P. Nighot

发表

Chloride channel ClC-2 modulates tight junction barrier function via intracellular trafficking of occludin.

A. Blikslager, P. Nighot, 2012, American journal of physiology. Cell physiology.

Lactobacillus acidophilus induces a strain-specific and toll-like receptor-2 dependent enhancement of intestinal epithelial tight junction barrier and protection against intestinal inflammation.

P. Nighot, M. Haque, Manmeet Rawat, 2021, The American journal of pathology.

Bifidobacterium bifidum Enhances the Intestinal Epithelial Tight Junction Barrier and Protects against Intestinal Inflammation by Targeting the Toll-like Receptor-2 Pathway in an NF-κB-Independent Manner

P. Nighot, Shuhong Guo, T. Ma, 2021, International journal of molecular sciences.

Diclofenac poisoning is widespread in declining vulture populations across the Indian subcontinent

R. Green, D. Pain, P. Nighot, 2004, Proceedings of the Royal Society of London. Series B: Biological Sciences.

Recovery of mucosal barrier function in ischemic porcine ileum and colon is stimulated by a novel agonist of the ClC-2 chloride channel, lubiprostone.

A. Blikslager, P. Nighot, R. Ueno, 2007, American journal of physiology. Gastrointestinal and liver physiology.

Role of autophagy in the regulation of epithelial cell junctions

P. Nighot, T. Ma, 2016, Tissue barriers.

Autophagy and Tight Junction 1 Autophagy Enhancement of Intestinal Epithelial Tight Junction Barrier Function by targeting Claudin-2 degradation

P. Nighot, Chien-An A Hu, T. Ma, 2015 .

Autophagy Enhances Intestinal Epithelial Tight Junction Barrier Function by Targeting Claudin-2 Protein Degradation*

P. Nighot, Chien-An A Hu, T. Ma, 2015, The Journal of Biological Chemistry.

Genotype in India Infectious Bronchitis Virus with a Novel Emergence of a Nephropathogenic Avian

J. Gelb, P. Nighot, B. Ladman, 2005 .

Emergence of a Nephropathogenic Avian Infectious Bronchitis Virus with a Novel Genotype in India

J. Gelb, P. Nighot, B. Ladman, 2005, Journal of Clinical Microbiology.

Lipopolysaccharide Regulation of Intestinal Tight Junction Permeability Is Mediated by TLR4 Signal Transduction Pathway Activation of FAK and MyD88

P. Nighot, Shuhong Guo, T. Ma, 2015, The Journal of Immunology.

Chloride Channel ClC-2 is a Key Factor in the Development of DSS-induced Murine Colitis

S. Plevy, A. Blikslager, P. Nighot, 2013, Inflammatory bowel diseases.

Mice lacking the Na+/H+ exchanger 2 have impaired recovery of intestinal barrier function.

A. Blikslager, P. Nighot, L. Clarke, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Lipopolysaccharide-Induced Increase in Intestinal Epithelial Tight Permeability Is Mediated by Toll-Like Receptor 4/Myeloid Differentiation Primary Response 88 (MyD88) Activation of Myosin Light Chain Kinase Expression.

P. Nighot, Manmeet Rawat, Shuhong Guo, 2017, The American journal of pathology.

Comparison of the chloride channel activator lubiprostone and the oral laxative Polyethylene Glycol 3350 on mucosal barrier repair in ischemic-injured porcine intestine.

B. Roerig, A. Blikslager, P. Nighot, 2008, World journal of gastroenterology.

Endocytosis of Intestinal Tight Junction Proteins: In Time and Space.

P. Nighot, T. Ma, 2020, Inflammatory bowel diseases.

Epigenetic Reprogramming by Somatic Cell Nuclear Transfer in Primates

S. Mitalipov, D. Wolf, P. Nighot, 2009, Stem cells.

Role of ClC-2 and NHE transport proteins in Intestinal Mucosal Barrier

P. Nighot, 2008 .

Genetic Ablation of the ClC-2 Cl- Channel Disrupts Mouse Gastric Parietal Cell Acid Secretion

A. Blikslager, J. Cuppoletti, P. Nighot, 2015, PloS one.

ClC-2 regulates mucosal barrier function associated with structural changes to the villus and epithelial tight junction.

A. Blikslager, P. Nighot, 2010, American journal of physiology. Gastrointestinal and liver physiology.

ClC-2 is required for rapid restoration of epithelial tight junctions in ischemic-injured murine jejunum.

Troy H. Ghashghaei, A. Blikslager, P. Nighot, 2009, Experimental cell research.

Gastrointestinal dysfunction induced by early weaning is attenuated by delayed weaning and mast cell blockade in pigs.

A. Blikslager, P. Nighot, A. Moeser, 2007, American journal of physiology. Gastrointestinal and liver physiology.

Proventriculitis: a concern in the field.

P. Nighot, G. N. Kolte, 2000 .

Intestinal epithelial tight junction barrier regulation by autophagy-related protein ATG6/beclin 1.

P. Nighot, Morgan Wong, T. Ma, 2019, American journal of physiology. Cell physiology.

Autophagy Increases Occludin Levels to Enhance Intestinal Paracellular Tight Junction Barrier

W. Koltun, P. Nighot, G. Yochum, 2022, bioRxiv.

AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability

W. Koltun, P. Nighot, G. Yochum, 2021, Autophagy.

Lipopolysaccharide-Induced Increase in Intestinal Permeability Is Mediated by TAK-1 Activation of IKK and MLCK/MYLK Gene.

P. Nighot, Manmeet Rawat, Eliseo F. Castillo, 2019, The American journal of pathology.

Chloride channel ClC‐ 2 enhances intestinal epithelial tight junction barrier function via regulation of caveolin‐1 and caveolar trafficking of occludin

P. Nighot, T. Ma, Lana Leung, 2017, Experimental cell research.

Matrix metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitis.

P. Nighot, Manmeet Rawat, D. Watterson, 2015, American journal of physiology. Gastrointestinal and liver physiology.

The mRNA-binding protein IGF2BP1 maintains intestinal barrier function by up-regulating occludin expression

D. Karamchandani, P. Nighot, G. Yochum, 2020, The Journal of Biological Chemistry.

Astrovirus infection induces sodium malabsorption and redistributes sodium hydrogen exchanger expression.

M. Koci, A. Blikslager, P. Nighot, 2010, Virology.

Prostaglandin-mediated inhibition of Na+/H+ exchanger isoform 2 stimulates recovery of barrier function in ischemia-injured intestine.

A. Blikslager, P. Nighot, A. Moeser, 2006, American journal of physiology. Gastrointestinal and liver physiology.

Matrix Metalloproteinase MMP-12 promotes macrophage transmigration across intestinal epithelial tight junctions and increases severity of experimental colitis.

P. Nighot, Eliseo F. Castillo, T. Ma, 2021, Journal of Crohn's & colitis.

Pathophysiology of avian intestinal ion transport

P. Nighot, M. Nighot, 2018, World's poultry science journal.

Oral Administration of Astrovirus Capsid Protein Is Sufficient To Induce Acute Diarrhea In Vivo

R. Heath, S. Schultz-Cherry, M. Koci, 2016, mBio.

Characterization of turkey inducible nitric oxide synthase and identification of its expression in the intestinal epithelium following astrovirus infection.

M. Koci, A. Blikslager, P. Nighot, 2012, Comparative immunology, microbiology and infectious diseases.

Biological Effect of Naturally Occurring Mycotoxins Fed to Poults Reared to 21 Days of Age

M. Koci, P. Nighot, J. Grimes, 2010 .

Efficacy of feed additives to reduce the effect of naturally occurring mycotoxins fed to turkey hen poults reared to 6 weeks of age

M. Koci, P. Nighot, J. Grimes, 2017, Poultry science.

Intestinal barrier dysfunction in human necrotizing enterocolitis.

S. Moore, P. Nighot, Manmeet Rawat, 2016, Journal of pediatric surgery.

TGF-β–Activated Kinase 1 Signaling Maintains Intestinal Integrity by Preventing Accumulation of Reactive Oxygen Species in the Intestinal Epithelium

J. Ninomiya-Tsuji, Kunihiro Matsumoto, A. Blikslager, 2010, The Journal of Immunology.

Contrasting effects of linaclotide and lubiprostone on restitution of epithelial cell barrier properties and cellular homeostasis after exposure to cell stressors

A. Blikslager, J. Cuppoletti, P. Nighot, 2012, BMC pharmacology.

Long term use of Proton Pump Inhibitor disrupts intestinal tight junction barrier and exaggerates experimental colitis.

W. Koltun, Shannon Dalessio, P. Nighot, 2022, Journal of Crohn's & colitis.

Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight junction barrier via AhR and Nrf2 pathways.

W. Koltun, T. Thompson, G. Perdew, 2023, Cell reports.

Autophagy Reduces the Degradation and Promotes Membrane Localization of Occludin to Enhance the Intestinal Epithelial Tight Junction Barrier against Paracellular Macromolecule Flux.

W. Koltun, P. Nighot, G. Yochum, 2022, Journal of Crohn's & colitis.

Alpha-tocopherylquinone-mediated activation of the Aryl Hydrocarbon Receptor regulates the production of inflammation-inducing cytokines and ameliorates intestinal inflammation

G. Perdew, P. Nighot, K. Saha, 2023, Mucosal immunology.

Matrix metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitis.

P. Nighot, Manmeet Rawat, D. Watterson, 2015, American journal of physiology. Gastrointestinal and liver physiology.

Astrovirus infection induces sodium malabsorption and redistributes sodium hydrogen exchanger expression.

M. Koci, A. Blikslager, P. Nighot, 2010, Virology.