B. Wehrle-Haller

D. Boettiger, B. Wehrle-Haller, S. Tabone-Eglinger, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Paxillin: A Hub for Mechano-Transduction from the β3 Integrin-Talin-Kindlin Axis

Marta Ripamonti, B. Wehrle-Haller, I. de Curtis, 2022, Frontiers in Cell and Developmental Biology.

Epithelial synthesis of tenascin at tips of growing bronchi and graded accumulation in basement membrane and mesenchyme.

J. Spring, M. Chiquet, B. Wehrle-Haller, 1991, Experimental cell research.

Chick laminin: isolation by monoclonal antibodies and differential distribution of variants in the embryo.

M. Chiquet, B. Wehrle-Haller, D. Brubacher, 1991, Experimental cell research.

-Smooth Muscle Actin Is Crucial for Focal Adhesion Maturation in Myofibroblasts□V

B. Hinz, V. Dugina, C. Chaponnier, 2003 .

Marching at the front and dragging behind: differential V 3-integrin turnover regulates focal adhesion behavior

B. Hinz, B. Imhof, B. Wehrle-Haller, 2001 .

β1 integrin–dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin

D. Lallemand, D. Bouvard, B. Wehrle-Haller, 2017, The Journal of Biological Chemistry.

Receptor tyrosine kinase-dependent neural crest migration in response to differentially localized growth factors.

B. Wehrle-Haller, J. A. Weston, 1997, BioEssays : news and reviews in molecular, cellular and developmental biology.

The mechano-sensitive response of β1 integrin promotes SRC-positive late endosome recycling and activation of Yes-associated protein

D. Lallemand, P. Rondé, D. Bouvard, 2020, The Journal of Biological Chemistry.

Integrin-dependent YAP signaling requires LAMTOR1 mediated delivery of Src to the plasma membrane

D. Lallemand, P. Rondé, D. Bouvard, 2019, bioRxiv.

Severe congenital hyperinsulinism caused by a mutation in the Kir6.2 subunit of the adenosine triphosphate-sensitive potassium channel impairing trafficking and function.

B. Wehrle-Haller, A. Bloc, V. Schwitzgebel, 2005, The Journal of clinical endocrinology and metabolism.

New PI(4,5)P2- and membrane proximal integrin–binding motifs in the talin head control β3-integrin clustering

Wei Liu, Viola Vogel, Vesa P. Hytönen, 2009, The Journal of cell biology.

Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding

V. Hytönen, J. Määttä, R. Cheng, 2020, Proceedings of the National Academy of Sciences of the United States of America.

CD44 and beta3 integrin organize two functionally distinct actin-based domains in osteoclasts.

E. Génot, F. Saltel, B. Wehrle-Haller, 2007, Molecular biology of the cell.

Adaptation of cell spreading to varying fibronectin densities and topographies is facilitated by β1 integrins

M. Bastmeyer, M. Hippler, B. Wehrle-Haller, 2022, Frontiers in Bioengineering and Biotechnology.

Structural and functional analysis of LIM domain-dependent recruitment of paxillin to focal adhesions

Nicolas Liaudet, Marta Ripamonti, B. Wehrle-Haller, 2020 .

Core Matrisome Protein Signature During Periodontal Ligament Maturation From Pre-occlusal Eruption to Occlusal Function

B. Wehrle-Haller, S. Kiliaridis, Aouatef Ait-Lounis, 2020, Frontiers in Physiology.

The green revolution

B. Wehrle-Haller, 2000 .

Mechanical stability of talin rod controls cell migration and substrate sensing

T. Ihalainen, M. Bastmeyer, V. Hytönen, 2017, Scientific Reports.

Tenascin (cytotactin): an extracellular matrix protein involved in morphogenesis of the nervous system

M. Chiquet, B. Wehrle-Haller, M. Koch, 1991 .

The Role of Integrins in Cell Migration

B. Wehrle-Haller, 2013 .

The mechanisms and dynamics of (cid:1) v (cid:2) 3 integrin clustering in living cells

F. Saltel, C. Cluzel, B. Imhof, 2005 .

A Highly Speci fi c Gold Nanoprobe for Live-Cell Single-Molecule Imaging

A. Gautreau, Cécile Leduc, G. Giannone, 2013 .

Stem Cell Factor Presentation to c-Kit

B. Imhof, B. Wehrle-Haller, 2001, The Journal of Biological Chemistry.

Novel Mechanistic Link between Focal Adhesion Remodeling and Glucose-stimulated Insulin Secretion*

P. Halban, B. Wehrle-Haller, Alejandra Tomas, 2011, The Journal of Biological Chemistry.

Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis.

S. Theander, F. Saltel, C. Wollheim, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Molecular identification of distinct neurogenic and melanogenic neural crest sublineages

B. Wehrle-Haller, Juan Gao, P. D. Henion, 2003, Development.

Membrane‐bound Kit ligand regulates melanocyte adhesion and survival, providing physical interaction with an intraepithelial niche

B. Wehrle-Haller, S. Tabone-Eglinger, N. Aebischer, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A Specific Endoplasmic Reticulum Export Signal Drives Transport of Stem Cell Factor (Kitl) to the Cell Surface*

B. Imhof, B. Wehrle-Haller, F. Paulhe, 2004, Journal of Biological Chemistry.

Kindlin-2 Mediates Mechanical Activation of Cardiac Myofibroblasts

B. Hinz, S. Clément, B. Wehrle-Haller, 2020, Cells.

Cytoplasmic methylation fuels leukocyte invasion

B. Wehrle-Haller, 2015, Nature Immunology.

Peripheral blood CD56bright NK cells respond to stem cell factor and adhere to its membrane‐bound form after upregulation of c‐kit

A. Pradier, B. Wehrle-Haller, E. Roosnek, 2014, European journal of immunology.

Induced Pluripotent Stem Cells to Understand Mucopolysaccharidosis. I: Demonstration of a Migration Defect in Neural Precursors

M. Baumgartner, K. Krause, B. Wehrle-Haller, 2020, Cells.

Cell Adhesion by Integrins.

M. Bachmann, V. Hytönen, B. Wehrle-Haller, 2019, Physiological reviews.

Role and impact of the extracellular matrix on integrin‐mediated pancreatic β‐cell functions

B. Wehrle-Haller, C. Arous, 2017, Biology of the cell.

Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precursor dispersal and survival on the lateral neural crest migration pathway.

B. Wehrle-Haller, J. A. Weston, 1995, Development.

Ectopic c-kit expression affects the fate of melanocyte precursors in Patch mutant embryos.

B. Wehrle-Haller, J. A. Weston, K. Morrison-Graham, 1996, Developmental biology.

Altered cell-surface targeting of stem cell factor causes loss of melanocyte precursors in Steel17H mutant mice.

B. Wehrle-Haller, J. A. Weston, 1999, Developmental biology.

The role of Kit-ligand in melanocyte development and epidermal homeostasis.

B. Wehrle-Haller, 2003, Pigment cell research.

Actin-dependent lamellipodia formation and microtubule-dependent tail retraction control-directed cell migration.

B. Hinz, B. Imhof, B. Wehrle-Haller, 2000, Molecular biology of the cell.

PECAM-1/CD31 trans-homophilic binding at the intercellular junctions is independent of its cytoplasmic domain; evidence for heterophilic interaction with integrin alphavbeta3 in Cis.

B. Engelhardt, B. Imhof, B. Wehrle-Haller, 2000, Molecular biology of the cell.

Mechanosensing in cell-matrix adhesions - Converting tension into chemical signals.

V. Hytönen, B. Wehrle-Haller, 2016, Experimental cell research.

Integrins: versatile receptors controlling melanocyte adhesion, migration and proliferation

B. Wehrle-Haller, Perrine Pinon, 2011, Pigment cell & melanoma research.

Plasticity of the actin cytoskeleton in response to extracellular matrix nanostructure and dimensionality.

P. Friedl, B. Wehrle-Haller, Josefine Starke, 2014, Biochemical Society transactions.

Analysis of melanocyte precursors in Nf1 mutants reveals that MGF/KIT signaling promotes directed cell migration independent of its function in cell survival.

B. Wehrle-Haller, J. A. Weston, M. Meller, 2001, Developmental biology.

Integrin and autocrine IGF2 pathways control fasting insulin secretion in β-cells

M. Mizgier, B. Wehrle-Haller, M. Pinget, 2020, The Journal of Biological Chemistry.

Talin-bound NPLY motif recruits integrin-signaling adapters to regulate cell spreading and mechanosensing

M. Bachmann, M. Bastmeyer, V. Hytönen, 2014, The Journal of cell biology.

Protein conformation as a regulator of cell-matrix adhesion.

V. Hytönen, B. Wehrle-Haller, 2014, Physical chemistry chemical physics : PCCP.

Multiscale Modeling of Form and Function

Adam J Engler, V. Weaver, A. Engler, 2009, Science.

Cell-matrix adhesion complexes: master control machinery of cell migration.

Staffan Strömblad, John G Lock, S. Strömblad, 2008, Seminars in cancer biology.

Alpha-smooth muscle actin is crucial for focal adhesion maturation in myofibroblasts.

B. Hinz, V. Dugina, C. Chaponnier, 2003, Molecular biology of the cell.

An adhesion molecule in free‐living Dictyostelium amoebae with integrin β features

S. Charette, P. Nair, P. Cosson, 2006, EMBO reports.

Dimerization of Kit‐ligand and efficient cell‐surface presentation requires a conserved Ser‐Gly‐Gly‐Tyr motif in its transmembrane domain

B. Imhof, B. Wehrle-Haller, F. Paulhe, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Integrin and glycocalyx mediated contributions to cell adhesion identified by single cell force spectroscopy

D. Boettiger, B. Wehrle-Haller, David Boettiger, 2010, Journal of physics. Condensed matter : an Institute of Physics journal.

Force-dependent ligand sensing enables αVβ3 integrin to differentiate between fibronectin and high-affinity ligands

M. Bachmann, M. Bastmeyer, V. Hytönen, 2017 .

The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering

M. Varjosalo, D. Svergun, I. Vattulainen, 2020, Journal of Cell Science.

Analysis of integrin dynamics by fluorescence recovery after photobleaching.

B. Wehrle-Haller, 2007, Methods in molecular biology.

The inner lives of focal adhesions.

Beat Imhof, B. Imhof, B. Wehrle-Haller, 2002, Trends in cell biology.

Integrin‐dependent pathologies

B. Imhof, B. Wehrle-Haller, Bernhard Wehrle-Haller, 2003, The Journal of pathology.

β1D integrin splice variant stabilizes integrin dynamics and reduces integrin signaling by limiting paxillin recruitment

D. Boettiger, M. Bachmann, M. Bastmeyer, 2019, Journal of Cell Science.

Actin, microtubules and focal adhesion dynamics during cell migration.

B. Imhof, B. Wehrle-Haller, 2003, The international journal of biochemistry & cell biology.

Vav3 Mediates Pseudomonas aeruginosa Adhesion to the Cystic Fibrosis Airway Epithelium.

A. Zoso, M. Bacchetta, M. Chanson, 2020, Cell reports.

Astrocytes spatially restrict VEGF signaling by polarized secretion and incorporation of VEGF into the actively assembling extracellular matrix

J. Kiss, T. Balla, B. Wehrle-Haller, 2016, Glia.

Phosphorylated paxillin and phosphorylated FAK constitute subregions within focal adhesions.

M. Bachmann, M. Bastmeyer, B. Wehrle-Haller, 2022, Journal of cell science.

New tools to study the interaction between integrins and latent TGFβ1

M. Bachmann, B. Wehrle-Haller, Jérémy Kessler, 2023, bioRxiv.

The AW519 antibody specifically detects αvβ6 integrin by flow cytometry

M. Bachmann, B. Wehrle-Haller, Jérémy Kessler, 2022, Antibody Reports.

Induction of ligand promiscuity of αVβ3 integrin by mechanical force

M. Bachmann, M. Bastmeyer, V. Hytönen, 2020, Journal of Cell Science.

Intracellular interleukin-1 receptor antagonist type 1 antagonizes the stimulatory effect of interleukin-1 alpha precursor on cell motility.

C. Gabay, B. Wehrle-Haller, F. Merhi‐Soussi, 2005, Cytokine.

TiNxOy coatings facilitate the initial adhesion of osteoblasts to create a suitable environment for their proliferation and the recruitment of endothelial cells

S. Durual, B. Wehrle-Haller, O. Banakh, 2017, Biomedical materials.

Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy.

P. Carmeliet, S. Goff, D. Collen, 2005, The Journal of clinical investigation.

Diminished matrix metalloproteinase 2 (MMP-2) in ectomesenchyme-derived tissues of the Patch mutant mouse: regulation of MMP-2 by PDGF and effects on mesenchymal cell migration.

B. Wehrle-Haller, P. McGuire, J. Robbins, 1999, Developmental biology.

Stimulation of Fibronectin Matrix Assembly by Lysine Acetylation

J. Schwarzbauer, B. Wehrle-Haller, Birgit Kastberger, 2020, Cells.

ConFERMing the role of talin in integrin activation and mechanosignaling

M. Bachmann, V. Hytönen, B. Wehrle-Haller, 2023, Journal of cell science.

Intracellular signaling and perception of neuronal scaffold through integrins and their adapter proteins.

M. Bastmeyer, B. Wehrle-Haller, 2014, Progress in brain research.

Urokinase Receptor (CD87) Clustering in Detergent-Insoluble Adhesion Patches Leads to Cell Adhesion Independently of Integrins

K. Preissner, F. Saltel, S. Kanse, 2007, Cell communication & adhesion.

Ligand binding promiscuity of αVβ3 integrin is enlarged in response to mechanical force

M. Bachmann, M. Bastmeyer, V. Hytönen, 2018, bioRxiv.

Mechanotransduction of mesenchymal melanoma cell invasion into 3D collagen lattices: filopod-mediated extension-relaxation cycles and force anisotropy.

Peter Friedl, P. Friedl, K. Maaser, 2013, Experimental cell research.

The metabolic control of tissue integrity and function in health and disease

J. Schwarzbauer, B. Wehrle-Haller, 2015 .

Maturation of Filopodia Shaft Adhesions Is Upregulated by Local Cycles of Lamellipodia Advancements and Retractions

V. Vogel, B. Wehrle-Haller, Wei Hu, 2014, PloS one.

Influenza A virus exploits transferrin receptor recycling to enter host cells

V. Serre-Beinier, V. Zoete, M. Schmolke, 2023, Proceedings of the National Academy of Sciences of the United States of America.

Phosphorylated paxillin and FAK constitute subregions within focal adhesions

M. Bachmann, M. Bastmeyer, B. Wehrle-Haller, 2020 .

Simultaneous Study of the Recruitment of Monocyte Subpopulations Under Flow In Vitro.

B. Imhof, B. Wehrle-Haller, A. Sidibé, 2018, Journal of visualized experiments : JoVE.

A highly specific gold nanoprobe for live-cell single-molecule imaging.

A. Gautreau, Cécile Leduc, G. Giannone, 2013, Nano letters.