Jone Amuategi

Cholesterol stimulates the lytic activity of Adenylate Cyclase Toxin on lipid membranes by promoting toxin oligomerization and formation of pores with a greater effective size

H. Ostolaza, David González Bullón, K. Uribe, 2021, The FEBS journal.

Membrane Permeabilization by Pore-Forming RTX Toxins: What Kind of Lesions Do These Toxins Form?

David González-Bullón, César Martín, H. Ostolaza, 2019, Toxins.

Four Cholesterol-Recognition Motifs in the Pore-Forming and Translocation Domains of Adenylate Cyclase Toxin Are Essential for Invasion of Eukaryotic Cells and Lysis of Erythrocytes

H. Ostolaza, Jone Amuategi, Rocío Alonso, 2022, International journal of molecular sciences.

The role of four cholesterol-recognition motifs localized between amino acid residues 400-550 in regulating translocation and lytic activity of Adenylate Cyclase Toxin

H. Ostolaza, Jone Amuategi, Rocío Alonso, 2021, bioRxiv.

Membrane-penetrating peptide from the translocation region of Bordetella Adenylate Cyclase Toxin prevents toxin cytotoxicity on target cells

I. de la Arada, H. Ostolaza, Jone Amuategi, 2023, bioRxiv.