J. McKinzie

发表

Structure-activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part 1.

M. Siegel, P. Emmerson, P. Surface, 2007, Bioorganic & medicinal chemistry letters.

Na+ modulation, inverse agonism, and anorectic potency of 4-phenylpiperidine opioid antagonists.

P. Emmerson, P. Surface, J. McKinzie, 2004, European journal of pharmacology.

Determining Pharmacological Selectivity of the Kappa Opioid Receptor Antagonist LY2456302 Using Pupillometry as a Translational Biomarker in Rat and Human

J. Suico, D. McKinzie, J. McKinzie, 2015, The international journal of neuropsychopharmacology.

κ‐Opioid receptors control the metabolic response to a high‐energy diet in mice

J. Lockwood, M. Tschöp, J. Pintar, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Determination of [35S]guanosine-5'-O-(3-thio)triphosphate binding mediated by cholinergic muscarinic receptors in membranes from Chinese hamster ovary cells and rat striatum using an anti-G protein scintillation proximity assay.

D. McClure, J. McKinzie, C. Felder, 1999, The Journal of pharmacology and experimental therapeutics.

LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders

D. McKinzie, Xia Li, J. Witkin, 2014, Neuropharmacology.

In vivo rat brain opioid receptor binding of LY255582 assessed with a novel method using LC/MS/MS and the administration of three tracers simultaneously.

J. McKinzie, M. Statnick, C. Mitch, 2007, Life sciences.

SAR and biological evaluation of novel trans-3,4-dimethyl-4-arylpiperidine derivatives as opioid antagonists.

M. Siegel, P. Emmerson, P. Surface, 2005, Bioorganic & medicinal chemistry letters.

Ontogenetic differences in ethanol-induced impairment of context and CS learning

N. Spear, D. McKinzie, Jieun Lee, 1996, Psychobiology.

Development of rapid tolerance to ethanol-stimulated serotonin release in the ventral hippocampus.

W. Mcbride, J. McKinzie, D. Bare, 1998, Alcoholism, clinical and experimental research.

Development of Displacement Binding and GTPγS Scintillation Proximity Assays for the Identification of Antagonists of the μ-Opioid Receptor

P. Emmerson, J. McKinzie, T. Suter, 2003 .

LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders

D. McKinzie, Xia Li, J. Witkin, 2014, Neuropharmacology.

Induction of the apoptosis-promoting protein Bak by perillyl alcohol in pancreatic ductal adenocarcinoma relative to untransformed ductal epithelial cells.

J. McKinzie, Y. D. Burke, P. Crowell, 1997, Carcinogenesis.

Structure activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part 2.

M. Siegel, P. Emmerson, P. Surface, 2007, Bioorganic & medicinal chemistry letters.