W. Van Breedam

发表

Bitter-sweet symphony: glycan–lectin interactions in virus biology

H. Favoreel, H. Nauwynck, R. D. de Groot, 2014, FEMS microbiology reviews.

The M/GP5 Glycoprotein Complex of Porcine Reproductive and Respiratory Syndrome Virus Binds the Sialoadhesin Receptor in a Sialic Acid-Dependent Manner

H. Nauwynck, W. Van Breedam, P. Crocker, 2010, PLoS pathogens.

GlycoVHH: Introducing N-glycans on the camelid VHH antibody scaffold

N. Callewaert, Iebe Rossey, B. Schepens, 2022, bioRxiv.

Sialoadhesin and CD163 join forces during entry of the porcine reproductive and respiratory syndrome virus.

H. Nauwynck, W. Van Breedam, H. Van Gorp, 2008, The Journal of general virology.

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies

N. Callewaert, B. Graham, J. McLellan, 2020, Cell.

Comparison of the efficacy of autogenous inactivated Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) vaccines with that of commercial vaccines against homologous and heterologous challenges

H. Nauwynck, W. Van Breedam, J. Van Doorsselaere, 2012, BMC Veterinary Research.

Porcine reproductive and respiratory syndrome virus (PRRSV)-specific mAbs: supporting diagnostics and providing new insights into the antigenic properties of the virus.

H. Nauwynck, C. Gagnon, W. Van Breedam, 2011, Veterinary immunology and immunopathology.

IFN-alpha treatment enhances porcine Arterivirus infection of monocytes via upregulation of the porcine Arterivirus receptor sialoadhesin.

H. Nauwynck, W. Van Breedam, K. Reeth, 2007, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Demonstration of microchimerism in pregnant sows and effects of congenital PRRSV infection

C. Rogel-Gaillard, H. Nauwynck, N. Van Roy, 2012, Veterinary Research.

GlyConnect: a glycan-based conjugation extension of the GlycoDelete technology

N. Callewaert, W. Van Breedam, W. Nerinckx, 2021, bioRxiv.

Antibody response and maternal immunity upon boosting PRRSV-immune sows with experimental farm-specific and commercial PRRSV vaccines.

H. Nauwynck, D. Maes, W. Van Breedam, 2013, Veterinary microbiology.

Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage.

H. Nauwynck, W. Van Breedam, H. Van Gorp, 2010, The Journal of general virology.

Detection of total and PRRSV-specific antibodies in oral fluids collected with different rope types from PRRSV-vaccinated and experimentally infected pigs

I. Decorte, A. Cay, N. De Regge, 2014, BMC Veterinary Research.

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies

N. Callewaert, B. Graham, J. McLellan, 2020, Cell.

Porcine Arterivirus Attachment to the Macrophage-Specific Receptor Sialoadhesin Is Dependent on the Sialic Acid-Binding Activity of the N-Terminal Immunoglobulin Domain of Sialoadhesin

H. Nauwynck, W. Van Breedam, P. Crocker, 2007, Journal of Virology.

Characterization of antigenic regions in the porcine reproductive and respiratory syndrome virus by the use of peptide-specific serum antibodies.

H. Nauwynck, W. Van Breedam, M. Vanhee, 2011, Vaccine.

Identification of the CD163 Protein Domains Involved in Infection of the Porcine Reproductive and Respiratory Syndrome Virus

H. Nauwynck, W. Van Breedam, J. Van Doorsselaere, 2009, Journal of Virology.

Molecular cloning of porcine Siglec-3, Siglec-5 and Siglec-10, and identification of Siglec-10 as an alternative receptor for porcine reproductive and respiratory syndrome virus (PRRSV)

H. Nauwynck, W. Van Breedam, Jiexiong Xie, 2017, The Journal of general virology.

Porcine, murine and human sialoadhesin (Sn/Siglec-1/CD169): portals for porcine reproductive and respiratory syndrome virus entry into target cells.

H. Nauwynck, W. Van Breedam, M. Verbeeck, 2013, The Journal of general virology.

GP4-specific neutralizing antibodies might be a driving force in PRRSV evolution.

H. Nauwynck, W. Van Breedam, J. Van Doorsselaere, 2010, Virus research.

A variable region in GP4 of European-type porcine reproductive and respiratory syndrome virus induces neutralizing antibodies against homologous but not heterologous virus strains.

H. Nauwynck, W. Van Breedam, J. Van Doorsselaere, 2010, Viral immunology.

Micro-dissecting the pathogenesis and immune response of PRRSV infection paves the way for more efficient PRRSV vaccines.

H. Nauwynck, W. Van Breedam, M. Verbeeck, 2012, Transboundary and emerging diseases.

An affinity-enhanced, broadly neutralizing heavy chain–only antibody protects against SARS-CoV-2 infection in animal models

P. Maes, N. Callewaert, B. Weynand, 2021, Science Translational Medicine.

Drug development of an affinity enhanced, broadly neutralizing heavy chain-only antibody that restricts SARS-CoV-2 in rodents

P. Maes, N. Callewaert, B. Weynand, 2021, bioRxiv.

GlycoVHH: optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery

N. Callewaert, A. Mehdipour, Iebe Rossey, 2023, mAbs.

GlycoVHH: Introducing N-glycans on the camelid VHH antibody scaffold - Optimal sites and use for macrophage delivery

N. Callewaert, A. Mehdipour, Iebe Rossey, 2022, bioRxiv.