A. Maeda

发表

Conditional Ablation of Retinol Dehydrogenase 10 in the Retinal Pigmented Epithelium Causes Delayed Dark Adaption in Mice*

K. Palczewski, M. Griswold, Y. Le, 2015, The Journal of Biological Chemistry.

Key enzymes of the retinoid (visual) cycle in vertebrate retina.

K. Palczewski, M. Golczak, P. Kiser, 2012, Biochimica et biophysica acta.

All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis.

T. Maeda, Lindsay Perusek, A. Maeda, 2014, Experimental eye research.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Autophagy in light-induced retinal damage.

Lindsay Perusek, A. Maeda, Yu Chen, 2016, Experimental eye research.

Primary amines protect against retinal degeneration in mouse models of retinopathies

K. Palczewski, M. Golczak, T. Maeda, 2011, Nature chemical biology.

Involvement of All-trans-retinal in Acute Light-induced Retinopathy of Mice*

K. Palczewski, C. Hoppel, M. Golczak, 2009, Journal of Biological Chemistry.

Metabolic Basis of Visual Cycle Inhibition by Retinoid and Nonretinoid Compounds in the Vertebrate Retina*

K. Palczewski, W. Blaner, M. Golczak, 2008, Journal of Biological Chemistry.

Retinopathy in Mice Induced by Disrupted All-trans-retinal Clearance*

K. Palczewski, M. Golczak, T. Maeda, 2008, Journal of Biological Chemistry.

Sector retinitis pigmentosa: Report of ten cases and a review of the literature

A. Maeda, E. Traboulsi, M. DeBenedictis, 2019, Molecular vision.

Development of a molecular diagnostic test for Retinitis Pigmentosa in the Japanese population

O. Ohara, S. Takagi, Y. Hirami, 2018, Japanese Journal of Ophthalmology.

Retinal degeneration in animal models with a defective visual cycle.

K. Palczewski, A. Maeda, 2013, Drug discovery today. Disease models.

Effect of dietary docosahexaenoic acid on rhodopsin content and packing in photoreceptor cell membranes.

M. Gragg, P. Park, Vipul M. Parmar, 2018, Biochimica et biophysica acta. Biomembranes.

Self-Assembly of a Multifunctional Lipid With Core-Shell Dendrimer DNA Nanoparticles Enhanced Efficient Gene Delivery at Low Charge Ratios into RPE Cells.

K. Palczewski, Rebecca M. Schur, Zheng-Rong Lu, 2015, Macromolecular bioscience.

Rhodopsin Signaling and Organization in Heterozygote Rhodopsin Knockout Mice*

A. Engel, K. Palczewski, S. Filipek, 2004, Journal of Biological Chemistry.

Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration.

K. Palczewski, D. Mustafi, M. Golczak, 2013, The Journal of clinical investigation.

Serum levels of lipid metabolites in age‐related macular degeneration

K. Palczewski, T. Maeda, A. Maeda, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Genetic Spectrum of EYS-associated Retinal Disease in a Large Japanese Cohort: Identification of Disease-associated Variants with Relatively High Allele Frequency

Y. Hayashizaki, M. Itoh, H. Kawaji, 2020, Scientific Reports.

Retinitis Pigmentosa with EYS Mutations Is the Most Prevalent Inherited Retinal Dystrophy in Japanese Populations

M. Mandai, Y. Hirami, Masayo Takahashi, 2015, Journal of ophthalmology.

Effects of long-term administration of 9-cis-retinyl acetate on visual function in mice.

K. Palczewski, D. Saperstein, T. Maeda, 2009, Investigative ophthalmology & visual science.

Effects of Potent Inhibitors of the Retinoid Cycle on Visual Function and Photoreceptor Protection from Light Damage in Mice

K. Palczewski, Y. Imanishi, M. Golczak, 2006, Molecular Pharmacology.

Retinol Dehydrogenases Regulate Vitamin A Metabolism for Visual Function

Bhubanananda Sahu, A. Maeda, 2016, Nutrients.

A ROCK Inhibitor Promotes Graft Survival during Transplantation of iPS-Cell-Derived Retinal Cells

M. Mandai, Masayo Takahashi, Shota Fujii, 2021, International journal of molecular sciences.

Clinical and Genetic Characteristics of 18 Patients from 13 Japanese Families with CRX-associated retinal disorder: Identification of Genotype-phenotype Association

Y. Hayashizaki, H. Kawaji, K. Tsubota, 2020, Scientific Reports.

Frequent detection of anti-recoverin cytotoxic T-lymphocyte precursors in peripheral blood of cancer patients by using an HLA-Aff24-recoverin tetramer

N. Sato, Y. Hirohashi, H. Sahara, 2002, Cancer Immunology, Immunotherapy.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Prolonged prevention of retinal degeneration with retinylamine loaded nanoparticles.

K. Palczewski, Zheng-Rong Lu, M. Golczak, 2015, Biomaterials.

Lipocalin 2 Plays an Important Role in Regulating Inflammation in Retinal Degeneration

Masayo Takahashi, Lindsay Perusek, Vipul M. Parmar, 2018, The Journal of Immunology.

An HLA-A24-restricted cytotoxic T lymphocyte epitope of a tumor-associated protein, survivin.

K. Kamiguchi, N. Sato, Y. Hirohashi, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Palmitoylation stabilizes unliganded rod opsin

K. Palczewski, P. Park, T. Maeda, 2010, Proceedings of the National Academy of Sciences.

Aberrantly expressed recoverin is functionally associated with G-protein-coupled receptor kinases in cancer cell lines.

M. Sasaki, T. Maeda, A. Maeda, 2002, Biochemical and biophysical research communications.

Peptide Derivatives of Retinylamine Prevent Retinal Degeneration with Minimal Side Effects on Vision in Mice.

K. Palczewski, Zheng-Rong Lu, P. Fu, 2021, Bioconjugate chemistry.

Molecular biology and analytical chemistry methods used to probe the retinoid cycle.

K. Palczewski, M. Golczak, A. Maeda, 2010, Methods in molecular biology.

Retinyl Ester Homeostasis in the Adipose Differentiation-related Protein-deficient Retina*

K. Palczewski, Y. Imanishi, T. Maeda, 2008, Journal of Biological Chemistry.

Redundant and unique roles of retinol dehydrogenases in the mouse retina

K. Palczewski, T. Maeda, Wenyu Sun, 2007, Proceedings of the National Academy of Sciences.

Mechanism Of All-Trans-retinal Toxicity: Implications For Stargardt’S Disease And Age-related Macular Degeneration

K. Palczewski, M. Golczak, T. Maeda, 2012 .

Retinal dysfunction in cancer-associated retinopathy is improved by Ca(2+) antagonist administration and dark adaptation.

T. Maeda, A. Maeda, H. Ohguro, 2001, Investigative ophthalmology & visual science.

[Molecular mechanism of cancer-associated retinopathy and tumor antigens].

N. Sato, A. Maeda, H. Ohguro, 2000, Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology.

Non-commercial Research and Educational Use including without Limitation Use in Instruction at Your Institution, Sending It to Specific Colleagues That You Know, and Providing a Copy to Your Institution's Administrator. All Other Uses, Reproduction and Distribution, including without Limitation Comm

Krzysztof Palczewski, Akiko Maeda, Christina Gerth, 2022 .

Photoreceptor Proteins Initiate Microglial Activation via Toll-like Receptor 4 in Retinal Degeneration Mediated by All-trans-retinal*

M. Miyagi, K. Palczewski, B. Kevany, 2013, The Journal of Biological Chemistry.

Limited roles of Rdh8, Rdh12, and Abca4 in all-trans-retinal clearance in mouse retina.

K. Palczewski, M. Golczak, T. Maeda, 2009, Investigative ophthalmology & visual science.

Evaluation of 9-cis-retinyl acetate therapy in Rpe65-/- mice.

G. Casadesus, K. Palczewski, T. Maeda, 2009, Investigative ophthalmology & visual science.

Docosahexaenoic acid promotes differentiation of photoreceptor cells in three-dimensional neural retinas

Bhubanananda Sahu, Lindsay Perusek, Vipul M. Parmar, 2017, Neuroscience Research.

Noninvasive multi–photon fluorescence microscopy resolves retinol and retinal–condensation products in mouse eyes

David R. Williams, Krzysztof Palczewski, Yoshikazu Imanishi, 2010, Nature Medicine.

Retinal Pigmented Epithelial Cells Obtained from Human Induced Pluripotent Stem Cells Possess Functional Visual Cycle Enzymes in Vitro and in Vivo*

K. Palczewski, P. Tesar, Masayo Takahashi, 2013, The Journal of Biological Chemistry.

Mechanism of All-trans-retinal Toxicity with Implications for Stargardt Disease and Age-related Macular Degeneration*

Krzysztof Palczewski, Akiko Maeda, Tadao Maeda, 2011, Journal of Biological Chemistry.

Clinical and Genetic Characteristics of 18 Patients from 13 Japanese Families with CRX-associated retinal disorder: Identification of Genotype-phenotype Association

Y. Hayashizaki, H. Kawaji, K. Tsubota, 2020, Scientific Reports.

Inducing human retinal pigment epithelium-like cells from somatic tissue

C. Hon, Piero Carninci, B. Kaczkowski, 2020, bioRxiv.

A2E-associated cell death and inflammation in retinal pigmented epithelial cells from human induced pluripotent stem cells

Lindsay Perusek, Vipul M. Parmar, A. Maeda, 2018, Stem cell research.

Detection and Induction of CTLs Specific for SYT-SSX-Derived Peptides in HLA-A24+ Patients with Synovial Sarcoma1

T. Yamashita, N. Araki, S. Ichimiya, 2002, The Journal of Immunology.

Patients with Synovial Sarcoma + SYT-SSX-Derived Peptides in HLA-A 24 Detection and Induction of CTLs Specific for and Noriyuki

T. Yamashita, N. Araki, S. Ichimiya, 2002 .

Microsomal glutathione S-transferase 1 in the retinal pigment epithelium: protection against oxidative stress and a potential role in aging.

K. Palczewski, A. Maeda, J. Crabb, 2005, Biochemistry.

DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice

K. Palczewski, Xiaodong Bai, D. Mustafi, 2014, The FASEB Journal.

MicroRNA-processing Enzymes Are Essential for Survival and Function of Mature Retinal Pigmented Epithelial Cells in Mice*

K. Palczewski, Sanae Sakami, M. Golczak, 2017, The Journal of Biological Chemistry.

RPE Visual Cycle and Biochemical Phenotypes of Mutant Mouse Models.

Bhubanananda Sahu, A. Maeda, 2018, Methods in molecular biology.

The role of retinol dehydrogenase 10 in the cone visual cycle

J. Corbo, K. Palczewski, D. Hodzic, 2017, Scientific Reports.

Retinol dehydrogenase 8 and ATP‐binding cassette transporter 4 modulate dark adaptation of M‐cones in mammalian retina

K. Palczewski, Y. Imanishi, A. Kolesnikov, 2015, The Journal of physiology.

Retinal Photodamage Mediated by All‐trans‐retinal †

M. Golczak, T. Maeda, A. Maeda, 2012, Photochemistry and photobiology.

Retinol Dehydrogenase (RDH12) Protects Photoreceptors from Light-induced Degeneration in Mice*

K. Palczewski, Y. Imanishi, T. Maeda, 2006, Journal of Biological Chemistry.

Role of Photoreceptor-specific Retinol Dehydrogenase in the Retinoid Cycle in Vivo*

J. D. Bronson, F. Rieke, K. Palczewski, 2005, Journal of Biological Chemistry.

Delayed Dark Adaptation in 11-cis-Retinol Dehydrogenase-deficient Mice

P. Nelson, K. Palczewski, C. Heinlein, 2005, Journal of Biological Chemistry.

Low expression of alphaA-crystallins and rhodopsin kinase of photoreceptors in retinal dystrophy rat.

T. Maeda, Y. Kuroki, A. Maeda, 1999, Investigative ophthalmology & visual science.

Acute Stress Responses Are Early Molecular Events of Retinal Degeneration in Abca4−/−Rdh8−/− Mice After Light Exposure

Bhubanananda Sahu, Lindsay Perusek, Vipul M. Parmar, 2016, Investigative ophthalmology & visual science.

Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium*

K. Palczewski, Y. Le, Bhubanananda Sahu, 2015, The Journal of Biological Chemistry.

Manganese-Enhanced MRI for Preclinical Evaluation of Retinal Degeneration Treatments.

Xin Yu, K. Palczewski, Rebecca M. Schur, 2015, Investigative ophthalmology & visual science.

Toll-like Receptor 3 Is Required for Development of Retinopathy Caused by Impaired All-trans-retinal Clearance in Mice*

K. Palczewski, T. Maeda, A. Maeda, 2011, The Journal of Biological Chemistry.

Evaluation of potential therapies for a mouse model of human age-related macular degeneration caused by delayed all-trans-retinal clearance.

K. Palczewski, T. Maeda, A. Maeda, 2009, Investigative ophthalmology & visual science.

Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate.

T. Aleman, A. Cideciyan, S. Jacobson, 2009, Human molecular genetics.

Receptor MER Tyrosine Kinase Proto-oncogene (MERTK) Is Not Required for Transfer of Bis-retinoids to the Retinal Pigmented Epithelium*

K. Palczewski, B. Kevany, M. Golczak, 2016, The Journal of Biological Chemistry.

CCL3 Production by Microglial Cells Modulates Disease Severity in Murine Models of Retinal Degeneration

T. Maeda, Lindsay Perusek, A. Maeda, 2014, The Journal of Immunology.

Two-photon microscopy reveals early rod photoreceptor cell damage in light-exposed mutant mice

K. Palczewski, M. Golczak, T. Maeda, 2014, Proceedings of the National Academy of Sciences.

Modeling Retinal Diseases Using Genetic Approaches in Mice.

T. Maeda, A. Maeda, 2018, Methods in molecular biology.

Non-viral Gene Therapy for Stargardt Disease with ECO/pRHO-ABCA4 Self-Assembled Nanoparticles.

K. Palczewski, Rebecca M. Schur, Zheng-Rong Lu, 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations.

Krzysztof Palczewski, Edwin M Stone, Ning Zhang, 2015, Human molecular genetics.

Importance of Membrane Structural Integrity for RPE65 Retinoid Isomerization Activity*

K. Palczewski, M. Golczak, P. Kiser, 2010, The Journal of Biological Chemistry.

Vaccination with recoverin, a cancer‐associated retinopathy antigen, induces autoimmune retinal dysfunction and tumor cell regression in mice

K. Palczewski, N. Sato, T. Maeda, 2002, European journal of immunology.

New GABA modulators protect photoreceptor cells from light‐induced degeneration in mouse models

K. Palczewski, Rebecca M. Schur, Zheng-Rong Lu, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Identification of human antitumor cytotoxic T lymphocytes epitopes of recoverin, a cancer‐associated retinopathy antigen, possibly related with a better prognosis in a paraneoplastic syndrome

Y. Nishimura, N. Sato, T. Maeda, 2001, European journal of immunology.

Targeted Multifunctional Lipid ECO Plasmid DNA Nanoparticles as Efficient Non-viral Gene Therapy for Leber’s Congenital Amaurosis

K. Palczewski, Rebecca M. Schur, Zheng-Rong Lu, 2017, Molecular therapy. Nucleic acids.

Retinal cone and rod photoreceptor cells exhibit differential susceptibility to light‐induced damage

K. Palczewski, T. Maeda, A. Maeda, 2012, Journal of neurochemistry.

Essential role of Ca2+-binding protein 4, a Cav1.4 channel regulator, in photoreceptor synaptic function

F. Rieke, K. Palczewski, Y. Imanishi, 2004, Nature Neuroscience.

Effects of cytotoxic T lymphocyte antigen 4 (CTLA4) signaling and locally applied steroid on retinal dysfunction by recoverin, cancer-associated retinopathy antigen.

D. Saperstein, T. Maeda, A. Maeda, 2006, Molecular vision.

Aberrant expression of photoreceptor-specific calcium-binding protein (recoverin) in cancer cell lines.

N. Sato, I. Wada, T. Maeda, 2000, Cancer research.

Mechanisms of photoreceptor cell death in cancer-associated retinopathy.

N. Sato, T. Maeda, H. Sahara, 2001, Investigative ophthalmology & visual science.

Autophagy Protects the Retina from Light-induced Degeneration*

Y. Le, T. Maeda, A. Maeda, 2013, The Journal of Biological Chemistry.

Aberrant metabolites in mouse models of congenital blinding diseases: formation and storage of retinyl esters.

K. Palczewski, Y. Imanishi, M. Golczak, 2006, Biochemistry.

Truncating Variants Contribute to Hearing Loss and Severe Retinopathy in USH2A-Associated Retinitis Pigmentosa in Japanese Patients

Y. Hirami, Masayo Takahashi, Y. Kurimoto, 2020, International journal of molecular sciences.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Adaptations in rod outer segment disc membranes in response to environmental lighting conditions.

T. Rakshit, P. Park, Bhubanananda Sahu, 2017, Biochimica et biophysica acta. Molecular cell research.

Kinetic, energetic, and mechanical differences between dark-state rhodopsin and opsin.

M. Gerstung, N. Beerenwinkel, D. Müller, 2013, Structure.

Modulation of molecular interactions and function by rhodopsin palmitylation.

K. Palczewski, S. Filipek, D. Müller, 2009, Biochemistry.

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

Ocular biometry with swept-source optical coherence tomography-based optical biometer in Japanese patients with EYS-related retinitis pigmentosa: a retrospective study

Y. Hirami, Y. Kurimoto, Makoto Nakamura, 2022, BMC Ophthalmology.

Synthesis and evaluation of a nanoglobular dendrimer 5-aminosalicylic Acid conjugate with a hydrolyzable schiff base spacer for treating retinal degeneration.

K. Palczewski, Zhuxian Zhou, Zheng-Rong Lu, 2014, ACS nano.

Multifunctional PEG Retinylamine Conjugate Provides Prolonged Protection against Retinal Degeneration in Mice

K. Palczewski, M. Golczak, Xueming Wu, 2014, Biomacromolecules.

Cancer-associated retinopathy induced by both anti-recoverin and anti-hsc70 antibodies in vivo.

T. Maeda, A. Maeda, H. Ohguro, 1999, Investigative ophthalmology & visual science.

Gene and Induced Pluripotent Stem Cell Therapy for Retinal Diseases.

M. Mandai, Masayo Takahashi, A. Maeda, 2019, Annual review of genomics and human genetics.

A CASE OF RAPIDLY PROGRESSIVE RETINOPATHY ASSOCIATED WITH PEMBROLIZUMAB IMMUNOTHERAPY FOR METASTATIC UROTHELIAL CARCINOMA

Y. Hirami, Y. Kurimoto, S. Sugita, 2022, Retinal cases & brief reports.

Improvement in rod and cone function in mouse model of Fundus albipunctatus after pharmacologic treatment with 9-cis-retinal.

K. Palczewski, T. Maeda, A. Maeda, 2006, Investigative ophthalmology & visual science.

Mechanism of All-trans-retinal Toxicity with Implications for Stargardt Disease and Age-related Macular Degeneration*

K. Palczewski, M. Golczak, T. Maeda, 2011, The Journal of Biological Chemistry.

Autophagy Protects the Retina from Light-induced Degeneration*

Y. Le, T. Maeda, A. Maeda, 2013, The Journal of Biological Chemistry.

Involvement of All-trans-retinal in Acute Light-induced Retinopathy of Mice*

K. Palczewski, C. Hoppel, M. Golczak, 2009, Journal of Biological Chemistry.

CCL3 Production by Microglial Cells Modulates Disease Severity in Murine Models of Retinal Degeneration

T. Maeda, Lindsay Perusek, A. Maeda, 2014, The Journal of Immunology.

New GABA modulators protect photoreceptor cells from light‐induced degeneration in mouse models

K. Palczewski, Rebecca M. Schur, Zheng-Rong Lu, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate.

T. Aleman, A. Cideciyan, S. Jacobson, 2009, Human molecular genetics.

Supplementation with vitamin a derivatives to rescue vision in animal models of degenerative retinal diseases.

T. Maeda, Lindsay Perusek, A. Maeda, 2015, Methods in molecular biology.

Effects of long-term administration of 9-cis-retinyl acetate on visual function in mice.

K. Palczewski, D. Saperstein, T. Maeda, 2009, Investigative ophthalmology & visual science.

Adaptations in rod outer segment disc membranes in response to environmental lighting conditions.

T. Rakshit, Bhubanananda Sahu, Vipul M. Parmar, 2017, Biochimica et biophysica acta. Molecular cell research.

Of Retinal Degeneration Models Modulates Disease Severity in Murine Ccl3 Production by Microglial Cells

T. Maeda, Lindsay Perusek, A. Maeda, 2022 .

Novel RDH12 mutations associated with Leber congenital amaurosis and cone-rod dystrophy: Biochemical and clinical evaluations

K. Palczewski, D. Saperstein, E. Héon, 2007, Vision Research.