Sophia T. Mundle

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Mapping of a Novel H3-Specific Broadly Neutralizing Monoclonal Antibody Targeting the Hemagglutinin Globular Head Isolated from an Elite Influenza Virus-Immunized Donor Exhibiting Serological Breadth.

T. Vogel, P. Prabakaran, Huawei Qiu, 2019 .

Mapping of a Novel H3-Specific Broadly Neutralizing Monoclonal Antibody Targeting the Hemagglutinin Globular Head Isolated from an Elite Influenza Virus-Immunized Donor Exhibiting Serological Breadth

T. Vogel, P. Prabakaran, Huawei Qiu, 2019, Journal of Virology.

Novel structural insights for a pair of monoclonal antibodies recognizing non-overlapping epitopes of the glucosyltransferase domain of Clostridium difficile toxin B

Svetlana S. Stegalkina, Jianxin Zhang, Sophia T. Mundle, 2022, Current research in structural biology.

Immunogenicity and protective efficacy of RSV G central conserved domain vaccine with a prefusion nanoparticle

G. Nabel, S. Delagrave, Sophia T. Mundle, 2022, npj Vaccines.

Immunogenicity and Efficacy of Intramuscular Replication-Defective and Subunit Vaccines against Herpes Simplex Virus Type 2 in the Mouse Genital Model

M. Parrington, S. Delagrave, Sophia T. Mundle, 2012, PloS one.

A Combination of Three Fully Human Toxin A- and Toxin B-Specific Monoclonal Antibodies Protects against Challenge with Highly Virulent Epidemic Strains of Clostridium difficile in the Hamster Model

Jianxin Zhang, Sophia T. Mundle, H. Kleanthous, 2015, Clinical and Vaccine Immunology.

Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus

E. Chautard, J. McLellan, C. Hsieh, 2022, bioRxiv.

Core bead chromatography for preparation of highly pure, infectious respiratory syncytial virus in the negative purification mode.

M. Parrington, Sophia T. Mundle, H. Kleanthous, 2016, Vaccine.

Enzymatic mechanism of human apurinic/apyrimidinic endonuclease against a THF AP site model substrate

Sophia T. Mundle, J. Delaney, P. Strauss, 2009, Biochemistry.

Influenza vaccination in the elderly boosts antibodies against conserved viral proteins and egg-produced glycans.

Jonathan R. McDaniel, D. Boutz, G. Georgiou, 2021, Journal of Clinical Investigation.

High-Purity Preparation of HSV-2 Vaccine Candidate ACAM529 Is Immunogenic and Efficacious In Vivo

S. Delagrave, Svetlana S. Stegalkina, Sophia T. Mundle, 2013, PloS one.

Pre-existing Fc profiles shape the evolution of neutralizing antibody breadth following influenza vaccination

D. Lingwood, S. Delagrave, T. Ross, 2023, Cell reports. Medicine.

Novel role of tyrosine in catalysis by human AP endonuclease 1.

Sophia T. Mundle, P. Strauss, N. E. O'Regan, 2004, DNA repair.

Development of multivalent mRNA vaccine candidates for seasonal or pandemic influenza

F. Derosa, Sophia T. Mundle, D. Casimiro, 2021, NPJ vaccines.

Impact of age and pre-existing influenza immune responses in humans receiving split inactivated influenza vaccine on the induction of the breadth of antibodies to influenza A strains

James D. Allen, T. Vogel, S. Delagrave, 2017, PloS one.

Preparation of pure, high titer, pseudoinfectious Flavivirus particles by hollow fiber tangential flow filtration and anion exchange chromatography.

M. Giel-Moloney, Sophia T. Mundle, H. Kleanthous, 2015, Vaccine.

Role of active site tyrosines in dynamic aspects of DNA binding by AP endonuclease.

Sophia T. Mundle, P. Strauss, N. E. O'Regan, 2007, DNA repair.

Immunogenicity and protective efficacy of RSV G central conserved domain vaccine with a prefusion nanoparticle

G. Nabel, S. Delagrave, Sophia T. Mundle, 2022, npj Vaccines.

Development of multivalent mRNA vaccine candidates for seasonal or pandemic influenza

F. Derosa, Sophia T. Mundle, D. Casimiro, 2021, npj Vaccines.

Deciphering the domain specificity of C. difficile toxin neutralizing antibodies.

Jianxin Zhang, Sophia T. Mundle, H. Kleanthous, 2019, Vaccine.

Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.

J. McLellan, C. Hsieh, Sophia T. Mundle, 2022, Cell reports.

A Combination of Three Fully Human Toxin A- and Toxin B-Specific Monoclonal Antibodies Protects against Challenge with Highly Virulent Epidemic Strains of Clostridium difficile in the Hamster Model

Jianxin Zhang, Sophia T. Mundle, H. Kleanthous, 2015, Clinical and Vaccine Immunology.

Crystal structure of C585 Fab in complex with influenza virus hemagglutinin from A/Switzerland/9715293/2013 (H3N2)

P. Prabakaran, Ekaterina Boudanova, Yanfeng Zhou, 2019 .