C. Tikellis

发表

Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: implications for diabetic renal disease.

Merlin C. Thomas, Merlin C Thomas, M. Cooper, 2006, Journal of the American Society of Nephrology : JASN.

Metabolic memory and diabetic nephropathy: potential role for epigenetic mechanisms

M. Cooper, A. El-Osta, C. Tikellis, 2010, Nature Reviews Nephrology.

Calcitonin receptor isoforms expressed in the developing rat kidney.

M. Cooper, C. Tikellis, L. Xuereb, 2003, Kidney international.

The arterial depressor response to chronic low-dose angiotensin II infusion in female rats is estrogen dependent.

Merlin C. Thomas, Merlin C Thomas, C. Tikellis, 2012, American journal of physiology. Regulatory, integrative and comparative physiology.

Genetic Ace2 Deficiency Accentuates Vascular Inflammation and Atherosclerosis in the ApoE Knockout Mouse

Merlin C. Thomas, Merlin C Thomas, M. Cooper, 2010, Circulation research.

Angiotensin-converting enzyme 2 is a key modulator of the renin–angiotensin system in cardiovascular and renal disease

W. Burns, C. Tikellis, S. Bernardi, 2011, Current opinion in nephrology and hypertension.

Myocardial infarction increases ACE2 expression in rat and humans.

P. Macdonald, C. Johnston, M. Cooper, 2005, European heart journal.

Transactivation of RAGE mediates angiotensin-induced inflammation and atherogenesis

Merlin C. Thomas, Merlin C Thomas, J. Golledge, 2018, The Journal of clinical investigation.

Improved islet morphology after blockade of the renin- angiotensin system in the ZDF rat.

Merlin C. Thomas, Merlin C Thomas, M. Cooper, 2004, Diabetes.

Role of the renin-angiotensin system in the endocrine pancreas: implications for the development of diabetes.

Merlin C. Thomas, M. Cooper, C. Tikellis, 2006, The international journal of biochemistry & cell biology.

Relationship Between Plasma 8‐OH‐Deoxyguanosine and Cardiovascular Disease and Survival in Type 2 Diabetes Mellitus: Results From the ADVANCE Trial

Merlin C. Thomas, M. Woodward, Merlin C Thomas, 2018, Journal of the American Heart Association.

Activation of the Renin-Angiotensin System Mediates the Effects of Dietary Salt Intake on Atherogenesis in the Apolipoprotein E Knockout Mouse

Merlin C. Thomas, Merlin C Thomas, M. Cooper, 2012, Hypertension.

Chapter 9 – Angiotensin-Converting Enzymes: Properties and Function

C. Johnston, C. Tikellis, 2005 .

A Breaker of Advanced Glycation End Products Attenuates Diabetes‐Induced Myocardial Structural Changes

Merlin C. Thomas, Merlin C Thomas, M. Cooper, 2003, Circulation research.

ACE2 deficiency shifts energy metabolism towards glucose utilization.

Merlin C. Thomas, Merlin C Thomas, M. Cooper, 2015, Metabolism: clinical and experimental.

Advances in the Renin-Angiotensin-Aldosterone System: Relevance to Diabetic Nephropathy

C. Tikellis, A. Koitka, 2008, TheScientificWorldJournal.

Interactions between renin angiotensin system and advanced glycation in the kidney.

Merlin C. Thomas, Merlin C Thomas, M. Cooper, 2005, Journal of the American Society of Nephrology : JASN.

Novel hexad repeats conserved in a putative transporter with restricted expression in cell types associated with growth, calcium exchange and homeostasis.

M. Cooper, C. Kovacs, C. Tikellis, 2004, Experimental cell research.

ACE2 Deficiency Modifies Renoprotection Afforded by ACE Inhibition in Experimental Diabetes

Merlin C. Thomas, C. Johnston, Merlin C Thomas, 2008, Diabetes.

ACE2; an ACE up the Sleeve?

Merlin C Thomas, C. Tikellis, M. Thomas, 2005 .

Dicarbonyl Stress in the Absence of Hyperglycemia Increases Endothelial Inflammation and Atherogenesis Similar to That Observed in Diabetes

Merlin C. Thomas, Merlin C Thomas, M. Cooper, 2014, Diabetes.

Alagebrium Reduces Glomerular Fibrogenesis and Inflammation Beyond Preventing RAGE Activation in Diabetic Apolipoprotein E Knockout Mice

Merlin C. Thomas, Merlin C Thomas, M. Cooper, 2012, Diabetes.

Rho kinase inhibition protects kidneys from diabetic nephropathy without reducing blood pressure.

R. Komers, T. Oyama, S. Anderson, 2011, Kidney international.

Reduced plaque formation induced by rosiglitazone in an STZ-diabetes mouse model of atherosclerosis is associated with downregulation of adhesion molecules.

A. Murphy, M. Cooper, C. Tikellis, 2008, Atherosclerosis.

Angiotensin-Converting Enzyme 2 (ACE2) Is a Key Modulator of the Renin Angiotensin System in Health and Disease

Merlin C. Thomas, C. Tikellis, M. Thomas, 2012, International journal of peptides.

Hyperglycemia Induces a Dynamic Cooperativity of Histone Methylase and Demethylase Enzymes Associated With Gene-Activating Epigenetic Marks That Coexist on the Lysine Tail

M. Cooper, A. El-Osta, M. Brownlee, 2008, Diabetes.

Cellular Biology Distinguishing Hyperglycemic Changes by Set7 in Vascular Endothelial Cells

Merlin C. Thomas, Merlin C Thomas, M. Cooper, 2012 .

Resveratrol Inhibits Growth of Experimental Abdominal Aortic Aneurysm Associated With Upregulation of Angiotensin-Converting Enzyme 2

Merlin C. Thomas, Merlin C Thomas, J. Golledge, 2017, Arteriosclerosis, thrombosis, and vascular biology.

Amylin in the Periphery

M. Cooper, C. Tikellis, L. Xuereb, 2003, TheScientificWorldJournal.

Regulation of angiotensin II receptors in the prostate of the transgenic (mRen-2)27 rat: effect of angiotensin-converting enzyme inhibition.

C. Johnston, C. Tikellis, J. Wilkinson-Berka, 2003, The international journal of biochemistry & cell biology.

High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction.

Merlin C. Thomas, Merlin C Thomas, M. Cooper, 2005, Journal of molecular endocrinology.

Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs.

Merlin C. Thomas, Merlin C Thomas, M. Cooper, 2008, American journal of physiology. Endocrinology and metabolism.

Circulating Soluble ACE2 Plays an Independent Role to Protect against Vascular Damage in Diabetic Mice

C. Tikellis, Carlos J. Rosado, R. Pickering, 2022, Antioxidants.

Angiotensin converting enzyme 2 and atherosclerosis.

Merlin C. Thomas, Merlin C Thomas, J. Golledge, 2013, Atherosclerosis.

The Role of Advanced Glycation in Reduced Organic Cation Transport Associated with Experimental Diabetes

Merlin C. Thomas, Merlin C Thomas, M. Cooper, 2004, Journal of Pharmacology and Experimental Therapeutics.

Amylin binding in rat renal cortex, stimulation of adenylyl cyclase, and activation of plasma renin.

P. Sexton, M. Cooper, C. Tikellis, 1996, The American journal of physiology.

Amylin as a growth factor during fetal and postnatal development of the rat kidney.

M. Cooper, C. Tikellis, D. Casley, 1998, Kidney international.

Short-Term Treatment with Diminazene Aceturate Ameliorates the Reduction in Kidney ACE2 Activity in Rats with Subtotal Nephrectomy

C. Tikellis, L. Burrell, R. Pickering, 2015, PloS one.

ANGIOTENSIN CONVERTING ENZYME 2 IN THE KIDNEY

C. Tikellis, A. Koitka, M. Cooper, 2008, Clinical and experimental pharmacology & physiology.

Developmental expression of ACE2 in the SHR kidney: a role in hypertension?

Merlin C. Thomas, C. Johnston, M. Cooper, 2006, Kidney international.

The intestinal vitamin D receptor in inflammatory bowel disease: inverse correlation with inflammation but no relationship with circulating vitamin D status

Merlin C. Thomas, Merlin C Thomas, P. Gibson, 2019, Therapeutic advances in gastroenterology.

Expression and function of ATIP/MTUS1 in human prostate cancer cell lines

K. Catt, C. Tikellis, W. Louis, 2010, The Prostate.

Ontogeny of calcitonin receptor mRNA and protein in the developing central nervous system of the rat

S. Rees, M. Cooper, C. Tikellis, 2003, The Journal of comparative neurology.

Increased atherosclerosis following treatment with a dual PPAR agonist in the ApoE knockout mouse.

Merlin C Thomas, C. Tikellis, A. Calkin, 2007, Atherosclerosis.

Interaction of diabetes and ACE2 in the pathogenesis of cardiovascular disease in experimental diabetes.

Merlin C. Thomas, Merlin C Thomas, M. Cooper, 2012, Clinical science.

PPARs and diabetes-associated atherosclerosis.

M. Cooper, C. Tikellis, A. Calkin, 2007, Current pharmaceutical design.

Angiotensin-converting enzyme 2 regulates renal atrial natriuretic peptide through angiotensin-(1-7).

Merlin C. Thomas, C. Johnston, Merlin C Thomas, 2012, Clinical science.

High-salt diet increases glomerular ACE/ACE2 ratio leading to oxidative stress and kidney damage.

Merlin C. Thomas, C. Johnston, Merlin C Thomas, 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Angiotensin-converting enzyme 2 mediates hyperfiltration associated with diabetes.

Merlin C Thomas, M. Cooper, C. Tikellis, 2014, American journal of physiology. Renal physiology.

Losing Control: Positive and Negative Feedback in the Renin Angiotensin System

Merlin C Thomas, C. Tikellis, M. Thomas, 2009 .

Reduced tubular cation transport in diabetes: prevented by ACE inhibition.

Merlin C. Thomas, Merlin C Thomas, G. Jerums, 2003, Kidney international.

Amylin and calcitonin gene-related peptide in the rat kidney: functional and autoradiographic studies.

P. Sexton, M. Cooper, C. Tikellis, 1994 .

NEPHRIN EXPRESSION IN THE POST-NATAL DEVELOPING KIDNEY IN NORMOTENSIVE AND HYPERTENSIVE RATS

M. Cooper, H. Kawachi, F. Bonnet, 2002, Clinical and experimental hypertension.

Lipoxins Protect Against Inflammation in Diabetes-Associated Atherosclerosis

M. Cooper, E. Brennan, C. Tikellis, 2018, Diabetes.

Protective Effect of let-7 miRNA Family in Regulating Inflammation in Diabetes-Associated Atherosclerosis

M. Cooper, E. Brennan, C. Tikellis, 2017, Diabetes.

Distinguishing Hyperglycemic Changes by Set7 in Vascular Endothelial Cells

Merlin C. Thomas, M. Cooper, A. El-Osta, 2012, Circulation research.

Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis

Merlin C. Thomas, A. Murphy, E. Fisher, 2020, Circulation research.

Expression analysis of the epigenetic methyltransferases and Methyl-CpG binding protein families in the normal B-cell and B-cell chronic lymphocytic leukemia (CLL)

A. El-Osta, C. Tikellis, K. Harikrishnan, 2004, Cancer biology & therapy.

Osteoprotegerin increases in metabolic syndrome and promotes adipose tissue proinflammatory changes

Merlin C. Thomas, P. Secchiero, G. Zauli, 2014, Molecular and Cellular Endocrinology.

Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2

P. Angus, M. Cooper, C. Tikellis, 2005, Gut.

Characterization of Renal Angiotensin-Converting Enzyme 2 in Diabetic Nephropathy

C. Johnston, M. Cooper, W. Burns, 2003, Hypertension.

Up-regulation of components of the renin-angiotensin system in the bile duct-ligated rat liver.

P. Angus, M. Cooper, C. Tikellis, 2002, Gastroenterology.

Effect of angiotensin II type 1 receptor blockade on experimental hepatic fibrogenesis.

P. Angus, M. Cooper, R. Gilbert, 2001, Journal of hepatology.

Merlin C. Thomas, M. Cooper, P. Secchiero, 2012, Clinical science.

Role of Inflammation and the Angiotensin Type 2 Receptor in the Regulation of Arterial Pressure During Pregnancy in Mice

C. Tikellis, Antony Vinh, K. Denton, 2014, Hypertension.

The Renoprotective Actions of Peroxisome Proliferator-Activated Receptors Agonists in Diabetes

C. Tikellis, K. Jandeleit-Dahm, M. Thomas, 2012, PPAR research.

Imbalance of the renin–angiotensin system may contribute to inflammation and fibrosis in IBD: a novel therapeutic target?

Peter R Gibson, Chin Wee Tan, Merlin C. Thomas, 2019, Gut.

Lipoxins Regulate the Early Growth Response-1 Network and Reverse Diabetic Kidney Disease.

M. Cooper, E. Brennan, A. El-Osta, 2018, Journal of the American Society of Nephrology : JASN.

Why blockade of the renin-angiotensin system reduces the incidence of new-onset diabetes.

C. Reid, C. Johnston, M. Cooper, 2005, Journal of hypertension.

ACE2, a new regulator of the renin–angiotensin system

C. Johnston, M. Cooper, C. Tikellis, 2004, Trends in Endocrinology & Metabolism.

Association of dietary sodium intake with atherogenesis in experimental diabetes and with cardiovascular disease in patients with Type 1 diabetes.

Merlin C. Thomas, D. Gordin, C. Forsblom, 2013, Clinical science.

Direct antiatherosclerotic effects of PPAR agonists

Merlin C. Thomas, C. Tikellis, A. Calkin, 2009, Current opinion in lipidology.

Pyridoxamine prevents increased atherosclerosis by intermittent methylglyoxal spikes in the aortic arches of ApoE-/- mice.

Merlin C. Thomas, A. Murphy, M. Cooper, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Functional angiotensin II type 2 receptors inhibit growth factor signaling in LNCaP and PC3 prostate cancer cell lines

K. Catt, C. Tikellis, W. Louis, 2008, The Prostate.

Portal pressure responses and angiotensin peptide production in rat liver are determined by relative activity of ACE and ACE2.

P. Angus, C. Tikellis, D. Casley, 2009, American journal of physiology. Gastrointestinal and liver physiology.

Quantitative gene expression analysis in kidney tissues.

W. Burns, C. Tikellis, P. Kantharidis, 2009, Methods in molecular biology.

Connective tissue growth factor is up-regulated in the diabetic retina: amelioration by angiotensin-converting enzyme inhibition.

M. Cooper, W. Burns, S. Twigg, 2004, Endocrinology.

Identification of angiotensin converting enzyme 2 in the rodent retina

Merlin C. Thomas, C. Johnston, M. Cooper, 2004, Current eye research.

Heparanase inhibition reduces proteinuria in a model of accelerated anti‐glomerular basement membrane antibody disease

M. Cooper, C. Tikellis, V. Levidiotis, 2005, Nephrology.

Heparanase is involved in the pathogenesis of proteinuria as a result of glomerulonephritis.

D. Power, M. Cooper, C. Tikellis, 2004, Journal of the American Society of Nephrology : JASN.

Polymorphisms in the gene encoding angiotensin I converting enzyme 2 and diabetic nephropathy

S. Fröjdö, C. Forsblom, M. Cooper, 2005, Diabetologia.

Preventing diabetes in patients with hypertension: one more reason to block the renin–angiotensin system

Merlin C. Thomas, M. Cooper, C. Tikellis, 2006, Journal of Hypertension - Supplement.

Protective Effect of Inflammasome Activation by Hydrogen Peroxide in a Mouse Model of Septic Shock

M. Cooper, B. Kingwell, J. D. de Haan, 2017, Critical care medicine.

Interactions between renin angiotensin system and advanced glycation in the kidney.

Merlin C. Thomas, J. Forbes, C. Tikellis, 2005, Journal of the American Society of Nephrology : JASN.

Rho kinase inhibition protects kidneys from diabetic nephropathy without reducing blood pressure.

R. Komers, T. Oyama, S. Anderson, 2011, Kidney international.

Portal pressure responses and angiotensin peptide production in rat liver are determined by relative activity of ACE and ACE2.

P. Angus, C. Tikellis, D. Casley, 2009, American journal of physiology. Gastrointestinal and liver physiology.

Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2

P. Angus, C. Tikellis, L. Burrell, 2005, Gut.

Erratum: ACE2 deficiency modifies renoprotection afforded by ACE inhibition in experimental diabetes (Diabetes (2008) 57 (1018-1025))

Merlin C. Thomas, C. Johnston, J. Pete, 2011 .