J. C. de la Torre

发表

Different Mechanisms of Cell Entry by Human-Pathogenic Old World and New World Arenaviruses

S. Kunz, Jillian M. Rojek, Ana B. Sánchez, 2008, Journal of Virology.

The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: biological relevance--a review.

E. Domingo, R. Nájera, D. Steinhauer, 1985, Gene.

RNA virus populations as quasispecies.

J. Holland, D. Steinhauer, J. C. de la Torre, 1992, Current topics in microbiology and immunology.

Quantitation of relative fitness and great adaptability of clonal populations of RNA viruses

J. Holland, J. C. de la Torre, D. Clarke, 1991, Journal of virology.

Progression of type 1 diabetes from the prediabetic stage is controlled by interferon-α signaling

Brian C. Ware, J. C. de la Torre, M. Oldstone, 2017, Proceedings of the National Academy of Sciences.

Vaccination to prevent persistent viral infection

J. Whitton, J. C. de la Torre, M. Oldstone, 1993, Journal of virology.

Selective disruption of growth hormone transcription machinery by viral infection.

L. De, J. C. de la Torre, M. Oldstone, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Ube1L and Protein ISGylation Are Not Essential for Alpha/Beta Interferon Signaling

Ming Yan, Dong-er Zhang, J. C. de la Torre, 2006, Molecular and Cellular Biology.

RNA virus quasispecies: significance for viral disease and epidemiology.

S. Elena, A. Moya, E. Domingo, 1994, Infectious agents and disease.

Analysis of CD8+ T cell response during the 2013–2016 Ebola epidemic in West Africa

Karthik Gangavarapu, Augustine Goba, Donald S Grant, 2018, Proceedings of the National Academy of Sciences.

Mutation Frequencies at Defined Single Codon Sites in Vesicular Stomatitis Virus and Poliovirus Can Be Increased Only Slightly by Chemical Mutagenesis

David A. Steinhauer, John J. Holland, E. Domingo, 1990, Journal of virology.

RNA virus quasispecies populations can suppress vastly superior mutant progeny

J. Holland, J. C. de la Torre, J J Holland, 1990, Journal of virology.

Arenavirus Nucleoprotein Targets Interferon Regulatory Factor-Activating Kinase IKKε

S. Kunz, J. C. de la Torre, L. Martínez-Sobrido, 2012, Journal of Virology.

Type I interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection

J. C. de la Torre, D. Brooks, Douglas H. Yamada, 2014, Proceedings of the National Academy of Sciences.

Cell entry of lymphocytic choriomeningitis virus is restricted in myotubes.

J. C. de la Torre, Masaharu Iwasaki, N. Ngo, 2014, Virology.

Antiviral Activity of a Small-Molecule Inhibitor of Arenavirus Glycoprotein Processing by the Cellular Site 1 Protease

S. Kunz, A. Pasquato, J. C. de la Torre, 2010, Journal of Virology.

The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis.

U. V. von Andrian, D. Álvarez, U. V. Andrian, 2016, Immunity.

T cell ignorance in mice to Borna disease virus can be overcome by peripheral expression of the viral nucleoprotein.

H. Pircher, J. C. de la Torre, P. Staeheli, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Replication of lymphocytic choriomeningitis virus is restricted in terminally differentiated neurons

P. Borrow, P. Sanna, L. De, 1993, Journal of virology.

Self-Association of Lymphocytic Choriomeningitis Virus Nucleoprotein Is Mediated by Its N-Terminal Region and Is Not Required for Its Anti-Interferon Function

J. C. de la Torre, L. Martínez-Sobrido, Emilio Ortiz-Riaño, 2012, Journal of Virology.

Genetic and Biochemical Evidence for an Oligomeric Structure of the Functional L Polymerase of the Prototypic Arenavirus Lymphocytic Choriomeningitis Virus

Ana B. Sánchez, J. C. de la Torre, 2005, Journal of Virology.

Identification of Common CD8+ T Cell Epitopes from Lassa Fever Survivors in Nigeria and Sierra Leone

Pardis C Sabeti, Brian C. Ware, Brian C Ware, 2020, Journal of Virology.

Astrocytes are the primary source of tissue factor in the murine central nervous system. A role for astrocytes in cerebral hemostasis.

J. C. Torre, N. Mackman, D. Loskutoff, 1993, The Journal of clinical investigation.

NP and L Proteins of Lymphocytic Choriomeningitis Virus (LCMV) Are Sufficient for Efficient Transcription and Replication of LCMV Genomic RNA Analogs

J. C. de la Torre, M. Oldstone, M. Teng, 2000, Journal of Virology.

The Glycoprotein of the Live-Attenuated Junin Virus Vaccine Strain Induces Endoplasmic Reticulum Stress and Forms Aggregates prior to Degradation in the Lysosome

J. C. de la Torre, T. Koma, S. Paessler, 2020, Journal of Virology.

Absence of an N-Linked Glycosylation Motif in the Glycoprotein of the Live-Attenuated Argentine Hemorrhagic Fever Vaccine, Candid #1, Results in Its Improper Processing, and Reduced Surface Expression

J. C. de la Torre, J. Barral, T. Koma, 2017, Front. Cell. Infect. Microbiol..

Junín Virus Infection Activates the Type I Interferon Pathway in a RIG-I-Dependent Manner

O. Kolokoltsova, A. Brasier, B. Tian, 2012, PLoS neglected tropical diseases.

Differences in Tissue and Species Tropism of Reptarenavirus Species Studied by Vesicular Stomatitis Virus Pseudotypes

J. Hepojoki, A. Kipar, O. Vapalahti, 2020, Viruses.

Molecular and Cell Biology of the Prototypic Arenavirus LCMV: Implications for Understanding and Combating Hemorrhagic Fever Arenaviruses

J. C. de la Torre, 2009, Annals of the New York Academy of Sciences.

Arenaviruses: genomic RNAs, transcription, and replication.

B. Meyer, J. C. de la Torre, P. Southern, 2002, Current topics in microbiology and immunology.

Expression of tissue factor is increased in astrocytes within the central nervous system during persistent infection with borna disease virus

N. Mackman, D. Gonzalez-Dunia, J. C. de la Torre, 1996, Journal of virology.

Virus-induced immunosuppression: kinetic analysis of the selection of a mutation associated with viral persistence

P. Borrow, J. C. de la Torre, M. Oldstone, 1994, Journal of virology.

Identification of Inhibitors of ZIKV Replication

F. Almazán, J. C. de la Torre, A. Nogales, 2020, Viruses.

A Methionine-Rich Domain Mediates CRM1-Dependent Nuclear Export Activity of Borna Disease Virus Phosphoprotein

K. Ikuta, H. Yanai, Guoqi Zhang, 2006, Journal of Virology.

Use of Single-Cycle Infectious Lymphocytic Choriomeningitis Virus To Study Hemorrhagic Fever Arenaviruses

J. C. de la Torre, L. Martínez-Sobrido, W. W. S. I. Rodrigo, 2010, Journal of Virology.

The Z Protein of the New World Arenavirus Tacaribe Virus Has Bona Fide Budding Activity That Does Not Depend on Known Late Domain Motifs

J. C. de la Torre, J. Yasuda, Shuzo Urata, 2009, Journal of Virology.

A Highly Conserved Leucine in Mammarenavirus Matrix Z Protein Is Required for Z Interaction with the Virus L Polymerase and Z Stability in Cells Harboring an Active Viral Ribonucleoprotein

J. C. de la Torre, Masaharu Iwasaki, 2018, Journal of Virology.

Interactome analysis of the lymphocytic choriomeningitis virus nucleoprotein in infected cells reveals ATPase Na+/K+ transporting subunit Alpha 1 and prohibitin as host-cell factors involved in the life cycle of mammarenaviruses

J. Yates, B. Torbett, J. Kuhn, 2018, PLoS pathogens.

Lassa Virus Reverse Genetics.

J. C. de la Torre, L. Martínez-Sobrido, S. Paessler, 2017, Methods in molecular biology.

Resistance of human plasmacytoid dendritic CAL-1 cells to infection with lymphocytic choriomeningitis virus (LCMV) is caused by restricted virus cell entry, which is overcome by contact of CAL-1 cells with LCMV-infected cells.

J. C. de la Torre, Masaharu Iwasaki, Brett S. Marro, 2017, Virology.

Transcription and replication mechanisms of Bunyaviridae and Arenaviridae L proteins

F. Weber, J. Reguera, J. C. de la Torre, 2017, Virus Research.

The High Degree of Sequence Plasticity of the Arenavirus Noncoding Intergenic Region (IGR) Enables the Use of a Nonviral Universal Synthetic IGR To Attenuate Arenaviruses

J. C. de la Torre, Masaharu Iwasaki, B. Cubitt, 2016, Journal of Virology.

Reporter-Expressing, Replicating-Competent Recombinant Arenaviruses

J. C. de la Torre, L. Martínez-Sobrido, 2016, Viruses.

Reverse Genetics Approaches to Control Arenavirus.

J. C. de la Torre, L. Martínez-Sobrido, B. Cheng, 2016, Methods in molecular biology.

Efficient Interaction between Arenavirus Nucleoprotein (NP) and RNA-Dependent RNA Polymerase (L) Is Mediated by the Virus Nucleocapsid (NP-RNA) Template

J. C. de la Torre, Masaharu Iwasaki, B. Cubitt, 2015, Journal of Virology.

General Molecular Strategy for Development of Arenavirus Live-Attenuated Vaccines

J. C. de la Torre, J. Teijaro, Masaharu Iwasaki, 2015, Journal of Virology.

Arenavirus Genome Rearrangement for the Development of Live Attenuated Vaccines

J. C. de la Torre, L. Martínez-Sobrido, Emilio Ortiz-Riaño, 2015, Journal of Virology.

Generation of recombinant arenavirus for vaccine development in FDA-approved Vero cells.

J. C. de la Torre, L. Martínez-Sobrido, Emilio Ortiz-Riaño, 2013, Journal of visualized experiments : JoVE.

Ribavirin Can Be Mutagenic for Arenaviruses

E. Domingo, J. C. de la Torre, V. Martín, 2011, Journal of Virology.

The C-Terminal Region of Lymphocytic Choriomeningitis Virus Nucleoprotein Contains Distinct and Segregable Functional Domains Involved in NP-Z Interaction and Counteraction of the Type I Interferon Response

J. C. de la Torre, L. Martínez-Sobrido, Emilio Ortiz-Riaño, 2011, Journal of Virology.

Conserved Residues in Lassa Fever Virus Z Protein Modulate Viral Infectivity at the Level of the Ribonucleoprotein

M. Buchmeier, J. C. de la Torre, Althea A. Capul, 2011, Journal of Virology.

Targeting the Proteolytic Processing of the Viral Glycoprotein Precursor Is a Promising Novel Antiviral Strategy against Arenaviruses

S. Kunz, Jillian M. Rojek, Ana B. Sánchez, 2009, Journal of Virology.

Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest

D. McGavern, J. C. de la Torre, L. Garidou, 2009, Proceedings of the National Academy of Sciences.

Differential Inhibition of Type I Interferon Induction by Arenavirus Nucleoproteins

A. García-Sastre, J. C. de la Torre, L. Martínez-Sobrido, 2007, Journal of Virology.

Taxonomy of the order Bunyavirales: update 2019

X. de Lamballerie, R. Charrel, J. Gonzalez, 2019, Archives of Virology.

Identification and Mechanism of Action of a Novel Small-Molecule Inhibitor of Arenavirus Multiplication

J. C. de la Torre, Masaharu Iwasaki, B. Cubitt, 2015, Journal of Virology.

Role of the Host Cell's Unfolded Protein Response in Arenavirus Infection

S. Kunz, A. Pasquato, J. C. de la Torre, 2010, Journal of Virology.

Evaluation of the anti-arenaviral activity of the subtilisin kexin isozyme-1/site-1 protease inhibitor PF-429242.

S. Kunz, A. Pasquato, J. C. de la Torre, 2012, Virology.

Taxonomy of the family Arenaviridae and the order Bunyavirales: update 2018

E. Koonin, Y. Wolf, J. Derisi, 2018, Archives of Virology.

Development of Reverse Genetics for the Prototype New World Mammarenavirus Tacaribe Virus

J. C. de la Torre, L. Martínez-Sobrido, C. Ye, 2020, Journal of Virology.

Rescue of the prototypic Arenavirus LCMV entirely from plasmid.

Ana B. Sánchez, J. C. de la Torre, 2006, Virology.

Dual Role of the Lymphocytic Choriomeningitis Virus Intergenic Region in Transcription Termination and Virus Propagation

J. C. de la Torre, Mar Perez, D. Pinschewer, 2005, Journal of Virology.

Recovery of an arenavirus entirely from RNA polymerase I/II-driven cDNA.

A. Bergthaler, J. C. de la Torre, D. Pinschewer, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Persistence of Lassa Virus Associated With Severe Systemic Arteritis in Convalescing Guinea Pigs (Cavia porcellus)

J. Kuhn, P. Jahrling, Yíngyún Caì, 2018, Journal of Infectious Diseases.

A Lassa Virus Live-Attenuated Vaccine Candidate Based on Rearrangement of the Intergenic Region

M. St. Claire, J. Kuhn, E. Postnikova, 2020, mBio.

Role of the Virus Nucleoprotein in the Regulation of Lymphocytic Choriomeningitis Virus Transcription and RNA Replication

J. C. de la Torre, Mar Perez, D. Pinschewer, 2003, Journal of Virology.

A single mutation (V64G) within the RING Domain of Z attenuates Junin virus

S. Hallam, J. C. de la Torre, Junki Maruyama, 2020, PLoS neglected tropical diseases.

The Glycoprotein Precursor Gene of Junin Virus Determines the Virulence of the Romero Strain and the Attenuation of the Candid #1 Strain in a Representative Animal Model of Argentine Hemorrhagic Fever

J. C. de la Torre, S. Paessler, Jennifer K. Smith, 2015, Journal of Virology.

Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling.

Sonya P Lad, Erguang Li, T. Chao, 2008, Molecular immunology.

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales.

John S. Hu, Steven B. Bradfute, E. Koonin, 2021, Archives of virology.

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

Steven B. Bradfute, E. Koonin, Y. Wolf, 2020, Archives of Virology.

A cell-based luciferase assay amenable to high-throughput screening of inhibitors of arenavirus budding.

J. C. de la Torre, Althea A. Capul, 2008, Virology.

Lassa Virus Vaccine Candidate ML29 Generates Truncated Viral RNAs Which Contribute to Interfering Activity and Attenuation

I. Lukashevich, J. C. de la Torre, B. Cubitt, 2021, Viruses.

Very high frequency of reversion to guanidine resistance in clonal pools of guanidine-dependent type 1 poliovirus

E. Domingo, J. Holland, E. Wimmer, 1990, Journal of virology.

High nucleotide substitution error frequencies in clonal pools of vesicular stomatitis virus

J. Holland, D. Steinhauer, L. De, 1989, Journal of virology.

Ribavirin cures cells of a persistent infection with foot-and-mouth disease virus in vitro

E. Domingo, Luis Carrasco, E. Martínez-Salas, 1987, Journal of virology.

Lassa virus diversity and feasibility for universal prophylactic vaccine

I. Lukashevich, J. C. de la Torre, S. Paessler, 2019, F1000Research.

Cells Expressing the RING Finger Z Protein Are Resistant to Arenavirus Infection

H. Feldmann, J. C. de la Torre, T. Cornu, 2004, Journal of Virology.

Rescue from Cloned cDNAs and In Vivo Characterization of Recombinant Pathogenic Romero and Live-Attenuated Candid #1 Strains of Junin Virus, the Causative Agent of Argentine Hemorrhagic Fever Disease

J. C. de la Torre, S. Paessler, A. Poussard, 2010, Journal of Virology.

Recombinant lymphocytic choriomeningitis virus expressing vesicular stomatitis virus glycoprotein

Ana B. Sánchez, J. C. de la Torre, Mar Perez, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Reverse genetics of arenaviruses.

J. C. de la Torre, K. J. Lee, 2002, Current topics in microbiology and immunology.

T-705 (Favipiravir) Inhibition of Arenavirus Replication in Cell Culture

D. Smee, J. Nunberg, J. C. de la Torre, 2010, Antimicrobial Agents and Chemotherapy.

Novel Dihydroorotate Dehydrogenase Inhibitors with Potent Interferon-Independent Antiviral Activity against Mammarenaviruses In Vitro

J. Kuhn, Yíngyún Caì, J. C. de la Torre, 2020, Viruses.

ICTV Virus Taxonomy Profile: Arenaviridae.

R. Charrel, J. Gonzalez, M. Buchmeier, 2019, The Journal of general virology.

Molecular biology of Borna disease virus and persistence.

J. C. de la Torre, 2002, Frontiers in bioscience : a journal and virtual library.

Characterization of Borna disease virus p56 protein, a surface glycoprotein involved in virus entry

L. De, D. Gonzalez-Dunia, J. C. de la Torre, 1997, Journal of virology.

Increased Immune Response Variability during Simultaneous Viral Coinfection Leads to Unpredictability in CD8 T Cell Immunity and Pathogenesis

J. C. de la Torre, M. Cornberg, L. Selin, 2015, Journal of Virology.

Molecular biology of borna disease virus: prototype of a new group of animal viruses

J. C. de la Torre, 1994, Journal of virology.

Taxonomy of the order Bunyavirales: second update 2018

J. Derisi, X. de Lamballerie, R. Charrel, 2019, Archives of Virology.

Kinetics of protective antibodies are determined by the viral surface antigen.

R. Zinkernagel, T. Bächi, M. Whitt, 2004, The Journal of clinical investigation.

Algorithms for testing COVID-19 focused on use of RT-PCR and high-affinity serological testing: A consensus statement from a panel of Latin American experts

J. C. de la Torre, A. Condino-Neto, P. Bonvehi, 2020, International Journal of Infectious Diseases.

Human Pathogenic Arenaviruses (Arenaviridae)

S. Radoshitzky, J. C. de la Torre, 2020, Reference Module in Life Sciences.

The chameleonic genetics of Lassa virus.

M. Sironi, J. C. de la Torre, 2019, The Lancet. Infectious diseases.

Dimethyl Fumarate Disrupts Human Innate Immune Signaling by Targeting the IRAK4–MyD88 Complex

J. Casanova, B. Cravatt, Daniel C. Lazar, 2019, The Journal of Immunology.

Borna Disease Virus Persistence Causes Inhibition of Glutamate Uptake by Feline Primary Cortical Astrocytes

J. C. de la Torre, J. Billaud, T. Phillips, 2000, Journal of Virology.

Virus-like particles in MDCK cells persistently infected with Borna disease virus

R. Compans, J. C. de la Torre, L. R. Melsen, 1994, Virus Research.

Human Plasmacytoid Dendritic Cells Sense Lymphocytic Choriomeningitis Virus-Infected Cells In Vitro

F. Chisari, S. Wieland, J. C. de la Torre, 2013, Journal of Virology.

Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses

G. Cheng, R. Damoiseaux, J. Colicelli, 2013, Proceedings of the National Academy of Sciences.

Inhibitors of Anti-apoptotic Bcl-2 Family Proteins Exhibit Potent and Broad-Spectrum Anti-mammarenavirus Activity via Cell Cycle Arrest at G0/G1 Phase

J. C. de la Torre, B. Cubitt, Yu-Jin Kim, 2021, Journal of virology.

Inhibitors of anti-apoptotic Bcl-2 family proteins exhibit potent and broad-spectrum anti-mammarenavirus activity via cell cycle arrest at G0/G1 phase

J. C. de la Torre, B. Cubitt, Yu-Jin Kim, 2021, bioRxiv.

1-β-d-Arabinofuranosylcytosine Inhibits Borna Disease Virus Replication and Spread

D. Gonzalez-Dunia, J. C. de la Torre, M. Brahic, 2002, Journal of Virology.

RING Finger Z Protein of Lymphocytic Choriomeningitis Virus (LCMV) Inhibits Transcription and RNA Replication of an LCMV S-Segment Minigenome

J. C. de la Torre, T. Cornu, 2001, Journal of Virology.

Molecular characterization of the Borna disease agent.

W. Lipkin, J. C. de la Torre, K. Carbone, 1990, Virology.

Residues K465 and G467 within the Cytoplasmic Domain of GP2 Play a Critical Role in the Persistence of Lymphocytic Choriomeningitis Virus in Mice

C. Ng, J. C. de la Torre, Masaharu Iwasaki, 2016, Journal of Virology.

Lymphocytic Choriomeningitis Virus Differentially Affects the Virus-Induced Type I Interferon Response and Mitochondrial Apoptosis Mediated by RIG-I/MAVS

S. Kunz, J. C. de la Torre, L. Martínez-Sobrido, 2015, Journal of Virology.

Mice Lacking Functional STAT1 Are Highly Susceptible to Lethal Infection with Lassa Virus

N. Wauquier, J. C. de la Torre, V. Popov, 2013, Journal of Virology.

Arenavirus Z-Glycoprotein Association Requires Z Myristoylation but Not Functional RING or Late Domains

M. Buchmeier, S. Kunz, J. C. de la Torre, 2007, Journal of Virology.

Identification of the Lymphocytic Choriomeningitis Virus (LCMV) Proteins Required To Rescue LCMV RNA Analogs into LCMV-Like Particles

J. C. de la Torre, Mar Perez, D. Pinschewer, 2002, Journal of Virology.

Loss of Anti-Viral Immunity by Infection with a Virus Encoding a Cross-Reactive Pathogenic Epitope

J. Rossjohn, S. Gras, J. C. de la Torre, 2012, PLoS pathogens.

Sequence and genome organization of Borna disease virus

L. De, J. C. de la Torre, B. Cubitt, 1994, Journal of virology.

RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis

C. Samuel, C. George, J. C. de la Torre, 2010, Proceedings of the National Academy of Sciences.

Bornavirus and the brain.

J. C. de la Torre, 2002, The Journal of infectious diseases.

Early Virus-Host Interactions Dictate the Course of a Persistent Infection

J. C. de la Torre, M. Oldstone, J. Teijaro, 2015, PLoS pathogens.

The Pan-ErbB tyrosine kinase inhibitor afatinib inhibits multiple steps of the mammarenavirus life cycle.

J. C. de la Torre, Masaharu Iwasaki, B. Cubitt, 2022, Virology.

Viral persistence in neurons alters synaptic plasticity and cognitive functions without destruction of brain cells.

E. Masliah, M. Mallory, G. Koob, 1996, Virology.

BST-2 controls T cell proliferation and exhaustion by shaping the early distribution of a persistent viral infection

D. Nayak, D. McGavern, J. C. de la Torre, 2018, PLoS pathogens.

A reverse genetics system for Borna disease virus.

Ana B. Sánchez, J. C. de la Torre, Mar Perez, 2003, The Journal of general virology.

Borna disease virus (BDV), a nonsegmented RNA virus, replicates in the nuclei of infected cells where infectious BDV ribonucleoproteins are present

J. C. de la Torre, B. Cubitt, J. C. D. L. Torre, 1994, Journal of virology.

Development of Recombinant Arenavirus-Based Vaccines.

J. C. de la Torre, L. Martínez-Sobrido, 2017, Methods in molecular biology.

Type I interferon is a therapeutic target for virus-induced lethal vascular damage

C. Ng, A. Theofilopoulos, J. C. de la Torre, 2014, Proceedings of the National Academy of Sciences.

Viral persistence and disease: cytopathology in the absence of cytolysis.

P. Borrow, J. C. de la Torre, M. Oldstone, 1991, British medical bulletin.

Borna disease virus, a negative-strand RNA virus, transcribes in the nucleus of infected cells.

T. Briese, W. Lipkin, J. C. de la Torre, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Cell-to-Cell Spread of Borna Disease Virus Proceeds in the Absence of the Virus Primary Receptor and Furin-Mediated Processing of the Virus Surface Glycoprotein

J. C. de la Torre, Roberto Clemente, 2007, Journal of Virology.

Resistance to foot-and-mouth disease virus mediated by trans-acting cellular products

E. Domingo, S. de la Luna, J. C. de la Torre, 1989, Journal of virology.

Analysis of SARS-CoV-2 infection dynamic in vivo using reporter-expressing viruses

R. Plemper, Julien Sourimant, J. C. de la Torre, 2021, Proceedings of the National Academy of Sciences.

Experimental reproduction of severe hypoglycemia and spiking mortality syndrome using field-derived and embryo-passaged preparations.

J. C. de la Torre, A. Castro, H. Lu, 1996, Avian diseases.

Inhibition of the Type I Interferon Response by the Nucleoprotein of the Prototypic Arenavirus Lymphocytic Choriomeningitis Virus

A. García-Sastre, E. Zúñiga, J. C. de la Torre, 2006, Journal of Virology.

Arenavirus genetic diversity and its biological implications

E. Domingo, J. C. de la Torre, N. Sevilla, 2009, Infection, Genetics and Evolution.

Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

John S. Hu, Steven B. Bradfute, E. Koonin, 2021, Archives of Virology.

Hypoglycemia, enteritis, and spiking mortality in Georgia broiler chickens: experimental reproduction in broiler breeder chicks.

C. Scanes, J. C. de la Torre, A. Castro, 1995, Avian diseases.

A Bifluorescent-Based Assay for the Identification of Neutralizing Antibodies against SARS-CoV-2 Variants of Concern In Vitro and In Vivo

R. Plemper, Julien Sourimant, M. Piepenbrink, 2021, bioRxiv.

Development of a high-throughput homogeneous AlphaLISA drug screening assay for the detection of SARS-CoV-2 Nucleocapsid

Catherine Z. Chen, Wei Zheng, J. C. de la Torre, 2020, bioRxiv.

Coevolution of cells and viruses in a persistent infection of foot-and-mouth disease virus in cell culture

E. Domingo, F. Gebauer, A. Villaverde, 1988, Journal of virology.

Rapid selection of genetic and antigenic variants of foot-and-mouth disease virus during persistence in cattle

E. Domingo, F. Gebauer, M. G. Mateu, 1988, Journal of virology.

N-Terminal Domain of Borna Disease Virus G (p56) Protein Is Sufficient for Virus Receptor Recognition and Cell Entry

M. Whitt, J. C. de la Torre, Mar Perez, 2001, Journal of Virology.

Type I and Type II Interferon Coordinately Regulate Suppressive Dendritic Cell Fate and Function during Viral Persistence

S. Smale, M. Horwitz, J. C. de la Torre, 2016, PLoS pathogens.

Virus mutation frequencies can be greatly underestimated by monoclonal antibody neutralization of virions

E. Domingo, J. Holland, D. Steinhauer, 1989, Journal of virology.

Establishment of cell lines persistently infected with foot-and-mouth disease virus.

E. Domingo, F. Sobrino, J. C. de la Torre, 1985, Virology.

Identification of Amino Acid Residues Critical for the Anti-Interferon Activity of the Nucleoprotein of the Prototypic Arenavirus Lymphocytic Choriomeningitis Virus

A. García-Sastre, J. C. de la Torre, L. Martínez-Sobrido, 2009, Journal of Virology.

Inhibition of Arenavirus by A3, a Pyrimidine Biosynthesis Inhibitor

M. Shaw, J. C. de la Torre, D. Eggink, 2013, Journal of Virology.

Reverse genetics approaches to combat pathogenic arenaviruses

J. C. de la Torre, 2008, Antiviral Research.

Identification and Characterization of Novel Compounds with Broad-Spectrum Antiviral Activity against Influenza A and B Viruses

J. C. de la Torre, A. Nogales, L. Martínez-Sobrido, 2020, Journal of Virology.

Inhibition of multiplication of the prototypic arenavirus LCMV by valproic acid.

J. Saiz, M. Martín-Acebes, F. Sobrino, 2013, Antiviral research.

RNA Interference-Mediated Virus Clearance from Cells both Acutely and Chronically Infected with the Prototypic Arenavirus Lymphocytic Choriomeningitis Virus

Ana B. Sánchez, J. C. de la Torre, Mar Perez, 2005, Journal of Virology.

The small RING finger protein Z drives arenavirus budding: Implications for antiviral strategies

J. C. de la Torre, Mar Perez, R. Craven, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Suppression of Fcγ-receptor-mediated antibody effector function during persistent viral infection.

S. Morrison, J. C. de la Torre, D. Brooks, 2015, Immunity.

Inhibition of the Type I Interferon Antiviral Response During Arenavirus Infection

P. Borrow, J. C. de la Torre, L. Martínez-Sobrido, 2010, Viruses.

Immunosuppression and Resultant Viral Persistence by Specific Viral Targeting of Dendritic Cells

Andreas Holz, Dirk Homann, K. Campbell, 2000, The Journal of experimental medicine.

PLD3 and PLD4 are single stranded acid exonucleases that regulate endosomal nucleic acid sensing

B. Cravatt, D. Nemazee, Meredith O'Keeffe, 2018, Nature Immunology.

Sodium Hydrogen Exchangers Contribute to Arenavirus Cell Entry

J. C. de la Torre, Masaharu Iwasaki, N. Ngo, 2013, Journal of Virology.

Myristoylation of the RING Finger Z Protein Is Essential for Arenavirus Budding

J. C. de la Torre, Mar Perez, Dori L Greenwald, 2004, Journal of Virology.

Characterization of the Genomic Promoter of the Prototypic Arenavirus Lymphocytic Choriomeningitis Virus

J. C. de la Torre, Mar Perez, 2003, Journal of Virology.

2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

David G. Karlin, Steven B. Bradfute, E. Koonin, 2022, Archives of virology.

Type I interferon suppresses virus-specific B cell responses by modulating CD8+ T cell differentiation

P. Schwartzberg, D. McGavern, J. C. de la Torre, 2016, Science Immunology.

Taxonomy of the order Bunyavirales: update 2019

R. Charrel, J. Gonzalez, A. Lambert, 2019, Archives of Virology.

Identification of Host Factors Involved in Borna Disease Virus Cell Entry through a Small Interfering RNA Functional Genetic Screen

P. Aza-Blanc, J. C. de la Torre, Roberto Clemente, 2010, Journal of Virology.

Cell Entry of Borna Disease Virus Follows a Clathrin-Mediated Endocytosis Pathway That Requires Rab5 and Microtubules

J. C. de la Torre, Juan C. de la Torre, Roberto Clemente, 2009, Journal of Virology.

Identification of the Borna disease virus (BDV) proteins required for the formation of BDV-like particles.

J. C. de la Torre, Mar Perez, 2005, The Journal of general virology.

Functional Characterization of the Genomic Promoter of Borna Disease Virus (BDV): Implications of 3′-Terminal Sequence Heterogeneity for BDV Persistence

J. C. de la Torre, Mar Perez, D. Rosario, 2005, Journal of Virology.

Identification and characterization of a new intron in Borna disease virus.

J. C. de la Torre, B. Cubitt, C. Ly, 2001, The Journal of general virology.

Sensitivity and reproducibility of RT-PCR to detect Borna disease virus (BDV) RNA in blood: implications for BDV epidemiology.

J. C. de la Torre, C. Sauder, 1998, Journal of virological methods.

Mechanism of Borna Disease Virus Entry into Cells

D. Gonzalez-Dunia, J. C. de la Torre, B. Cubitt, 1998, Journal of Virology.

Detection of Borna disease virus (BDV) antibodies and BDV RNA in psychiatric patients: evidence for high sequence conservation of human blood-derived BDV RNA

L. De, J. C. de la Torre, F. Grässer, 1996, Journal of virology.

Sequence characterization of human Borna disease virus.

J. C. de la Torre, R. Dürrwald, B. Cubitt, 1996, Virus research.

Molecular biology of Borna disease virus.

T. Briese, W. Lipkin, J. C. de la Torre, 1995, Current topics in microbiology and immunology.

Borna disease virus: molecular analysis of a neurotropic infectious agent.

T. Briese, W. Lipkin, J. C. de la Torre, 1992, Microbial pathogenesis.

Isolation of Borna Disease Virus from Human Brain Tissue

K. Ikuta, K. Tomonaga, Y. Shoya, 2000, Journal of Virology.

Borna Disease Virus and the Brain

D. Gonzalez-Dunia, J. C. de la Torre, C. Sauder, 1997, Brain Research Bulletin.

Anatomy of viral persistence: mechanisms of persistence and associated disease.

J. C. de la Torre, M. Oldstone, Michael B. A. Oldstone, 1996, Advances in virus research.

Development of live-attenuated arenavirus vaccines based on codon deoptimization of the viral glycoprotein.

J. C. de la Torre, A. Nogales, L. Martínez-Sobrido, 2017, Virology.

DDX3 suppresses type I interferons and favors viral replication during Arenavirus infection

S. Radoshitzky, S. Dallari, E. Zúñiga, 2018, PLoS pathogens.

Proximity interactome analysis of Lassa polymerase reveals eRF3a/GSPT1 as a druggable target for host-directed antivirals

E. Saphire, A. Ting, J. C. de la Torre, 2021, bioRxiv.

Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits

Pardis C Sabeti, Donald S. Grant, Mohamed A. Vandi, 2016, Nature Communications.

A Lassa Fever Live-Attenuated Vaccine Based on Codon Deoptimization of the Viral Glycoprotein Gene

M. St. Claire, J. Kuhn, E. Postnikova, 2020, mBio.

Novel strategies for development of hemorrhagic fever arenavirus live-attenuated vaccines

J. C. de la Torre, L. Martínez-Sobrido, 2016, Expert review of vaccines.

Recombinant Lassa Virus Expressing Green Fluorescent Protein as a Tool for High-Throughput Drug Screens and Neutralizing Antibody Assays

J. Kuhn, E. Postnikova, S. Radoshitzky, 2018, Viruses.

Arenavirus Quasispecies and Their Biological Implications

J. C. de la Torre, V. Martín, A. Grande-Pérez, 2015, Current topics in microbiology and immunology.

Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E

K. Borden, J. C. de la Torre, M. J. Osborne, 2010, Proceedings of the National Academy of Sciences.

Expansion of CD8+ T cell population in Lassa virus survivors with low T cell precursor frequency reveals durable immune response in most survivors

R. Garry, J. C. de la Torre, M. Oldstone, 2022, PLoS neglected tropical diseases.

High crossreactivity of human T cell responses between Lassa virus lineages

Pardis C Sabeti, Brian C. Ware, Brian C Ware, 2020, PLoS pathogens.

Novel antiviral strategies to combat human Arenavirus infections.

S. Kunz, J. C. de la Torre, 2005, Current molecular medicine.

Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV).

E. Domingo, C. M. Ruiz-Jarabo, J. C. de la Torre, 2003, Virology.

A single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with the ability to cause growth hormone deficiency syndrome

P. Borrow, J. C. de la Torre, M. Oldstone, 1996, Journal of virology.

Arenavirus Nucleoproteins Prevent Activation of Nuclear Factor Kappa B

S. Kunz, J. C. de la Torre, L. Martínez-Sobrido, 2012, Journal of Virology.

Progress in Anti-Mammarenavirus Drug Development

J. C. de la Torre, Yu-Jin Kim, Victor Venturini, 2021, Viruses.

Taxonomy of the family Arenaviridae and the order Bunyavirales: update 2018

E. Koonin, Y. Wolf, J. Derisi, 2018, Archives of Virology.

A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity

Catherine Z. Chen, Noel Southall, Wei Zheng, 2019, Antiviral Research.

Molecular Engineering of a Mammarenavirus with Unbreachable Attenuation

J. C. de la Torre, L. Martínez-Sobrido, B. Cubitt, 2022, Journal of virology.

Detection of borna disease virus antigen and RNA in human autopsy brain samples from neuropsychiatric patients.

E. Masliah, M. Mallory, L. Hansen, 1996, Virology.

Point mutation in the glycoprotein of lymphocytic choriomeningitis virus is necessary for receptor binding, dendritic cell infection, and long-term persistence

K. Campbell, J. C. de la Torre, M. Oldstone, 2011, Proceedings of the National Academy of Sciences.

Mapping the Landscape of the Lymphocytic Choriomeningitis Virus Stable Signal Peptide Reveals Novel Functional Domains

B. Neuman, M. Buchmeier, J. Ting, 2007, Journal of Virology.

Mechanisms for lymphocytic choriomeningitis virus glycoprotein cleavage, transport, and incorporation into virions.

S. Kunz, J. C. de la Torre, M. Oldstone, 2003, Virology.

The Ebola virus glycoprotein mediates entry via a non-classical dynamin-dependent macropinocytic pathway.

M. Raaben, N. Mulherkar, S. Whelan, 2011, Virology.

Arenavirus reverse genetics: New approaches for the investigation of arenavirus biology and development of antiviral strategies

J. C. de la Torre, Shuzo Urata, S. Emonet, 2011, Virology.

Molecular mimicry accompanying HIV-1 infection: human monoclonal antibodies that bind to gp41 and to astrocytes.

S. Zolla-Pazner, J. C. de la Torre, M. Oldstone, 1993, AIDS research and human retroviruses.

The PI3K/Akt Pathway Contributes to Arenavirus Budding

J. C. de la Torre, N. Ngo, Shuzo Urata, 2012, Journal of Virology.

Crystal structure of the Lassa virus nucleoprotein–RNA complex reveals a gating mechanism for RNA binding

Virgil L. Woods, E. Saphire, Sheng Li, 2011, Proceedings of the National Academy of Sciences.

Arenavirus Budding

J. C. de la Torre, Shuzo Urata, 2011, Advances in virology.

Chaperonin TRiC/CCT Participates in Mammarenavirus Multiplication in Human Cells via Interaction with the Viral Nucleoprotein

J. C. de la Torre, B. Cubitt, Saori Sakabe, 2023, Journal of virology.

Disruption of differentiated functions during viral infection in vivo. V. Mapping of a locus involved in susceptibility of mice to growth hormone deficiency due to persistent lymphocytic choriomeningitis virus infection.

S. Le Goff, J. C. de la Torre, M. Oldstone, 2001, Virology.

Development of Live-Attenuated Arenavirus Vaccines Based on Codon Deoptimization

J. C. de la Torre, A. Nogales, L. Martínez-Sobrido, 2015, Journal of Virology.

Rescue of SARS-CoV-2 from a single bacterial artificial chromosome

F. Almazán, R. N. Platt, T. Anderson, 2020, bioRxiv.

Envelope Exchange for the Generation of Live-Attenuated Arenavirus Vaccines

A. Bergthaler, J. C. de la Torre, D. Merkler, 2006, PLoS pathogens.

Characterization of the Arenavirus RING Finger Z Protein Regions Required for Z-Mediated Inhibition of Viral RNA Synthesis

J. C. de la Torre, T. Cornu, 2002, Journal of Virology.

Human LAMP1 accelerates Lassa virus fusion and potently promotes fusion pore dilation upon forcing viral fusion with non-endosomal membrane

G. Melikyan, J. C. de la Torre, You Zhang, 2022, bioRxiv.

Genomic and biological characterization of aggressive and docile strains of lymphocytic choriomeningitis virus rescued from a plasmid-based reverse-genetics system.

D. Moskophidis, J. C. de la Torre, Hong Jiang, 2008, The Journal of general virology.

DDX3 is exploited by Arenaviruses to suppress type I interferons and favor their replication

S. Radoshitzky, S. Dallari, E. Zúñiga, 2017, bioRxiv.

Contribution of LCMV towards deciphering biology of quasispecies in vivo.

E. Domingo, J. C. de la Torre, N. Sevilla, 2002, Current topics in microbiology and immunology.

Extreme heterogeneity in populations of vesicular stomatitis virus

J. Holland, P. Ahlquist, D. Steinhauer, 1989, Journal of virology.

The ReFRAME library as a comprehensive drug repurposing library to identify mammarenavirus inhibitors.

J. Kuhn, Yíngyún Caì, J. C. de la Torre, 2019, Antiviral research.

Mutagenesis-Mediated Virus Extinction: Virus-Dependent Effect of Viral Load on Sensitivity to Lethal Defection

E. Domingo, J. C. de la Torre, V. Martín, 2012, PloS one.

Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation

S. Lipton, M. Karin, W. Tourtellotte, 2021, Immunity.

Generation and Characterization of a Recombinant Vesicular Stomatitis Virus Expressing the Glycoprotein of Borna Disease Virus

C. Robison, M. Whitt, J. C. de la Torre, 2007, Journal of Virology.

RIG-I Enhanced Interferon Independent Apoptosis upon Junin Virus Infection

O. Kolokoltsova, A. Brasier, B. Tian, 2014, PloS one.

Alterations in neurotrophin and neurotrophin receptor gene expression patterns in the rat central nervous system following perinatal Borna disease virus infection.

J. Schulte‐Mönting, J. C. de la Torre, C. Sauder, 2000, Journal of neurovirology.

Breaking the Barrier: Host Cell Invasion by Lujo Virus.

S. Kunz, J. C. de la Torre, 2017, Cell host & microbe.

Inflammatory monocytes hinder antiviral B cell responses

K. Larimore, P. Greenberg, L. Sironi, 2016, Science Immunology.

The M22 antibody identifies highly activated reactive astrocytes responding to central nervous system disease

I. Campbell, J. C. de la Torre, M. Oldstone, 1996, Acta Neuropathologica.

Reverse genetics approaches for the development of mammarenavirus live-attenuated vaccines.

J. C. de la Torre, L. Martínez-Sobrido, C. Ye, 2020, Current opinion in virology.

A head-to-tail tandem organization of hsp70 genes in Trypanosoma cruzi.

C Alonso, J. M. Requena, J. C. de la Torre, 1988, Nucleic acids research.

Fixation of mutations in the viral genome during an outbreak of foot-and-mouth disease: heterogeneity and rate variations.

E. Domingo, F. Sobrino, J. C. de la Torre, 1986, Gene.

Viral persistent infection affects both transcriptional and posttranscriptional regulation of neuron-specific molecule GAP43.

W. Cao, J. C. de la Torre, M. Oldstone, 1997, Virology.

A SARS-CoV-2 nucleocapsid protein TR-FRET assay amenable to high-throughput screening

Catherine Z. Chen, Wei Zheng, J. C. de la Torre, 2021, bioRxiv.

Design, synthesis, and biological evaluation of a biyouyanagin compound library

D. Burton, K. Nicolaou, D. Nomura, 2011, Proceedings of the National Academy of Sciences.

D471G Mutation in LCMV-NP Affects its Ability to Self-associate and Results in a Dominant Negative Effect in Viral RNA Synthesis

J. C. de la Torre, L. Martínez-Sobrido, Emilio Ortiz-Riaño, 2012, Viruses.

Borna Disease Virus Requires Cholesterol in both Cellular Membrane and Viral Envelope for Efficient Cell Entry

J. C. de la Torre, Mar Perez, A. de Parseval, 2009, Journal of Virology.

Beyond Tethering the Viral Particles: Immunomodulatory Functions of Tetherin (BST-2).

D. Nayak, D. McGavern, J. C. de la Torre, 2019, DNA and cell biology.

Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner.

Daniel L. Popkin, B. Beutler, S. Kunz, 2011, Cell host & microbe.

Variants able to cause growth hormone deficiency syndrome are present within the disease-nil WE strain of lymphocytic choriomeningitis virus

J. C. de la Torre, M. Oldstone, M. Teng, 1996, Journal of virology.

Arenavirus Diversity and Evolution: Quasispecies In Vivo

J. C. de la Torre, N. Sevilla, 2006, Current topics in microbiology and immunology.

Rescue of SARS-CoV-2 from a Single Bacterial Artificial Chromosome

F. Almazán, T. Anderson, J. C. de la Torre, 2020, mBio.

Extensive cell heterogeneity during persistent infection with foot-and-mouth disease virus

E. Domingo, J. Díez, E. Martínez-Salas, 1989, Journal of virology.

Cytotoxic T lymphocytes cleanse viral gene products from individually infected neurons and lymphocytes in mice persistently infected with lymphocytic choriomeningitis virus.

J. C. de la Torre, M. Oldstone, M. Eddleston, 1993, Virology.

Expanded Potential for Recombinant Trisegmented Lymphocytic Choriomeningitis Viruses: Protein Production, Antibody Production, and In Vivo Assessment of Biological Function of Genes of Interest

Daniel L. Popkin, J. C. de la Torre, H. Lewicki, 2011, Journal of Virology.

Altered Central Nervous System Gene Expression Caused by Congenitally Acquired Persistent Infection with Lymphocytic Choriomeningitis Virus

A. Roberts, S. Kunz, Jillian M. Rojek, 2006, Journal of Virology.

Suppression of lymphocytic choriomeningitis virus--induced growth hormone deficiency syndrome by disease-negative virus variants.

J. C. de la Torre, M. Oldstone, M. Teng, 1996, Virology.

Behavioral effects of persistent lymphocytic choriomeningitis virus infection in mice.

L. Gold, G. Koob, J. C. de la Torre, 1994, Behavioral and neural biology.

Identification of In Vitro Inhibitors of Monkeypox Replication

Y. Xiang, M. Lorenzo, R. Blasco, 2023, Microbiology spectrum.

Antivirals against monkeypox infections

Y. Xiang, M. Lorenzo, R. Blasco, 2023, bioRxiv.

Chemokine Guidance of Central Memory T Cells Is Critical for Antiviral Recall Responses in Lymph Nodes

U. V. von Andrian, S. Henrickson, U. V. Andrian, 2012, Cell.

Mining a Kröhnke Pyridine Library for Anti-Arenavirus Activity.

K. Janda, J. C. de la Torre, B. Cubitt, 2018, ACS infectious diseases.

NESIM-RT: A real-time distributed spiking neural network simulator

Daniel J. Rosa-Gallardo, Fernando M. Quintana, J. C. de la Torre, 2023, SoftwareX.

Viral diseases of the next century.

J. C. de la Torre, M. Oldstone, 1994, Transactions of the American Clinical and Climatological Association.