R. Williamson

发表

Trafficking of prion proteins through a caveolae-mediated endosomal pathway

S. Prusiner, E. V. van Donselaar, D. Burton, 2003, The Journal of cell biology.

Antibody and virus: binding and neutralization.

D. Burton, P. Parren, R. Williamson, 2000, Virology.

Pathologic Prion Protein Infects Cells by Lipid-Raft Dependent Macropinocytosis

S. Dowdy, J. Wadia, R. Williamson, 2008, PloS one.

High Titers of Transmissible Spongiform Encephalopathy Infectivity Associated with Extremely Low Levels of PrPSc in Vivo*

Declan King, R. Williamson, J. Manson, 2007, Journal of Biological Chemistry.

Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc.

D. Burton, N. Kanu, J. Brockes, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Anti-DNA antibodies are a major component of the intrathecal B cell response in multiple sclerosis.

D. Burton, P. Parren, P. Sanna, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice

S. Prusiner, D. Burton, G. Legname, 2002, Nature Biotechnology.

Immobilized prion protein undergoes spontaneous rearrangement to a conformation having features in common with the infectious form

S. Prusiner, D. Burton, G. Legname, 2001, The EMBO journal.

Rapid Assay of Phage-Derived Recombinant Human Fabs As Bispecific Antibodies

F. Bloom, D. Burton, D. Altieri, 1995, Bio/Technology.

Molecular immunologic strategies to identify antigens and b-cell responses unique to multiple sclerosis.

D. Burton, D. Gilden, B. Kleinschmidt-DeMasters, 2001, Archives of neurology.

Copper refolding of prion protein.

D. Burton, M. Sy, P. Gambetti, 2000, Biochemical and biophysical research communications.

Non‐infectious aggregates of the prion protein react with several PrPSc‐directed antibodies

D. Harris, R. Chiesa, R. Williamson, 2008, Journal of neurochemistry.

Lack of Prion Infectivity in Fixed Heart Tissue from Patients with Creutzfeldt-Jakob Disease or Amyloid Heart Disease

R. Williamson, M. Oldstone, L. Solforosi, 2013, Journal of Virology.

Directed selection of recombinant human monoclonal antibodies to herpes simplex virus glycoproteins from phage display libraries.

D. Burton, R. Williamson, A. De Logu, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Cloning the Antibody Response in Humans with Chronic Inflammatory Disease: Immunopanning of Subacute Sclerosing Panencephalitis (SSPE) Brain Sections with Antibody Phage Libraries Prepared from SSPE Brain Enriches for Antibody Recognizing Measles Virus Antigens In Situ

D. Burton, D. Gilden, R. Williamson, 2000, Journal of Virology.

Antibodies produced by clonally expanded plasma cells in multiple sclerosis cerebrospinal fluid

D. Hafler, H. Lassmann, J. Bennett, 2009, Annals of neurology.

Copper induces conformational changes in the N-terminal part of cell-surface PrPC

S. Prusiner, D. Burton, E. Leclerc, 2006, Archives of Virology.

A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform.

F E Cohen, D R Burton, R A Houghten, 1997, Journal of molecular biology.

Molecular profile of a human monoclonal antibody Fab fragment specific for Epstein-Barr virus gp350/220 antigen.

D. Burton, R. Williamson, M. Clementi, 2001, Human immunology.

Transfer of Scrapie Prion Infectivity by Cell Contact in Culture

N. Kanu, J. Brockes, R. Williamson, 2002, Current Biology.

Cross-Linking Cellular Prion Protein Triggers Neuronal Apoptosis in Vivo

B. Volpe, E. Masliah, J. Criado, 2004, Science.

pFab-CMV, a single vector system for the rapid conversion of recombinant Fabs into whole IgG1 antibodies.

R. Rozenshteyn, D. Burton, P. Sanna, 1999, Immunotechnology : an international journal of immunological engineering.

Selective Incorporation of Polyanionic Molecules into Hamster Prions*

S. Supattapone, B. Harris, R. Williamson, 2007, Journal of Biological Chemistry.

Characterization of a Type-Common Human Recombinant Monoclonal Antibody to Herpes Simplex Virus with High Therapeutic Potential

R. Rozenshteyn, D. Burton, F. Ramiro-Ibañez, 1998, Journal of Clinical Microbiology.

Protection of nude mice by passive immunization with a type-common human recombinant monoclonal antibody against HSV.

D. Burton, R. Williamson, S. Straus, 1996, Virology.

Recombinant human Fab to glycoprotein D neutralizes infectivity and prevents cell-to-cell transmission of herpes simplex viruses 1 and 2 in vitro.

D. Burton, P. Sanna, R. Williamson, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Topically applied human recombinant monoclonal IgG1 antibody and its Fab and F(ab')2 fragments protect mice from vaginal transmission of HSV-2.

D. Burton, L. Zeitlin, R. Williamson, 1996, Virology.

Detection and typing of herpes simplex viruses by using recombinant immunoglobulin fragments produced in bacteria

D. Burton, G. Fadda, P. Cattani, 1997, Journal of clinical microbiology.

Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein.

D R Burton, H Serban, S. Prusiner, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries.

D R Burton, C. Barbas, D. Burton, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies

A. B. van 't Wout, J. McLellan, D. Roymans, 2018, PLoS pathogens.

Antibiotic-induced acceleration of type 1 diabetes alters maturation of innate intestinal immunity

Richard Bonneau, Dan Knights, Gabriel A Al-Ghalith, 2018, eLife.

Antibodies in human infectious disease

D. Burton, P. Parren, P. Poignard, 2000, Immunologic research.

Molecular profile of an antibody response to HIV-1 as probed by combinatorial libraries.

G R Pilkington, C. Barbas, N. Haigwood, 1993, Journal of molecular biology.

Expression of a human monoclonal anti-(rhesus D) Fab fragment in Escherichia coli with the use of bacteriophage lambda vectors.

D. Burton, R. Williamson, M. Persson, 1991, The Biochemical journal.

Protease-resistant Prion Protein Amplification Reconstituted with Partially Purified Substrates and Synthetic Polyanions*

S. Supattapone, R. Williamson, James C. Geoghegan, 2005, Journal of Biological Chemistry.

A Change in the Conformation of Prions Accompanies the Emergence of a New Prion Strain

S. Prusiner, D. Burton, S. DeArmond, 2002, Neuron.

Single-Cell Repertoire Analysis Demonstrates that Clonal Expansion Is a Prominent Feature of the B Cell Response in Multiple Sclerosis Cerebrospinal Fluid 1

D. Gilden, R. Williamson, G. Owens, 2003, The Journal of Immunology.

Strain‐specified relative conformational stability of the scrapie prion protein

F. Cohen, S. Prusiner, D. Burton, 2001, Protein science : a publication of the Protein Society.

Toward Molecular Dissection of PrPC-PrPSc Interactions*

R. Williamson, L. Solforosi, J. Cruite, 2007, Journal of Biological Chemistry.

Pathologic prion protein is specifically recognized in situ by a novel PrP conformational antibody

B. Ghetti, A. Gabrielli, F. Tagliavini, 2006, Neurobiology of Disease.

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

Pauline M. Rudd, Giuseppe Legname, Stanley B. Prusiner, 2001, Nature.

Recombinant human respiratory syncytial virus (RSV) monoclonal antibody Fab is effective therapeutically when introduced directly into the lungs of RSV-infected mice.

D R Burton, C. Barbas, D. Burton, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Mapping the Prion Protein Using Recombinant Antibodies

Clemencia Pinilla, Richard A. Houghten, Stanley B. Prusiner, 1998, Journal of Virology.

Antibodies as Therapeutic Agents for Prion Disease

S. Prusiner, D. Burton, D. Peretz, 2003 .

Probing the Conformation of the Prion Protein within a Single Amyloid Fibril Using a Novel Immunoconformational Assay*

N. Makarava, O. Bocharova, I. Baskakov, 2006, Journal of Biological Chemistry.

Copper has differential effect on prion protein with polymorphism of position 129.

D. Burton, S. Haswell, M. Sy, 2000, Biochemical and biophysical research communications.

Identifying Key Components of the PrPC-PrPSc Replicative Interface*

R. Williamson, L. Solforosi, J. Mastrianni, 2008, Journal of Biological Chemistry.

Conformation of PrP(C) on the cell surface as probed by antibodies.

S. Prusiner, D. Burton, G. Legname, 2003, Journal of molecular biology.

Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.

F. Cohen, R. Fletterick, S. Prusiner, 1999, Journal of molecular biology.

Calpain-dependent Endoproteolytic Cleavage of PrPSc Modulates Scrapie Prion Propagation*

G. Telling, R. Williamson, R. Guttmann, 2004, Journal of Biological Chemistry.

Cytosolic Prion Protein in Neurons

S. Prusiner, D. Burton, S. DeArmond, 2003, The Journal of Neuroscience.

Human Antibody Responses to Mature and Immature Forms of Viral Envelope in Respiratory Syncytial Virus Infection: Significance for Subunit Vaccines

D. Burton, R. Chanock, J. Crowe, 1999, Journal of Virology.

A Recombinant Human Monoclonal Antibody to Human Metapneumovirus Fusion Protein That Neutralizes Virus In Vitro and Is Effective Therapeutically In Vivo

D. Burton, J. Crowe, D. Wright, 2007, Journal of Virology.

Neutralizing Human Fab Fragments against Measles Virus Recovered by Phage Display

Paul W. H. I. Parren, Dennis R. Burton, D. Burton, 2002, Journal of Virology.

Broadly Neutralizing Human Monoclonal Antibody Exhibits In Vivo Ef fi cacy Against Both Human Metapneumovirus and Respiratory Syncytial Virus

Z. Chen, D. Burton, Reagan G. Cox, 2014 .

Author response: Antibiotic-induced acceleration of type 1 diabetes alters maturation of innate intestinal immunity

Benjamin M Hillmann, Robin R. Shields-Cutler, Richard Bonneau, 2018 .

Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation.

Andreas Plückthun, Dennis R Burton, R. M. Jones, 2006, Journal of molecular biology.

Combinatorial Phage Antibody Libraries

D. Burton, M. Zwick, R. Williamson, 2006 .

Comparative Analysis of the CD19+ and CD138+ Cell Antibody Repertoires in the Cerebrospinal Fluid of Patients with Multiple Sclerosis1

D. Gilden, R. Williamson, G. Owens, 2004, The Journal of Immunology.

Characteristics of immunity induced by viral antigen or conferred by antibody via different administration routes

D. Burton, H. Tsutsumi, R. Williamson, 2002, Clinical and experimental immunology.

Cloning the antibody response in humans with inflammatory CNS disease: isolation of measles virus-specific antibodies from phage display libraries of a subacute sclerosing panencephalitis brain

D. Burton, D. Gilden, R. Williamson, 1999, Journal of Neuroimmunology.

Trafficking of prion proteins through a caveolae-mediated endosomal pathway

S. Prusiner, D. Burton, S. DeArmond, 2003, The Journal of cell biology.

Use of recombinant human antibody fragments for detection of cytomegalovirus antigenemia

D. Burton, T. Lazzarotto, P. Sanna, 1997, Journal of Clinical Microbiology.

Lack of Prion Infectivity in Fixed Heart Tissue from Patients with Creutzfeldt-Jakob Disease or Amyloid Heart Disease

R. Williamson, M. Oldstone, L. Solforosi, 2013, Journal of Virology.