A. Estepa

发表

Autophagy-inducing peptides from mammalian VSV and fish VHSV rhabdoviral G glycoproteins (G) as models for the development of new therapeutic molecules

J. Coll, P. Garcia-Valtanen, M. Ortega-Villaizán, 2014, Autophagy.

Use of Microarray Technology to Improve DNA Vaccines in Fish Aquaculture - The Rhabdoviral Model

Kenneth M. Coll, Brenda J. Freeman, E. Gomez-Casado, 2012 .

A comparative review on European-farmed finfish RNA viruses and their vaccines.

E. Gomez-Casado, J. Coll, A. Estepa, 2011, Vaccine.

Antibody recognition of the glycoprotein g of viral haemorrhagic septicemia virus (VHSV) purified in large amounts from insect larvae

E. Gomez-Casado, J. Escribano, A. Estepa, 2011, BMC Research Notes.

An ELISA for detection of trout antibodies to viral haemorrhagic septicemia virus using recombinant fragments of their viral G protein.

E. Gomez-Casado, J. Coll, A. Estepa, 2011, Journal of virological methods.

Identification of diverse defense mechanisms in trout red blood cells in response to VHSV halted viral replication.

J. Coll, M. Ortega-Villaizán, L. Perez, 2017, F1000Research.

Identification of diverse defense mechanisms in rainbow trout red blood cells in response to halted replication of VHS virus

J. Coll, M. Ortega-Villaizán, L. Perez, 2018, F1000Research.

Inhibition of SERPINe1 reduces rhabdoviral infections in zebrafish

J. Coll, A. Estepa, 2015, Fish & Shellfish Immunology.

Increasing Versatility of the DNA Vaccines through Modification of the Subcellular Location of Plasmid-Encoded Antigen Expression in the In Vivo Transfected Cells

J. Coll, P. Garcia-Valtanen, M. Ortega-Villaizán, 2013, PloS one.

Protection and antibody response induced by intramuscular DNA vaccine encoding for viral haemorrhagic septicaemia virus (VHSV) G glycoprotein in turbot (Scophthalmus maximus).

A. Falcó, J. Coll, A. Martínez-López, 2012, Fish & shellfish immunology.

Improving the safety of viral DNA vaccines: development of vectors containing both 5′ and 3′ homologous regulatory sequences from non-viral origin

E. Gomez-Casado, J. Coll, P. Garcia-Valtanen, 2013, Applied Microbiology and Biotechnology.

Replacement of the human cytomegalovirus promoter with fish enhancer and core elements to control the expression of the G gene of viral haemorrhagic septicemia virus (VHSV).

E. Gomez-Casado, J. Coll, A. Martínez-López, 2013, Journal of biotechnology.

Possible Applications to Aquaculture of Salmonid Sleeping Beauty Transposon Vectors

A. Estepa, P. Encinas, J. coll, 2011 .

Transfection improvements of fish cell lines by using deacylated polyethylenimine of selected molecular weights.

E. Chaves-Pozo, A. Cuesta, A. Falcó, 2009, Fish & shellfish immunology.

The immunogenicity of viral haemorragic septicaemia rhabdovirus (VHSV) DNA vaccines can depend on plasmid regulatory sequences.

A. Falcó, J. Coll, M. Ortega-Villaizán, 2009, Vaccine.

Identification of selective inhibitors of VHSV from biased combinatorial libraries of N,N'-disubstituted 2,5-piperazinediones.

A. Falcó, V. Más, J. Coll, 2006, Antiviral research.

Fish transposons and their potential use in aquaculture.

J. Coll, A. Estepa, C. Tafalla, 2006, Journal of biotechnology.

Antimicrobial peptides as model molecules for the development of novel antiviral agents in aquaculture.

A. Falcó, J. Coll, M. Ortega-Villaizán, 2009, Mini reviews in medicinal chemistry.

Protective effect of a recombinant VHSV-G vaccine using poly(I:C) loaded nanoparticles as an adjuvant in zebrafish (Danio rerio) infection model.

T. Gjøen, Gareth Griffiths, A. Estepa, 2016, Developmental and comparative immunology.

Zebra Fish Lacking Adaptive Immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene Expression of Apoptosis, Multigene Families, and Interferon-Related Genes

J. Coll, P. Garcia-Valtanen, M. Ortega-Villaizán, 2017, Front. Immunol..

Identification of Multipath Genes Differentially Expressed in Pathway-Targeted Microarrays in Zebrafish Infected and Surviving Spring Viremia Carp Virus (SVCV) Suggest Preventive Drug Candidates

E. Gomez-Casado, P. Garcia-Valtanen, A. Estepa, 2013, PloS one.

Mytilus galloprovincialis Myticin C: A Chemotactic Molecule with Antiviral Activity and Immunoregulatory Properties

A. Falcó, A. Figueras, A. Estepa, 2011, PloS one.

Ex vivo transfection of trout pronephros leukocytes, a model for cell culture screening of fish DNA vaccine candidates.

J. Coll, P. Garcia-Valtanen, M. Ortega-Villaizán, 2012, Vaccine.

TNFα Impairs Rhabdoviral Clearance by Inhibiting the Host Autophagic Antiviral Response

J. Meseguer, A. Falcó, A. Estepa, 2016, PLoS pathogens.

In vitro analysis of the factors contributing to the antiviral state induced by a plasmid encoding the viral haemorrhagic septicaemia virus glycoprotein G in transfected trout cells.

A. Falcó, J. Coll, M. Ortega-Villaizán, 2011, Vaccine.

The rainbow trout TLR9 gene and its role in the immune responses elicited by a plasmid encoding the glycoprotein G of the viral haemorrhagic septicaemia rhabdovirus (VHSV).

A. Falcó, J. Coll, M. Ortega-Villaizán, 2009, Molecular immunology.

Rapid detection and quantitation of viral hemorrhagic septicemia virus in experimentally challenged rainbow trout by real-time RT-PCR.

L. Perez, A. Estepa, V. Chico, 2006, Journal of virological methods.

In vivo modulation of the rainbow trout (Oncorhynchus mykiss) immune response by the human alpha defensin 1, HNP1.

A. Falcó, J. Coll, L. Perez, 2008, Fish & shellfish immunology.

Inhibitory effect of mycophenolic acid on the replication of infectious pancreatic necrosis virus and viral hemorrhagic septicemia virus.

L. Perez, A. Estepa, L. Marroqui, 2008, Antiviral research.

The introduction of multi-copy CpG motifs into an antiviral DNA vaccine strongly up-regulates its immunogenicity in fish.

A. Cuesta, A. Estepa, C. Tafalla, 2011, Vaccine.

pH-Dependent Solution Structure and Activity of a Reduced Form of the Host-Defense Peptide Myticin C (Myt C) from the Mussel Mytilus galloprovincialis

J. Encinar, P. Garcia-Valtanen, R. Medina-Gali, 2013, Marine drugs.

Stabilization of neutral polyfluorene in aqueous solution through their interaction with phospholipids and sol-gel encapsulation.

R. Mallavia, C. Mateo, A. Estepa, 2013, ACS applied materials & interfaces.

Antiviral Activity of Myticin C Peptide from Mussel: an Ancient Defense against Herpesviruses

A. Figueras, A. Estepa, B. Novoa, 2016, Journal of Virology.

VHSV G glycoprotein major determinants implicated in triggering the host type I IFN antiviral response as DNA vaccine molecular adjuvants.

E. Gomez-Casado, J. Coll, P. Garcia-Valtanen, 2014, Vaccine.

In vitro and in vivo differential expression of rainbow trout (Oncorhynchus mykiss) Mx isoforms in response to viral haemorrhagic septicaemia virus (VHSV) G gene, poly I:C and VHSV.

J. Coll, L. Perez, A. Estepa, 2007, Fish & shellfish immunology.

Enhancement of fish mortality by rhabdovirus infection after immunization with a viral nucleoprotein peptide.

J. Coll, A. Estepa, 1993, Viral immunology.

Targeting and stimulation of the zebrafish (Danio rerio) innate immune system with LPS/dsRNA-loaded nanoliposomes.

N. Roher, D. Maspoch, P. Garcia-Valtanen, 2014, Vaccine.

In vitro neutralization of viral hemorrhagic septicemia virus by plasma from immunized zebrafish.

E. Gomez-Casado, A. Falcó, A. Estepa, 2013, Zebrafish.

Rainbow trout surviving infections of viral haemorrhagic septicemia virus (VHSV) show lasting antibodies to recombinant G protein fragments.

E. Gomez-Casado, J. Coll, A. Estepa, 2011, Fish & shellfish immunology.

Differential effects of oleuropein, a biophenol from Olea europaea, on anionic and zwiterionic phospholipid model membranes.

A. Estepa, L. Perez-Fons, V. Micol, 2005, Chemistry and physics of lipids.

Structure and functionalities of the human c‐reactive protein compared to the zebrafish multigene family of c‐reactive‐like proteins

J. Encinar, A. Falcó, J. Coll, 2017, Developmental and comparative immunology.

The olive leaf extract exhibits antiviral activity against viral haemorrhagic septicaemia rhabdovirus (VHSV).

L. Perez, A. Estepa, L. Perez-Fons, 2005, Antiviral research.

The Relationship between Oleuropein Antimicrobial Activity and its Effects on Biological Membranes

A. Estepa, V. Micol, N. Caturla, 2010 .

Expression and antiviral activity of a beta-defensin-like peptide identified in the rainbow trout (Oncorhynchus mykiss) EST sequences.

A. Falcó, J. Coll, L. Perez, 2008, Molecular immunology.

Dual antiviral activity of human alpha-defensin-1 against viral haemorrhagic septicaemia rhabdovirus (VHSV): inactivation of virus particles and induction of a type I interferon-related response.

A. Falcó, J. Coll, L. Perez, 2007, Antiviral research.

Salmonid viral haemorrhagic septicaemia virus: fusion-related enhancement of virus infectivity by peptides derived from viral glycoprotein G or a combinatorial library.

J. Encinar, E. Pérez-Payá, A. Ferrer-Montiel, 2002, The Journal of general virology.

Enhanced detection of viral hemorrhagic septicemia virus (a salmonid rhabdovirus) by pretreatment of the virus with a combinatorial library-selected peptide.

J. Coll, L. Perez, A. Estepa, 2002, Journal of virological methods.

A Protein G Fragment from the Salmonid Viral Hemorrhagic Septicemia Rhabdovirus Induces Cell-to-Cell Fusion and Membrane Phosphatidylserine Translocation at Low pH*

J. Encinar, J. Coll, L. Perez, 2001, The Journal of Biological Chemistry.

Mapping of linear antibody epitopes of the glycoprotein of VHSV, a salmonid rhabdovirus.

J. Coll, L. Perez, A. Estepa, 1998, Diseases of aquatic organisms.

Temperature and pH requirements for viral haemorrhagic septicemia virus induced cell fusion

A. Estepa, J. coll, 1997 .

Fast neutralization/immunoperoxidase assay for viral haemorrhagic septicaemia with anti-nucleoprotein monoclonal antibody.

J. Coll, A. Estepa, G. Lorenzo, 1996, Journal of virological methods.

Pepscan mapping and fusion-related properties of the major phosphatidylserine-binding domain of the glycoprotein of viral hemorrhagic septicemia virus, a salmonid rhabdovirus.

J. Coll, A. Estepa, J. coll, 1996, Virology.

Mapping of the G and N regions of viral haemorrhagic septicaemia virus (VHSV) inducing lymphoproliferation by pepscan.

J. Coll, A. Estepa, S. Chilmonczyk, 1995, Veterinary research.

In addition to its antiviral and immunomodulatory properties, the zebrafish β-defensin 2 (zfBD2) is a potent viral DNA vaccine molecular adjuvant.

J. Coll, P. Garcia-Valtanen, M. Ortega-Villaizán, 2014, Antiviral research.

A. Estepa, L. Perez-Fons, V. Micol, 2004, Biochemical pharmacology.

Melittin-loaded immunoliposomes against viral surface proteins, a new approach to antiviral therapy.

A. Falcó, A. Estepa, J. coll, 2013, Antiviral research.

Characterization of an infectious pancreatic necrosis (IPN) virus carrier cell culture with resistance to superinfection with heterologous viruses.

A. Falcó, L. Perez, A. Estepa, 2011, Veterinary microbiology.

New tools to study RNA interference to fish viruses: Fish cell lines permanently expressing siRNAs targeting the viral polymerase of viral hemorrhagic septicemia virus.

S. Ruiz, J. Coll, A. Estepa, 2009, Antiviral research.

Properties of blast colonies obtained from trout head-kidney in fibrin clot cultures

J. Coll, A. Estepa, 1993 .

Assessment of the inhibitory effect of ribavirin on the rainbow trout rhabdovirus VHSV by real-time reverse-transcription PCR.

L. Perez, A. Estepa, L. Marroqui, 2007, Veterinary microbiology.

Rag1 immunodeficiency‐induced early aging and senescence in zebrafish are dependent on chronic inflammation and oxidative stress

M. Cayuela, M. Collado, J. Coll, 2019, Aging cell.

Nodavirus Infection of Sea Bass (Dicentrarchus labrax) Induces Up-Regulation of Galectin-1 Expression with Potential Anti-Inflammatory Activity12

H. Ahmed, G. Vasta, A. Figueras, 2009, The Journal of Immunology.

Transfection of epithelioma papulosum cyprini (EPC) carp cells

A. Rocha, J. Coll, A. Estepa, 2001, Biotechnology Letters.

The potential for antimicrobial peptides to improve fish health in aquaculture

A. Falcó, A. Estepa, J. coll, 2012 .

In vitro search for alternative promoters to the human immediate early cytomegalovirus (IE-cMV) to express the G gene of viral haemorrhagic septicemia virus (VHSV) in fish epithelial cells.

A. Cuesta, S. Ruiz, J. Coll, 2008, Vaccine.

Stable expression of bioactive recombinant pleurocidin in a fish cell line

A. Falcó, A. Rocha, J. Coll, 2006, Applied Microbiology and Biotechnology.

Transcriptome Profiles Associated to VHSV Infection or DNA Vaccination in Turbot (Scophthalmus maximus)

S. Mackenzie, A. Figueras, A. Estepa, 2014, PloS one.

Regulation of rainbow trout (Oncorhynchus mykiss) interleukin-8 receptor (IL-8R) gene transcription in response to viral hemorrhagic septicemia virus (VHSV), DNA vaccination and chemokines.

A. Estepa, J. coll, J. Montero, 2008, Fish & shellfish immunology.

In vitro susceptibility of rainbow trout fin cells to viral haemorrhagic septicaemia virus

J. Coll, A. Estepa, D. Frías, 1993 .

Susceptibility of trout kidney macrophages to viral hemorrhagic septicemia virus.

J. Coll, A. Estepa, D. Frías, 1992, Viral immunology.

Infection of mitogen‐stimulated trout leucocytes with salmonid viruses

J. Coll, A. Estepa, 1991 .

Stimulation of adherent cells by addition of purified proteins of viral hemorrhagic septicemia virus to trout kidney cell cultures.

J. Coll, A. Estepa, F. Sanz, 1991, Viral immunology.

Viral immune defences in fish.

J. Coll, A. Estepa, C. Tafalla, 2009 .

Viral-antigen dependence and T-cell receptor expression in leucocytes from rhabdovirus immunized trout.

J. Coll, A. Estepa, A. Ezquerra, 1999, Veterinary immunology and immunopathology.

The in vitro infection of the hematopoietic stroma of trout kidney by hemorrhagic septicemia rhabdovirus.

J. Coll, A. Estepa, A. Villena, 1993, Viral immunology.

Recombinant protein fragments from haemorrhagic septicaemia rhabdovirus stimulate trout leukocyte anamnestic responses in vitro.

J. Coll, A. Estepa, M. Thiry, 1994, The Journal of general virology.

Mitogen-induced proliferation of trout kidney leucocytes by one-step culture in fibrin clots.

J. Coll, A. Estepa, 1992, Veterinary immunology and immunopathology.

In vitro immunostimulants for optimal responses of kidney cells from healthy trout and from trout surviving viral haemorrhagic septicaemia virus disease

J. Coll, A. Estepa, 1992 .

Reversible Inhibition of Spreading of In Vitro Infection and Imbalance of Viral Protein Accumulation at Low pH in Viral Hemorrhagic Septicemia Rhabdovirus, a Salmonid Rhabdovirus

A. Rocha, J. Coll, L. Perez, 2004, Journal of Virology.

An in vitro method to obtain T-lymphocyte-like cells from the trout.

J. Coll, A. Estepa, 1997, Journal of immunological methods.

Development of new therapeutical/adjuvant molecules by pepscan mapping of autophagy and IFN inducing determinants of rhabdoviral G proteins.

J. Coll, P. Garcia-Valtanen, M. Ortega-Villaizán, 2016, Molecular immunology.

Innate Multigene Family Memories Are Implicated in the Viral-Survivor Zebrafish Phenotype

A. Estepa, J. coll, 2015, PloS one.

A sandwich ELISA to detect VHSV and IPNV in turbot

A. Estepa, J. C. Morales, M. Brañas, 1994, Aquaculture International.

Antibody response to a fragment of the protein G of VHS rhabdovirus in immunised trout.

A. Rocha, J. Coll, L. Perez, 2002, Veterinary immunology and immunopathology.

A model to study fish DNA immersion vaccination by using the green fluorescent protein

R. Blasco, J. Coll, A. Estepa, 1999 .

Phospholipid interactions of a peptide from the fusion-related domain of the glycoprotein of VHSV, a fish rhabdovirus.

J. González-Ros, J. Coll, A. Estepa, 1998, Virology.

Phosphatidylserine binding to solid-phase rhabdoviral peptides: a new method to study phospholipid/viral protein interactions.

J. Coll, A. Estepa, 1996, Journal of virological methods.

Transcriptome analysis of rainbow trout in response to non-virion (NV) protein of viral haemorrhagic septicaemia virus (VHSV)

E. Gomez-Casado, J. Coll, A. Estepa, 2015, Applied Microbiology and Biotechnology.

Structure, binding and neutralization of VHSV with synthetic peptides.

J. Coll, A. Estepa, M. Fernández-Alonso, 1999, Virus research.

Application of Inducible and Targeted Gene Strategies to Produce Transgenic Fish: A Review

A. Rocha, S. Ruiz, J. Coll, 2004, Marine Biotechnology.

Effects of recombinant flagellin B and its ND1 domain from Vibrio anguillarum on macrophages from gilthead seabream (Sparus aurata L.) and rainbow trout (Oncorhynchus mykiss, W.).

A. Estepa, L. Mercado, V. Mulero, 2015, Fish & shellfish immunology.

Induction of viral interference by IPNV-carrier cells on target cells: A cell co-culture study.

L. Perez, A. Estepa, Susana Torres,, 2016, Fish & shellfish immunology.

Zebrafish fin immune responses during high mortality infections with viral haemorrhagic septicemia rhabdovirus. A proteomic and transcriptomic approach

A. Figueras, A. Estepa, P. Encinas, 2010, BMC Genomics.

Optimization of fixed-permeabilized cell monolayers for high throughput micro-neutralizing antibody assays: application to the zebrafish/viral hemorrhagic septicemia virus (vhsv) model.

E. Gomez-Casado, J. Coll, A. Estepa, 2013, Journal of virological methods.

Improving the safety of viral DNA vaccines: development of vectors containing both 5′ and 3′ homologous regulatory sequences from non-viral origin

E. Gomez-Casado, J. Coll, P. Garcia-Valtanen, 2013, Applied Microbiology and Biotechnology.

Nucleated Teleost Erythrocytes Play an Nk-Lysin- and Autophagy-Dependent Role in Antiviral Immunity

A. Figueras, A. Estepa, B. Novoa, 2017, Front. Immunol..

Review. Fish as biofactories: indicible genetic systems and gene targeting

A. Rocha, S. Ruiz, J. Coll, 2003 .

Transgenic animals as biofactories

A. Rocha, S. Ruiz, J. Coll, 2003 .

Behavioural fever is a synergic signal amplifying the innate immune response

N. Roher, P. Garcia-Valtanen, S. Mackenzie, 2013, Proceedings of the Royal Society B: Biological Sciences.

Infection of Sea Bass ( Dicentrarchus labrax ) Induces Upregulation of Galectin-1 Expression in Head Kidney , with Potential Anti-Inflammatory Activity

H. Ahmed, G. Vasta, A. Figueras, 2009 .

Different peptides from hemorrhagic septicemia rhabdoviral proteins stimulate leucocyte proliferation with individual fish variation.

J. Coll, A. Estepa, S. Chilmonczyk, 1995, Virology.

Transcriptome analysis of rainbow trout in response to non-virion (NV) protein of viral haemorrhagic septicaemia virus (VHSV)

E. Gomez-Casado, J. Coll, A. Estepa, 2015, Applied Microbiology and Biotechnology.

Pepscan Mapping of Viral Hemorrhagic Septicemia Virus Glycoprotein G Major Lineal Determinants Implicated in Triggering Host Cell Antiviral Responses Mediated by Type I Interferon

A. Falcó, J. Coll, M. Ortega-Villaizán, 2010, Journal of Virology.

Detection of trout haemorrhagic septicaemia rhabdovirus by capture with monoclonal antibodies and amplification with PCR.

J. Coll, A. Estepa, F. Ponz, 1995, Veterinary Research.

Antiviral activity produced by an IPNV-carrier EPC cell culture confers resistance to VHSV infection.

P. Garcia-Valtanen, L. Perez, A. Estepa, 2013, Veterinary microbiology.

Corrigendum to “A comparative review on European-farmed finfish RNA viruses and their vaccines” by Gomez-Casado et al. [Vaccine 29 (15) (2011) 2657–2671]

E. Gomez-Casado, J. Coll, A. Estepa, 2011 .

Identification of diverse defense mechanisms in rainbow trout red blood cells in response to halted replication of VHS virus

J. Coll, M. Ortega-Villaizán, L. Perez, 2017, F1000Research.

Optimization of fixed-permeabilized cell monolayers for high throughput micro-neutralizing antibody assays: application to the zebrafish/viral hemorrhagic septicemia virus (vhsv) model.

E. Gomez-Casado, J. Coll, A. Estepa, 2013, Journal of virological methods.