoxicity

J. Gavilanes, J. Alegre-Cebollada, Á. Martínez-del-Pozo, 2011, The FEBS journal.

Cell response to extracellular matrix energy dissipation outweighs rigidity sensing

G. Plaza, Pere Roca-Cusachs, L. Gutierrez-Rus, 2022, bioRxiv.