S. Krawczyk

发表

Inhibition of Respiratory Syncytial Virus Fusion by the Small Molecule VP-14637 via Specific Interactions with F Protein

T. Cihlar, J. Douglas, M. Panis, 2003, Journal of Virology.

Small Molecules VP-14637 and JNJ-2408068 Inhibit Respiratory Syncytial Virus Fusion by Similar Mechanisms

T. Cihlar, J. Douglas, M. Panis, 2005, Antimicrobial Agents and Chemotherapy.

The tertiary structure of a DNA aptamer which binds to and inhibits thrombin determines activity.

N Bischofberger, S. Swaminathan, P. Bolton, 1993, Biochemistry.

An anti-parallel triple helix motif with oligodeoxynucleotides containing 2'-deoxyguanosine and 7-deaza-2'-deoxyxanthosine.

S. Krawczyk, J. Milligan, M. Matteucci, 1993, Nucleic acids research.

Synthesis of 4-Substituted Imidazo[4,5-d][1,2,3]triazine (2-Azapurine)nucleosides

S. Krawczyk, M. Migawa, L. Townsend, 2000, Nucleosides, nucleotides & nucleic acids.

Preclinical Characterization of GS-9669, a Thumb Site II Inhibitor of the Hepatitis C Virus NS5B Polymerase

S. Leavitt, T. Appleby, M. Fenaux, 2012, Antimicrobial Agents and Chemotherapy.

Chapter 14. Non-HIV Antiviral Agents

S. Krawczyk, N. Bischofberger, 1997 .

Triple helix formation inhibits transcription elongation in vitro.

S. Krawczyk, J. Toole, M. Matteucci, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus

S. Krawczyk, R. Nassiri, L. Townsend, 1987, Antimicrobial Agents and Chemotherapy.

2′,3′-Dideoxyadenosine Analogs of the Nucleoside Antibiotics Tubercidin, Toyocamycin and Sangivamycin

S. Krawczyk, L. Townsend, 1989 .

A total synthesis of the naturally occurring pyrrolo[2,3-]pyrimidine nucleoside, mycalisine A

S. Krawczyk, L. Townsend, E. Meade, 1988 .

Synthesis of the new ring system, Pyrazolo[3,4‐d][1,3]diazepine. A novel route for the synthesis of azolo[1,3]diazepines

S. Krawczyk, L. Townsend, O. Acevedo, 1985 .

N2- and C8-substituted oligodeoxynucleotides with enhanced thrombin inhibitory activity in vitro and in vivo.

J. Dougherty, S. Krawczyk, S. Swaminathan, 1998, Journal of medicinal chemistry.

Synthesis and antiproliferative and antiviral activity of 2'-deoxy-2'-fluoroarabinofuranosyl analogs of the nucleoside antibiotics toyocamycin and sangivamycin.

R. Ptak, S. Krawczyk, M. Nassiri, 1995, Journal of medicinal chemistry.

Arabinofuranosylpyrrolo[2,3-d]pyrimidines as potential agents for human cytomegalovirus infections.

S. Krawczyk, M. Nassiri, E. Kern, 1990, Journal of medicinal chemistry.

Total synthesis of (4R)- and (4S)-5,6-dihydro-1-.beta.-D-ribofuranosyl-4H-pyrazolo[3,4-d][1,3]diazepin-4-ol and (8R)- and (8S)-7,8-dihydro-3-.beta.-D-ribofuranosyl-6H-v-triazolo[4,5-d][1,3]diazepin-8-ol: two heterocyclic analogs of the nucleoside antibiotic coformycin

S. Krawczyk, L. Townsend, O. Acevedo, 1986 .

A Total Synthesis of the Naturally Occurring Pyrrolo(2,3-d)pyrimidine Nucleoside, Mycalisine A (I).

S. Krawczyk, L. Townsend, E. Meade, 1989 .

Rapid communication: Inhibition of adenosine deaminase by azapurine ribonucleosides

S. Krawczyk, D. Shewach, L. Townsend, 1992 .

Specific, high-efficiency, triple-helix-mediated cross-linking to duplex DNA

J. Shaw, S. Krawczyk, M. Matteucci, 1991 .

Oligonucleotide-mediated triple helix formation using an N3-protonated deoxycytidine analog exhibiting pH-independent binding within the physiological range.

B. Froehler, S. Krawczyk, J. Milligan, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Antagonism of the cytotoxic but not antiviral effects of ara-sangivamycin by adenosine

S. Krawczyk, L. Townsend, J. Drach, 1989, Antimicrobial Agents and Chemotherapy.

Synthesis and evaluation of certain thiosangivamycin analogs as potential inhibitors of cell proliferation and human cytomegalovirus.

S. Krawczyk, M. Nassiri, T. Renau, 1995, Journal of medicinal chemistry.

A novel approach towards the synthesis of the 3,4,5-trihydro-1,3-diazepin-5-ol ring structure

S. Krawczyk, L. Townsend, O. Acevedo, 1983 .

Total Synthesis of (4R)- and (4S)-5,6-Dihydro-1-β-D-ribofuranosyl-4H- pyrazolo[3,4-d][1,3]diazepin-4-ol (Ia) and (Ib) and of (8R)- and (8S)- 7,8-Dihydro-3-β-D-ribofuranosyl-6H-v-triazolo[4,5-d][1,3]diazepin-8-ol (Ic) and (Id): Two Het

S. Krawczyk, L. Townsend, O. Acevedo, 1986 .

X-Ray and1H NMR Analyses of the Structure and Conformation of 2-Azacoformycin, a Potent Inhibitor of Adenosine Deaminase.

J. Brisson, S. Krawczyk, G. Birnbaum, 1986 .

Correction. X--ray and (1)H NMR Analyses of the Structure and Conformation of 2-Azacoformycin, a Potent Inhibitor or Adenosine Deaminase.

J. Brisson, S. Krawczyk, G. Birnbaum, 1985, Journal of the American Chemical Society.

Preclinical Characterization of the Novel Hepatitis C Virus NS3 Protease Inhibitor GS-9451

H. Mo, Huiling Yang, W. Delaney, 2013, Antimicrobial Agents and Chemotherapy.

Specific Interactions with F Protein Fusion by the Small Molecule VP-14637 via Inhibition of Respiratory Syncytial Virus

T. Cihlar, J. Douglas, M. Panis, 2003 .

Inhibition of HIV-1 RNase H Activity by Nucleotide Dimers and Monomers

J. Cherrington, S. Krawczyk, N. Bischofberger, 1996 .

Potassium-resistant triple helix formation and improved intracellular gene targeting by oligodeoxyribonucleotides containing 7-deazaxanthine.

P. Glazer, S. Krawczyk, A. Faruqi, 1997, Nucleic acids research.

Synthesis of a pyrido[1,2-a]purine nucleoside by a novel ring cleavage-annulation reaction of 3-β-D-ribofuranosylimidazo-[4,5-d]--triazin-4-one

S. Krawczyk, L. Townsend, 1991 .

Synthesis of a Pyrido(1,2-a)purine Nucleoside by a Novel Ring Cleavage. Annulation Reaction of 3-β-D-Ribofuranosylimidazo(4,5-d)-v- triazin-4-one.

S. Krawczyk, L. Townsend, 1992 .

Structure-Activity Study of Oligodeoxynucleotides Which Inhibit Thrombin

S. Krawczyk, S. Swaminathan, L. Griffin, 1995 .