Valerie Le Sage

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Cell-Culture Adaptation of H3N2 Influenza Virus Impacts Acid Stability and Reduces Airborne Transmission in Ferret Model

J. Bloom, Juhye M. Lee, S. Lakdawala, 2021, Viruses.

Cell Culture Adaptation of H3N2 Influenza Virus Impacts Acid Stability and Reduces Ferret Airborne Transmission

J. Bloom, Juhye M. Lee, S. Lakdawala, 2021 .

An outer membrane protease of the omptin family prevents activation of the Citrobacter rodentium PhoPQ two‐component system by antimicrobial peptides

Lei Zhu, A. Portt, F. Daigle, 2009, Molecular microbiology.

Secondary infection with Streptococcus pneumoniae decreases influenza virus replication and is linked to severe disease

S. Lakdawala, S. Schultz-Cherry, N. Hiller, 2022, FEMS microbes.

Quantitative live cell imaging reveals influenza virus manipulation of Rab11A transport through reduced dynein association

M. Weitzman, B. Garcia, H. Shroff, 2020, Nature Communications.

A Cross-Sectional Study of SARS-CoV-2 Seroprevalence between Fall 2020 and February 2021 in Allegheny County, Western Pennsylvania, USA

A. McElroy, W. P. Duprex, Valerie Le Sage, 2021, Pathogens.

Pre-existing heterosubtypic immunity provides a barrier to airborne transmission of influenza viruses

R. Manivanh, S. Lakdawala, S. Hensley, 2021, PLoS pathogens.

HIV-1 Gag Blocks Selenite-Induced Stress Granule Assembly by Altering the mRNA Cap-Binding Complex

Valerie Le Sage, A. Mouland, A. Cinti, 2016, mBio.

Dysregulation of Autophagy in Murine Fibroblasts Resistant to HSV-1 Infection

B. Banfield, Valerie Le Sage, 2012, PloS one.

Pre-existing immunity provides a barrier to airborne transmission of influenza viruses

R. Manivanh, S. Lakdawala, S. Hensley, 2020, bioRxiv.

Absence of PmrAB-Mediated Phosphoethanolamine Modifications of Citrobacter rodentium Lipopolysaccharide Affects Outer Membrane Integrity

H. Le Moual, Valerie Le Sage, Charles Viau, 2011, Journal of bacteriology.

Live Imaging of Influenza Viral Ribonucleoproteins Using Light-Sheet Microscopy.

S. Lakdawala, Valerie Le Sage, Amar R. Bhagwat, 2018, Methods in molecular biology.

The Us2 Gene Product of Herpes Simplex Virus 2 Is a Membrane-Associated Ubiquitin-Interacting Protein

B. Banfield, Hui Zhang, Ming Kang, 2013, Journal of Virology.

Viral and host heterogeneity and their effects on the viral life cycle

S. Lakdawala, Valerie Le Sage, Jennifer E. Jones, 2020, Nature Reviews Microbiology.

Differentiating the Roles of UL16, UL21, and Us3 in the Nuclear Egress of Herpes Simplex Virus Capsids

B. Banfield, Jie Gao, Valerie Le Sage, 2020, Journal of Virology.

Differentiating the Roles of UL16, UL21 and Us3 in the Nuclear Egress of Herpes Simplex Virus Capsids

B. Banfield, Jie Gao, Valerie Le Sage, 2020, bioRxiv.

Proteomic analysis of HIV-1 Gag interacting partners using proximity-dependent biotinylation

Valerie Le Sage, A. Mouland, A. Cinti, 2015, Virology Journal.

Adapting the Stress Response: Viral Subversion of the mTOR Signaling Pathway

Valerie Le Sage, A. Mouland, A. Cinti, 2016, Viruses.

Ebola virus VP35 blocks stress granule assembly.

Valerie Le Sage, A. Mouland, E. Tramontano, 2017, Virology.

The Herpes Simplex Virus 2 UL21 Protein Is Essential for Virus Propagation

B. Banfield, Y. Kawaguchi, J. Baines, 2013, Journal of Virology.

Functional Evidence for the Involvement of Microtubules and Dynein Motor Complexes in TRIM5α-Mediated Restriction of Retroviruses

M. Tremblay, L. Berthoux, Valerie Le Sage, 2014, Journal of Virology.

HIV-1 enhances mTORC1 activity and repositions lysosomes to the periphery by co-opting Rag GTPases

M. Olivier, Valerie Le Sage, Miroslav P. Milev, 2017, Scientific Reports.

Viral Subversion of the Nuclear Pore Complex

Valerie Le Sage, A. Mouland, 2013, Viruses.

Mapping of Influenza Virus RNA-RNA Interactions Reveals a Flexible Network.

V. Cooper, S. Lakdawala, Valerie Le Sage, 2020, Cell reports.

Altered Nucleoprotein Binding to Influenza Virus RNA Impacts Packaging Efficiency and Replication

V. Cooper, S. Lakdawala, Valerie Le Sage, 2019, bioRxiv.

Non-Uniform and Non-Random Binding of Nucleoprotein to Influenza A and B Viral RNA

V. Cooper, S. Lakdawala, Valerie Le Sage, 2018, Viruses.

Genome-wide analysis of influenza viral RNA and nucleoprotein association

V. Cooper, S. Lakdawala, Valerie Le Sage, 2017, Nucleic acids research.

Roles of HIV-1 capsid in viral replication and immune evasion.

Valerie Le Sage, A. Mouland, F. Valiente-Echeverría, 2014, Virus research.

A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes

D. Weissman, S. Lakdawala, S. Hensley, 2022, Science.

Activation of the bacterial sensor kinase PhoQ by acidic pH.

Samuel I. Miller, R. Klevit, H. Le Moual, 2007, Molecular cell.

Original antigenic sin priming of influenza virus hemagglutinin stalk antibodies

A. Gordon, Á. Balmaseda, S. Lakdawala, 2020, Proceedings of the National Academy of Sciences.

No-Go'ing Back: Co-opting RVB-2 to Control HIV-1 Gene Expression and Immune Response.

Valerie Le Sage, A. Mouland, A. Cinti, 2015, Trends in Microbiology.

Variability in Donor Lung Culture and Relative Humidity Impact the Stability of 2009 Pandemic H1N1 Influenza Virus on Nonporous Surfaces

Dylan H. Morris, J. Lloyd-Smith, S. Lakdawala, 2023, bioRxiv.

Local changes in viral RNA sequence drive global changes in influenza nucleoprotein binding

S. Lakdawala, Valerie Le Sage, Nara Lee, 2023, Journal of Medical Virology.

Seasonal influenza viruses decay more rapidly at intermediate humidity in droplets containing saliva compared to respiratory mucus

S. Lakdawala, L. Marr, Valerie Le Sage, 2023, bioRxiv.

Roles of HIV-1 capsid in viral replication and immune evasion.

Valerie Le Sage, A. Mouland, F. Valiente-Echeverría, 2014, Virus research.

Detection of influenza virus and Streptococcus pneumoniae in air sampled from co-infected ferrets and analysis of their influence on pathogen stability

S. Lakdawala, M. Myerburg, N. Hiller, 2023, bioRxiv.