F. Cornelius

发表

Crystal structure of the sodium–potassium pump at 2.4 Å resolution

C. Toyoshima, Takehiro Shinoda, H. Ogawa, 2009, Nature.

First crystal structures of Na+,K+-ATPase: new light on the oldest ion pump.

C. Toyoshima, R. Kanai, F. Cornelius, 2011, Structure.

Mechanism of Mg 2þ Binding in the Na þ ,K þ -ATPase

P. Kuchel, P. Sebban, F. Cornelius, 2009 .

Interaction of FXYD10 (PLMS) with Na,K-ATPase from Shark Rectal Glands

H. Vorum, F. Cornelius, Y. Mahmmoud, 2005, Journal of Biological Chemistry.

Themes in Ion Pump Regulation

F. Cornelius, Y. Mahmmoud, 2003, Annals of the New York Academy of Sciences.

Glutathionylation-Dependence of Na(+)-K(+)-Pump Currents Can Mimic Reduced Subsarcolemmal Na(+) Diffusion.

F. Cornelius, H. Rasmussen, R. Clarke, 2016, Biophysical journal.

Crystal structure of the sodium-potassium pump (Na+,K+-ATPase) with bound potassium and ouabain

C. Toyoshima, Takehiro Shinoda, H. Ogawa, 2009, Proceedings of the National Academy of Sciences.

Sequential substitution of K+ bound to Na+,K+-ATPase visualized by X-ray crystallography

C. Toyoshima, H. Ogawa, F. Cornelius, 2015, Nature Communications.

New crystal structures of PII-type ATPases: excitement continues.

C. Toyoshima, F. Cornelius, 2013, Current opinion in structural biology.

A Structural View on the Functional Importance of the Sugar Moiety and Steroid Hydroxyls of Cardiotonic Steroids in Binding to Na,K-ATPase*

C. Toyoshima, R. Kanai, F. Cornelius, 2013, The Journal of Biological Chemistry.

1 A STRUCTURAL VIEW ON THE FUNCTIONAL IMPORTANCE OF THE SUGAR MOIETY AND STEROID HYDROXYLS OF CARDIOTONIC STEROIDS IN BINDING TO Na , K-ATPase

C. Toyoshima, R. Kanai, F. Cornelius, 2013 .

Susceptibility of β1 Na+-K+ Pump Subunit to Glutathionylation and Oxidative Inhibition Depends on Conformational State of Pump*

G. Figtree, F. Cornelius, H. Rasmussen, 2012, The Journal of Biological Chemistry.

E2P phosphoforms of Na,K-ATPase. I. Comparison of phosphointermediates formed from ATP and Pi by their reactivity toward hydroxylamine and vanadate.

F. Cornelius, N. Fedosova, I. Kłodos, 1998, Biochemistry.

Modulation of Na,K-ATPase and Na-ATPase activity by phospholipids and cholesterol. I. Steady-state kinetics.

F. Cornelius, 2001, Biochemistry.

Cholesterol-dependent interaction of polyunsaturated phospholipids with Na,K-ATPase.

F. Cornelius, 2008, Biochemistry.

Cholesterol modulation of molecular activity of reconstituted shark Na+,K(+)-ATPase.

F. Cornelius, 1995, Biochimica et biophysica acta.

Reconstitution of (Na+ + K+)-ATPase into phospholipid vesicles with full recovery of its specific activity.

F. Cornelius, J. Skou, Jens Christian Skou, 1984, Biochimica et biophysica acta.

Functional regulation of reconstituted Na, K‐ATPase by protein kinase A phosphorylation

F. Cornelius, N. Logvinenko, Ninel Logvinenko, 1996, FEBS letters.

Reversible Oxidative Modification: A Key Mechanism of Na+-K+ Pump Regulation

G. Figtree, F. Cornelius, H. Rasmussen, 2009, Circulation research.

Dual mechanisms of allosteric acceleration of the Na(+),K(+)-ATPase by ATP.

F. Cornelius, R. Clarke, M. Khalid, 2010, Biophysical journal.

Interaction of ATP with the phosphoenzyme of the Na+,K+-ATPase.

H. Apell, F. Cornelius, R. Clarke, 2010, Biochemistry.

The sided action of Na+ on reconstituted shark Na+/K+-ATPase engaged in Na+-Na+ exchange accompanied by ATP hydrolysis. II. Transmembrane allosteric effects on Na+ affinity.

F. Cornelius, J. Skou, 1988, Biochimica et biophysica acta.

Capturing suboptical dynamic structures in lipid bilayer patches formed from free-standing giant unilamellar vesicles

F. Cornelius, J. Ipsen, T. Bhatia, 2017, Nature Protocols.

Intrinsic reaction-cycle time scale of Na+,K+-ATPase manifests itself in the lipid–protein interactions of nonequilibrium membranes

O. G. Mouritsen, H. Bouvrais, F. Cornelius, 2012, Proceedings of the National Academy of Sciences.

Investigation of the enzymatic activity of the Na+,K+-ATPase via isothermal titration microcalorimetry.

F. Cornelius, R. Clarke, Raimund Noske, 2010, Biochimica et biophysica acta.

Direct activation of gastric H,K-ATPase by N-terminal protein kinase C phosphorylation. Comparison of the acute regulation mechanisms of H,K-ATPase and Na,K-ATPase.

F. Cornelius, Y. Mahmmoud, 2003, Biophysical journal.

Phosphorylation/dephosphorylation of reconstituted shark Na+,K+-ATPase: one phosphorylation site per αβ protomer

F. Cornelius, 1995 .

Hydrophobic ion interaction on Na+ activation and dephosphorylation of reconstituted Na+,K(+)-ATPase.

F. Cornelius, 1995, Biochimica et biophysica acta.

Electrogenic pump current of sarcoplasmic reticulum Ca2+‐ATPase reconstituted at high lipid/protein ratio

J. Møller, F. Cornelius, 1991, FEBS letters.

Incorporation of C12E8-solubilized Na+,K+-ATPase into liposomes: determination of sidedness and orientation.

F. Cornelius, 1988, Methods in enzymology.

Na+-Na+ exchange mediated by (Na+ + K+)-ATPase reconstituted into liposomes. Evaluation of pump stoichiometry and response to ATP and ADP.

F. Cornelius, J. Skou, Jens Christian Skou, 1985, Biochimica et biophysica acta.

Cryo‐electron microscopy of Na+,K+‐ATPase reveals how the extracellular gate locks in the E2·2K+ state

C. Toyoshima, R. Kanai, F. Cornelius, 2022, FEBS letters.

Species-specific peculiarities of functional reactions of the sodium pump to phosphorylation by protein kinase A

F. Cornelius, N. Logvinenko, 2000, Journal of Evolutionary Biochemistry and Physiology.

Cis-allosteric effects of cytoplasmic Na+/K+ discrimination at varying pH. Low-affinity multisite inhibition of cytoplasmic K+ in reconstituted Na+/K(+)-ATPase engaged in uncoupled Na(+)-efflux.

F. Cornelius, 1992, Biochimica et biophysica acta.

Polarity of the ATP binding site of the Na+,K+-ATPase, gastric H+,K+-ATPase and sarcoplasmic reticulum Ca2+-ATPase.

T. Zhang, X. Li, F. Cornelius, 2019, Biochimica et biophysica acta. Biomembranes.

Metal Fluoride Complexes of Na,K-ATPase

C. Toyoshima, F. Cornelius, Y. Mahmmoud, 2011, The Journal of Biological Chemistry.

Inhibition of K+ Transport through Na+, K+-ATPase by Capsazepine: Role of Membrane Span 10 of the α-Subunit in the Modulation of Ion Gating

M. Shattock, F. Cornelius, D. Pavlovic, 2014, PloS one.

University of Birmingham Inhibition of K+ transport through Na+, K+-ATPase by capsazepine

M. Shattock, F. Cornelius, D. Pavlovic, 2014 .

The voltage-sensitive dye RH421 detects a Na+,K+-ATPase conformational change at the membrane surface.

T. Allen, F. Cornelius, D. Jacquemin, 2017, Biochimica et biophysica acta. Biomembranes.

Membrane accessibility of glutathione.

H. Khandelia, F. Cornelius, F. Separovic, 2015, Biochimica et Biophysica Acta.

Identification of electric-field-dependent steps in the Na(+),K(+)-pump cycle.

T. Allen, F. Cornelius, H. Rasmussen, 2014, Biophysical journal.

Cholesterol depletion inhibits Na+,K+-ATPase activity in a near-native membrane environment

T. Allen, F. Cornelius, B. Lev, 2019, The Journal of Biological Chemistry.

Functional reconstitution of the sodium pump. Kinetics of exchange reactions performed by reconstituted Na/K-ATPase.

F. Cornelius, 1991, Biochimica et biophysica acta.

The sodium PUMP

F. Cornelius, 1996 .

Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state

C. Toyoshima, R. Kanai, H. Ogawa, 2013, Nature.

Binding of cardiotonic steroids to Na+,K+-ATPase in the E2P state

C. Toyoshima, R. Kanai, H. Ogawa, 2020, Proceedings of the National Academy of Sciences.

General and specific lipid-protein interactions in Na,K-ATPase.

M. Habeck, C. Toyoshima, R. Kanai, 2015, Biochimica et biophysica acta.

Tension-length behaviour of a molluscan smooth muscle related to filament organisation.

J. Lowy, F. Cornelius, 1978, Acta physiologica Scandinavica.

The regulation of tension in a chemically skinned molluscan smooth muscle: effect of Mg2+ on the Ca2+-activated tension generation

F. Cornelius, 1980, The Journal of general physiology.

Inorganic phosphate in Ehrlich ascites tumor cells and its distribution across the cell membrane.

F. Cornelius, L. Simonsen, 1978, Biochimica et biophysica acta.

Peptide Ligation at High Dilution via Reductive Diselenide-Selenoester Ligation.

R. Payne, F. Cornelius, Sameer S. Kulkarni, 2019, Journal of the American Chemical Society.

Displacement of Native FXYD Protein From Na+/K+-ATPase With Novel FXYD Peptide Derivatives: Effects on Doxorubicin Cytotoxicity

R. Baxter, F. Cornelius, H. Rasmussen, 2022, Frontiers in Oncology.

K+-dependence of electrogenic transport by the NaK-ATPase.

F. Cornelius, K. Fendler, T. Gropp, 1998, Biochimica et biophysica acta.

Protein Kinase C Phosphorylation of Purified Na,K-ATPase: C-Terminal Phosphorylation Sites at the α- and γ-Subunits Close to the Inner Face of the Plasma Membrane

F. Cornelius, Y. Mahmmoud, 2002 .

Protein kinase C phosphorylation of purified Na,K-ATPase: C-terminal phosphorylation sites at the alpha- and gamma-subunits close to the inner face of the plasma membrane.

F. Cornelius, Y. Mahmmoud, 2002, Biophysical journal.

Distinct pH dependencies of Na+/K+ selectivity at the two faces of Na,K-ATPase

C. Toyoshima, F. Cornelius, N. Tsunekawa, 2017, The Journal of Biological Chemistry.

A voltage-activated cation transport pathway associated with the sodium pump.

F. Cornelius, J. Halperin, 1991, Biochimica et biophysica acta.

Identification of a Phospholemman-like Protein from Shark Rectal Glands

H. Vorum, F. Cornelius, Y. Mahmmoud, 2000, The Journal of Biological Chemistry.

ATP binding equilibria of the Na(+),K(+)-ATPase.

J. Matthews, H. Apell, P. Sebban, 2008, Biochemistry.

Penetration of phospholipid membranes by poly-l-lysine depends on cholesterol and phospholipid composition.

F. Cornelius, R. Clarke, Amy Gorman, 2019, Biochimica et biophysica acta. Biomembranes.

Regulation of Na,K-ATPase by PLMS, the Phospholemman-like Protein from Shark

F. Cornelius, A. B. Maunsbach, C. Cutler, 2003, Journal of Biological Chemistry.

Variable stoichiometry in reconstituted shark Na,K-ATPase engaged in uncoupled efflux.

F. Cornelius, 1990, Biochimica et biophysica acta.

Spatial distribution and activity of Na(+)/K(+)-ATPase in lipid bilayer membranes with phase boundaries.

L. Bagatolli, F. Cornelius, J. Ipsen, 2016, Biochimica et biophysica acta.

Modulation of Na,K-ATPase by phospholipids and cholesterol. II. Steady-state and presteady-state kinetics.

F. Cornelius, N. Turner, H. Christensen, 2003, Biochemistry.

University of Southern Denmark Spatial distribution and activity of Na +/K +-ATPase in lipid bilayer membranes with phase boundaries Bhartia,

L. Bagatolli, F. Cornelius, J. Ipsen, 2016 .

Interaction between cardiotonic steroids and Na,K-ATPase. Effects of pH and ouabain-induced changes in enzyme conformation.

F. Cornelius, Y. Mahmmoud, 2009, Biochemistry.

FXYD Proteins Reverse Inhibition of the Na+-K+ Pump Mediated by Glutathionylation of Its β1 Subunit*

K. Geering, G. Figtree, F. Marassi, 2011, The Journal of Biological Chemistry.

Rb(+) occlusion stabilized by vanadate in gastric H(+)/K(+)-ATPase at 25°C.

F. Cornelius, P. J. Garrahan, M. Montes, 2011, Biochimica et biophysica acta.

Mechanism of Mg2+ binding in the Na+,K+-ATPase.

P. Kuchel, P. Sebban, F. Cornelius, 2009, Biophysical journal.

Exploring the raft-hypothesis by probing planar bilayer patches of free-standing giant vesicles at nanoscale resolution, with and without Na,K-ATPase.

F. Cornelius, J. Ipsen, T. Bhatia, 2016, Biochimica et biophysica acta.

Mechanism of the rate-determining step of the Na(+),K(+)-ATPase pump cycle.

H. Apell, F. Cornelius, C. Lüpfert, 2002, Biochemistry.

Electrostatic Stabilization Plays a Central Role in Autoinhibitory Regulation of the Na+,K+-ATPase.

H. Khandelia, H. Apell, F. Cornelius, 2017, Biophysical journal.

Kinetics of K(+) occlusion by the phosphoenzyme of the Na(+),K(+)-ATPase.

H. Apell, F. Cornelius, R. Clarke, 2011, Biophysical journal.

Active Biomimetic Membranes

F. Cornelius, 2011 .

Kinetic Investigations of the Mechanism of the Rate‐Determining Step of the Na+,K+‐ATPase Pump Cycle

H. Apell, F. Cornelius, C. Lüpfert, 2003, Annals of the New York Academy of Sciences.

Rate limitation of the Na(+),K(+)-ATPase pump cycle.

V. Pintschovius, H. Apell, F. Cornelius, 2001, Biophysical journal.

Rate determination in phosphorylation of shark rectal Na,K-ATPase by ATP: temperature sensitivity and effects of ADP.

F. Cornelius, 1999, Biophysical journal.

Tonic contraction and the control of relaxation in a chemically skinned molluscan smooth muscle

F. Cornelius, 1982, The Journal of general physiology.

Modulation of Na,K-ATPase by Associated Small Transmembrane Regulatory Proteins and by Lipids

F. Cornelius, H. Christensen, Flemming Cornelius, 2001, Journal of bioenergetics and biomembranes.

The effect of cytoplasmic K+ on the activity of the Na+/K(+)-ATPase.

F. Cornelius, J. Skou, 1991, Biochimica et Biophysica Acta.

Uncoupled Na+-efflux on reconstituted shark Na,K-ATPase is electrogenic.

F. Cornelius, 1989, Biochemical and biophysical research communications.

The sided action of Na+ and of K+ on reconstituted shark (Na+ + K+)-ATPase engaged in Na+-Na+ exchange accompanied by ATP hydrolysis. I. The ATP activation curve.

F. Cornelius, J. Skou, 1987, Biochimica et biophysica acta.

Species-specific peculiarities of functional reactions of the sodium pump to phosphorylation by protein kinase A

F. Cornelius, N. Logvinenko, 2008, Journal of Evolutionary Biochemistry and Physiology.

LIPOSOMES IN RECONSTITUTION OF ION-PUMPS. ELECTROGENIC PROPERTIES OF THE Na+,K+-ATPase AND THE SARCOPLASMIC Ca2*-ATPase.

F. Cornelius, 1995 .

Phosphorylation/dephosphorylation of reconstituted shark Na+,K(+)-ATPase: one phosphorylation site per alpha beta protomer.

F. Cornelius, 1995, Biochimica et biophysica acta.

Electrogenicity and Countertransport Properties of Reconstituted Sarcoplasmic Reticulum Ca2+-ATPase

J. Møller, F. Cornelius, 1994 .

Functional modulation of the sodium pump: the regulatory proteins "Fixit".

F. Cornelius, Y. Mahmmoud, 2003, News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society.

Interaction of N-terminal peptide analogues of the Na+,K+-ATPase with membranes.

V. Dubey, H. Khandelia, R. Payne, 2018, Biochimica et biophysica acta. Biomembranes.

Cryoelectron microscopy of Na+,K+-ATPase in the two E2P states with and without cardiotonic steroids

C. Toyoshima, R. Kanai, F. Cornelius, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Na+/K+-ATPase-associated FXYD3 Protein As An Intracellular Therapeutic Target in Cancer

R. Baxter, F. Cornelius, H. Rasmussen, 2020 .

Functional significance of the shark Na,K-ATPase N-terminal domain. Is the structurally variable N-Terminus involved in tissue-specific regulation by FXYD proteins?

F. Cornelius, G. Cramb, Y. Mahmmoud, 2005, Biochemistry.

Fluorescent styryl dyes as probes for Na,K-ATPase reaction mechanism: significance of the charge of the hydrophilic moiety of RH dyes.

F. Cornelius, N. Fedosova, I. Kłodos, 1995, Biochemistry.

Crystal structures of Na+,K+‐ATPase reveal the mechanism that converts the K+‐bound form to Na+‐bound form and opens and closes the cytoplasmic gate

C. Toyoshima, R. Kanai, F. Cornelius, 2023, FEBS letters.

Electrostatic Stabilization Plays a Central Role in Autoinhibitory Regulation of the Na+,K+-ATPase.

H. Khandelia, H. Apell, F. Cornelius, 2017, Biophysical journal.

Involvement of the alpha-subunit N-terminus in the mechanism of the Na+,K+-ATPase.

T. Allen, C. Cranfield, F. Cornelius, 2023, Biochimica et biophysica acta. Molecular cell research.

Cholesterol depletion inhibits Na (cid:2) ,K (cid:2) -ATPase activity in a near-native membrane environment

F. Cornelius, Amy Gorman, K. R. Hossain, 2020 .

Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state

C. Toyoshima, R. Kanai, H. Ogawa, 2013, Nature.

Rate limitation of the Na(+),K(+)-ATPase pump cycle.

H. Apell, F. Cornelius, E. Grell, 2001, Biophysical journal.

ATP binding equilibria of the Na(+),K(+)-ATPase.

J. Matthews, H. Apell, P. Sebban, 2008, Biochemistry.