J. Bjorge

发表

Delivery of gene targeting siRNAs to breast cancer cells using a multifunctional peptide complex that promotes both targeted delivery and endosomal release

J. Bjorge, A. Pang, D. Fujita, 2017, PloS one.

Selected glimpses into the activation and function of Src kinase

J. Bjorge, D. Fujita, A. Jakymiw, 2000, Oncogene.

A Novel Non-catalytic Mechanism Employed by the C-terminal Src-homologous Kinase to Inhibit Src-family Kinase Activity*

Heung-Chin Cheng, Hong-Jian Zhu, T. Mulhern, 2004, Journal of Biological Chemistry.

The von Hippel-Lindau Tumor Suppressor Protein Is Destabilized by Src: Implications for Tumor Angiogenesis and Progression.

J. Bjorge, D. Fujita, M. Chou, 2010, Genes & cancer.

Association of type I phosphatidylinositol kinase activity with mutationally activated forms of human pp60c-src

A. Tanaka, T. Chan, J. Bjorge, 1990, Molecular and cellular biology.

Epidermal growth factor receptor synthesis is stimulated by phorbol ester and epidermal growth factor. Evidence for a common mechanism.

J. E. Kudlow, J. Bjorge, J. Kudlow, 1987, The Journal of biological chemistry.

Phorbol ester or epidermal growth factor (EGF) stimulates the concurrent accumulation of mRNA for the EGF receptor and its ligand transforming growth factor-alpha in a breast cancer cell line.

A. Paterson, J. E. Kudlow, J. Bjorge, 1989, The Journal of biological chemistry.

Activation of human pp60 c-src

J. Bjorge, D. Fujita, J. Tracy, 1996 .

Activation of human pp60c-src.

J. Bjorge, D. Fujita, T. J. O'Connor, 1996, Biochemistry and cell biology = Biochimie et biologie cellulaire.

EGFR and HER2 levels are frequently elevated in colon cancer cells

Lihua Wu, J. Bjorge, D. Fujita, 2014 .

C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family tyrosine kinases.

A. Purcell, Heung-Chin Cheng, T. Smithgall, 2015, The Journal of Biological Chemistry.

Epidermal growth factor stimulates the synthesis of its own receptor in a human breast cancer cell line.

J. Bjorge, C. Y. Cheung, J. Kudlow, 1986, The Journal of biological chemistry.

Inhibition of stimulus‐dependent epidermal growth factor receptor and transforming growth factor‐α mRNA accumulation by the protein kinase C inhibitor staurosporine

A. Paterson, J. Bjorge, G. Mills, 1989, FEBS letters.

Regulation of EGF receptor and transforming growth factor-alpha expression.

A. Paterson, J. Bjorge, M. Kobrin, 1988, Advances in experimental medicine and biology.

A dual inhibitor of platelet-derived growth factor beta-receptor and Src kinase activity potently interferes with motogenic and mitogenic responses to PDGF in vascular smooth muscle cells. A novel candidate for prevention of vascular remodeling.

V Hombach, V. Hombach, A. Levitzki, 1999, Circulation research.

PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation.

J. Bjorge, D. Fujita, Shudong Zhu, 2007, Cancer research.

Decreased CHK protein levels are associated with Src activation in colon cancer cells

H. Cheng, J. Bjorge, D. Fujita, 2008, Oncogene.

Identification of Protein-tyrosine Phosphatase 1B as the Major Tyrosine Phosphatase Activity Capable of Dephosphorylating and Activating c-Src in Several Human Breast Cancer Cell Lines*

J. Bjorge, D. Fujita, Andy Pang, 2000, The Journal of Biological Chemistry.

Common and differential recognition of structural features in synthetic peptides by the catalytic domain and the Src-homology 2 (SH2) domain of pp60c-src.

H. Cheng, J. Bjorge, D. Fujita, 2009, The journal of peptide research : official journal of the American Peptide Society.

CSK-homologous kinase (CHK/MATK) is a potential colorectal cancer tumour suppressor gene epigenetically silenced by promoter methylation

O. Sieber, M. Foroutan, J. Mariadason, 2021, Oncogene.

Simultaneous siRNA Targeting of Src and Downstream Signaling Molecules Inhibit Tumor Formation and Metastasis of a Human Model Breast Cancer Cell Line

A. Magliocco, J. Bjorge, D. Fujita, 2011, PloS one.

Src Regulates the Activity of the ING1 Tumor Suppressor

K. Riabowol, J. Bjorge, D. Fujita, 2013, PloS one.

Characterization of Two Activated Mutants of Human pp60c-src That Escape c-Src Kinase Regulation by Distinct Mechanisms (*)

Heung-Chin Cheng, Jerry H. Wang, J. Bjorge, 1995, The Journal of Biological Chemistry.

Common in Vitro Substrate Specificity and Differential Src Homology 2 Domain Accessibility Displayed by Two Members of the Src Family of Protein-tyrosine Kinases, c-Src and Hck*

M. Hibbs, Heung-Chin Cheng, A. Dunn, 1998, The Journal of Biological Chemistry.

Modulation of annexin II tetramer by tyrosine phosphorylation.

D. Waisman, J. Bjorge, D. Fujita, 1995, Biochemistry.

Activated type I phosphatidylinositol kinase is associated with the epidermal growth factor (EGF) receptor following EGF stimulation.

H. Kung, T. Chan, M. Antczak, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Src is dephosphorylated at tyrosine 530 in human colon carcinomas

J. Bjorge, D. Fujita, Shudong Zhu, 2011, Chinese journal of cancer research = Chung-kuo yen cheng yen chiu.

Tyrosine Phosphorylation of Annexin II Tetramer Is Stimulated by Membrane Binding*

D. Waisman, J. Bjorge, D. Fujita, 1997, The Journal of Biological Chemistry.

C-terminal Src Kinase-homologous Kinase (CHK), a Unique Inhibitor Inactivating Multiple Active Conformations of Src Family Tyrosine Kinases*

A. Purcell, Heung-Chin Cheng, T. Smithgall, 2006, Journal of Biological Chemistry.

A Truncated Fragment of Src Protein Kinase Generated by Calpain-mediated Cleavage Is a Mediator of Neuronal Death in Excitotoxicity*

A. Hill, G. Dusting, Heung-Chin Cheng, 2013, The Journal of Biological Chemistry.

Mechanism of c-SRC activation in human melanocytes: elevated level of protein tyrosine phosphatase activity directed against the carboxy-terminal regulatory tyrosine.

J. H. Wang, H. Cheng, J. Bjorge, 1995, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

PI3K inhibition potentiates Bcl-2-dependent apoptosis in renal carcinoma cells

D. Cho, J. Mier, J. Bjorge, 2013, Journal of cellular and molecular medicine.

cSrc is a major cytosolic tyrosine kinase in vascular tissue.

M. Hollenberg, J. Bjorge, D. Fujita, 1999, Canadian journal of physiology and pharmacology.

TGF alpha in normal physiology.

J. Bjorge, J. Kudlow, 1990, Seminars in Cancer Biology.