E. Sommer

发表

Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

Michael J. Munson, Dario R. Alessi, A. Prescott, 2014, The Biochemical journal.

Characterization of GSK 2334470 , a novel and highly specific inhibitor of PDK 1

D. Alessi, E. Sommer, J. Axten, 2010 .

Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney.

D. Alessi, K. Sakamoto, S. Wullschleger, 2011, The Biochemical journal.

The hVps34‐SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth

J. Baselga, P. Eyers, D. Alessi, 2016, The EMBO journal.

PRR5L degradation promotes MTORC2-mediated PKCδ phosphorylation and cell migration downstream of Gα12

M. Simon, S. Srinivasula, Dianqing Wu, 2012, Nature Cell Biology.

The hVps34‐SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth

J. Baselga, P. Eyers, D. Alessi, 2016, The EMBO journal.

University of Dundee The hVPS 34-SGK 3 pathway counteracts inhibition of the PI 3 K-Akt to maintain mTORC 1 and tumour growth

J. Baselga, P. Eyers, D. Alessi, 2016 .

Characterization of VPS 34-IN 1 , a selective inhibitor of Vps 34 , reveals that the phosphatidylinositol 3-phosphate-binding SGK 3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

A. Prescott, D. Alessi, R. Ward, 2014 .

Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

Michael J. Munson, A. Prescott, D. Alessi, 2014, The Biochemical journal.

Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors

Dario R. Alessi, D. Alessi, S. Guichard, 2013, The Biochemical journal.

A novel class of autoantigens of anti-neutrophil cytoplasmic antibodies in necrotizing and crescentic glomerulonephritis: the lysosomal membrane glycoprotein h-lamp-2 in neutrophil granulocytes and a related membrane protein in glomerular endothelial cells

G. Schaffner, S. Binder, D. Kerjaschki, 1995, The Journal of experimental medicine.

Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1.

Ayaz Najafov, Dario R Alessi, D. Alessi, 2011, The Biochemical journal.

Abstract A04: Characterization of VPS34-IN1, a specific inhibitor of Vps34 reveals that the phosphatidylinositol 3-phosphate binding SGK3 protein kinase is regulated by class III PI-3 kinase

A. Prescott, D. Alessi, I. Ganley, 2015 .