Keigo Kumagai

发表

Molecular machinery for non-vesicular trafficking of ceramide

Satoshi Yasuda, S. Yasuda, K. Hanada, 2003, Nature.

Structure, functions and regulation of CERT, a lipid‐transfer protein for the delivery of ceramide at the ER–Golgi membrane contact sites

K. Hanada, Keigo Kumagai, 2019, FEBS letters.

CERT Mediates Intermembrane Transfer of Various Molecular Species of Ceramides*

S. Yasuda, K. Hanada, Keigo Kumagai, 2005, Journal of Biological Chemistry.

Efficient Trafficking of Ceramide from the Endoplasmic Reticulum to the Golgi Apparatus Requires a VAMP-associated Protein-interacting FFAT Motif of CERT*

K. Hanada, Keigo Kumagai, M. Kawano, 2006, Journal of Biological Chemistry.

CERT and intracellular trafficking of ceramide.

K. Hanada, Keigo Kumagai, M. Kawano, 2007, Biochimica et biophysica acta.

Interorganelle Trafficking of Ceramide Is Regulated by Phosphorylation-dependent Cooperativity between the PH and START Domains of CERT*

K. Hanada, Keigo Kumagai, M. Kawano, 2007, Journal of Biological Chemistry.

Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide

Soichi Wakatsuki, Ryuichi Kato, T. Yamaji, 2008, Proceedings of the National Academy of Sciences.

Protein Phosphatase 2Cϵ Is an Endoplasmic Reticulum Integral Membrane Protein That Dephosphorylates the Ceramide Transport Protein CERT to Enhance Its Association with Organelle Membranes*

S. Saito, K. Hanada, Keigo Kumagai, 2008, Journal of Biological Chemistry.

CERT-mediated trafficking of ceramide.

T. Yamaji, K. Hanada, Keigo Kumagai, 2009, Biochimica et biophysica acta.

Phosphoregulation of the Ceramide Transport Protein CERT at Serine 315 in the Interaction with VAMP-associated Protein (VAP) for Inter-organelle Trafficking of Ceramide in Mammalian Cells*

K. Hanada, Keigo Kumagai, Miyuki Kawano-Kawada, 2014, The Journal of Biological Chemistry.

Two sphingolipid transfer proteins, CERT and FAPP2: Their roles in sphingolipid metabolism

T. Yamaji, K. Hanada, Keigo Kumagai, 2008, IUBMB life.

Effects of FKBP12 and type II BMP receptors on signal transduction by ALK2 activating mutations associated with genetic disorders.

A. Bullock, Keigo Kumagai, S. Ohte, 2018, Bone.

Hyperosmotic Stress Induces Phosphorylation of CERT and Enhances Its Tethering throughout the Endoplasmic Reticulum

T. Yamaji, K. Hanada, Keigo Kumagai, 2022, International journal of molecular sciences.

Sphingomyelin-dependence of cholesterol efflux mediated by ABCG1s⃞ Published, JLR Papers in Press, August 29, 2007.

K. Ueda, N. Kioka, K. Hanada, 2007, Journal of Lipid Research.

Involvement of a Cluster of Basic Amino Acids in Phosphorylation-Dependent Functional Repression of the Ceramide Transport Protein CERT

T. Yamaji, K. Hanada, Keigo Kumagai, 2022, International journal of molecular sciences.

Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer.

K. Hanada, Keigo Kumagai, S. Wakatsuki, 2010, Journal of molecular biology.

Both the N- and C- terminal regions of the Chlamydial inclusion protein D (IncD) are required for interaction with the pleckstrin homology domain of the ceramide transport protein CERT.

C. Elwell, J. Engel, K. Hanada, 2018, Biochemical and biophysical research communications.

Molecular Mechanism of Ceramide Trafficking from the Endoplasmic Reticulum to the Golgi Apparatus in Mammalian Cells

K. Hanada, Keigo Kumagai, M. Kawano, 2006 .

Pleckstrin homology domain of p210 BCR‐ABL interacts with cardiolipin to regulate its mitochondrial translocation and subsequent mitophagy

M. Naito, Yoshiro Saito, S. Funamoto, 2018, Genes to cells : devoted to molecular & cellular mechanisms.

Chlamydial Infection-Dependent Synthesis of Sphingomyelin as a Novel Anti-Chlamydial Target of Ceramide Mimetic Compounds

M. Kataoka, K. Hanada, Keigo Kumagai, 2022, International journal of molecular sciences.

Crystal Structure and Magnetic Properties of New Cubic Quaternary Compounds RT2Sn2Zn18 (R = La, Ce, Pr, and Nd, and T = Co and Fe)

P. Bordet, T. Mizushima, T. Kuwai, 2015 .

Dense Kondo Effect in Caged Compound CeRu2Zn20

T. Mizushima, T. Kuwai, Y. Isikawa, 2013 .

Enhancement of the curie temperature due to the coupling between Fe itinerant electrons and Dy localized electrons in DyFe2Zn20

T. Mizushima, T. Kuwai, Y. Isikawa, 2012, 1210.7922.

Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT

K. Hanada, Keigo Kumagai, H. Hanzawa, 2019, Communications Chemistry.

Reconstitution assay system for ceramide transport with semi-intact cells.

K. Hanada, Keigo Kumagai, M. Nishijima, 2012, Methods in cell biology.

Casein kinase I{gamma}2 down-regulates trafficking of ceramide in the synthesis of sphingomyelin.

K. Hanada, Keigo Kumagai, M. Nishijima, 2009, Molecular biology of the cell.

Natural Ligand-Mimetic and Nonmimetic Inhibitors of the Ceramide Transport Protein CERT

K. Hanada, Keigo Kumagai, S. Sakai, 2022, International journal of molecular sciences.

Sphingomyelin Is Essential for the Structure and Function of the Double-Membrane Vesicles in Hepatitis C Virus RNA Replication Factories

S. Ichinose, M. Muramatsu, T. Wakita, 2020, Journal of Virology.

Chlamydia trachomatis‐infected human cells convert ceramide to sphingomyelin without sphingomyelin synthases 1 and 2

T. Yamaji, K. Hanada, Keigo Kumagai, 2019, FEBS letters.

Decreased Ceramide Transport Protein (CERT) Function Alters Sphingomyelin Production following UVB Irradiation*

K. Hanada, Keigo Kumagai, M. Kawano, 2008, Journal of Biological Chemistry.

Structural Basis for the Golgi Association by the Pleckstrin Homology Domain of the Ceramide Trafficking Protein (CERT)*

I. Shimada, Hideo Takahashi, T. Sugiki, 2012, The Journal of Biological Chemistry.

Phosphoinositide binding by the PH domain in ceramide transfer protein (CERT) is inhibited by hyperphosphorylation of an adjacent serine-repeat motif

T. Fujiwara, C. Kojima, I. Shimada, 2018, The Journal of Biological Chemistry.

Stereoselective synthesis and structure-activity relationship of novel ceramide trafficking inhibitors. (1R,3R)-N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamide and its analogues.

S. Yasuda, K. Hanada, Keigo Kumagai, 2003, Journal of medicinal chemistry.

Genes to Cells

M. Naito, S. Funamoto, K. Hanada, 2018 .