Zhonghua Lin

发表

A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies

D. Seshasayee, Jack Bevers, G. Nakamura, 2018, Scientific Reports.

Importance of Cellular Microenvironment and Circulatory Dynamics in B Cell Immunotherapy1

L. Diehl, Yanmei Lu, Y. Meng, 2005, The Journal of Immunology.

Massively parallel single-cell B-cell receptor sequencing enables rapid discovery of diverse antigen-reactive antibodies.

S. Seshagiri, Z. Modrušan, D. Seshasayee, 2019 .

Actin-Bundling Protein L-Plastin Regulates T Cell Activation

D. Danilenko, J. DeVoss, P. Allen, 2010, The Journal of Immunology.

Quilizumab is an Afucosylated Humanized Anti-M1 Prime Therapeutic Antibody

M. Balázs, Lawren C. Wu, Y. Meng, 2014 .

cellular depletion and survival blockade Anti-BR3 antibodies - a new class of B cell immunotherapy combining

D. Danilenko, D. Seshasayee, A. Ebens, 2008 .

Anti-BR3 antibodies: a new class of B-cell immunotherapy combining cellular depletion and survival blockade.

D. Danilenko, D. Seshasayee, A. Ebens, 2007, Blood.

In Vivo Depletion of Lymphotoxin-Alpha Expressing Lymphocytes Inhibits Xenogeneic Graft-versus-Host-Disease

M. Balázs, Zhonghua Lin, E. Chiang, 2012, PloS one.

Restricted epitope specificity determined by variable region germline segment pairing in rodent antibody repertoires

Leonard D. Goldstein, S. Seshagiri, Z. Modrušan, 2020, mAbs.

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

D. Hanahan, S. Baekkeskov, D. Dichek, 1997, Nature Medicine.

Equilibrative Nucleoside Transporter 3 Deficiency Perturbs Lysosome Function and Macrophage Homeostasis

D. Seshasayee, Cécile Chalouni, L. Rangell, 2012, Science.

Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal

D. Seshasayee, G. Nakamura, J. Payandeh, 2018, Proceedings of the National Academy of Sciences.

Conditional Deletion of NF-κB–Inducing Kinase (NIK) in Adult Mice Disrupts Mature B Cell Survival and Activation

M. Balázs, Lawren C. Wu, Zhonghua Lin, 2015, The Journal of Immunology.

Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.

Adam R. Johnson, Z. Modrušan, J. DeVoss, 2017, JCI insight.

Importance of Cellular Microenvironment and Circulatory Dynamics in B Cell Immunotherapy1

L. Diehl, Yanmei Lu, Y. Meng, 2005, The Journal of Immunology.

A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action

Z. Modrušan, G. Nakamura, J. Stinson, 2017, Nature Communications.

Dual B Cell Immunotherapy Is Superior to Individual Anti-CD20 Depletion or BAFF Blockade in Murine Models of Spontaneous or Accelerated Lupus

D. Seshasayee, A. Zarrin, M. Balázs, 2014, Arthritis & rheumatology.

Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model.

Adam R. Johnson, Jun Liang, J. DeVoss, 2017, Bioorganic & medicinal chemistry letters.

Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response

R. Rowntree, D. Seshasayee, R. Vij, 2020, mAbs.

Tetrahydroindazoles as Interleukin-2 Inducible T-Cell Kinase Inhibitors. Part II. Second-Generation Analogues with Enhanced Potency, Selectivity, and Pharmacodynamic Modulation in Vivo.

P. McEwan, J. DeVoss, A. Zarrin, 2015, Journal of medicinal chemistry.

Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood-Brain Barrier

K. Scearce-Levie, K. Gadkar, M. Balázs, 2013, Science Translational Medicine.

Couch Blood-Brain Barrier Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the

K. Scearce-Levie, K. Gadkar, M. Balázs, 2013 .

Development of an ^18F-labeled anti-human CD8 VHH for same-day immunoPET imaging

D. Seshasayee, C. Koth, Jianping Yin, 2022, European Journal of Nuclear Medicine and Molecular Imaging.

Massively parallel single-cell B-cell receptor sequencing enables rapid discovery of diverse antigen-reactive antibodies

Leonard D. Goldstein, S. Seshagiri, Z. Modrušan, 2019, Communications biology.

Massive antibody discovery used to probe structure–function relationships of the essential outer membrane protein LptD

D. Seshasayee, Jack Bevers, G. Nakamura, 2019, eLife.

Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation

Somasekar Seshagiri, Paula Katavolos, Omar Abdel-Wahab, 2012, Science.

Analysis of the effect of promoter type and skin pretreatment on antigen expression and antibody response after gene gun-based immunization

D. Seshasayee, R. Vij, J. T. Koerber, 2018, PloS one.

Polyclonal hyper-IgE mouse model reveals mechanistic insights into antibody class switch recombination

A. Zarrin, S. Warming, V. Dixit, 2013, Proceedings of the National Academy of Sciences.

PILRα Negatively Regulates Mouse Inflammatory Arthritis

S. Kummerfeld, W. Ouyang, J. DeVoss, 2014, The Journal of Immunology.

Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2.

Jane R Kenny, Philippe Bergeron, Tian Jin, 2012, Journal of medicinal chemistry.

An in vivo human-plasmablast enrichment technique allows rapid identification of therapeutic influenza A antibodies.

Henry Chiu, Min Xu, Nancy Chiang, 2013, Cell host & microbe.

Depletion of major pathogenic cells in asthma by targeting CRTh2.

I. Hötzel, J. Payandeh, D. Yan, 2016, JCI insight.

A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies

D. Seshasayee, Jack Bevers, G. Nakamura, 2018, Scientific Reports.

Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice.

Min Xu, Charles Eigenbrot, Meijuan Zhou, 2010, The Journal of clinical investigation.

Massively parallel single-cell B-cell receptor sequencing enables rapid discovery of diverse antigen-reactive antibodies

Leonard D. Goldstein, S. Seshagiri, Z. Modrušan, 2019, Communications Biology.

In vivo antigen-driven plasmablast enrichment in combination with antigen-specific cell sorting to facilitate the isolation of rare monoclonal antibodies from human B cells

D. Seshasayee, G. Nakamura, Zhonghua Lin, 2014, Nature Protocols.

Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury

Ryan L. Kelly, D. Seshasayee, T. Bhangale, 2023, Nature.

Inflammatory Arthritis Negatively Regulates Mouse a PILR

S. Kummerfeld, W. Ouyang, J. DeVoss, 2022 .

Depletion of major pathogenic cells in asthma by targeting CRTh2.

I. Hötzel, J. Payandeh, D. Yan, 2016, JCI insight.