P. Bougis

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Penetration of a cardiotoxin into cardiolipin model membranes and its implications on lipid organization.

B. de Kruijff, A. Verkleij, A. Batenburg, 1985, Biochemistry.

A first exploration of the venom of the Buthus occitanus scorpion found in southern France.

P. Bougis, S. Diochot, F. Bosmans, 2014, Toxicon : official journal of the International Society on Toxinology.

Androctonus Toxins Targeting Voltage-Gated Sodium Channels

P. Bougis, M. Martin‐Eauclaire, B. Céard, 2013 .

Characterization of three “Birtoxin-like” toxins from the Androctonus amoreuxi scorpion venom

R. Lebrun, P. Bougis, M. Belghazi, 2011, Peptides.

Precursors of Androctonus australis scorpion neurotoxins. Structures of precursors, processing outcomes, and expression of a functional recombinant toxin II.

P. Bougis, H. Rochat, L. Smith, 1989, The Journal of biological chemistry.

Biochemical, pharmacological and genomic characterisation of Ts IV, an α‐toxin from the venom of the South American scorpion Tityus serrulatus

P. Bougis, H. Rochat, C. Diniz, 1994, FEBS letters.

Promoter structure and intron-exon organization of a scorpion alpha-toxin gene.

M. Marilley, P. Bougis, P. Pasero, 1995, Biochemistry.

Potassium channel blockers from the venom of the Brazilian scorpion Tityus serrulatus ().

P. Bougis, M. D. de Lima, A. Pimenta, 2016, Toxicon : official journal of the International Society on Toxinology.

Potassium Channels Blockers from the Venom of Androctonus mauretanicus mauretanicus

P. Bougis, M. Martin‐Eauclaire, 2012, Journal of toxicology.

A common "hot spot" confers hERG blockade activity to alpha-scorpion toxins affecting K+ channels.

J. Tytgat, H. Satake, L. Possani, 2008, Biochemical pharmacology.

A new Kaliotoxin selective towards Kv1.3 and Kv1.2 but not Kv1.1 channels expressed in oocytes.

J. Tytgat, P. Bougis, M. Belghazi, 2008, Biochemical and biophysical research communications.

Toxin binding to chimeric K+ channels immobilised on a solid nitrocellulose support.

O. Pongs, P. Bougis, C. Legros, 2007, Biochemical and biophysical research communications.

Crystal Structure of Mouse Acetylcholinesterase

P Taylor, P. Taylor, P. Bougis, 1999, The Journal of Biological Chemistry.

Characterization of a new peptide from Tityus serrulatus scorpion venom which is a ligand of the apamin‐binding site

P. Bougis, H. Rochat, C. Legros, 1996, FEBS letters.

SCORPION VENOM NEUROTOXINS: cDNA CLONING AND EXPRESSION

Leonard A. Smith, P. Bougis, H. Rochat, 1989 .

Use of high performance liquid chromatography to demonstrate quantitative variation in components of venom from the scorpion Androctonus australis Hector.

P. Bougis, H. Rochat, M. F. Martin, 1987, Toxicon : official journal of the International Society on Toxinology.

Characterization of elapidae snake venom components using optimized reverse-phase high-performance liquid chromatographic conditions and screening assays for alpha-neurotoxin and phospholipase A2 activities.

P. Bougis, H. Rochat, P. Marchot, 1986, Biochemistry.

The scorpion toxin Bot IX is a potent member of the α‐like family and has a unique N‐terminal sequence extension

P. Bougis, F. Bosmans, M. Martin‐Eauclaire, 2016, FEBS letters.

Crystals of fasciculin 2 from green mamba snake venom. Preparation and preliminary x-ray analysis.

J. Fontecilla-Camps, P. Bougis, M. Le Du, 1989, The Journal of biological chemistry.

Automated Mass Fingerprinting of Venoms in Nanogram Range: Review of Technology

P. Bougis, 2016 .

Individual variability in Tityus serrulatus (Scorpiones, Buthidae) venom elicited by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

P. Bougis, M. D. de Lima, A. Pimenta, 2003, Rapid communications in mass spectrometry : RCM.

Novel structural class of four disulfide-bridged peptides from Tityus serrulatus venom.

P. Bougis, C. Legros, P. Mansuelle, 2003, Biochemical and biophysical research communications.

New analysis of the toxic compounds from the Androctonus mauretanicus mauretanicus scorpion venom.

P. Bougis, N. Oukkache, M. Martin‐Eauclaire, 2008, Toxicon : official journal of the International Society on Toxinology.

A new class of scorpion toxin binding sites related to an A‐type K+ channel: pharmacological characterization and localization in rat brain

S. Kourrich, H. Vacher, P. Bougis, 2001, FEBS letters.

A surface plasmon resonance approach to monitor toxin interactions with an isolated voltage-gated sodium channel paddle motif

P. Bougis, F. Bosmans, M. Martin‐Eauclaire, 2015, The Journal of general physiology.

Use of fusion protein constructs to generate potent immunotherapy and protection against scorpion toxins.

H. Vacher, P. Bougis, C. Legros, 2001, Vaccine.

Moving pieces in a proteomic puzzle: mass fingerprinting of toxic fractions from the venom of Tityus serrulatus (Scorpiones, Buthidae).

R. Stöcklin, P. Bougis, P. Favreau, 2001, Rapid communications in mass spectrometry : RCM.

Functional consequences of deleting the two C-terminal residues of the scorpion toxin BmTX3.

H. Vacher, P. Bougis, H. Darbon, 2003, Biochimica et biophysica acta.

Characterisation of the genes encoding Aa1 isoforms from the scorpion Androctonus australis.

P. Bougis, C. Legros, M. Martin‐Eauclaire, 2003, Toxicon : official journal of the International Society on Toxinology.

Structural Determinants of Fasciculin Specificity for Acetylcholinesterase

P. Taylor, P. Bougis, Z. Radić, 1995 .

Ts1 from the Brazilian scorpion Tityus serrulatus: A half‐century of studies on a multifunctional beta like‐toxin

P. Bougis, M. D. de Lima, M. Martin‐Eauclaire, 2018, Toxicon : official journal of the International Society on Toxinology.

Characterisation of the gene encoding the alpha-toxin Amm V from the scorpion Androctonus mauretanicus mauretanicus.

L. Ouafik, P. Bougis, C. Legros, 2001, Toxicon : official journal of the International Society on Toxinology.

Molecular biology of scorpion toxins active on potassium channels

P. Bougis, C. Legros, M. Martin‐Eauclaire, 1999 .

Purification, characterization and genomic organization of KTX2 from Androctonus australis, a new inhibitor of voltage and calcium activated K+ channel

P. Bougis, H. Rochat, C. Legros, 1996 .

Purification of the main β-toxin from Tityus serrulatus scorpion venom using high-performance liquid chromatography

P. Bougis, M. E. Lima, M. Martin‐Eauclaire, 1992 .

Expanding the scorpion toxin α-KTX 15 family with AmmTX3 from Androctonus mauretanicus

H. Vacher, L. Possani, P. Bougis, 2002 .

Expanding the scorpion toxin alpha-KTX 15 family with AmmTX3 from Androctonus mauretanicus.

H. Vacher, L. Possani, P. Bougis, 2002, European journal of biochemistry.

Achieving automated scorpion venom mass fingerprinting (VMF) in the nanogram range.

S. Granjeaud, P. Bougis, M. Belghazi, 2013, Toxicon : official journal of the International Society on Toxinology.

Tityus serrulatus Hypotensins: a new family of peptides from scorpion venom.

T. Verano-Braga, P. Bougis, M. D. de Lima, 2008, Biochemical and biophysical research communications.

Full characterization of three toxins from the Androctonus amoreuxi scorpion venom.

P. Bougis, C. Legros, M. Belghazi, 2009, Toxicon : official journal of the International Society on Toxinology.

Expression of the standard scorpion alpha-toxin AaH II and AaH II mutants leading to the identification of some key bioactive elements.

H. Vacher, P. Bougis, C. Legros, 2005, Biochimica et biophysica acta.

Characterization of α‐Neurotoxin and Phospholipase A2 Activities from Micrurus Venoms

J. Gutiérrez, P. Bougis, H. Rochat, 1996 .

New "Birtoxin analogs" from Androctonus australis venom.

J. Tytgat, P. Bougis, F. Bosmans, 2005, Biochemical and biophysical research communications.

Involvement of endogenous opioid system in scorpion toxin-induced antinociception in mice

R. Guieu, P. Bougis, N. Sauze, 2010, Neuroscience Letters.

Purification of the main beta-toxin from Tityus serrulatus scorpion venom using high-performance liquid chromatography.

P. Bougis, M. D. de Lima, M. Martin‐Eauclaire, 1992, Toxicon : official journal of the International Society on Toxinology.

Characterization of Amm VIII from Androctonus mauretanicus mauretanicus: a new scorpion toxin that discriminates between neuronal and skeletal sodium channels.

H. Vacher, J. Tytgat, P. Bougis, 2003, The Biochemical journal.

Evidence for a position‐specific deletion as an evolutionary link between long‐ and short‐chain scorpion toxins

P. Bougis, M. Martin‐Eauclaire, B. Céard, 2001, FEBS letters.

A natural anatoxin, Amm VIII, induces neutralizing antibodies against the potent scorpion alpha-toxins.

P. Bougis, M. Martin‐Eauclaire, J. Rosso, 2006, Vaccine.

Analysis by high-performance liquid chromatography of Androctonus mauretanicus mauretanicus (black scorpion) venom.

P. Bougis, M. Martin‐Eauclaire, B. Céard, 1991, Toxicon : official journal of the International Society on Toxinology.

In vivo synergy of cardiotoxin and phospholipase A2 from the elapid snake Naja mossambica mossambica.

P. Bougis, H. Rochat, P. Marchot, 1987, Toxicon : official journal of the International Society on Toxinology.

Characterization by infrared spectroscopy of the interaction of a cardiotoxin with phosphatidic acid and with binary mixtures of phosphatidic acid and phosphatidylcholine.

P. Bougis, M. Pézolet, G. Laroche, 1992, Biochemistry.

Action of lipoprotein lipase on mixed triacylglycerol/phosphatidylcholine monolayers. Activation by apolipoprotein C-II.

P. Kinnunen, R. Verger, A. Gotto, 1983, The Journal of biological chemistry.

On the inhibition of sodium-potassium ATPases by the components of Naja mossambica mossambica venom: evidence for two distinct rat brain sodium-potassium ATPase activities

P. Bougis, H. Rochat, A. Khélif, 1989 .

Genomic organization of the KTX2 gene, encoding a ‘short’ scorpion toxin active on K+ channels

P. Bougis, C. Legros, M. Martin‐Eauclaire, 1997, FEBS letters.

Expression and Activity of Mutants of Fasciculin, a Peptidic Acetylcholinesterase Inhibitor from Mamba Venom*

P. Taylor, P. Bougis, Z. Radić, 1997, The Journal of Biological Chemistry.

MmTX1 and MmTX2 from coral snake venom potently modulate GABAA receptor activity

O. Pongs, J. Gutiérrez, M. Kneussel, 2015, Proceedings of the National Academy of Sciences.

Selective distinction at equilibrium between the two alpha-neurotoxin binding sites of Torpedo acetylcholine receptor by microtitration.

P. Bougis, P. Marchot, P Marchot, 1988, European journal of biochemistry.

Conformation of free and phospholipid-bound cardiotoxins from Naja mossambica mossambica by laser Raman spectroscopy

J. Dufourcq, P. Bougis, M. Pézolet, 1982 .

Perturbations of charged phospholipid bilayers induced by melittin and cardiotoxins. A fluorescence, differential scanning calorimetry and Raman spectroscopy study.

J. Dufourcq, P. Bougis, M. Pézolet, 1982, Biochimie.

Model of interaction between a cardiotoxin and dimyristoylphosphatidic acid bilayers determined by solid-state 31P NMR spectroscopy.

M. Auger, P. Bougis, M. Pézolet, 1996, Biophysical journal.

Penetration of phospholipid monolayers by cardiotoxins.

R. Verger, G. Piéroni, P. Bougis, 1981, Biochemistry.

Mixed phospholipid-cardiotoxin monomolecular films studied by intrinsic polarized surface fluorescence.

J. Teissié, R. Verger, G. Piéroni, 1987, Biochemical and biophysical research communications.

Sequence of horse pancreatic lipase as determined by protein and cDNA sequencing. Implications for p-nitrophenyl acetate hydrolysis by pancreatic lipases.

P. Bougis, B. Kerfelec, J. Bonicel, 1992, European journal of biochemistry.

Crystal Structure of Mouse Acetylcholinesterase

P. Taylor, P. Bougis, Y. Bourne, 1999, The Journal of Biological Chemistry.

Structural basis of α-scorpion toxin action on Nav channels

A. Rohou, C. Arthur, C. Ciferri, 2019, Science.

Binding of 125I-fasciculin to rat brain acetylcholinesterase. The complex still binds diisopropyl fluorophosphate.

Yong-hua Ji, P. Bougis, P. Mansuelle, 1993, The Journal of biological chemistry.

Serotherapy against Voltage-Gated Sodium Channel-Targeting α-Toxins from Androctonus Scorpion Venom

P. Bougis, F. Laraba-Djebari, D. Hammoudi-Triki, 2019, Toxins.

Elapidae Toxins: The Fasciculins, and their Interaction with Acetylcholinesterase

P. Bougis, P. Marchot, 2000 .

Inhibition of mouse acetylcholinesterase by fasciculin: crystal structure of the complex and mutagenesis of fasciculin.

P Taylor, P. Taylor, P. Bougis, 1998, Toxicon : official journal of the International Society on Toxinology.

Tetrameric assembly and peripheral site-occluding loop of mouse acetylcholinesterase

P. Taylor, P. Bougis, Y. Bourne, 1998, Journal of Physiology-Paris.

Biotinylation of the tyrosine residues of fasciculin

P. Taylor, P. Bougis, P. Marchot, 1998, Journal of Physiology-Paris.

Fasciculin Inhibition of Mouse Acetylcholinesterase

P. Taylor, P. Bougis, Jonathan R Eads, 1998 .

Determination of the nuclear-magnetic-resonance solution structure of cardiotoxin CTX IIb from Naja mossambica mossambica.

K. Wüthrich, P. Bougis, J. O'Connell, 1993, European journal of biochemistry.

Localization of the toxic site of Naja mossambica cardiotoxins: small synthetic peptides express an in vivo lethality.

P. Bougis, H. Rochat, P. Marchot, 1988, Biochemical and biophysical research communications.

Sequence-specific 1H-NMR assignments and determination of the secondary structure in aqueous solution of the cardiotoxins CTXIIa and CTXIIb from Naja mossambica mossambica.

K. Wüthrich, G. Otting, P. Bougis, 1987, European journal of biochemistry.

Production of active, insect-specific scorpion neurotoxin in yeast.

B. Svensson, P. Bougis, S. Cestèle, 1994, European journal of biochemistry.

Generating a High Affinity Scorpion Toxin Receptor in KcsA-Kv1.3 Chimeric Potassium Channels*

O. Pongs, P. Bougis, C. Legros, 2000, The Journal of Biological Chemistry.

Characterization of the first K⁺ channel blockers from the venom of the Moroccan scorpion Buthus occitanus Paris.

R. Lebrun, P. Bougis, M. Belghazi, 2013, Toxicon : official journal of the International Society on Toxinology.

Evidence for a new class of scorpion toxins active against K+ channels

P. Bougis, C. Legros, P E Bougis, 1998, FEBS letters.

Comparative analyses and implications for antivenom serotherapy of four Moroccan scorpion Buthus occitanus venoms: Subspecies tunetanus, paris, malhommei, and mardochei

P. Bougis, M. D. de Lima, M. Martin‐Eauclaire, 2017, Toxicon : official journal of the International Society on Toxinology.

1.9-A resolution structure of fasciculin 1, an anti-acetylcholinesterase toxin from green mamba snake venom.

J C Fontecilla-Camps, J. Fontecilla-Camps, P. Bougis, 1993, The Journal of biological chemistry.

Structural basis of alpha-scorpion toxin action on Navchannels.

A. Rohou, C. Arthur, C. Ciferri, 2019 .

Engineering-specific pharmacological binding sites for peptidyl inhibitors of potassium channels into KcsA.

Olaf Pongs, O. Pongs, P. Bougis, 2002, Biochemistry.

1H nuclear-magnetic-resonance studies of the three-dimensional structure of the cardiotoxin CTXIIb from Naja mossambica mossambica in aqueous solution and comparison with the crystal structures of homologous toxins.

K. Wüthrich, W. Braun, P. Bougis, 1988, European journal of biochemistry.

Homologues of a K+ channel blocker α-dendrotoxin: characterization of synaptosomal binding sites and their coupling to elevation of cytosolic free calcium concentration

D. Nicholls, J. Dolly, P. Bougis, 1990, Neurochemistry International.

Conformational Flexibility of the Acetylcholinesterase Tetramer Suggested by X-ray Crystallography*

J. Grassi, P. Bougis, Y. Bourne, 1999, The Journal of Biological Chemistry.

Selective loss of binding sites for the iodinated alpha-neurotoxin I from Naja mossambica mossambica venom upon enzymatic deglycosylation of Torpedo electric organ membranes.

P. Bougis, P. Marchot, C. Ronin, 1988, European Journal of Biochemistry.

Influence of a NH2‐terminal extension on the activity of KTX2, a K+ channel blocker purified from Androctonus australis scorpion venom

E. Feyfant, P. Bougis, H. Rochat, 1997, FEBS letters.

Structure of fasciculin 2 from green mamba snake venom: evidence for unusual loop flexibility.

J. Navaza, J. Fontecilla-Camps, P. Bougis, 1995, Acta crystallographica. Section D, Biological crystallography.

Dipeptidyl‐peptidase‐like‐proteins confer high sensitivity to the scorpion toxin AmmTX3 to Kv4‐mediated A‐type K+ channels

B. Rudy, E. Dvoretskova, P. Bougis, 2013, The Journal of physiology.

Monitoring the purification by high-performance liquid chromatography of cardiotoxins from Naja mossambica mossambica using phase-sensitive two-dimensional nuclear magnetic resonance.

K. Wüthrich, G. Otting, P. Bougis, 1987, European journal of biochemistry.

Two neutralizing monoclonal antibodies specific for Naja nigricollis cardiotoxin: preparation, characterization and localization of the epitopes.

A. Ménez, P. Bougis, P. Fromageot, 1986, Molecular immunology.