Qiu-feng Liu

发表

Free energy landscape for the binding process of Huperzine A to acetylcholinesterase

Jing Chen, Jianpeng Ma, Hualiang Jiang, 2013, Proceedings of the National Academy of Sciences.

Novel fatty acid binding protein 4 (FABP4) inhibitors: virtual screening, synthesis and crystal structure determination.

Weiliang Zhu, Kaixian Chen, Yechun Xu, 2015, European journal of medicinal chemistry.

From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4.

Weiliang Zhu, Qiu-feng Liu, H. Su, 2018, European journal of medicinal chemistry.

Discovery, optimization and biological evaluation for novel c-Met kinase inhibitors.

Yechun Xu, T. Lu, Yadong Chen, 2018, European journal of medicinal chemistry.

Discovery of 10H-Benzo[b]pyrido[2,3-e][1,4]oxazine AXL Inhibitors via Structure-Based Drug Design Targeting c-Met Kinase.

Qiu-feng Liu, H. Su, Yin-chun Ji, 2022, Journal of medicinal chemistry.

The Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as Novel Covalent Fibroblast Growth Factor Receptor (FGFR) Inhibitors by Rational Drug Design.

Hualiang Jiang, Yechun Xu, Hong Liu, 2019, Journal of medicinal chemistry.

Multisubstituted quinoxalines and pyrido[2,3-d]pyrimidines: synthesis and SAR study as tyrosine kinase c-Met inhibitors.

Yechun Xu, M. Geng, Qiu-feng Liu, 2012, Bioorganic & medicinal chemistry letters.

Discovery of 6-(difluoro(6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl)methyl)quinoline as a highly potent and selective c-Met inhibitor.

Yechun Xu, M. Geng, Qiu-feng Liu, 2016, European journal of medicinal chemistry.

Discovery of Anilinopyrimidines as Dual Inhibitors of c-Met and VEGFR-2: Synthesis, SAR, and Cellular Activity.

Yechun Xu, M. Geng, Qiu-feng Liu, 2014, ACS medicinal chemistry letters.

Structures of full-length glycoprotein hormone receptor signalling complexes

Hualiang Jiang, Shuyang Zhang, Xi Cheng, 2021, Nature.

Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors

Hualiang Jiang, Xi Cheng, Xinheng He, 2022, Nature Communications.

Design, synthesis, and biological evaluation of a series of benzo[de][1,7]naphthyridin-7(8H)-ones bearing a functionalized longer chain appendage as novel PARP1 inhibitors.

Qiufeng Liu, Shan-Shan Song, Yechun Xu, 2013, Journal of medicinal chemistry.

Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors.

Xuxing Chen, Qian He, Qiufeng Liu, 2018, European journal of medicinal chemistry.

Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor

Qiang Zhao, Xinheng He, H. Xu, 2021, Nature Chemical Biology.

Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy

Xinheng He, H. Xu, Qiu-feng Liu, 2020, Nature Communications.

Insights into divalent cation regulation and G13-coupling of orphan receptor GPR35

Xi Cheng, Xinheng He, Qiu-feng Liu, 2022, Cell discovery.

Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2.

Qiufeng Liu, Jianhua Shen, Yechun Xu, 2017, Journal of medicinal chemistry.

Structural and Thermodynamic Characterization of Protein-Ligand Interactions Formed between Lipoprotein-Associated Phospholipase A2 and Inhibitors.

Yechun Xu, Jianhua Shen, Qiu-feng Liu, 2016, Journal of medicinal chemistry.

Structure-based design of a hyperthermostable AgUricase for hyperuricemia and gout therapy

H. Xu, Qiu-feng Liu, Yi Jiang, 2019, Acta Pharmacologica Sinica.

Structures of full-length glycoprotein hormone receptor signalling complexes

Hualiang Jiang, Shuyang Zhang, Xi Cheng, 2021, Nature.

Structural basis for ligand recognition and G protein-coupling promiscuity of the cholecystokinin A receptor

Qiang Zhao, Xinheng He, Ming-Wei Wang, 2021, bioRxiv.

From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4

Weiliang Zhu, Yechun Xu, Qiu-feng Liu, 2018 .

Structure-Based Discovery of a Series of 5H-Pyrrolo[2,3-b]pyrazine FGFR Kinase Inhibitors

Yechun Xu, Jian Ding, Qiu-feng Liu, 2018, Molecules.

Crystal structure of human FABP4 complexed with ligand 4-Fluoro-3-((4-methoxynaphthalene)-1-sulfonamido) benzoic acid

Weiliang Zhu, Yechun Xu, Qiu-feng Liu, 2018 .

Structure-based design of a hyperthermostable AgUricase for hyperuricemia and gout therapy

H. Xu, Qiu-feng Liu, Yi Jiang, 2019, Acta Pharmacologica Sinica.