Z. Ambrose

发表

Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay

Jeremy Luban, J. Luban, C. Aiken, 2013, Retrovirology.

Direct visualization of HIV-1 with correlative live-cell microscopy and cryo-electron tomography.

Gregory A Gibson, Peijun Zhang, Karl Debiec, 2011, Structure.

Track A Basic Science

S. Sugden, D. Hazuda, F. Pereyra, 2012, Journal of the International AIDS Society.

Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis.

A. Engelman, C. Aiken, J. Perilla, 2020, PLoS biology.

Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis

A. Engelman, C. Aiken, J. Perilla, 2020, bioRxiv.

A Novel Phenotype Links HIV-1 Capsid Stability to cGAS-Mediated DNA Sensing

G. Melikyan, C. Aiken, M. Yamashita, 2019, Journal of Virology.

Truncated CPSF6 Forms Higher-Order Complexes That Bind and Disrupt HIV-1 Capsid

Simon C Watkins, Peijun Zhang, G. Harris, 2018, Journal of Virology.

Interferon-Inducible CD169/Siglec1 Attenuates Anti-HIV-1 Effects of Alpha Interferon

Simon C Watkins, G. Gibson, Z. Ambrose, 2017, Journal of Virology.

The Level of Reverse Transcriptase (RT) in Human Immunodeficiency Virus Type 1 Particles Affects Susceptibility to Nonnucleoside RT Inhibitors but Not to Lamivudine

P. Boyer, S. Hughes, V. KewalRamani, 2006, Journal of Virology.

Construction and characterization of two SARS‐CoV‐2 minigenome replicon systems

P. Moore, Z. Ambrose, Haitao Guo, 2022, Journal of medical virology.

Of mice and monkeys: new advances in animal models to study HIV-1 therapy and prophylaxis

V. KewalRamani, Z. Ambrose, V. Kewalramani, 2008 .

Evidence for Early Local Viral Replication and Local Production of Antiviral Immunity upon Mucosal Simian-Human Immunodeficiency Virus SHIV89.6 Infection in Macaca nemestrina

Shiu-Lok Hu, Z. Ambrose, E. Finn, 2001, Journal of Virology.

HIV/AIDS: in search of an animal model.

P. Bieniasz, V. KewalRamani, Z. Ambrose, 2007, Trends in biotechnology.

Two Coselected Distal Mutations in HIV-1 Reverse Transcriptase (RT) Alter Susceptibility to Nonnucleoside RT Inhibitors and Nucleoside Analogs

P. Boyer, P. Clark, S. Hughes, 2019, Journal of Virology.

Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.

N. Sluis-Cremer, Z. Ambrose, N. Hamamouch, 2007, The Biochemical journal.

The Human Immunodeficiency Virus Type 1 Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutation I132M Confers Hypersensitivity to Nucleoside Analogs

B. Herman, N. Sluis-Cremer, Z. Ambrose, 2009, Journal of Virology.

Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4 (cid:2) T Cells In Vitro

Simon C Watkins, A. Engelman, Erik Serrao, 2016 .

Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner

Simon C Watkins, A. Engelman, M. Bruchez, 2020, mBio.

Targeting Spike Glycans to Inhibit SARS-CoV2 Viral Entry

A. Gronenborn, D. Yang, R. Baric, 2022, bioRxiv.

Evidence for immune-mediated reduction of viral replication in Macaca nemestrina mucosally immunized with inactivated SHIV(89.6).

D. Montefiori, Shiu-Lok Hu, Z. Ambrose, 2003, Virology.

Rilpivirine analogs potently inhibit drug-resistant HIV-1 mutants

S. Hughes, Steven J Smith, D. Maloney, 2016, Retrovirology.

A macaque model of HIV-1 infection

Ronald S Veazey, P. Bieniasz, J. Lifson, 2009, Proceedings of the National Academy of Sciences.

The nucleoside analogs 4'C-methyl thymidine and 4'C-ethyl thymidine block DNA synthesis by wild-type HIV-1 RT and excision proficient NRTI resistant RT variants.

P. Boyer, S. Hughes, Z. Ambrose, 2007, Journal of molecular biology.

The nucleoside analogue D-carba T blocks HIV-1 reverse transcription.

P. Boyer, S. Hughes, Chenzhong Liao, 2009, Journal of medicinal chemistry.

Long-Acting Rilpivirine (RPV) Preexposure Prophylaxis Does Not Inhibit Vaginal Transmission of RPV-Resistant HIV-1 or Select for High-Frequency Drug Resistance in Humanized Mice

B. Keele, K. Shutt, P. Pennings, 2020, Journal of Virology.

Use of Animal Models for Anti-HIV Drug Development

Z. Ambrose, 2012 .

APOBEC3 selects V179I in HIV-1 reverse transcriptase to provide selective advantage for non-nucleoside reverse transcriptase inhibitor-resistant mutants

Z. Ambrose, C. Kline, D. Fischer, 2022, Frontiers in Virology.

Low Frequency of Drug-Resistant Variants Selected by Long-Acting Rilpivirine in Macaques Infected with Simian Immunodeficiency Virus Containing HIV-1 Reverse Transcriptase

J. Mellors, Z. Ambrose, C. Kline, 2015, Antimicrobial Agents and Chemotherapy.

In Vitro Characterization of a Simian Immunodeficiency Virus-Human Immunodeficiency Virus (HIV) Chimera Expressing HIV Type 1 Reverse Transcriptase To Study Antiviral Resistance in Pigtail Macaques

S. Hughes, J. Coffin, V. KewalRamani, 2004, Journal of Virology.

Resistance in Pigtail Macaques Transcriptase To Study Antiviral Expressing HIV Type 1 Reverse Immunodeficiency Virus ( HIV ) Chimera Immunodeficiency Virus-Human In Vitro Characterization of a Simian

S. Hughes, J. Coffin, V. KewalRamani, 2004 .

Human Immunodeficiency Virus Type 1 Capsid Mutation N74D Alters Cyclophilin A Dependence and Impairs Macrophage Infection

A. Engelman, S. Hughes, T. Takemura, 2012, Journal of Virology.

Flexible use of nuclear import pathways by HIV-1.

A. Engelman, J. Sodroski, S. Hughes, 2010, Cell host & microbe.

Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro

Simon C Watkins, A. Engelman, Erik Serrao, 2016, Journal of Virology.

Rilpivirine and Doravirine Have Complementary Efficacies Against NNRTI-Resistant HIV-1 Mutants

S. Hughes, J. Schneider, Z. Ambrose, 2016, Journal of acquired immune deficiency syndromes.

A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host

D. Petrov, B. Keele, Shiu-Lok Hu, 2017, PLoS pathogens.

Identification of HIV inhibitors guided by free energy perturbation calculations.

Orlando Acevedo, O. Acevedo, Z. Ambrose, 2012, Current pharmaceutical design.

Incomplete Protection against Simian Immunodeficiency Virus Vaginal Transmission in Rhesus Macaques by a Topical Antiviral Agent Revealed by Repeat Challenges

J. Lifson, W. Alvord, D. Lu, 2008, Journal of Virology.

Disassembling the Nature of Capsid: Biochemical, Genetic, and Imaging Approaches to Assess HIV-1 Capsid Functions

Z. Ambrose, D. Fischer, Z. Ingram, 2021, Viruses.

HIV-1 uncoating: connection to nuclear entry and regulation by host proteins.

C. Aiken, Z. Ambrose, 2014, Virology.

Ultrasensitive Allele-Specific PCR Reveals Rare Preexisting Drug-Resistant Variants and a Large Replicating Virus Population in Macaques Infected with a Simian Immunodeficiency Virus Containing Human Immunodeficiency Virus Reverse Transcriptase

J. Mellors, J. Coffin, V. KewalRamani, 2012, Journal of Virology.

Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy

J. Mellors, J. Coffin, Z. Ambrose, 2015, Retrovirology.

Genetic Diversity of Simian Immunodeficiency Virus Encoding HIV-1 Reverse Transcriptase Persists in Macaques despite Antiretroviral Therapy

J. Lifson, J. Mellors, J. Coffin, 2010, Journal of Virology.

RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy

Wei Shao, R. Stephens, J. Lifson, 2009, Retrovirology.

Suppression of Viremia and Evolution of Human Immunodeficiency Virus Type 1 Drug Resistance in a Macaque Model for Antiretroviral Therapy

J. Lifson, J. Mellors, J. Coffin, 2007, Journal of Virology.

High resolution spatio-temporal assessment of simian / human immunodeficiency virus ( SHIV ) evolution reveals a highly dynamic process within the host Authors :

D. Petrov, B. Keele, Shiu-Lok Hu, 2017 .

CA Mutation N57A Has Distinct Strain-Specific HIV-1 Capsid Uncoating and Infectivity Phenotypes

Simon C Watkins, M. Yamashita, Z. Ambrose, 2019, Journal of Virology.

Dysregulation of multiple inflammatory molecules in lymph node and ileum of macaques during RT‐SHIV infection with or without antiretroviral therapy

Shiu-Lok Hu, Z. Ambrose, C. Kline, 2014, Journal of medical primatology.

Persistence of Viral Reservoirs in Multiple Tissues after Antiretroviral Therapy Suppression in a Macaque RT-SHIV Model

J. Lifson, J. Mellors, M. Piatak, 2013, PLoS ONE.

CG Dinucleotide Removal in Bioluminescent and Fluorescent Reporters Improves HIV-1 Replication and Reporter Gene Expression for Dual Imaging in Humanized Mice

Z. Ambrose, C. Kline, C. N. Roy, 2021, Journal of virology.

SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis

S. Fortune, J. Flynn, Z. Ambrose, 2020, bioRxiv.

Visualization and quantification of simian immunodeficiency virus-infected cells using non-invasive molecular imaging.

Z. Ambrose, Jiasheng Song, C. Anderson, 2015, The Journal of general virology.

AutoCLEM: An Automated Workflow for Correlative Live-Cell Fluorescence Microscopy and Cryo-Electron Tomography

Peijun Zhang, Z. Ambrose, J. Ning, 2019, Scientific Reports.

RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy

R. Stephens, J. Lifson, J. Mellors, 2009, Retrovirology.

Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro

Simon C Watkins, A. Engelman, Erik Serrao, 2016, Journal of Virology.

SIV Evolutionary Dynamics in Cynomolgus Macaques during SIV-Mycobacterium tuberculosis Co-Infection

P. Pennings, Z. Ambrose, P. Lin, 2021, Viruses.

Dysregulation of multiple inflammatory molecules in lymph node and ileum of macaques during RT‐SHIV infection with or without antiretroviral therapy

Shiu-Lok Hu, Z. Ambrose, C. Kline, 2014, Journal of medical primatology.

High resolution spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host

D. Petrov, B. Keele, Shiu-Lok Hu, 2017, bioRxiv.

Direct visualization of HIV-1 with correlative live-cell microscopy and cryo-electron tomography.

Simon C Watkins, Karl T. Debiec, Peijun Zhang, 2011, Structure.

Rilpivirine analogs potently inhibit drug-resistant HIV-1 mutants

S. Hughes, D. Maloney, Z. Ambrose, 2016, Retrovirology.