S. Corbalán-García

发表

C2 domain of protein kinase C alpha: elucidation of the membrane docking surface by site-directed fluorescence and spin labeling.

J. Falke, S. Kohout, S. Corbalán-García, 2003, Biochemistry.

A comparison of the membrane binding properties of C1B domains of PKCgamma, PKCdelta, and PKCepsilon.

S. Corbalán-García, J. Gomez-Fernandez, Sonia Sánchez-Bautista, 2009, Biophysical journal.

Diacylglycerols as activators of protein kinase C (Review)

S. Corbalán-García, J. Gomez-Fernandez, A. Torrecillas, 2004 .

The C2 domain of protein kinase calpha is directly involved in the diacylglycerol-dependent binding of the C1 domain to the membrane.

S. Corbalán-García, J. Gomez-Fernandez, P. Conesa‐Zamora, 2000, Biochimica et biophysica acta.

Identification of the mitogen-activated protein kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2

D. Bar-Sagi, K. Degenhardt, S. Corbalán-García, 1996, Molecular and cellular biology.

Insulin-induced dissociation of Sos from Grb2 does not contribute to the down regulation of Ras activation.

D. Bar-Sagi, K. Degenhardt, S. Corbalán-García, 1996, Oncogene.

Curcumin disorders 1,2-dipalmitoyl-sn-glycero-3-phosphocholine membranes and favors the formation of nonlamellar structures by 1,2-dielaidoyl-sn-glycero-3-phosphoethanolamine.

A. Ausili, S. Corbalán-García, J. Gomez-Fernandez, 2010, The journal of physical chemistry. B.

Signaling through C2 domains: more than one lipid target.

S. Corbalán-García, J. Gomez-Fernandez, 2014, Biochimica et biophysica acta.

A kinetic study of an unstable enzyme measured through coupling reactions. Application to the self-inactivation of detergent-solubilized Ca(2+)-ATPase from sarcoplasmic reticulum.

R. Varón, F. García-Cánovas, S. Corbalán-García, 1993, Biochimica et biophysica acta.

The PtdIns(4,5)P2 ligand itself influences the localization of PKCalpha in the plasma membrane of intact living cells.

S. Corbalán-García, J. Gomez-Fernandez, C. Marín‐Vicente, 2008, Journal of molecular biology.

Interaction of the C2 domain from protein kinase C(epsilon) with model membranes.

S. Corbalán-García, J. Gomez-Fernandez, Sonia Sánchez-Bautista, 2007, Biochemistry.

Study of the secondary structure of the C-terminal domain of the antiapoptotic protein bcl-2 and its interaction with model membranes.

S. Corbalán-García, J. Gomez-Fernandez, M. del Mar Martínez-Senac, 2000, Biochemistry.

Effects of the anti-neoplastic agent ET-18-OCH3 and some analogs on the biophysical properties of model membranes.

F. Mollinedo, C. Gajate, S. Corbalán-García, 2006, International journal of pharmaceutics.

Membrane docking mode of the C2 domain of PKCε: an infrared spectroscopy and FRET study.

A. Ausili, H. Elwing, S. Corbalán-García, 2013, Biochimica et biophysica acta.

Interaction of the C-terminal domain of Bcl-2 family proteins with model membranes.

A. Ausili, S. Corbalán-García, J. Gomez-Fernandez, 2007, Biochimica et biophysica acta.

The C2 domains of classical and novel PKCs as versatile decoders of membrane signals

S. Corbalán-García, J. Gomez-Fernandez, 2010, BioFactors.

The interaction of the Bax C-terminal domain with negatively charged lipids modifies the secondary structure and changes its way of insertion into membranes.

A. Ausili, S. Corbalán-García, J. Gomez-Fernandez, 2008, Journal of structural biology.

The structure of the C-terminal domain of the pro-apoptotic protein Bak and its interaction with model membranes.

S. Corbalán-García, J. Gomez-Fernandez, M. M. Martínez-Senac, 2002, Biophysical journal.

The binding of different model membranes with PKCε C2 domain is not dependent on membrane curvature but affects the sequence of events during unfolding.

A. Ausili, S. Corbalán-García, J. Gomez-Fernandez, 2021, Archives of biochemistry and biophysics.

Edelfosine is incorporated into rafts and alters their organization.

A. Ausili, F. Mollinedo, C. Gajate, 2008, The journal of physical chemistry. B.

A comparative study of the activation of protein kinase C alpha by different diacylglycerol isomers.

S. Corbalán-García, J. Gomez-Fernandez, V. Micol, 1999, The Biochemical journal.

The C2 domains of classical PKCs are specific PtdIns(4,5)P2-sensing domains with different affinities for membrane binding.

S. Corbalán-García, J. Gomez-Fernandez, M. Guerrero-Valero, 2007, Journal of molecular biology.

A comparative study of the effect of the antineoplastic ether lipid 1-O-octadecyl-2-O-methyl-glycero-3-phosphocholine and some homologous compounds on PKCα and PKCɛ

F. Mollinedo, S. Corbalán-García, J. Gomez-Fernandez, 2005 .

Correlation between the effect of the anti-neoplastic ether lipid 1-O-octadecyl-2-O-methyl-glycero-3-phosphocholine on the membrane and the activity of protein kinase Calpha.

S. Corbalán-García, J. Gomez-Fernandez, P. Conesa‐Zamora, 2001, European journal of biochemistry.

The simultaneous production of phosphatidic acid and diacylglycerol is essential for the translocation of protein kinase Cepsilon to the plasma membrane in RBL-2H3 cells.

S. Corbalán-García, J. Gomez-Fernandez, Maria Jose Lopez-Andreo, 2003, Molecular biology of the cell.

Deciphering the Role and Signaling Pathways of PKCα in Luminal A Breast Cancer Cells

Z. Szallasi, R. López-Nicolás, S. Corbalán-García, 2022, International journal of molecular sciences.

The vertical location of α-tocopherol in phosphatidylcholine membranes is not altered as a function of the degree of unsaturation of the fatty acyl chains.

A. Ausili, S. Corbalán-García, J. Gomez-Fernandez, 2017, Physical chemistry chemical physics : PCCP.

Intramolecular distances within the Ca(2+)-ATPase from sarcoplasmic reticulum as estimated through fluorescence energy transfer between probes.

S. Corbalán-García, J. Gomez-Fernandez, J. Teruel, 1993, European journal of biochemistry.

Redox state of coenzyme Q10 determines its membrane localization.

A. Ausili, S. Corbalán-García, J. Gomez-Fernandez, 2008, The journal of physical chemistry. B.

Ca2+ bridges the C2 membrane‐binding domain of protein kinase Cα directly to phosphatidylserine

N. Verdaguer, S. Corbalán-García, J. Gomez-Fernandez, 1999 .

Structural study of the catalytic domain of PKCζ using infrared spectroscopy and two‐dimensional infrared correlation spectroscopy

A. Kazaks, S. Corbalán-García, J. Gomez-Fernandez, 2006, The FEBS journal.

Diacylglycerols, multivalent membrane modulators.

S. Corbalán-García, J. Gomez-Fernandez, 2007, Chemistry and physics of lipids.

Protein kinase C regulatory domains: the art of decoding many different signals in membranes.

S. Corbalán-García, J. Gomez-Fernandez, 2006, Biochimica et biophysica acta.

Role of the Ca2+/Phosphatidylserine Binding Region of the C2 Domain in the Translocation of Protein Kinase Cα to the Plasma Membrane*

S. Bolsover, S. Corbalán-García, J. Gomez-Fernandez, 2003, The Journal of Biological Chemistry.

Structure of the C2 domain from novel protein kinase Cepsilon. A membrane binding model for Ca(2+)-independent C2 domains.

N. Verdaguer, S. Corbalán-García, J. Gomez-Fernandez, 2001, Journal of molecular biology.

Anticancer Agent Edelfosine Exhibits a High Affinity for Cholesterol and Disorganizes Liquid-Ordered Membrane Structures.

A. Ausili, S. Corbalán-García, A. Torrecillas, 2018, Langmuir : the ACS journal of surfaces and colloids.

C2 Domains of Protein Kinase C Isoforms α, β, and γ: Activation Parameters and Calcium Stoichiometries of the Membrane-Bound State

Joseph J. Falke, J. Falke, S. Corbalán-García, 2002 .

Regulation of Sos Activity by Intramolecular Interactions

D. Bar-Sagi, S. Corbalán-García, D. Galron, 1998, Molecular and Cellular Biology.

The role of the PH domain in the signal‐dependent membrane targeting of Sos

D. Bar-Sagi, S. Corbalán-García, R.-H. Chen, 1997, The EMBO journal.

The interaction of the Bax C-terminal domain with membranes is influenced by the presence of negatively charged phospholipids.

A. Ausili, S. Corbalán-García, J. Gomez-Fernandez, 2009, Biochimica et biophysica acta.

Membrane Binding C2-Like Domains

N. Verdaguer, S. Corbalán-García, J. Gomez-Fernandez, 2011 .

Phosphatidylinositol Monophosphates Regulate Optimal Vav1 Signaling Output

X. Bustelo, M. Vicente-Manzanares, S. Corbalán-García, 2019, Cells.

Crystal structure of the C-terminal four-helix bundle of the potassium channel KCa3.1

S. Hubbard, S. Corbalán-García, T. Ji, 2018, PloS one.

Involvement of an arginyl residue in the nucleotide-binding site of Ca(2+)-ATPase from sarcoplasmic reticulum as seen by reaction with phenylglyoxal.

S. Corbalán-García, J. Gomez-Fernandez, J. Teruel, 1996, The Biochemical journal.

PKC, a key switch in cancer signaling pathways

R. López-Nicolás, S. Corbalán-García, J. Gomez-Fernandez, 2015 .

Modulation of the membrane orientation and secondary structure of the C-terminal domains of Bak and Bcl-2 by lipids.

E. Goormaghtigh, S. Corbalán-García, J. Gomez-Fernandez, 2005, Biochemistry.

Structural characterization of the C2 domains of classical isozymes of protein kinase C and novel protein kinase Cε by using infrared spectroscopy

S. Corbalán-García, J. Gomez-Fernandez, J. García-García, 2003 .

Structural characterization of the C2 domain of novel protein kinase Cepsilon.

S. Corbalán-García, J. Gomez-Fernandez, J. García-García, 2001, European journal of biochemistry.

ATP enhances neuronal differentiation of PC12 cells by activating PKCα interactions with cytoskeletal proteins.

M. Savitski, R. Zubarev, M. L. Nielsen, 2011, Journal of proteome research.

KIR+ CD8+ T Lymphocytes in Cancer Immunosurveillance and Patient Survival: Gene Expression Profiling

A. Minguela, S. Corbalán-García, M. Álvarez-López, 2020, Cancers.

C2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound state.

J. Falke, S. Corbalán-García, J. Gomez-Fernandez, 2002, Biochemistry.

Molecular mechanisms of PKCalpha localization and activation by arachidonic acid. The C2 domain also plays a role.

R. López-Nicolás, S. Corbalán-García, J. Gomez-Fernandez, 2006, Journal of molecular biology.

Interaction of vitamin K1 and vitamin K2 with DMPC and their location in the membrane.

A. Ausili, S. Corbalán-García, J. Gomez-Fernandez, 2020, Langmuir : the ACS journal of surfaces and colloids.

Both idebenone and idebenol are localized near the lipid-water interface of the membrane and increase its fluidity.

S. Corbalán-García, J. Gomez-Fernandez, A. Torrecillas, 2016, Biochimica et biophysica acta.

An infrared spectroscopic study of the secondary structure of protein kinase C alpha and its thermal denaturation.

S. Corbalán-García, J. Gomez-Fernandez, A. Torrecillas, 2004, Biochemistry.

Characterization of the membrane binding mode of the C2 domain of PKC epsilon.

S. Corbalán-García, J. Gomez-Fernandez, Juan C Gómez-Fernández, 2003, Biochemistry.

Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1

J. Pous, N. Verdaguer, S. Corbalán-García, 2013, Proceedings of the National Academy of Sciences.

The C2 domain of PKCalpha is a Ca2+ -dependent PtdIns(4,5)P2 sensing domain: a new insight into an old pathway.

Consuelo Marín-Vicente, S. Corbalán-García, J. Gomez-Fernandez, 2006, Journal of molecular biology.

Characterization of ruthenium red-binding sites of the Ca(2+)-ATPase from sarcoplasmic reticulum and their interaction with Ca(2+)-binding sites.

S. Corbalán-García, J. Gomez-Fernandez, J. Teruel, 1992, The Biochemical journal.

Membrane docking of the C2 domain from protein kinase Cα as seen by polarized ATR-IR. The role of PIP₂.

A. Ausili, D. Marsh, S. Corbalán-García, 2011, Biochimica et biophysica acta.

Membrane docking of the C 2 domain from protein kinase C α as seen by polarized ATR-IR . The role of PIP 2

A. Ausili, D. Marsh, S. Corbalán-García, 2011 .

The C2 domains of classical/conventional PKCs are specific PtdIns(4,5)P(2)-sensing domains.

S. Corbalán-García, J. Gomez-Fernandez, M. Guerrero-Valero, 2007, Biochemical Society transactions.

Structural and mechanistic insights into the association of PKCα-C2 domain to PtdIns(4,5)P2

N. Verdaguer, S. Corbalán-García, J. Gomez-Fernandez, 2009, Proceedings of the National Academy of Sciences.

The ATP-dependent membrane localization of protein kinase Calpha is regulated by Ca2+ influx and phosphatidylinositol 4,5-bisphosphate in differentiated PC12 cells.

S. Corbalán-García, J. Gomez-Fernandez, C. Marín‐Vicente, 2005, Molecular biology of the cell.

Role of the lysine-rich cluster of the C2 domain in the phosphatidylserine-dependent activation of PKCalpha.

S. Corbalán-García, J. Gomez-Fernandez, J. A. Rodríguez-Alfaro, 2004, Journal of molecular biology.

A New Phosphatidylinositol 4,5-Bisphosphate-binding Site Located in the C2 Domain of Protein Kinase Cα*

S. Corbalán-García, J. Gomez-Fernandez, J. A. Rodríguez-Alfaro, 2003, The Journal of Biological Chemistry.

Additional binding sites for anionic phospholipids and calcium ions in the crystal structures of complexes of the C2 domain of protein kinase calpha.

R. Eritja, N. Verdaguer, S. Corbalán-García, 2002, Journal of molecular biology.

Determination of the calcium-binding sites of the C2 domain of protein kinase Calpha that are critical for its translocation to the plasma membrane.

S. Corbalán-García, J. Gomez-Fernandez, J. A. Rodríguez-Alfaro, 1999, The Biochemical journal.

Capsaicin Fluidifies the Membrane and Localizes Itself near the Lipid-Water Interface.

A. Ausili, S. Corbalán-García, J. Gomez-Fernandez, 2015, ACS chemical neuroscience.

A comparative study of the activation of protein kinase C alpha by different diacylglycerol isomers.

S. Corbalán-García, J. Gomez-Fernandez, V. Micol, 1999, The Biochemical journal.

The C1B domains of novel PKCε and PKCη have a higher membrane binding affinity than those of the also novel PKCδ and PKCθ.

S. Corbalán-García, J. Gomez-Fernandez, A. L. Egea-Jimenez, 2014, Biochimica et biophysica acta.

Classical protein kinases C are regulated by concerted interaction with lipids: the importance of phosphatidylinositol-4,5-bisphosphate

S. Corbalán-García, J. Gomez-Fernandez, 2013, Biophysical Reviews.

Phosphatidylinositol 4,5-Bisphosphate Decreases the Concentration of Ca2+, Phosphatidylserine and Diacylglycerol Required for Protein Kinase C α to Reach Maximum Activity

S. Corbalán-García, J. Gomez-Fernandez, Á. Pérez-Lara, 2013, PloS one.

The membrane binding kinetics of full-length PKCα is determined by membrane lipid composition.

A. Ausili, S. Corbalán-García, Á. Pérez-Lara, 2012, Biochimica et biophysica acta.

Structural characterization of the C 2 domains of classical isozymes of protein kinase C and novel protein kinase C ε by using infrared spectroscopy

S. Corbalán-García, J. Gomez-Fernandez, J. García-García, 2014 .

Quartz crystal microbalance with dissipation monitoring and the real-time study of biological systems and macromolecules at interfaces

A. Ausili, H. Elwing, S. Corbalán-García, 2012 .

“ Additional binding sites for anionic phospholipids and Ca 2 + ions in the crystal structures of complexes of the C 2 domain of protein kinase

R. Eritja, N. Verdaguer, S. Corbalán-García, 2016 .

Calorimetric study of the interaction of the C2 domains of classical protein kinase C isoenzymes with Ca2+ and phospholipids.

M. Menéndez, S. Corbalán-García, J. Gomez-Fernandez, 2004, Biochemistry.

Identification of the phosphatidylserine binding site in the C2 domain that is important for PKC alpha activation and in vivo cell localization.

S. Corbalán-García, J. Gomez-Fernandez, P. Conesa‐Zamora, 2001, Biochemistry.

Structural characterization of the Rabphilin-3A–SNAP25 interaction

N. Verdaguer, S. Corbalán-García, J. Gomez-Fernandez, 2017, Proceedings of the National Academy of Sciences.

Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine.

N. Verdaguer, S. Corbalán-García, J. Gomez-Fernandez, 1999, The EMBO journal.

X-ray diffraction and NMR data for the study of the location of idebenone and idebenol in model membranes

S. Corbalán-García, J. Gomez-Fernandez, A. Torrecillas, 2016, Data in Brief.

Extensive proteolytic digestion of the (Ca2+ + Mg2+)-ATPase from sarcoplasmic reticulum leads to a highly hydrophobic proteinaceous residue with a mainly alpha-helical structure.

S. Corbalán-García, J. Gomez-Fernandez, J. Villalaín, 1994, Biochemistry.

Classical protein kinases C are regulated by concerted interaction with lipids: the importance of phosphatidylinositol-4,5-bisphosphate

S. Corbalán-García, J. Gomez-Fernandez, 2014, Biophysical Reviews.

Phosphatidylinositol-4,5-Bisphosphate Enhances Anionic Lipid Demixing by the C2 Domain of PKCα

S. Corbalán-García, J. Gomez-Fernandez, Á. Pérez-Lara, 2014, PloS one.

Retinoic acid binds to the C2-domain of protein kinase C(alpha).

N. Verdaguer, S. Corbalán-García, J. Gomez-Fernandez, 2003, Biochemistry.

PKCε controls the fusion of secretory vesicles in mast cells in a phosphatidic acid-dependent mode.

S. Corbalán-García, J. Gomez-Fernandez, David López-Martínez, 2021, International journal of biological macromolecules.

Structural study of the C2 domains of the classical PKC isoenzymes using infrared spectroscopy and two-dimensional infrared correlation spectroscopy.

S. Corbalán-García, J. Gomez-Fernandez, A. Torrecillas, 2003, Biochemistry.

Location of N-cyclohexyl-N'-(4-dimethyl-amino-alpha-naphthyl)carbodiimide- binding site in sarcoplasmic reticulum Ca2+-transporting ATPase.

S. Corbalán-García, J. Gomez-Fernandez, J. Teruel, 1998, European journal of biochemistry.

The C1B domains of novel PKCε and PKCη have a higher membrane binding affinity than those of the also novel PKCδ and PKCθ.

S. Corbalán-García, J. Gomez-Fernandez, A. L. Egea-Jimenez, 2014, Biochimica et biophysica acta.