R. Vanbever

发表

Skin electroporation for transdermal and topical delivery.

Véronique Préat, V. Préat, A. Denet, 2004, Advanced drug delivery reviews.

Recent Advances in Skin Electroporation: Mechanism and Efficacy

J. Weaver, M. Prausnitz, T. Gowrishankar, 1999 .

Comparison of Iontophoresis and Electroporation: Mechanisms and Tolerance

V. Préat, R. Vanbever, A. Jadoul, 1999 .

Comparison of the effects of short, high-voltage and long, medium-voltage pulses on skin electrical and transport properties.

J. Weaver, V. Préat, U. Pliquett, 1999, Journal of controlled release : official journal of the Controlled Release Society.

Heparin alters transdermal transport associated with electroporation.

J. Weaver, M. Prausnitz, R. Vanbever, 1997, Biochemical and biophysical research communications.

Influence of formulation excipients and physical characteristics of inhalation dry powders on their aerosolization performance.

V. Préat, C. Lombry, R. Vanbever, 2001, Journal of controlled release : official journal of the Controlled Release Society.

Minimal amounts of dipalmitoylphosphatidylcholine improve aerosol performance of spray-dried temocillin powders for inhalation.

C. Dupont-Gillain, R. Vanbever, B. Cuvelier, 2015, International journal of pharmaceutics.

Influenza virus;

E. Hamelmann, R. Vanbever, J. Jaworska, 2008 .

Pulmonary delivery of growth hormone using dry powders and visualization of its local fate in rats.

V. Préat, R. Vanbever, C. Bosquillon, 2004, Journal of controlled release : official journal of the Controlled Release Society.

Impact of formulation and methods of pulmonary delivery on absorption of parathyroid hormone (1-34) from rat lungs.

V. Préat, R. Vanbever, F. Vanderbist, 2004, Journal of pharmaceutical sciences.

In vivo Noninvasive Evaluation of Hairless Rat Skin after High-Voltage Pulse Exposure

V. Préat, R. Vanbever, A. Jadoul, 1998, Skin Pharmacology and Physiology.

Large Porous Particles for Sustained Protection from Carbachol-Induced Bronchoconstriction in Guinea Pigs

R. Langer, A. Ben-Jebria, R. Vanbever, 1999, Pharmaceutical Research.

Formulation and Physical Characterization of Large Porous Particles for Inhalation

R. Langer, R. Vanbever, D. A. Edwards, 1999, Pharmaceutical Research.

Nicotinamide enhances apoptosis of G(M)-CSF-treated neutrophils and attenuates endotoxin-induced airway inflammation in mice.

A. Neyrinck, N. Delzenne, R. Vanbever, 2011, American journal of physiology. Lung cellular and molecular physiology.

Performance-driven, pulmonary delivery of systemically acting drugs.

R. Vanbever, 2005, Drug discovery today. Technologies.

PEGylation, an approach for improving the pulmonary delivery of biopharmaceuticals

R. Vanbever, T. Leal, Marie-Julie Guichard, 2017 .

Aerosol delivery with two ventilation modes during mechanical ventilation: a randomized study

P. Hantson, C. Raftopoulos, F. Jamar, 2016, Annals of Intensive Care.

Local and Systemic Immune Responses to Intratracheal Instillation of Antigen and DNA Vaccines in Mice

J. Renauld, D. Lison, V. Préat, 2004, Pharmaceutical Research.

Mucosal and Systemic Immune Responses to Mycobacterium tuberculosis Antigen 85A following Its Co-Delivery with CpG, MPLA or LTB to the Lungs in Mice

J. Renauld, R. Vanbever, K. Huygen, 2013, PloS one.

Respiratory hazard of Li-ion battery components: elective toxicity of lithium cobalt oxide (LiCoO2) particles in a mouse bioassay

D. Lison, E. Marbaix, J. Rose, 2018, Archives of Toxicology.

Airway delivery of low-dose miglustat normalizes nasal potential difference in F508del cystic fibrosis mice.

P. Lebecque, R. Vanbever, P. Wallemacq, 2009, American journal of respiratory and critical care medicine.

Encapsulation of a CpG oligonucleotide in cationic liposomes enhances its local antitumor activity following pulmonary delivery in a murine model of metastatic lung cancer.

J. Renauld, K. Vanvarenberg, R. Vanbever, 2021, International journal of pharmaceutics.

Activity of Antibiotics against Staphylococcus aureus in an In Vitro Model of Biofilms in the Context of Cystic Fibrosis: Influence of the Culture Medium

R. Vanbever, T. Wilms, F. Van Bambeke, 2019, Antimicrobial Agents and Chemotherapy.

Therapeutic monoclonal antibodies for respiratory diseases: Current challenges and perspectives, March 31 – April 1, 2016, Tours, France

P. Diot, B. Ryffel, J. Reichert, 2016, mAbs.

HIF-1α is a key mediator of the lung inflammatory potential of lithium-ion battery particles

D. Lison, R. Vanbever, F. Huaux, 2019, Particle and Fibre Toxicology.

Systemic delivery of parathyroid hormone (1-34) using inhalation dry powders in rats.

D. Lison, V. Préat, R. Vanbever, 2003, Journal of pharmaceutical sciences.

PEGylation of recombinant human deoxyribonuclease I deceases its transport across lung epithelial cells and uptake by macrophages.

K. Braeckmans, S. D. De Smedt, H. De Keersmaecker, 2020, International journal of pharmaceutics.

PEGylation of Recombinant Human Deoxyribonuclease I Provides a Long‐Acting Version of the Mucolytic for Patients with Cystic Fibrosis

E. Marbaix, K. Vanvarenberg, R. Vanbever, 2020 .

Sirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages.

A. Neyrinck, N. Delzenne, R. Vanbever, 2012, Biochemical and biophysical research communications.

Peptides and Proteins: Pulmonary Absorption

R. Vanbever, S. Koussoroplis, 2013 .

Confocal imaging of rat lungs following intratracheal delivery of dry powders or solutions of fluorescent probes.

V. Préat, C. Lombry, R. Vanbever, 2002, Journal of controlled release : official journal of the Controlled Release Society.

Fate of nanomedicines in the lungs

R. Vanbever, Julie Todoroff, 2011 .

Cationic Nanoliposomes Are Efficiently Taken up by Alveolar Macrophages but Have Little Access to Dendritic Cells and Interstitial Macrophages in the Normal and CpG-Stimulated Lungs.

K. Vanvarenberg, R. Vanbever, F. Huaux, 2019, Molecular pharmaceutics.

Impact of the PEG length and PEGylation site on the structural, thermodynamic, thermal, and proteolytic stability of mono‐PEGylated alpha‐1 antitrypsin

R. Vanbever, M. Dumoulin, Xiao Liu, 2022, Protein science : a publication of the Protein Society.

Intranasal delivery of whole influenza vaccine prevents subsequent allergen‐induced sensitization and airway hyper‐reactivity in mice

P. Matricardi, E. Hamelmann, R. Vanbever, 2007, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Production and characterization of mono-PEGylated alpha-1 antitrypsin for augmentation therapy

K. Vanvarenberg, R. Vanbever, Xiao Liu, 2021, International Journal of Pharmaceutics.

Molecular Transport across Stratum Corneum due to Electric Pulses:Behavior of Localized Transport Regions (LTRS)

G. T. Martin, J. Weaver, V. Préat, 1999 .

Transdermal permeation of neutral molecules by skin electroporation.

V. Préat, R. Vanbever, M. LeRoy, 1998, Journal of controlled release : official journal of the Controlled Release Society.

Skin Electroporation for Transdermal Drug Delivery

J. Weaver, V. Préat, R. Vanbever, 1999 .

Optimization of the aerosolization properties of an inhalation dry powder based on selection of excipients.

R. Vanbever, A. Minne, Hélène Boireau, 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Impact of PEGylation on the mucolytic activity of recombinant human deoxyribonuclease I in cystic fibrosis sputum.

P. Lebecque, F. Vermeulen, R. Vanbever, 2018, Clinical science.

Needle-free iontophoresis-driven β-adrenergic sweat rate test.

P. Lebecque, F. Vermeulen, A. Mottais, 2021, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Advax augments B and T cell responses upon influenza vaccination via the respiratory tract and enables complete protection of mice against lethal influenza virus challenge

W. Hinrichs, H. Frijlink, N. Petrovsky, 2018, Journal of Controlled Release.

Physical Characterization of Large Porous Particles for Inhalation

R. Gupta, R. Langer, R. Vanbever, 2000, Pharmaceutical Research.

Synthesis and In Vitro Evaluation of Polyethylene Glycol-Paclitaxel Conjugates for Lung Cancer Therapy

C. Alexander, V. Préat, R. Vanbever, 2016, Pharmaceutical Research.

Analysis of sialoadhesin expression on mouse alveolar macrophages.

R. Vanbever, P. Crocker, J. Ducreux, 2009, Immunology letters.

The delivery site of a monovalent influenza vaccine within the respiratory tract impacts on the immune response

J. Renauld, R. Vanbever, J. Louahed, 2007, Immunology.

Protein Engineering Strategies for Improved Pharmacokinetics

R. Vanbever, M. Dumoulin, Francisco Morales-Yánez, 2021, Advanced Functional Materials.

Alveolar macrophages are a primary barrier to pulmonary absorption of macromolecules.

Véronique Préat, V. Préat, C. Lombry, 2004, American journal of physiology. Lung cellular and molecular physiology.

Delivery strategies for sustained drug release in the lungs.

R. Vanbever, C. Loira-Pastoriza, Rita Vanbever, 2014, Advanced drug delivery reviews.

Aerosolization properties, surface composition and physical state of spray-dried protein powders.

P. Rouxhet, V. Préat, R. Vanbever, 2004, Journal of controlled release : official journal of the Controlled Release Society.

Mind your assays: Misleading cytotoxicity with the WST-1 assay in the presence of manganese

D. Lison, R. Vanbever, P. Jacques, 2020, PloS one.

Fate of PEGylated antibody fragments following delivery to the lungs: Influence of delivery site, PEG size and lung inflammation

Gregg A. Duncan, J. S. Suk, J. Hanes, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Transdermal delivery of fentanyl: rapid onset of analgesia using skin electroporation.

V. Préat, R. Vanbever, S. Montmayeur, 1998, Journal of controlled release : official journal of the Controlled Release Society.

SPECT-CT Comparison of Lung Deposition using a System combining a Vibrating-mesh Nebulizer with a Valved Holding Chamber and a Conventional Jet Nebulizer: a Randomized Cross-over Study

Michel Hesse, François Jamar, Gregory Reychler, 2017, Pharmaceutical Research.

Preclinical models for pulmonary drug delivery

R. Vanbever, Rita Vanbever, Cláudia A Fernandes, 2009, Expert opinion on drug delivery.

Comparison of particle sizing techniques in the case of inhalation dry powders.

V. Préat, C. Lombry, R. Vanbever, 2001, Journal of pharmaceutical sciences.

Targeting the deep lungs, Poloxamer 407 and a CpG oligonucleotide optimize immune responses to Mycobacterium tuberculosis antigen 85A following pulmonary delivery.

J. Renauld, R. Vanbever, B. Ucakar, 2013, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

PEGylation of paclitaxel largely improves its safety and anti-tumor efficacy following pulmonary delivery in a mouse model of lung carcinoma.

R. Vanbever, C. Bosquillon, C. Loira-Pastoriza, 2016, Journal of controlled release : official journal of the Controlled Release Society.

PEGylation of anti-sialoadhesin monoclonal antibodies enhances their inhibitory potencies without impairing endocytosis in mouse peritoneal macrophages.

P. Courtoy, R. Vanbever, P. Crocker, 2009, Bioconjugate chemistry.

The inhibitory potencies of monoclonal antibodies to the macrophage adhesion molecule sialoadhesin are greatly increased following PEGylation.

R. Vanbever, P. Crocker, J. Ducreux, 2008, Bioconjugate chemistry.

The particle has landed--characterizing the fate of inhaled pharmaceuticals.

M. Gumbleton, J. Patton, C. Ehrhardt, 2010, Journal of aerosol medicine and pulmonary drug delivery.

Production and characterization of a PEGylated derivative of recombinant human deoxyribonuclease I for cystic fibrosis therapy.

R. Vanbever, R. Wattiez, Harshad P. Patil, 2017, International journal of pharmaceutics.

Biodistribution and elimination pathways of PEGylated recombinant human deoxyribonuclease I after pulmonary delivery in mice.

R. Vanbever, T. Wilms, C. Bosquillon, 2020, Journal of controlled release : official journal of the Controlled Release Society.

PEGylation of antibody fragments greatly increases their local residence time following delivery to the respiratory tract.

C. Uyttenhove, J. Van Snick, R. Vanbever, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Production, purification and biological characterization of mono-PEGylated anti-IL-17A antibody fragments.

C. Uyttenhove, J. Van Snick, R. Vanbever, 2013, International journal of pharmaceutics.

Synthesis and In Vitro Evaluation of Polyethylene Glycol-Paclitaxel Conjugates for Lung Cancer Therapy

C. Alexander, V. Préat, R. Vanbever, 2016, Pharmaceutical Research.

Respiratory hazard of Li-ion battery components: elective toxicity of lithium cobalt oxide (LiCoO2) particles in a mouse bioassay

D. Lison, E. Marbaix, J. Rose, 2018, Archives of Toxicology.

Mechanistic studies of skin electroporation using biophysical methods.

M. Prausnitz, U. Pliquett, R. Vanbever, 2000, Methods in molecular medicine.

Preclinical evaluation of topically-administered PEGylated Fab’ lung toxicity

J. Van Snick, R. Vanbever, D. Cataldo, 2019, International journal of pharmaceutics: X.

Creation of transdermal pathways for macromolecule transport by skin electroporation and a low toxicity, pathway-enlarging molecule.

J. Weaver, R. Langer, U. Pliquett, 1999, Bioelectrochemistry and bioenergetics.

Transdermal Delivery of Fentanyl by Electroporation I. Influence of Electrical Factors

Véronique Préat, V. Préat, R. Vanbever, 1996, Pharmaceutical Research.

Factors affecting transdermal delivery of metoprolol by electroporation

V. Préat, R. Vanbever, 1995 .

Optimization of Dry Powder Aerosols for Systemic Drug Delivery

R. Vanbever, 2003 .

Nebulization of PEGylated recombinant human deoxyribonuclease I using vibrating membrane nebulizers: A technical feasibility study.

H. Frijlink, K. Vanvarenberg, R. Vanbever, 2023, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

LOCAL TRANSPORT REGIONS (LTRS) IN HUMAN STRATUM CORNEUM DUE TO LONG AND SHORT 'HIGH VOLTAGE' PULSES

James C. Weaver, Véronique Préat, Uwe Pliquett, 1998 .

Macromolecules as Novel Transdermal Transport Enhancers for Skin Electroporation

M. Prausnitz, V. Préat, R. Vanbever, 1997, Pharmaceutical Research.

Pulmonary immunization: deposition site is of minor relevance for influenza vaccination but deep lung deposition is crucial for hepatitis B vaccination

W. Hinrichs, H. Frijlink, R. Vanbever, 2019, Acta pharmaceutica Sinica. B.

PEGylation prolongs the pulmonary retention of an anti-IL-17A Fab' antibody fragment after pulmonary delivery in three different species.

C. Uyttenhove, R. Vanbever, S. Heywood, 2017, International journal of pharmaceutics.

Improving the efficacy of inhaled drugs for severe lung diseases: emerging pulmonary delivery strategies.

F. Ungaro, R. Vanbever, 2014, Advanced Drug Delivery Reviews.

The particle has landed--characterizing the fate of inhaled pharmaceuticals.

M. Gumbleton, J. Patton, C. Ehrhardt, 2010, Journal of aerosol medicine and pulmonary drug delivery.