Kai Xu

发表

Ephrin-B2 and ephrin-B3 as functional henipavirus receptors.

C. Broder, Kai Xu, D. Nikolov, 2012, Seminars in cell & developmental biology.

MicroRNA-124 suppresses tumor cell proliferation and invasion by targeting CD164 signaling pathway in non-small cell lung cancer.

Kai Xu, Lin Ji, Jack A Roth, 2016, Journal of gene therapy.

Tumor-specific Activation of Human Telomerase Reverses Transcriptase Promoter Activity by Activating Enhancer-binding Protein-2β in Human Lung Cancer Cells*

J. Roth, L. Ji, Kai Xu, 2007, Journal of Biological Chemistry.

Overexpression of the Novel Tumor Suppressor Gene FUS1 Suppresses the Growth of Small Cell Lung Cancer Cells

J. Roth, L. Ji, H. Poulsen, 2011 .

Overexpression of Glypican 5 (GPC5) Inhibits Prostate Cancer Cell Proliferation and Invasion via Suppressing Sp1-Mediated EMT and Activation of Wnt/β-Catenin Signaling

Kai Xu, M. He, Yu Sun, 2018, Oncology research.

Aflatoxin exposure produces serum alphafetoprotein elevations and marked oval cell proliferation in young male Pekin ducklings

S. Sell, Kai Xu, W. Huff, 1998, Pathology.

The Effect of Adenovirus-Mediated Gene Expression of FHIT in Small Cell Lung Cancer Cells

J. Roth, L. Ji, H. Poulsen, 2011, Cancer investigation.

Upregulation of DUSP14 Affects Proliferation, Invasion and Metastasis, Potentially via Epithelial–Mesenchymal Transition and Is Associated with Poor Prognosis in Pancreatic Cancer

Jingcheng Zhang, Kai Xu, Gang Wang, 2020, Cancer management and research.

Somatostatin Receptor Type 2–Based Reporter Expression after Plasmid-Based in Vivo Gene Delivery to Non–Small Cell Lung Cancer

J. Roth, L. Ji, Kai Xu, 2013, Molecular imaging.

Cellular and humoral immune responses to adenovirus and p53 protein antigens in patients following intratumoral injection of an adenovirus vector expressing wild-type p53 (Ad-p53)

F. Khuri, W. Hong, J. Roth, 2000, Cancer Gene Therapy.

Synergistic tumor suppression by coexpression of FUS1 and p53 is associated with down-regulation of murine double minute-2 and activation of the apoptotic protease-activating factor 1-dependent apoptotic pathway in human non-small cell lung cancer cells.

J. Minna, J. Roth, L. Ji, 2007, Cancer research.

Regulation of tumor suppressor gene FUS1 expression by the untranslated regions of mRNA in human lung cancer cells.

J. Roth, L. Ji, Kai Xu, 2011, Biochemical and biophysical research communications.

Establishing a GMP manufacturing site for nanoparticles

Kai Xu, Lin Ji, Charles Lu, 2007 .

Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus

C. Broder, R. Cattaneo, Kai Xu, 2019, Proceedings of the National Academy of Sciences.

Crystal structures of Lgr4 and its complex with R-spondin1.

K. Rajashankar, Kai Xu, D. Nikolov, 2013, Structure.

MicroRNA-31 controls phenotypic modulation of human vascular smooth muscle cells by regulating its target gene cellular repressor of E1A-stimulated genes.

J. Tao, Chenghui Yan, Ya‐Ling Han, 2013, Experimental cell research.

Fragile histidine triad-mediated tumor suppression of lung cancer by targeting multiple components of the Ras/Rho GTPase molecular switch.

J. Minna, J. Roth, L. Girard, 2007, Cancer research.

Detection of siRNA-mediated target mRNA cleavage activities in human cells by a novel stem-loop array RT-PCR analysis

J. Roth, L. Ji, Kai Xu, 2016, Biochemistry and biophysics reports.

CACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrity

Kai Xu, Lin Ji, John D Minna, 2003, Oncogene.

A novel single tetracycline-regulative adenoviral vector for tumor-specific Bax gene expression and cell killing in vitro and in vivo

J. Gu, J. Roth, B. Fang, 2002, Oncogene.

Liposomal vector mediated delivery of the 3p FUS1 gene demonstrates potent antitumor activity against human lung cancer in vivo

J. Minna, J. Roth, R. Ramesh, 2004, Cancer Gene Therapy.

Expression of several genes in the human chromosome 3p21.3 homozygous deletion region by an adenovirus vector results in tumor suppressor activities in vitro and in vivo.

J. Minna, J. Roth, M. Lerman, 2002, Cancer research.

Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism

N. Renier, Zhuhao Wu, M. Tessier-Lavigne, 2014, Science.

Homotypic receptor-receptor interactions regulating Eph signaling

Kai Xu, D. Nikolov, J. Himanen, 2014, Cell adhesion & migration.

Immunization strategies against henipaviruses.

C. Broder, K. N. Bossart, Kai Xu, 2012, Current topics in microbiology and immunology.

A treatment for and vaccine against the deadly Hendra and Nipah viruses.

C. Broder, D. Dimitrov, Zhongyu Zhu, 2013, Antiviral research.

Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly

C. Broder, Z. Zhou, G. Skiniotis, 2015, PLoS pathogens.

Biochemical, Conformational, and Immunogenic Analysis of Soluble Trimeric Forms of Henipavirus Fusion Glycoproteins

C. Broder, G. Skiniotis, Min Lu, 2012, Journal of Virology.

Host cell recognition by the henipaviruses: Crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3

Kai Xu, C. Broder, K. Rajashankar, 2008, Proceedings of the National Academy of Sciences.

Myristoylation of the fus1 protein is required for tumor suppression in human lung cancer cells.

J. Minna, J. Roth, E. Atkinson, 2004, Cancer research.

miRNA-9 Inhibits Proliferation and Migration of Lung Squamous Cell Carcinoma Cells by Regulating NRSF/EGFR

Kai Xu, Yongtao Han, X. Leng, 2020, Technology in cancer research & treatment.

New Insights into the Hendra Virus Attachment and Entry Process from Structures of the Virus G Glycoprotein and Its Complex with Ephrin-B2

C. Broder, K. Rajashankar, Kai Xu, 2012, PloS one.

Architecture of Eph receptor clusters

P. W. Janes, M. Lackmann, J. Walker, 2010, Proceedings of the National Academy of Sciences.

A novel interplay between HOTAIR and DNA methylation in osteosarcoma cells indicates a new therapeutic strategy

Xia Li, Kai Xu, M. He, 2017, Journal of Cancer Research and Clinical Oncology.

Identification of serum biomarkers for ovarian cancer using MALDI–TOF-MS combined with magnetic beads

Jun Zhang, Kai Xu, Xinyou Xie, 2012, International Journal of Clinical Oncology.

Site occupancy and glycan compositional analysis of two soluble recombinant forms of the attachment glycoprotein of Hendra virus.

Kai Xu, Michelle L Colgrave, C. Broder, 2012, Glycobiology.

Eph/ephrin recognition and the role of Eph/ephrin clusters in signaling initiation.

Kai Xu, D. Nikolov, J. Himanen, 2013, Biochimica et biophysica acta.

An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth

S. Rafii, U. Kusebauch, R. Moritz, 2016, The Journal of experimental medicine.

Purification and functional assessment of smooth muscle cells derived from mouse embryonic stem cells

J. Tao, Chenghui Yan, Ya‐Ling Han, 2013, Journal of geriatric cardiology : JGC.

Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5

Y. Goldgur, Kai Xu, D. Nikolov, 2013, Proceedings of the National Academy of Sciences.

The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation

M. Tessier-Lavigne, Kai Xu, D. Nikolov, 2015, Genes & development.

Correlations of breast cancer FHIT gene with the incidence and prognosis of breast cancer.

Yu Fu, Kai Xu, Wenqing Song, 2019, Journal of B.U.ON. : official journal of the Balkan Union of Oncology.

Retrovirus–mediated wild–type P53 gene transfer to tumors of patients with lung cancer.

W. Hong, J. Roth, J. Lee, 1996, Nature Medicine.

Enhancement of antitumor activity of cisplatin in human lung cancer cells by tumor suppressor FUS1

J. Roth, L. Ji, Kai Xu, 2008, Cancer Gene Therapy.

The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism

M. Dalva, Kai Xu, D. Nikolov, 2021, International journal of molecular sciences.