V. Géli

发表

ZZW-115–dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents

O. Abián, A. Velázquez‐Campoy, J. Iovanna, 2020, JCI insight.

Nuclear dynamics of the Set1C subunit Spp1 prepares meiotic recombination sites for break formation

F. Klein, Doris Chen, V. Géli, 2018, The Journal of cell biology.

Inactivation of Ku-Mediated End Joining Suppresses mec1Δ Lethality by Depleting the Ribonucleotide Reductase Inhibitor Sml1 through a Pathway Controlled by Tel1 Kinase and the Mre11 Complex

J. Haber, V. Géli, Y. Corda, 2005, Molecular and Cellular Biology.

The multiple faces of Set1.

V. Géli, P. Dehé, Vincent Géli, 2006, Biochemistry and cell biology = Biochimie et biologie cellulaire.

How telomeres are replicated

E. Gilson, V. Géli, 2007, Nature Reviews Molecular Cell Biology.

Recognition of the colicin A N-terminal epitope 1C11 in vitro and in vivo in Escherichia coli by its cognate monoclonal antibody.

R. Lloubès, V. Géli, C. Lazdunski, 1993, FEMS microbiology letters.

DNA damage response to eroded telomeres

V. Géli, M. Lisby, 2009, Cell cycle.

Cdc13 at a crossroads of telomerase action

V. Géli, Y. Corda, D. Churikov, 2013, Front. Oncol..

Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions

E. Gilson, V. Géli, Y. Corda, 1999, Nature Genetics.

The set1Delta mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes.

G. Lucchini, E. Gilson, V. Géli, 2001, Genes & development.

Coordination of Cell Cycle Progression and Mitotic Spindle Assembly Involves Histone H3 Lysine 4 Methylation by Set1/COMPASS

T. Margaritis, F. Holstege, M. Kalanon, 2016, Genetics.

Integration of the colicin A pore-forming domain into the cytoplasmic membrane of Escherichia coli.

V. Géli, D. Duché, Y. Corda, 1999, Journal of molecular biology.

Functional domains of colicin A

F. Pattus, V. Géli, C. Lazdunski, 1988, Molecular microbiology.

Comparison of the uptake systems for the entry of various BtuB group colicins into Escherichia coli.

R. Lloubès, V. Géli, C. Lazdunski, 1989, Journal of general microbiology.

The fission yeast Stn1-Ten1 complex limits telomerase activity via its SUMO-interacting motif and promotes telomeres replication

V. Géli, Toru M. Nakamura, S. Coulon, 2018, Science Advances.

Telomerase Repairs Collapsed Replication Forks at Telomeres.

V. Géli, S. Lambert, S. Coulon, 2020, Cell reports.

RPA prevents G‐rich structure formation at lagging‐strand telomeres to allow maintenance of chromosome ends

Y. Gachet, V. Géli, C. Saintomé, 2015, The EMBO journal.

The COMPASS Subunit Spp1 Links Histone Methylation to Initiation of Meiotic Recombination

A. Nicolas, V. Géli, Laurent Acquaviva, 2013, Science.

Molecular Mechanism of Action of Pore-Forming Colicins and of their Immunity Proteins

R. Lloubès, F. Pattus, V. Géli, 1992 .

Yra1-bound RNA–DNA hybrids cause orientation-independent transcription–replication collisions and telomere instability

J. F. Ruiz, V. Géli, M. Simon, 2018, Genes & development.

UFMylation of MRE11 is essential for telomere length maintenance and hematopoietic stem cell survival

M. Cayuela, S. Audebert, L. Camoin, 2021, Science advances.

UFMylation of MRE11 is essential for maintenance of telomere length and hematopoietic stem cell survival

M. Cayuela, S. Audebert, L. Camoin, 2019, bioRxiv.

Set1- and Clb5-deficiencies disclose the differential regulation of centromere and telomere dynamics in Saccharomyces cerevisiae meiosis

H. Scherthan, V. Géli, J. Sollier, 2005, Journal of Cell Science.

Two Distinct Repressive Mechanisms for Histone 3 Lysine 4 Methylation through Promoting 3′-End Antisense Transcription

J. Benschop, T. Margaritis, N. Brabers, 2012, PLoS genetics.

Protein Interactions within the Set1 Complex and Their Roles in the Regulation of Histone 3 Lysine 4 Methylation*

Lorena E Rosaleny, A. Shevchenko, A. Shevchenko, 2006, Journal of Biological Chemistry.

STEEx, a boundary between the world of quiescence and the vegetative cycle

V. Géli, S. Coulon, Laetitia Maestroni, 2018, Current Genetics.

Subtelomeric proteins negatively regulate telomere elongation in budding yeast

E. Gilson, R. Wellinger, V. Géli, 2006, The EMBO journal.

RPA regulates telomerase action by providing Est1p access to chromosome ends

E. Gilson, V. Géli, Y. Corda, 2004, Nature Genetics.

TOP3A amplification and ATRX inactivation are mutually exclusive events in pediatric osteosarcomas using ALT

F. Bertucci, D. Birnbaum, H. Pickett, 2022, EMBO molecular medicine.

A two-step model for senescence triggered by a single critically short telomere

E. Gilson, K. Sawamoto, G. Raposo, 2010, Nature Cell Biology.

Telomeric C‐circles localize at nuclear pore complexes in Saccharomyces cerevisiae

V. Géli, M. Simon, Marion Dubarry, 2022, The EMBO journal.

Construction of phoE-caa, a novel PCR- and immunologically detectable marker gene for Pseudomonas putida

J. Tommassen, B. Lugtenberg, V. Géli, 1994, Applied and environmental microbiology.

Immunity proteins to pore‐forming colicins: structure‐function relationships

V. Géli, C. Lazdunski, D. Espesset, 1994, Molecular microbiology.

Inherited human Apollo deficiency causes severe bone marrow failure and developmental defects

Yehuda, É. Lainey, I. Callebaut, 2021 .

Induction of telomerase in p21-positive cells counteracts capillaries rarefaction in aging mice lung

E. Gilson, G. Giovinazzo, V. Géli, 2022, bioRxiv.

The finger subdomain of yeast telomerase cooperates with Pif1p to limit telomere elongation

E. Gilson, J. Lingner, A. Pollice, 2006, Nature Structural &Molecular Biology.

Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue

Shondra M. Pruett-Miller, J. Rosenfeld, M. Boerries, 2021, Blood.

RPA facilitates telomerase activity at chromosome ends in budding and fission yeasts

E. Gilson, V. Géli, M. Simon, 2012, The EMBO journal.

Acidic interaction of the colicin A pore-forming domain with model membranes of Escherichia coli lipids results in a large perturbation of acyl chain order and stabilization of the bilayer.

J. Killian, V. Géli, R. Demel, 1992, Biochemistry.

Functional reconstitution in Escherichia coli of the yeast mitochondrial matrix peptidase from its two inactive subunits.

V. Géli, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Mitochondrial protein import

V. Géli, B. Glick, 1990, Journal of bioenergetics and biomembranes.

The MAS-encoded processing protease of yeast mitochondria. Overproduction and characterization of its two nonidentical subunits.

Meijia Yang, A. Lustig, V. Géli, 1990, The Journal of biological chemistry.

Analysis of Recombination at Yeast Telomeres.

V. Géli, M. Simon, D. Churikov, 2021, Methods in molecular biology.

A proto-telomere is elongated by telomerase in a shelterin-dependent manner in quiescent fission yeast cells

V. Géli, K. Runge, S. Coulon, 2022, Nucleic acids research.

The channel domain of colicin A is inhibited by its immunity protein through direct interaction in the Escherichia coli inner membrane.

V. Géli, D. Duché, D. Baty, 1996, The EMBO journal.

The mitochondrial processing peptidase: Function and specificity

V. Géli, P. Luciano, 1996, Experientia.

Insertion of proteins into membranes. A survey.

V. Géli, H. Bénédetti, 1994, Sub-cellular biochemistry.

Import of Colicins into Escherichia Coli

R. Lloubès, J. Pagés, V. Géli, 1992 .

Extracellular release of colicin A is non‐specific.

R. Lloubès, V. Géli, C. Lazdunski, 1987, The EMBO journal.

Cleavage of colicin D is necessary for cell killing and requires the inner membrane peptidase LepB.

L. Mora, R. Buckingham, V. Géli, 2001, Molecular cell.

Modeling Heterogeneity of Triple‐Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance

G. Mills, Ulrike A. Köhler, S. Lev, 2020, bioRxiv.

Modeling heterogeneity of Triple-Negative Breast Cancer highlights potency of WEE1 and BCL-XL targeting

G. Mills, S. Lev, Fabrice Daian, 2020 .

Histone H3 lysine 4 trimethylation marks meiotic recombination initiation sites

Alain Nicolas, Nicolas Robine, A. Nicolas, 2009, The EMBO journal.

Methylation of H3 Lysine 4 at Euchromatin Promotes Sir3p Association with Heterochromatin*

Tony Kouzarides, Andrew J. Bannister, T. Kouzarides, 2004, Journal of Biological Chemistry.

MRX Increases Chromatin Accessibility at Stalled Replication Forks to Promote Nascent DNA Resection and Cohesin Loading.

M. Skrzypczak, K. Ginalski, Ismael Padioleau, 2019, Molecular cell.

High levels of histones promote whole-genome-duplications and trigger a Swe1WEE1-dependent phosphorylation of Cdc28CDK1

M. Mendoza, S. Chávez, X. Peñate, 2018, eLife.

High levels of histones promote whole- genome-duplications and trigger a Swe1-dependent phosphorylation of Cdc28

M. Mendoza, S. Chávez, X. Peñate, 2018 .

The Set1 N-terminal domain and Swd2 interact with RNA polymerase II CTD to recruit COMPASS

H. Bae, S. Buratowski, L. M. Soares, 2020, Nature Communications.

The number of vertebrate repeats can be regulated at yeast telomeres by Rap1‐independent mechanisms

E. Gilson, F. Ascenzioni, V. Géli, 2003, The EMBO journal.

Binding to RNA regulates Set1 function

D. Libri, V. Géli, T. Candelli, 2017, Cell Discovery.

RPA and Pif1 cooperate to remove G-rich structures at both leading and lagging strand

V. Géli, Y. Corda, S. Coulon, 2020, Cell stress.

Eroded telomeres are rearranged in quiescent fission yeast cells through duplications of subtelomeric sequences

V. Géli, B. Arcangioli, S. Coulon, 2017, Nature Communications.

The fission yeast spSet1p is a histone H3-K4 methyltransferase that functions in telomere maintenance and DNA repair in an ATM kinase Rad3-dependent pathway.

F. Ishikawa, V. Géli, S. Francesconi, 2003, Journal of molecular biology.

Spp1 at the crossroads of H3K4me3 regulation and meiotic recombination

V. Géli, Laurent Acquaviva, P. Dehé, 2013, Epigenetics.

Set1 is required for meiotic S‐phase onset, double‐strand break formation and middle gene expression

Karsten Suhre, Alain Nicolas, C. Soustelle, 2004, The EMBO journal.

The telomerase cycle: normal and pathological aspects

E. Gilson, V. Géli, P. Luciano, 2005, Journal of Molecular Medicine.

p53/p21 pathway activation contributes to the ependymal fate decision downstream of GemC1.

F. Causeret, N. Spassky, C. Blugeon, 2022, Cell reports.

FACT Prevents the Accumulation of Free Histones Evicted from Transcribed Chromatin and a Subsequent Cell Cycle Delay in G1

S. Chávez, A. Gunjan, V. Géli, 2010, PLoS genetics.

Non-canonical Roles of Telomerase: Unraveling the Imbroglio

E. Ségal-Bendirdjian, V. Géli, 2019, Front. Cell Dev. Biol..

Nuclear Pore Complexes in DNA Repair and Telomere Maintenance

E. Soutoglou, C. Dargemont, V. Géli, 2018 .

CST meets shelterin to keep telomeres in check.

E. Gilson, V. Géli, M. Giraud-Panis, 2010, Molecular cell.

The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors

J. Pérez-Ortín, V. Pelechano, J. García-Martínez, 2010, Nucleic acids research.

Introns Protect Eukaryotic Genomes from Transcription-Associated Genetic Instability.

A. Grosso, V. Géli, G. Janbon, 2017, Molecular cell.

Structural Insights into Yeast Telomerase Recruitment to Telomeres

M. Lei, A. Bertuch, V. Géli, 2018, Cell.

Cotranslational assembly of the yeast SET1C histone methyltransferase complex

P. Kemmeren, F. Holstege, V. Géli, 2009, The EMBO journal.

RAP1 moonlights to activate NF-κB and Notch in ALT

V. Géli, D. Churikov, 2021, Science Signaling.

Telomerase Prevents Emphysema in Old Mice by Sustaining Subpopulations of Endothelial and AT2 Cells

E. Gilson, G. Giovinazzo, V. Géli, 2021, bioRxiv.

A high rate of telomeric sister chromatid exchange occurs in chronic lymphocytic leukaemia B‐cells

G. Salles, G. Berchem, V. Géli, 2016, British journal of haematology.

Histone stress: an unexplored source of chromosomal instability in cancer?

V. Géli, C. Desdouets, Douglas Maya Miles, 2019, Current Genetics.

SUMO-Dependent Relocalization of Eroded Telomeres to Nuclear Pore Complexes Controls Telomere Recombination.

V. Géli, M. Simon, M. Lisby, 2016, Cell reports.

TERRA Incognita at chromosome ends

V. Géli, S. Coulon, 2016, EMBO reports.

Sgs1 and Sae2 promote telomere replication by limiting accumulation of ssDNA

V. Géli, M. Simon, Vincent Géli, 2014, Nature Communications.

A two-step model for senescence triggered by a single critically short telomere

E. Gilson, V. Géli, K. Runge, 2009, Nature Cell Biology.

The DNA damage response at eroded telomeres and tethering to the nuclear pore complex

E. Gilson, V. Géli, M. Simon, 2009, Nature Cell Biology.

Nuclear envelope attachment of telomeres limits TERRA and telomeric rearrangements in quiescent fission yeast cells

Y. Gachet, C. Reyes, S. Tournier, 2020, Nucleic acids research.

Cdc13 and telomerase bind through different mechanisms at the lagging- and leading-strand telomeres.

V. Géli, S. Coulon, Julien Hardy, 2010, Molecular cell.

The MYST Domain Acetyltransferase Chameau Functions in Epigenetic Mechanisms of Transcriptional Repression

B. Miotto, Giacomo Cavalli, Y. Graba, 2002, Current Biology.

The AprX protein of Pseudomonas aeruginosa: a new substrate for the Apr type I secretion system.

A. Filloux, V. Géli, F. Duong, 2001, Gene.

Rad52 SUMOylation functions as a molecular switch that determines a balance between the Rad51- and Rad59-dependent survivors

V. Géli, M. Simon, M. Lisby, 2021, iScience.

Genome stability is guarded by yeast Rtt105 through multiple mechanisms.

V. Géli, Y. Corda, P. Luciano, 2021, Genetics.

Set1-dependent H3K4 methylation becomes critical for DNA replication fork progression in response to changes in S phase dynamics in Saccharomyces cerevisiae

V. Géli, C. de La Roche Saint-André, 2020, bioRxiv.

Replisome Function During Replicative Stress Is Modulated by Histone H3 Lysine 56 Acetylation Through Ctf4

S. Audebert, V. Géli, Y. Corda, 2015, Genetics.

Eroded telomeres are rearranged in quiescent fission yeast cells through duplications of subtelomeric sequences

V. Géli, B. Arcangioli, S. Coulon, 2017, Nature Communications.

Structural characterization of Set1 RNA recognition motifs and their role in histone H3 lysine 4 methylation.

Nicolas Leulliot, Herman van Tilbeurgh, Raphaël Guérois, 2006, Journal of molecular biology.

The fate of irreparable DNA double-strand breaks and eroded telomeres at the nuclear periphery

E. Gilson, V. Géli, M. Lisby, 2010, Nucleus.

Chapter 29 colicin transport, channel formation and inhibition

V. Géli, H. Bénédetti, 1996 .

Interactions of colicin A domains with phospholipid monolayers and liposomes: relevance to the mechanism of action.

R. Verger, F. Pattus, V. Géli, 1989, Biochemistry.

The membrane channel-forming colicin A: synthesis, secretion, structure, action and immunity.

V. Géli, C. Lazdunski, D. Baty, 1988, Biochimica et biophysica acta.

Histone H3 lysine 4 mono-methylation does not require ubiquitination of histone H2B.

Alain Verreault, Vicente Tordera, R. Lebrun, 2005, Journal of molecular biology.

An alpha-helical hydrophobic hairpin as a specific determinant in protein-protein interaction occurring in Escherichia coli colicin A and B immunity systems

V. Géli, C. Lazdunski, 1992, Journal of bacteriology.

Immunity Protein to Pore Forming Colicins

V. Géli, C. Lazdunski, 1992 .

Colicin A and B Immunity Systems

V. Géli, 2022 .

Ubiquitylation of the COMPASS component Swd2 links H2B ubiquitylation to H3K4 trimethylation

C. Dargemont, V. Géli, M. Hobeika, 2008, Nature Cell Biology.

Replication stress as a source of telomere recombination during replicative senescence in Saccharomyces cerevisiae.

V. Géli, M. Simon, D. Churikov, 2016, FEMS yeast research.

Posttranslational marks control architectural and functional plasticity of the nuclear pore complex basket

J. Salamero, C. Dargemont, V. Géli, 2016, The Journal of cell biology.

Rad59-Facilitated Acquisition of Y′ Elements by Short Telomeres Delays the Onset of Senescence

V. Géli, M. Simon, D. Churikov, 2014, PLoS genetics.

Recombinational DNA repair is regulated by compartmentalization of DNA lesions at the nuclear pore complex

V. Géli, M. Lisby, 2015, BioEssays : news and reviews in molecular, cellular and developmental biology.

The nuclear pore complex prevents sister chromatid recombination during replicative senescence

V. Géli, J. Whalen, M. Simon, 2020, Nature Communications.

Quantification of group A colicin import sites

V. Géli, D. Duché, D. Baty, 1995, Journal of bacteriology.

Functional cooperation of the mitochondrial processing peptidase subunits.

V. Géli, J. F. Hernández, A. Brandt, 1997, Journal of molecular biology.

The nuclear pore complex prevents sister chromatid recombination during replicative senescence

V. Géli, J. Whalen, M. Simon, 2020, Nature Communications.

STEEx, a boundary between the world of quiescence and the vegetative cycle

V. Géli, S. Coulon, Laetitia Maestroni, 2018, Current Genetics.

Transmembrane alpha-helix interactions are required for the functional assembly of the Escherichia coli Tol complex.

J. Popot, J. Lazzaroni, V. Géli, 1995, Journal of molecular biology.

Colicin A lysis protein promotes extracellular release of active human growth hormone accumulated in Escherichia coli cytoplasm.

V. Géli, C. Lazdunski, A. Bernadac, 1993, Biochimie.

Isolation and molecular and functional properties of the amino-terminal domain of colicin A.

V. Géli, C. Lazdunski, P. Sauve, 1989, European journal of biochemistry.

Synthesis and sequence-specific proteolysis of a hybrid protein (colicin A::growth hormone releasing factor) produced in Escherichia coli.

V. Géli, C. Lazdunski, D. Shire, 1989, Gene.

Topology and function of the integral membrane protein conferring immunity to colicin A

F. Pattus, V. Géli, C. Lazdunski, 1989, Molecular microbiology.

Use of a foreign epitope as a "tag" for the localization of minor proteins within a cell: the case of the immunity protein to colicin A.

V. Géli, C. Lazdunski, D. Baty, 1988, Proceedings of the National Academy of Sciences of the United States of America.

The colicin A pore‐forming domain fused to mitochondrial intermembrane space sorting signals can be functionally inserted into the Escherichia coli plasma membrane by a mechanism that bypasses the Tol proteins

V. Géli, K. Cunningham, H. Bénédetti, 1994, Molecular microbiology.

Study of the Import Mechanisms of Colicins Through Protein Engineering and K+ Efflux Kinetics

V. Géli, C. Lazdunski, D. Baty, 1992 .

NPCs and APBs: two HUBs of non-canonical homology-based recombination at telomeres?

V. Géli, M. Simon, Marion Dubarry, 2023, Cell cycle.

Chromatin assembly factor-1 preserves genome stability in ctf4Δ cells by promoting sister chromatid cohesion

V. Géli, Y. Corda, P. Luciano, 2023, Cell stress.

De novo telomere addition at chromosome breaks: Dangerous Liaisons

V. Géli, D. Churikov, 2017, The Journal of cell biology.

A molecular genetic approach to the functioning of the immunity protein to colicin A

F. Pattus, V. Géli, C. Lazdunski, 1986, Molecular and General Genetics MGG.

Stn1-Ten1 and Taz1 independently promote replication of subtelomeric fragile sequences in fission yeast.

A. Carr, V. Géli, S. Coulon, 2023, Cell reports.

Inherited human Apollo deficiency causes severe bone marrow failure and developmental defects.

P. Revy, I. Callebaut, V. Géli, 2022, Blood.

Sgs1 and Sae2 promote telomere replication by limiting accumulation of ssDNA

V. Géli, M. Simon, D. Churikov, 2014, Nature Communications.

The MAS-encoded processing protease of yeast mitochondria. Interaction of the purified enzyme with signal peptides and a purified precursor protein.

P. James, W. Oppliger, V. Géli, 1991, The Journal of biological chemistry.

Cdc13 and telomerase bind through different mechanisms at the lagging- and leading-strand telomeres.

V. Géli, Julien Hardy, V. Faure, 2010, Molecular cell.