K. Iles

发表

Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species

S. Matalon, Gang Liu, A. Lazrak, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Heat-shock Response Increases Lung Injury Caused by Pseudomonas aeruginosa via an Interleukin-10-dependent Mechanism in Mice

J. Pittet, J. Ricci, K. Iles, 2014, Anesthesiology.

Activation of the Heat Shock Response Attenuates the Interleukin 1&bgr;–Mediated Inhibition of the Amiloride-Sensitive Alveolar Epithelial Ion Transport

J. Pittet, M. Matthay, K. Iles, 2013, Shock.

Fatty acid transduction of nitric oxide signaling: nitrolinoleic acid mediates protective effects through regulation of the ERK pathway.

Marcienne M Wright, M. P. Cole, M. Matthay, 2009, Free radical biology & medicine.

Glutathione suppresses TGF-beta-induced PAI-1 expression by inhibiting p38 and JNK MAPK and the binding of AP-1, SP-1, and Smad to the PAI-1 promoter.

K. Iles, A. Yi, P. Vayalil, 2007, American journal of physiology. Lung cellular and molecular physiology.

AP-1 activation through endogenous H(2)O(2) generation by alveolar macrophages.

H. Forman, T. Iwamoto, K. Iles, 2002, Free radical biology & medicine.

Macrophage signaling and respiratory burst

H. Forman, K. Iles, 2002, Immunologic research.

Analysis of transcription factor remodeling in phase II gene expression with curcumin.

H. Forman, K. Iles, D. Dickinson, 2004, Methods in enzymology.

Fatty acid transduction of nitric oxide signaling: nitrolinoleic acid potently activates endothelial heme oxygenase 1 expression.

Marcienne M Wright, B. Freeman, K. Iles, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Fatty Acid Transduction of Nitric Oxide Signaling

Y. Chen, B. Freeman, B. Branchaud, 2005, Journal of Biological Chemistry.

Reactive species and pulmonary edema

S. Matalon, K. Iles, D. Dickinson, 2009, Expert review of respiratory medicine.

Title IL-8 inhibits cAMP-stimulated alveolar epithelial fluid transport via a GRK 2 / PI 3 K-dependent mechanism

J. Pittet, M. Matthay, L. Ware, 2013 .

IL‐8 inhibits cAMP‐stimulated alveolar epithelial fluid transport via a GRK2/PI3K‐dependent mechanism

J. Pittet, M. Matthay, L. Ware, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A549 subclones demonstrate heterogeneity in toxicological sensitivity and antioxidant profile.

Hongqiao Zhang, H. Forman, K. Iles, 2002, American journal of physiology. Lung cellular and molecular physiology.

Variable regulation of glutamate cysteine ligase subunit proteins affects glutathione biosynthesis in response to oxidative stress.

H. Forman, T. Kavanagh, K. Iles, 2004, Archives of biochemistry and biophysics.

4-hydroxynonenal induces glutamate cysteine ligase through JNK in HBE1 cells.

Hongqiao Zhang, H. Forman, T. Iwamoto, 2002, Free radical biology & medicine.

HNE increases HO-1 through activation of the ERK pathway in pulmonary epithelial cells.

H. Forman, K. Iles, D. Dickinson, 2005, Free radical biology & medicine.

HMGB1 Accelerates Alveolar Epithelial Repair via an IL-1β- and αvβ6 Integrin-dependent Activation of TGF-β1

J. Pittet, M. Matthay, Xiaohui Fang, 2013, PloS one.

Curcumin alters EpRE and AP‐1 binding complexes and elevates glutamate‐cysteine ligase gene expression

Hongqiao Zhang, H. Forman, K. Iles, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cytoprotection against Oxidative Stress and the Regulation of Glutathione Synthesis

H. Forman, V. Darley-Usmar, K. Iles, 2003, Biological chemistry.

Chronic ethanol feeding increases the quantity of Gαs‐protein in rat liver plasma membranes

K. Iles, L. Nagy, 1995 .

Chronic ethanol feeding increases the quantity of G alpha s-protein in rat liver plasma membranes.

K. Iles, L. Nagy, 1995, Hepatology.

PAI-1 is an essential component of the pulmonary host response during Pseudomonas aeruginosa pneumonia in mice

J. Pittet, Yuanlin Song, K. Iles, 2011, Thorax.

THORAXJNL155788-200111 788..796

J. Pittet, K. Iles, M. Howard, 2011 .

HMGB 1 Accelerates Alveolar Epithelial Repair via an IL-1 band a v b 6 Integrin-dependent Activation of TGF-b 1

J. Pittet, M. Matthay, Xiaohui Fang, 2013 .

HNE--signaling pathways leading to its elimination.

H. Forman, K. Iles, D. Dickinson, 2003, Molecular aspects of medicine.

lungsfluid clearance in ex vivo rat and guinea pig -adrenergic agonist, increases

J. Pittet, M. Matthay, L. Ware, 2015 .

Stroke‐induced activation of the α7 nicotinic receptor increases Pseudomonas aeruginosa lung injury

R. Giffard, J. Pittet, K. Iles, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The Adp-stimulated Nadph Oxidase Activates The Ask-1/mkk4/jnk Pathway In Alveolar Macrophages

Hongqiao Zhang, H. Forman, G. Merrill, 2006, Free radical research.

Activation of the mitochondrial caspase cascade in the absence of protein synthesis does not require c-Jun N-terminal kinase.

H. Forman, T. Iwamoto, K. Iles, 2002, Archives of biochemistry and biophysics.

Cytoprotective-selective activated protein C attenuates Pseudomonas aeruginosa-induced lung injury in mice.

José A Fernández, M. Cohen, J. Griffin, 2011, American journal of respiratory cell and molecular biology.

Mechanisms of glutamate cysteine ligase (GCL) induction by 4-hydroxynonenal.

K. Iles, Rui-ming Liu, 2005, Free radical biology & medicine.

4-Hydroxynonenal induces rat gamma-glutamyl transpeptidase through mitogen-activated protein kinase-mediated electrophile response element/nuclear factor erythroid 2-related factor 2 signaling.

Hongqiao Zhang, H. Forman, K. Iles, 2006, American journal of respiratory cell and molecular biology.

Environmental Health: Overview

K. Iles, D. Dickinson, 2017 .

IL-8 Inhibits cAMP-Stimulated Alveolar Epithelial Fluid Transport Via a GRK2/PI3K-Dependent Mechanism.

J. Pittet, M. Matthay, L. Ware, 2009, ATS 2009.