S. Fix

发表

Identification of the first trans-(3R,4R)- dimethyl-4-(3-hydroxyphenyl)piperidine derivative to possess highly potent and selective opioid kappa receptor antagonist activity.

F I Carroll, S W Mascarella, James B. Thomas, 2001, Journal of medicinal chemistry.

Identification of (3R)-7-hydroxy-N-((1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)- 3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl)-1,2,3,4-tetrahydro- 3-isoquinolinecarboxamide as a novel potent and selective opioid kappa receptor antagonist.

James B. Thomas, S. Mascarella, F. Carroll, 2003, Journal of medicinal chemistry.

Synthesis of long-chain amide analogs of the cannabinoid CB1 receptor antagonist N-(piperidinyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716) with unique binding selectivities and pharmacological activities.

James B. Thomas, S. Fix, B. Thomas, 2005, Bioorganic & medicinal chemistry.

Importance of phenolic address groups in opioid kappa receptor selective antagonists.

James B. Thomas, S. Mascarella, F. Carroll, 2004, Journal of medicinal chemistry.

α-[Amino(4-aminophenyl)thio]methylene-2-(trifluoromethyl)benzeneacetonitrile; Configurational equilibria in solution.

J. Deschamps, L. Brieaddy, S. Mascarella, 2021, Bioorganic chemistry.

Deuterated batracylin: deuterium-hydrogen exchange during synthesis and mass spectral analysis

S. Fix, H. Seltzman, P. Risbood, 2011 .

Synthesis of 9β-methyl-2-alkyl-7-oxo-5-arylmorphans

James B. Thomas, L. Brieaddy, S. Mascarella, 1998 .

Synthesis and antihormonal properties of novel 11β-benzoxazole-substituted steroids.

S. Fix, C. Cook, Chunyang Jin, 2012, Bioorganic & medicinal chemistry letters.

A stereoselective synthetic approach to N-alkyl-4β-methyl-5-phenylmorphans

James B. Thomas, S. Mascarella, F. Carroll, 1999 .