M. Mahan

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An intrinsic mechanism of secreted protein aging and turnover

Jeffrey W. Smith, J. Marth, W. Yang, 2015, Proceedings of the National Academy of Sciences of the United States of America.

The Salmonella typbimurium RecJ function permits growth of P22 abc phage on recBCD+ hosts

J. Roth, J. Casadesús, M. Mahan, 1992, Molecular and General Genetics MGG.

Microfluidic Chip-Based Detection and Intraspecies Strain Discrimination of Salmonella Serovars Derived from Whole Blood of Septic Mice

Kevin W. Plaxco, H. Tom Soh, H. Soh, 2013, Applied and Environmental Microbiology.

Revealing bacterial infection strategies

M. Mahan, 1994, The Lancet.

Reciprocality of recombination events that rearrange the chromosome.

J. Roth, M. Mahan, John R. Roth, 1988, Genetics.

Immunization with a DNA adenine methylase over-producing Yersinia pseudotuberculosis vaccine confers robust cross-protection against heterologous pathogenic serotypes.

D. M. Heithoff, M. Mahan, J. Kubicek-Sutherland, 2014, Vaccine.

Smartphone-based pathogen diagnosis in urinary sepsis patients

J. Marth, H. Soh, D. M. Heithoff, 2018, EBioMedicine.

DNA Adenine Methylase Overproduction in Yersinia pseudotuberculosis Alters YopE Expression and Secretion and Host Immune Responses to Infection

D. Low, D. M. Heithoff, M. Mahan, 2002, Infection and Immunity.

Salmonella DNA Adenine Methylase Mutants Elicit Protective Immune Responses to Homologous and Heterologous Serovars in Chickens

D. M. Heithoff, M. Mahan, E. Dueger, 2001, Infection and Immunity.

Single-step conjugative cloning of bacterial gene fusions involved in microbe-host interactions

P. Rainey, D. M. Heithoff, M. Mahan, 1997, Molecular and General Genetics MGG.

GUEST COMMENTARY Vibrio cholerae Bioﬁlms: Stuck between a Rock and a Hard Place

D. M. Heithoff, M. Mahan, 2004 .

Smartphone-based diagnosis in urinary sepsis patients.

J. Marth, D. M. Heithoff, M. Mahan, 2018 .

Neu3 neuraminidase induction triggers intestinal inflammation and colitis in a model of recurrent human food-poisoning

J. Marth, M. Sperandio, W. Yang, 2021, Proceedings of the National Academy of Sciences.

Conditions That Diminish Myeloid-Derived Suppressor Cell Activities Stimulate Cross-Protective Immunity

R. Daynes, D. M. Heithoff, M. Mahan, 2008, Infection and Immunity.

Development of a Salmonella cross-protective vaccine for food animal production systems.

D. M. Heithoff, M. Mahan, P. Thomson, 2015, Vaccine.

Directed formation of chromosomal deletions in Salmonella typhimurium : targeting of specific genes induced during infection

D. M. Heithoff, M. Mahan, S. M. Julio, 1998, Molecular and General Genetics MGG.

Pathogenesis Serovar Typhimurium enterica Salmonella ( tmRNA ) Plays a Role in ssrA

D. M. Heithoff, M. Mahan, S. M. Julio, 2000 .

In vivo gene expression: contributions to infection, virulence, and pathogenesis.

D. M. Heithoff, M. Mahan, C. Conner, 1998, Current topics in microbiology and immunology.

Human Salmonella Clinical Isolates Distinct from Those of Animal Origin

R. Daynes, D. M. Heithoff, M. Mahan, 2008, Applied and Environmental Microbiology.

In Vivo-Induced Genes in Pseudomonas aeruginosa

M. Handfield, F. Sanschagrin, M. Mahan, 2000, Infection and Immunity.

Salmonella cross-protective vaccines: fast-forward to the next generation of food safety.

D. M. Heithoff, M. Mahan, J. House, 2012, Future microbiology.

Correcting a Fundamental Flaw in the Paradigm for Antimicrobial Susceptibility Testing

Jeffrey W. Smith, J. Marth, D. M. Heithoff, 2017, EBioMedicine.

Dissecting the biology of a pathogen during infection.

D. M. Heithoff, M. Mahan, C. Conner, 1997, Trends in microbiology.

Cross-protective immunity conferred by a DNA adenine methylase deficient Salmonella enterica serovar Typhimurium vaccine in calves challenged with Salmonella serovar Newport.

D. M. Heithoff, M. Mahan, M. Hornitzky, 2008, Vaccine.

LcrV Synthesis Is Altered by DNA Adenine Methylase Overproduction in Yersinia pseudotuberculosis and Is Required To Confer Immunity in Vaccinated Hosts

D. M. Heithoff, M. Mahan, Golnaz Badie, 2004, Infection and Immunity.

Confer Immunity in Vaccinated Hosts and Is Required To pseudotuberculosis Yersinia Methylase Overproduction in LcrV Synthesis Is Altered by DNA Adenine

D. M. Heithoff, M. Mahan, Golnaz Badie, 2004 .

Role of recBC function in formation of chromosomal rearrangements: a two-step model for recombination.

J. Roth, M. Mahan, 1989, Genetics.

Protective immunity conferred by a DNA adenine methylase deficient Salmonella enterica serovar Typhimurium vaccine when delivered in-water to sheep challenged with Salmonella enterica serovar Typhimurium.

A. Thompson, D. M. Heithoff, M. Mahan, 2011, Vaccine.

Establishment of blood glycosidase activities and their excursions in sepsis

J. Marth, Peter V Aziz, D. M. Heithoff, 2022, PNAS nexus.

Genetic analysis of the proBA genes of Salmonella typhimurium: physical and genetic analyses of the cloned proB+ A+ genes of Escherichia coli and of a mutant allele that confers proline overproduction and enhanced osmotolerance

M. Mahan, L. Csonka, 1983, Journal of bacteriology.

Differential patterns of acquired virulence genes distinguish Salmonella strains.

D. M. Heithoff, M. Mahan, R. Sinsheimer, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Host-dependent Induction of Transient Antibiotic Resistance: A Prelude to Treatment Failure

Jeffrey W. Smith, J. Marth, D. M. Heithoff, 2015, EBioMedicine.

Bacterial Infection: Close Encounters at the Host Pathogen Interface

P. Vogt, M. Mahan, 1998, Current Topics in Microbiology and Immunology.

Recurrent infection progressively disables host protection against intestinal inflammation

V. Nizet, J. Marth, M. Sperandio, 2017, Science.

Epigenetic Programming by Microbial Pathogens and Impacts on Acute and Chronic Disease

D. M. Heithoff, M. Mahan, R. Sinsheimer, 2017 .

Accelerated Aging and Clearance of Host Anti-inflammatory Enzymes by Discrete Pathogens Fuels Sepsis.

V. Nizet, J. Marth, J. Millán, 2018, Cell host & microbe.

Covert Operations: the Adaptable Plan of Attack Deployed by Pathogenic Bacteria

D. M. Heithoff, M. Mahan, R. Sinsheimer, 2011 .

Plasma Proteome Signature of Sepsis: a Functionally Connected Protein Network

Jeffrey W. Smith, J. Marth, J. Esko, 2019, Proteomics.

Rise of the microbes

D. M. Heithoff, M. Mahan, J. Kubicek-Sutherland, 2013, Virulence.

Assessment of a Smartphone-Based Loop-Mediated Isothermal Amplification Assay for Detection of SARS-CoV-2 and Influenza Viruses

D. Low, D. M. Heithoff, M. Mahan, 2022, JAMA network open.

Development of a novel in-water vaccination protocol for DNA adenine methylase deficient Salmonella enterica serovar Typhimurium vaccine in adult sheep.

D. M. Heithoff, M. Mahan, P. Thomson, 2012, Vaccine.

Ability of a bacterial chromosome segment to invert is dictated by included material rather than flanking sequence.

J R Roth, J. Roth, M. Mahan, 1991, Genetics.

Rearrangement of the bacterial chromosome: forbidden inversions.

A. Segall, J. Roth, M. Mahan, 1988, Science.

Vibrio cholerae Biofilms: Stuck between a Rock and a Hard Place

D. M. Heithoff, M. Mahan, 2004, Journal of bacteriology.

An essential role for DNA adenine methylation in bacterial virulence.

D. Low, D. M. Heithoff, M. Mahan, 1999, Science.

Techniques, Hosting an infection: the complex interplay between microbes and their hosts: Editorial overview

D. Low, M. Mahan, 2001 .

Salmonella DNA adenine methylase mutants prevent colonization of newly hatched chickens by homologous and heterologous serovars.

D. M. Heithoff, M. Mahan, E. Dueger, 2003, International journal of food microbiology.

Comparison of Tissue-Selective Proinflammatory Gene Induction in Mice Infected with Wild-Type, DNA Adenine Methylase-Deficient, and Flagellin-Deficient Salmonella enterica

C. Samuel, D. M. Heithoff, M. Mahan, 2007, Infection and Immunity.

Salmonella DNA Adenine Methylase Mutants Confer Cross-Protective Immunity

D. Low, R. Daynes, D. M. Heithoff, 2001, Infection and Immunity.

Altered Levels of Salmonella DNA Adenine Methylase Are Associated with Defects in Gene Expression, Motility, Flagellar Synthesis, and Bile Resistance in the Pathogenic Strain 14028 but Not in the Laboratory Strain LT2

D. M. Heithoff, M. Mahan, R. Sinsheimer, 2006, Journal of bacteriology.

Tissue Selectivity of Interferon-Stimulated Gene Expression in Mice Infected with Dam+ versus Dam−Salmonella enterica Serovar Typhimurium Strains

C. Samuel, R. Shtrichman, D. M. Heithoff, 2002, Infection and Immunity.

Roles of DNA Adenine Methylation in Regulating Bacterial Gene Expression and Virulence

D. Low, M. Mahan, N. Weyand, 2001, Infection and Immunity.

Intraspecies Variation in the Emergence of Hyperinfectious Bacterial Strains in Nature

Bart C. Weimer, John K. House, Robert L. Sinsheimer, 2012, PLoS pathogens.

DNA Adenine Methylase Is Essential for Viability and Plays a Role in the Pathogenesis of Yersinia pseudotuberculosis andVibrio cholerae

D. Low, K. Klose, D. Provenzano, 2001, Infection and Immunity.

, Vibrio cholerae and pseudotuberculosis Yersinia Pathogenesis of Viability and Plays a Role in the DNA Adenine Methylase Is Essential for

D. Low, K. Klose, D. Provenzano, 2001 .

recB recJ mutants ofSalmonella typhimurium are deficient in transductional recombination, DNA repair and plasmid maintenance

A. Garzón, J. Casadesús, M. Mahan, 1996, Molecular and General Genetics MGG.

ssrA (tmRNA) Plays a Role inSalmonella enterica Serovar Typhimurium Pathogenesis

D. M. Heithoff, M. Mahan, S. M. Julio, 2000, Journal of bacteriology.

Assessment of bacterial pathogenesis by analysis of gene expression in the host.

D. Low, D. M. Heithoff, M. Mahan, 2000, Annual review of genetics.

Coordinate Intracellular Expression ofSalmonella Genes Induced during Infection

F. Govantes, U. Hentschel, D. M. Heithoff, 1999, Journal of bacteriology.

Bacterial infection as assessed by in vivo gene expression.

U. Hentschel, D. M. Heithoff, M. Mahan, 1997, Proceedings of the National Academy of Sciences of the United States of America.

In vivo gene expression and the adaptive response: from pathogenesis to vaccines and antimicrobials.

D. Low, D. M. Heithoff, M. Mahan, 2000, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

recB and recC genes of Salmonella typhimurium

J. Roth, M. Mahan, 1989, Journal of bacteriology.

Coagulation factor protein abundance in the pre-septic state predicts coagulopathic activities that arise during late-stage murine sepsis

Jeffrey W. Smith, J. Marth, W. Yang, 2022, EBioMedicine.

Re-evaluation of FDA-approved antibiotics with increased diagnostic accuracy for assessment of antimicrobial resistance

D. M. Heithoff, M. Mahan, Lucien Barnes V, 2023, Cell reports. Medicine.

A broad-spectrum synthetic antibiotic that does not evoke bacterial resistance

A. Osterman, G. Bazan, D. Low, 2023, EBioMedicine.

In Vivo-Selected Mutations in Methyl-Directed Mismatch Repair Suppress the Virulence Attenuation of Salmonella dam Mutant Strains following Intraperitoneal, but Not Oral, Infection of Naïve Mice

R. Daynes, D. M. Heithoff, M. Mahan, 2007, Journal of bacteriology.

Salmonella DNA adenine methylase mutants elicit early and late onset protective immune responses in calves.

D. M. Heithoff, M. Mahan, E. Dueger, 2003, Vaccine.

Host RecJ is required for growth of P22 erf bacteriophage

A. Garzón, J. Casadesús, M. Mahan, 1993, Journal of bacteriology.

Cross-protective immunity in calves conferred by a DNA adenine methylase deficient Salmonellaenterica serovar Typhimurium vaccine.

D. M. Heithoff, M. Mahan, M. Hornitzky, 2006, Vaccine.

Pandemic influenza virus: tracking a three-headed monster

D. M. Heithoff, M. Mahan, 2015, Virulence.

Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimurium

J. Mekalanos, M. Mahan, M. Mahan, 1992, Infection and immunity.

Innate mechanism of mucosal barrier erosion in the pathogenesis of acquired colitis

J. Marth, W. Yang, D. M. Heithoff, 2023, iScience.

Molecular characterization of the oafA locus responsible for acetylation of Salmonella typhimurium O-antigen: oafA is a member of a family of integral membrane trans-acylases

J. Mekalanos, M. Mahan, M. Mahan, 1996, Journal of bacteriology.

Antimicrobial susceptibility testing to evaluate minimum inhibitory concentration values of clinically relevant antibiotics

D. M. Heithoff, M. Mahan, Lucien Barnes V, 2023, STAR protocols.