C. Shanahan

C. Shanahan, 2006, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

The circulating calcification inhibitors, fetuin-A and osteoprotegerin, but not matrix Gla protein, are associated with vascular stiffness and calcification in children on dialysis.

L. Hofbauer, L. Schurgers, J. Deanfield, 2008, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Vascular calcification: new insights into an old problem

P. Weissberg, C. Shanahan, D. Proudfoot, 1998, The Journal of pathology.

Calcinosis: insights from other calcinoses

C. Shanahan, S. S. Tsakali, 2020, Current opinion in rheumatology.

Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques

A. Didangelos, M. Mayr, A. Davies, 2017, The Journal of clinical investigation.

Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization

J. Skepper, Steven F. Lee, H. Oschkinat, 2019, Cell reports.

Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization

J. Skepper, Steven F. Lee, H. Oschkinat, 2019, Cell reports.

Mineral Surface in Calcified Plaque Is Like That of Bone: Further Evidence for Regulated Mineralization

J. Skepper, T. Friščić, C. Shanahan, 2008, Arteriosclerosis, thrombosis, and vascular biology.

Targeting vascular calcification: softening-up a hard target.

C. Shanahan, A. Kapustin, 2009, Current opinion in pharmacology.

R. Hayward, C. Shanahan, A. Cobb, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Molecular cloning of cDNA encoding the 110 kDa and 21 kDa regulatory subunits of smooth muscle protein phosphatase 1M

Philip R. Cohen, D. Alessi, D. Campbell, 1994, FEBS letters.

Mouse models of nesprin-related diseases.

C. Shanahan, D. Warren, L. Rao, 2018, Biochemical Society transactions.

Endoplasmic Reticulum Stress Mediates Vascular Smooth Muscle Cell Calcification via Increased Release of Grp78 (Glucose-Regulated Protein, 78 kDa)-Loaded Extracellular Vesicles

L. Schurgers, C. Shanahan, A. Kapustin, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Neuropathy and the vascular-bone axis in diabetes: lessons from Charcot osteoarthropathy

C. Shanahan, N. Petrova, 2014, Osteoporosis International.

In situ characterization of advanced glycation end products (AGEs) in collagen and model extracellular matrix by solid state NMR† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7cc06624d

R. Li, R. Hayward, C. Shanahan, 2017, Chemical communications.

Nanocrystals seed calcification in more ways than one.

C. Shanahan, D. Proudfoot, 2011, Kidney international.

Multifunctional roles for serum protein fetuin-a in inhibition of human vascular smooth muscle cell calcification.

J. Skepper, P. Weissberg, W. Jahnen-Dechent, 2005, Journal of the American Society of Nephrology : JASN.

Osteocalcin: a novel vascular metabolic and osteoinductive factor?

C. Shanahan, A. Kapustin, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Heterogeneity of gene expression in human atheroma unmasked using cDNA representational difference analysis.

P. Weissberg, C. Shanahan, K. Tyson, 2002, Physiological genomics.

Use of cDNA representational difference analysis to identify disease-specific genes in human atherosclerotic plaques.

C. Shanahan, K. Tyson, K. Tyson, 1999, Methods in molecular medicine.

The effect of particle agglomeration on the formation of a surface-connected compartment induced by hydroxyapatite nanoparticles in human monocyte-derived macrophages☆

J. Skepper, A. Routh, C. Shanahan, 2014, Biomaterials.

Human vascular smooth muscle cell culture.

C. Shanahan, D. Proudfoot, 2012, Methods in molecular biology.

Dialysis Accelerates Medial Vascular Calcification in Part by Triggering Smooth Muscle Cell Apoptosis

L. Schurgers, J. Skepper, N. Figg, 2008, Circulation.

Klotho: an elixir of youth for the vasculature?

C. Shanahan, R. Shroff, 2011, Journal of the American Society of Nephrology : JASN.

Exploring the biology of vascular calcification in chronic kidney disease: what's circulating?

L. Hofbauer, C. Shanahan, M. Schoppet, 2008, Kidney international.

Biology of Calcification in Vascular Cells: Intima versus Media

C. Shanahan, D. Proudfoot, 2001, Herz.

A potential role for sterol 27-hydroxylase in atherogenesis.

C. Shanahan, N. Cary, K. Carpenter, 2001, Atherosclerosis.

Calcium Regulates Key Components of Vascular Smooth Muscle Cell–Derived Matrix Vesicles to Enhance Mineralization

M. Mayr, Gregory T. Jones, L. Schurgers, 2011, Circulation research.

Bone morphogenetic protein receptor type II deficiency and increased inflammatory cytokine production. A gateway to pulmonary arterial hypertension.

N. Morrell, C. Shanahan, K. Bloch, 2015, American journal of respiratory and critical care medicine.

Nesprin-1 and actin contribute to nuclear and cytoskeletal defects in lamin A/C-deficient cardiomyopathy.

D. Fatkin, M. Feneley, C. Shanahan, 2011, Journal of molecular and cellular cardiology.

Calcium Phosphate Crystals Induce Cell Death in Human Vascular Smooth Muscle Cells: A Potential Mechanism in Atherosclerotic Plaque Destabilization

Alexandra E. Ewence, M. Bootman, J. Skepper, 2008, Circulation research.

Differential Gene Expression in Vascular Smooth Muscle Cells in Primary Atherosclerosis and In Stent Stenosis in Humans

M. Goddard, M. Bennett, C. Shanahan, 2002, Arteriosclerosis, thrombosis, and vascular biology.

Stromal cells of fibrodysplasia ossificans progressiva lesions express smooth muscle lineage markers and the osteogenic transcription factor Runx2/Cbfa‐1: clues to a vascular origin of heterotopic ossification?

C. Shanahan, F. Gannon, F. Kaplan, 2003, The Journal of pathology.

High Expression of Genes for Calcificati( in Human Atherosclerotic Plaques on-ri egulating Proteins

P. Weissberg, C. Shanahan, N. Cary, 2013 .

ER stress regulates alkaline phosphatase gene expression in vascular smooth muscle cells via an ATF4-dependent mechanism

C. Shanahan, Malgorzata Furmanik, M. Furmanik, 2018, BMC Research Notes.

Specific localization of nesprin-1-α2, the short isoform of nesprin-1 with a KASH domain, in developing, fetal and regenerating muscle, using a new monoclonal antibody

N. Duong, K. Mamchaoui, C. Shanahan, 2016, BMC Cell Biology.

Arterial “ in ﬂ ammaging ” drives vascular calci ﬁ cation in children on dialysis

C. Shanahan, J. Laycock, R. Shroff, 2021 .

Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies

M. Russo, A. Shah, E. Ehler, 2019, JCI insight.

Arterial “inflammaging” drives vascular calcification in children on dialysis

C. Shanahan, J. Laycock, R. Shroff, 2019, Kidney international.

calci fi cation in children on dialysis Arterial “ in fl ammaging ” drives vascular

D. A. Long, C. Shanahan, J. Laycock, 2019 .

Accumulation of prelamin A drives inflammation in the heart with implications for treatment of inherited and acquired cardiomyopathies

M. Russo, A. Shah, C. D. dos Remedios, 2018, bioRxiv.

Disruption of PCNA-lamins A/C interactions by prelamin A induces DNA replication fork stalling

C. Shanahan, A. Cobb, D. Warren, 2016, Nucleus.

BMP-9 regulates the osteoblastic differentiation and calcification of vascular smooth muscle cells through an ALK1 mediated pathway

C. Farquharson, V. Macrae, C. Shanahan, 2014, Journal of cellular and molecular medicine.

Nesprin-1/2: roles in nuclear envelope organisation, myogenesis and muscle disease.

C. Shanahan, L. Rao, Can Zhou, 2018, Biochemical Society transactions.

Novel Nuclear Nesprin-2 Variants Tether Active Extracellular Signal-regulated MAPK1 and MAPK2 at Promyelocytic Leukemia Protein Nuclear Bodies and Act to Regulate Smooth Muscle Cell Proliferation*

C. Shanahan, T. Tajsic, D. Warren, 2009, The Journal of Biological Chemistry.

Role for alkaline phosphatase as an inducer of vascular calcification in renal failure?

C. Shanahan, M. Schoppet, 2008, Kidney international.

N-terminal nesprin-2 variants regulate β-catenin signalling

Chen Li, Flavia Autore, C. Shanahan, 2016, Experimental cell research.

RNA granules and cytoskeletal links.

C. Shanahan, D. Rajgor, Dipen Rajgor, 2014, Biochemical Society transactions.

Muscle Cells In Vitro and In Vivo Smooth Muscle Cell Heterogeneity : Patterns of Gene Expression in Vascular Smooth

P. Weissberg, C. Shanahan, 1998 .

Citrate Occurs Widely in Healthy and Pathological Apatitic Biomineral: Mineralized Articular Cartilage, and Intimal Atherosclerotic Plaque and Apatitic Kidney Stones

C. Shanahan, G. Jackson, A. Rodgers, 2013, Calcified Tissue International.

Autophagy and matrix vesicles: new partners in vascular calcification.

C. Shanahan, 2013, Kidney international.

Crystallizing nanoparticles derived from vascular smooth muscle cells contain the calcification inhibitor osteoprotegerin.

L. Hofbauer, C. Shanahan, M. Schoppet, 2011, Biochemical and biophysical research communications.

Aquaporin-1 Is Expressed by Vascular Smooth Muscle Cells and Mediates Rapid Water Transport across Vascular Cell Membranes

P. Agre, J. Osbourn, P. Weissberg, 1999, Journal of Vascular Research.

Inhibition of TNF-α Reverses the Pathological Resorption Pit Profile of Osteoclasts from Patients with Acute Charcot Osteoarthropathy

M. Edmonds, P. Petrov, C. Shanahan, 2015, Journal of diabetes research.

Osteopontin expression and calcium content in human aortic valves.

J. Kennedy, D. Henrion, A. Tedgui, 2000, The Journal of thoracic and cardiovascular surgery.

Abstracts of the UK-Russia Researcher Links Workshop: Extracellular vesicles – mechanisms of biogenesis and roles in disease pathogenesis

V. Tkachuk, V. Aushev, S. Davidson, 2015, Journal of extracellular vesicles.

UK–Russia Researcher Links Workshop: extracellular vesicles – mechanisms of biogenesis and roles in disease pathogenesis, M.V. Lomonosov Moscow State University, Moscow, Russia, 1–5 March 2015

V. Tkachuk, V. Aushev, S. Davidson, 2015, Journal of extracellular vesicles.

Notch-Rho-cGMP interaction: common point of convergence in microvascular aging-related disease.

C. Shanahan, Caroline Cheng, A. Roks, 2021, Clinical science.

Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization

M. Mayr, C. Shanahan, J. Madine, 2022, Aging cell.

Molecular Mechanisms of Vascular Health: Insights From Vascular Aging and Calcification

R. Blumenthal, C. St. Hilaire, E. Aikawa, 2022, Arteriosclerosis, thrombosis, and vascular biology.

Role of Vascular Smooth Muscle Cell Plasticity and Interactions in Vessel Wall Inflammation

R. Foo, C. Shanahan, T. Kofidis, 2020, Frontiers in Immunology.

SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle Cells

S. Cox, C. Shanahan, C. Molenaar, 2020, Cells.

Vascular calcification in chronic kidney disease.

A. Levin, N. Yorioka, G. London, 2004, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Medial vascular calcification revisited: review and perspectives.

C. St. Hilaire, P. Lanzer, M. Thiriet, 2014, European heart journal.

Mechanistic insights into vascular calcification in CKD.

C. Shanahan, R. Shroff, D. Long, 2013, Journal of the American Society of Nephrology : JASN.

Apoptosis Regulates Human Vascular Calcification In Vitro: Evidence for Initiation of Vascular Calcification by Apoptotic Bodies

J. Skepper, M. Bennett, P. Weissberg, 2000, Circulation research.

Calcium regulation of vascular smooth muscle cell-derived matrix vesicles.

C. Shanahan, A. Kapustin, 2012, Trends in cardiovascular medicine.

Medial localization of mineralization-regulating proteins in association with Mönckeberg's sclerosis: evidence for smooth muscle cell-mediated vascular calcification.

P. Weissberg, C. Shanahan, N. Cary, 1999, Circulation.

Mechanisms of vascular calcification in renal disease.

C. Shanahan, 2005, Clinical nephrology.

Molecular mechanisms mediating vascular calcification: Role of matrix Gla protein (Review Article)

C. Shanahan, D. Proudfoot, 2006, Nephrology.

Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness

A. Durham, C. Shanahan, C. Giachelli, 2018, Cardiovascular research.

Extracellular Matrix Proteomics Reveals Interplay of Aggrecan and Aggrecanases in Vascular Remodeling of Stented Coronary Arteries

M. Jahangiri, M. Mayr, U. Mayr, 2018, Circulation.

Arterial Calcification in Chronic Kidney Disease: Key Roles for Calcium and Phosphate

C. Shanahan, C. Giachelli, A. Kapustin, 2011, Circulation research.

NMR Spectroscopy of Native and in Vitro Tissues Implicates PolyADP Ribose in Biomineralization

J. Skepper, R. Brooks, D. Slatter, 2014, Science.

Engineered In vitro Models for Pathological Calcification: Routes Toward Mechanistic Understanding

A. Mata, S. Nazhat, Elham Radvar, 2021, Advanced NanoBiomed Research.

High expression of genes for calcification-regulating proteins in human atherosclerotic plaques.

P. Weissberg, C. Shanahan, N. Cary, 1994, The Journal of clinical investigation.

Novel Use of a Dektak 150 Surface Profiler Unmasks Differences in Resorption Pit Profiles Between Control and Charcot Patient Osteoclasts

M. Edmonds, P. Petrov, C. Shanahan, 2014, Calcified Tissue International.

Identification of osteoglycin as a component of the vascular matrix. Differential expression by vascular smooth muscle cells during neointima formation and in atherosclerotic plaques.

J. Osbourn, P. Weissberg, C. Shanahan, 1997, Arteriosclerosis, thrombosis, and vascular biology.

The nuclear lamina in health and disease

S. Gonzalo, P. Askjaer, C. Shanahan, 2016, Nucleus.

Nesprins: intracellular scaffolds that maintain cell architecture and coordinate cell function?

P. Weissberg, C. Shanahan, D. Warren, 2005, Expert Reviews in Molecular Medicine.

Identification and Validation of Putative Nesprin Variants.

Flavia Autore, C. Shanahan, Qiuping Zhang, 2016, Methods in molecular biology.

Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores

D. Navajas, Pere Roca-Cusachs, X. Trepat, 2017, Cell.

Nesprin‐1 and nesprin‐2 regulate endothelial cell shape and migration

A. Ridley, K. Nowak, C. Shanahan, 2014, Cytoskeleton.

Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α‐mediated stress signaling

Min Zhang, A. Shah, R. Brandes, 2016, The EMBO journal.

Identification of novel nesprin-1 binding partners and cytoplasmic matrin-3 in processing bodies

C. Shanahan, D. Rajgor, J. G. Hanley, 2016, Molecular biology of the cell.

Endoplasmic Reticulum Stress in Arterial Smooth Muscle Cells: A Novel Regulator of Vascular Disease

C. Shanahan, M. Furmanik, 2017, Current cardiology reviews.

Paternal uniparental isodisomy of chromosome 6 causing a complex syndrome including complete IFN‐γ receptor 1 deficiency

J. Casanova, L. Abel, S. Lyonnet, 2010, American journal of medical genetics. Part A.

The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.

C. Shanahan, M. Greener, R. Roberts, 2002, Genomics.

SUN1 Interacts with Nuclear Lamin A and Cytoplasmic Nesprins To Provide a Physical Connection between the Nuclear Lamina and the Cytoskeleton

R. Trembath, A. Fry, C. Shanahan, 2006, Molecular and Cellular Biology.

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

Juliet A. Ellis, B. Schlotter-Weigel, J. Skepper, 2007, Human molecular genetics.

The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton*

J. Lammerding, B. Burke, K. Roux, 2011, The Journal of Biological Chemistry.

Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.

Juliet A. Ellis, C. Shanahan, J. A. Ellis, 2007, Experimental cell research.

Coupling of the nucleus and cytoplasm: role of the LINC complex

D. Hodzic, J. B. Rattner, B. Burke, 2020 .

Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification

C. Reutelingsperger, L. Schurgers, U. Hedin, 2020, Circulation research.

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle

S. Shirran, C. Shanahan, C. Sewry, 2019, Scientific Reports.

Nesprins: Tissue-Specific Expression of Epsilon and Other Short Isoforms

N. Duong, C. Shanahan, C. Sewry, 2014, PloS one.

Nesprins LINC the nucleus and cytoskeleton.

C. Shanahan, D. Warren, J. Mellad, 2011, Current opinion in cell biology.

Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle

Juliet A. Ellis, J. Skepper, P. Weissberg, 2005, Journal of Cell Science.

Defective DNA-damage repair induced by nuclear lamina dysfunction is a key mediator of smooth muscle cell aging.

C. Shanahan, D. Warren, 2011, Biochemical Society transactions.

Multiple Novel Nesprin-1 and Nesprin-2 Variants Act as Versatile Tissue-Specific Intracellular Scaffolds

Flavia Autore, C. Shanahan, D. Rajgor, 2012, PloS one.

Endogenous Calcification Inhibitors in the Prevention of Vascular Calcification: A Consensus Statement From the COST Action EuroSoftCalcNet

G. Leftheriotis, V. Macrae, T. Arányi, 2019, Front. Cardiovasc. Med..

Vascular smooth muscle cell calcification is mediated by regulated exosome secretion.

M. Mayr, I. Drozdov, C. Reutelingsperger, 2015, Circulation research.

Macrophage-Derived Matrix Vesicles: An Alternative Novel Mechanism for Microcalcification in Atherosclerotic Plaques

Elena Aikawa, Manabu Shibasaki, Katsumi Yabusaki, 2013, Circulation research.

Cell Nuclei Spin in the Absence of Lamin B1*

Richard T. Lee, S. Young, C. Stewart, 2007, Journal of Biological Chemistry.

Magnesium Counteracts Vascular Calcification: Passive Interference or Active Modulation?

C. Shanahan, J. D. de Baaij, Anique D. ter Braake, 2017, Arteriosclerosis, thrombosis, and vascular biology.

Smooth muscle cell heterogeneity: patterns of gene expression in vascular smooth muscle cells in vitro and in vivo.

P L Weissberg, P. Weissberg, C. Shanahan, 1998, Arteriosclerosis, thrombosis, and vascular biology.

HDL in children with CKD promotes endothelial dysfunction and an abnormal vascular phenotype.

L. Rohrer, D. Fliser, U. Landmesser, 2014, Journal of the American Society of Nephrology : JASN.

Vitamin K-Antagonists Accelerate Atherosclerotic Calcification and Induce a Vulnerable Plaque Phenotype

C. Reutelingsperger, L. Schurgers, W. Jahnen-Dechent, 2012, PloS one.

Prelamin A Accelerates Vascular Calcification Via Activation of the DNA Damage Response and Senescence-Associated Secretory Phenotype in Vascular Smooth Muscle Cells

I. Drozdov, C. Shanahan, R. Shroff, 2013, Circulation research.

Lamin A/C controls nuclear matrin-3 levels and localization, but not alternative splicing of cassette exons

C. Gooding, Christopher W. J. Smith, R. Hayward, 2018, bioRxiv.

Novel nesprin-1 mutations associated with dilated cardiomyopathy cause nuclear envelope disruption and defects in myogenesis

Glenn E. Morris, Ziyuan Lin, Huaqin Sun, 2017, Human molecular genetics.

Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells: A role for spleen tyrosine kinase and exosome release

M. Bootman, S. Cook, M. Epple, 2018, Journal of molecular and cellular cardiology.

What Does the Pathology of Calcification in PAD Tell Us About the Disease Process ?

C. Shanahan, Chin Yee Ho, Catherine M. Shanahan, 2016 .

The Nuclear Envelope in Cardiac Health and Disease

C. Shanahan, Daniel Brayson, 2015 .

Glycation changes molecular organization and charge distribution in type I collagen fibrils

Lucy J. Colwell, G. Schitter, J. Skepper, 2020, Scientific Reports.

Nesprins: from the nuclear envelope and beyond

C. Shanahan, D. Rajgor, Dipen Rajgor, 2013, Expert Reviews in Molecular Medicine.

The Role of Chronic Kidney Disease in Ectopic Calcification

L. Schurgers, C. Shanahan, J. Laycock, 2020 .

DNA Damage Response

D. Towler, C. Shanahan, A. Cobb, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Prelamin A Accumulation Attenuates Rac1 Activity and Increases the Intrinsic Migrational Persistence of Aged Vascular Smooth Muscle Cells

C. Shanahan, D. Warren, M. Holt, 2016, Cells.

Krüppel-like Factor 4 (KLF4/GKLF) Is a Target of Bone Morphogenetic Proteins and Transforming Growth Factor β1 in the Regulation of Vascular Smooth Muscle Cell Phenotype*

P. Weissberg, C. Shanahan, K. E. King, 2003, The Journal of Biological Chemistry.

Matrix stiffness and blood pressure together regulate vascular smooth muscle cell phenotype switching

C. Shanahan, Cheng-han Yu, Ioannis Xanthis, 2020, bioRxiv.

The Effects of Serum Mg 2 + Concentration on Cardiovascular Disease Occurrence in the General Population

C. Shanahan, J. Baaij, A. D. T. Braake, 2017 .

Essential but sparse collagen hydroxylysyl post-translational modifications detected by DNP NMR.

H. Oschkinat, R. Hayward, C. Shanahan, 2018, Chemical communications.

Aspects of nuclear envelope dynamics in mitotic cells.

D. Salina, B. Burke, C. Shanahan, 2005, Novartis Foundation symposium.

Neointimal Hyperplasia and Calcification in Medium Sized Arteries in Adult Patients with Chronic Kidney Disease

C. Shanahan, A. Kapustin, D. Banerjee, 2015, Seminars in dialysis.

Chronic kidney disease and valvular heart disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

L. Newby, A. Webster, C. Sabanayagam, 2019, Kidney international.

Diseases of the Aorta and Kidney Disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

M. Jadoul, W. Winkelmayer, K. Johansen, 2021, Cardiovascular research.

Lamin A precursor localizes to the Z-disc of sarcomeres in the heart and is dynamically regulated in muscle cell differentiation

C. Shanahan, Daniel Brayson, 2022, Philosophical Transactions of the Royal Society B.

Not all vascular smooth muscle cell exosomes calcify equally in chronic kidney disease.

M. Colombo, C. Shanahan, A. Dusso, 2018, Kidney international.

ER stress regulates alkaline phosphatase gene expression in vascular smooth muscle cells via an ATF4-dependent mechanism

C. Shanahan, M. Furmanik, 2018, BMC research notes.

Smooth muscle cell phenotypes in atherosclerotic lesions.

P. Weissberg, C. Shanahan, C. Shanahan, 1999, Current Opinion in Lipidology.

Isolation of gene markers of differentiated and proliferating vascular smooth muscle cells.

P L Weissberg, P. Weissberg, C. Shanahan, 1993, Circulation research.

Filamentous nuclear actin regulation of PML NBs during the DNA damage response is deregulated by prelamin A

R. Hayward, C. Shanahan, R. Grosse, 2022, Cell death & disease.

Lipids in biocalcification: contrasts and similarities between intimal and medial vascular calcification and bone by NMR[S]

R. Brooks, C. Shanahan, M. Schoppet, 2012, Journal of Lipid Research.

Mammalian microtubule P-body dynamics are mediated by nesprin-1

J. B. Rattner, M. Fritzler, C. Shanahan, 2014, The Journal of cell biology.

Phosphodiesterase 1 regulation is a key mechanism in vascular aging.

O. Franco, A. Dehghan, C. O’Donnell, 2015, Clinical science.

Inflammation ushers in calcification: a cycle of damage and protection?

C. Shanahan, Catherine M Shanahan, 2007, Circulation.

Calcium and osteoprotegerin regulate IGF1R expression to inhibit vascular calcification.

T. Rachner, C. Shanahan, M. Schoppet, 2011, Cardiovascular research.

Vascular calcification and hypertension: Cause and effect

C. Shanahan, S. Kalra, 2012, Annals of medicine.

LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration

P. Paul-Gilloteaux, P. Chavrier, P. Maiuri, 2018, Nature Communications.

Nesprin-1: novel regulator of striated muscle nuclear positioning and mechanotransduction

C. Shanahan, Zhijuan Fan, Qiuping Zhang, 2023, Biochemical Society transactions.

Muscle tensions merge to cause a DNA replication crisis

C. Shanahan, C. Ho, Daniel Brayson, 2018, The Journal of cell biology.

Sox9 Regulates Extracellular Matrix Stiffness during Vascular Smooth Muscle Cell ageing by increased secretion of LH3 via extracellular vesicles.

S. Cox, Shanahan, C. Shanahan, 2023 .

A Polymorphism of the Human Matrix γ-Carboxyglutamic Acid Protein Promoter Alters Binding of an Activating Protein-1 Complex and Is Associated with Altered Transcription and Serum Levels*

P. Weissberg, C. Shanahan, Shiu-Wan Chan, 2001, The Journal of Biological Chemistry.

162 Regulated Exosome Secretion by Vascular Smooth Muscle Cells Mediates Vascular Calcification

M. Mayr, I. Drozdov, L. Schurgers, 2014, Heart.

TGF-β superfamily members do not promote smooth muscle-specific alternative splicing, a late marker of vascular smooth muscle cell differentiation

C. Shanahan, K. E. King-Briggs, 2000 .

Design considerations for engineering 3D models to study vascular pathologies in vitro

P. Lamata, C. Shanahan, R. Shipley, 2021, Acta biomaterialia.

Inflammation and gut dysbiosis as drivers of CKD–MBD

P. Stenvinkel, C. Shanahan, P. Evenepoel, 2023, Nature Reviews Nephrology.

Citrate Occurs Widely in Healthy and Pathological Apatitic Biomineral: Mineralized Articular Cartilage, and Intimal Atherosclerotic Plaque and Apatitic Kidney Stones

C. Shanahan, G. Jackson, A. Rodgers, 2013, Calcified Tissue International.

Sox9 accelerates vascular ageing by regulating extracellular matrix composition and stiffness

S. Cox, C. Shanahan, S. Lynham, 2023, bioRxiv.

Vascular smooth muscle cell phenotypic plasticity and the regulation of vascular calcification

P. Weissberg, C. Shanahan, C. Shanahan, 2006, Journal of internal medicine.

Acetylated Low-Density Lipoprotein Stimulates Human Vascular Smooth Muscle Cell Calcification by Promoting Osteoblastic Differentiation and Inhibiting Phagocytosis

J. Skepper, C. Shanahan, C. Shanahan, 2002, Circulation.

The role of apoptosis in the initiation of vascular calcification

J. Skepper, P. Weissberg, C. Shanahan, 2001, Zeitschrift für Kardiologie.

Chronic Kidney Disease and Coronary Artery Disease: JACC State-of-the-Art Review.

L. Newby, A. Webster, T. Marwick, 2019, Journal of the American College of Cardiology.

Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques

A. Didangelos, M. Mayr, A. Davies, 2017, The Journal of clinical investigation.

Calcification of human vascular cells in vitro is correlated with high levels of matrix Gla protein and low levels of osteopontin expression.

J. Skepper, P. Weissberg, C. Shanahan, 1998, Arteriosclerosis, thrombosis, and vascular biology.

Edinburgh Research Explorer Endogenous Calcification Inhibitors in the Prevention of Vascular Calcification

G. Leftheriotis, V. Macrae, T. Arányi, 2019 .

Vascular calcification and osteoporosis—from clinical observation towards molecular understanding

L. Hofbauer, C. Shanahan, M. Schoppet, 2007, Osteoporosis International.

Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques

A. Didangelos, M. Mayr, B. Paulweber, 2017 .

Extracellular vesicles stimulate smooth muscle cell migration by presenting collagen VI

A. Clayton, M. Humphries, F. Verweij, 2023, bioRxiv.

Emerging roles for vascular smooth muscle cell exosomes in calcification and coagulation

C. Shanahan, A. Kapustin, C. Shanahan, 2016, The Journal of physiology.

Nox 4 inhibits GADD 34-bound PP 1 to regulate eIF 2 a

Dina, Narayana, Anilkumar, 2016 .

Medial calcification in intact human arteries from children with chronic kidney disease is associated with apoptosis and osteogenic differentiation clinical and laboratory correlations

N. Figg, J. Deanfield, C. Shanahan, 2007 .

Abstract 10866: Novel Role of Macrophage-derived Matrix Vesicles in Arterial Microcalcification

E. Aikawa, K. Croce, M. Aikawa, 2011 .

Specific localization of nesprin-1-α2, the short isoform of nesprin-1 with a KASH domain, in developing, fetal and regenerating muscle, using a new monoclonal antibody

N. Duong, K. Mamchaoui, C. Shanahan, 2016, BMC Cell Biology.

HDL in children with CKD promotes endothelial dysfunction and an abnormal vascular phenotype.

L. Rohrer, D. Fliser, U. Landmesser, 2014, Journal of the American Society of Nephrology : JASN.

Prelamin A Acts to Accelerate Smooth Muscle Cell Senescence and Is a Novel Biomarker of Human Vascular Aging

J. Skepper, N. Figg, C. Shanahan, 2010, Circulation.

Neointimal Hyperplasia and Calcification in Medium Sized Arteries in Adult Patients with Chronic Kidney Disease

C. Shanahan, A. Kapustin, D. Banerjee, 2015, Seminars in dialysis.

Calcium Phosphate Crystals Induce Cell Death in Human Vascular Smooth Muscle Cells: A Potential Mechanism in Atherosclerotic Plaque Destabilization

Alexandra E. Ewence, M. Bootman, J. Skepper, 2008, Circulation research.

Nesprins LINC the nucleus and cytoskeleton.

C. Shanahan, D. Warren, J. Mellad, 2011, Current opinion in cell biology.

Mouse models of nesprin-related diseases.

C. Shanahan, D. Warren, L. Rao, 2018, Biochemical Society transactions.

Nesprin‐1 and nesprin‐2 regulate endothelial cell shape and migration

A. Ridley, K. Nowak, C. Shanahan, 2014, Cytoskeleton.

Novel Use of a Dektak 150 Surface Profiler Unmasks Differences in Resorption Pit Profiles Between Control and Charcot Patient Osteoclasts

M. Edmonds, P. Petrov, C. Shanahan, 2013, Calcified Tissue International.

Identification and Validation of Putative Nesprin Variants.

Flavia Autore, C. Shanahan, Qiuping Zhang, 2016, Methods in molecular biology.

MINERAL ION-INDUCED RELEASE OF MINERALIZATION-COMPETENT MATRIX VESICLES FROM HUMAN VASCULAR SMOOTH MUSCLE CELLS

J. Skepper, C. Shanahan, D. Proudfoot, 2004 .

Nanocrystals seed calcification in more ways than one.

C. Shanahan, D. Proudfoot, 2011, Kidney International.

BS47 Role of vascular smooth muscle cell-derived exosomes in age-related vascular amyloidosis

C. Shanahan, M. Whitehead, Sadia Ahmad, 2019, Basic Science.